Mechanism-based classification of PAH mixtures to predict carcinogenic potential

Toxicological Sciences

Volumn 146, Issue 1, 2015, Pages 135-145

  Tilton, Susan C ^a   Siddens, Lisbeth K ^a   Krueger, Sharon K ^a,b   Larkin, Andrew J ^a   Löhr, Christiane V ^a   Williams, David E ^a,b   Baird, William M ^a   Waters, Katrina M ^a,c  

^a OREGON STATE UNIVERSITY   (United States)

^b OREGON STATE UNIVERSITY   (United States)

^c PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

Mixtures; Modeling; Polycyclic aromatic hydrocarbons; Skin cancer; Toxicogenomics

Indexed keywords

BENZO[A]PYRENE; DIBENZO[DEF,P]CHRYSENE; GAMMA INTERFERON; POLYCYCLIC AROMATIC HYDROCARBON; UNCLASSIFIED DRUG; CARCINOGEN;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BAYES THEOREM; CANCER INCIDENCE; CANCER PROGNOSIS; CARCINOGENESIS; CARCINOGENIC ACTIVITY; CLASSIFICATION; CONTROLLED STUDY; DNA DAMAGE; ENVIRONMENTAL EXPOSURE; FEMALE; GENE EXPRESSION PROFILING; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; RISK ASSESSMENT; SIGNAL TRANSDUCTION; SKIN TUMOR; STIMULUS RESPONSE; VALIDATION STUDY; ANIMAL;

MUS;

ANIMALS; CARCINOGENS; MICE; POLYCYCLIC AROMATIC HYDROCARBONS;

EID: 84936766359     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfv080     Document Type: Article

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