Ambient fine particulate matter suppresses in vivo proliferation of bone marrow stem cells through reactive oxygen species formation

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Cui, Yuqi ^a,b   Jia, Fengpeng ^a,e   He, Jianfeng ^a   Xie, Xiaoyun ^a   Li, Zhihong ^a   Fu, Minghuan ^a   Hao, Hong ^a   Liu, Ying ^a   Liu, Dylan Z ^a   Cowan, Peter J ^d   Zhu, Hua ^a,c   Sun, Qinghua ^a   Liu, Zhenguo ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b SHANDONG UNIVERSITY   (China)

^c THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; BROXURIDINE; COPPER ZINC SUPEROXIDE DISMUTASE; EXTRACELLULAR SUPEROXIDE DISMUTASE; GLUTATHIONE PEROXIDASE 1; LIPOCORTIN 5; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; ANTIOXIDANT; PARTICULATE MATTER;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; C57BL 6 MOUSE; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PARTICULATE MATTER; PROLIFERATION INHIBITION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; WESTERN BLOTTING; WILD TYPE; ANIMAL; BONE MARROW CELL; C57BL MOUSE; CYTOLOGY; DRUG EFFECTS; INTRACELLULAR SPACE; METABOLISM; PHOSPHORYLATION; STEM CELL; TOXICITY;

MUS; MUS MUSCULUS;

ACETYLCYSTEINE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; BONE MARROW CELLS; CELL PROLIFERATION; INTRACELLULAR SPACE; MALE; MICE, INBRED C57BL; PARTICULATE MATTER; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; STEM CELLS;

EID: 84936803086     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0127309     Document Type: Article

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