L-Citrulline dilates rat retinal arterioles via nitric oxide- and prostaglandin-dependent pathways in vivo

Journal of Pharmacological Sciences

Volumn 127, Issue 4, 2015, Pages 419-423

  Mori, Asami ^a   Morita, Masahiko ^b   Morishita, Koji ^b   Sakamoto, Kenji ^a   Nakahara, Tsutomu ^a   Ishii, Kunio ^a  

^a KITASATO UNIVERSITY   (Japan)

^b KYOWA HAKKO BIO CO   (Japan)

Author keywords

Cyclooxygenase; L Citrulline; Nitric oxide; Retinal blood vessel

Indexed keywords

ARGININE; CITRULLINE; INDOMETACIN; N METHYL DEXTRO ASPARTIC ACID; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PROSTAGLANDIN; ARGININOSUCCINATE SYNTHASE; ENZYME INHIBITOR; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIOLE; ARTERY DILATATION; ARTICLE; BLOOD VESSEL DIAMETER; BLOOD VESSEL TONE; CONTROLLED STUDY; DRUG MECHANISM; EYE FUNDUS; HEART RATE; IN VIVO STUDY; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; RAT; RETINA BLOOD FLOW; RETINA BLOOD VESSEL; SIGNAL TRANSDUCTION; VASCULAR RESISTANCE; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; RETINA ARTERY; VASODILATATION; WISTAR RAT;

ANIMALS; ARGININE; ARGININOSUCCINATE SYNTHASE; CITRULLINE; CYCLOOXYGENASE INHIBITORS; ENZYME INHIBITORS; INDOMETHACIN; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROSTAGLANDINS; RATS, WISTAR; RETINAL ARTERY; SIGNAL TRANSDUCTION; VASODILATION;

EID: 84936861914     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1016/j.jphs.2015.02.012     Document Type: Article

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