Toll-like receptor 4 gene polymorphism downregulates gene expression and involves in susceptibility to bladder cancer

Tumor Biology

Volumn 36, Issue 4, 2015, Pages 2779-2784

  Shen, Yizhen ^a,b   Bu, Meimei ^a,b   Zhang, Aimin ^a,b   Liu, Yi ^a,b   Fu, Baochen ^a,b  

^a JINAN MILITARY GENERAL HOSPITAL   (China)

^b JINAN MATERNITY AND CHILD CARE HOSPITAL   (China)

Author keywords

Bladder cancer; Polymorphism; Toll like receptor 4

Indexed keywords

TLR4 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 4;

ADULT; AGED; ALLELE; ASIAN CONTINENTAL ANCESTRY GROUP; BIOSYNTHESIS; BLADDER TUMOR; CD8+ T LYMPHOCYTE; CHINA; FEMALE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HUMAN; IMMUNOLOGY; MALE; MIDDLE AGED; PATHOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CD8-POSITIVE T-LYMPHOCYTES; CHINA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; TOLL-LIKE RECEPTOR 4; URINARY BLADDER NEOPLASMS;

EID: 84936752103     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-2902-0     Document Type: Article

References (22)

1. Cheng L, Davison DD, Adams J, Lopez-Beltran A, Wang L, et al. Biomarkers in bladder cancer: translational and clinical implications. Crit Rev Oncol Hematol. 2014;89:73–111.
2. Gan C, Mostafid H, Khan MS, Lewis DJ. BCG immunotherapy for bladder cancer—the effects of substrain differences. Nat Rev Urol. 2013;10:580–8.
3. Rosser CJ, Urquidi V, Goodison S. Urinary biomarkers of bladder cancer: an update and future perspectives. Biomark Med. 2013;7:779–90.
4. Liu J, Buisman-Pijlman F, Hutchinson MR. Toll-like receptor 4: innate immune regulator of neuroimmune and neuroendocrine interactions in stress and major depressive disorder. Front Neurosci. 2014;8:309.
5. Bi J, Song S, Fang L, Wang D, Jing H, et al. Porcine reproductive and respiratory syndrome virus induces IL-1beta production depending on TLR4/MyD88 pathway and NLRP3 inflammasome in primary porcine alveolar macrophages. Mediat Inflamm. 2014;2014:403515.
6. Baliu-Pique M, Jusek G, Holzmann B. Neuroimmunological communication via CGRP promotes the development of a regulatory phenotype in TLR4-stimulated macrophages. Eur J Immunol. 2014. doi:10.1002/eji.201444553.
7. Agalave NM, Larsson M, Abdelmoaty S, Su J, Baharpoor A, et al. Spinal HMGB1 induces TLR4-mediated long-lasting hypersensitivity and glial activation and regulates pain-like behavior in experimental arthritis. Pain. 2014;155:1802–13.
8. Wang AC, Wu FX, Gao YS, Sheng XG. Toll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile in ovarian cancers. Oncol Lett. 2014;8:438–40.
9. Zhou Y, Yang J, Deng H, Xu H, Zhang J, et al. Respiratory syncytial virus infection modulates interleukin-8 production in respiratory epithelial cells through a transcription factor-activator protein-1 signaling pathway. Mol Med Rep. 2014;10:1443–7.
10. Takahashi T, Asano Y, Ichimura Y, Toyama T, Taniguchi T, et al. TLR4 knockout ameliorates tissue fibrosis in the murine models of systemic sclerosis. Arthritis Rheumatol. 2014. doi:10.1002/art.38901.
11. Mudaliar H, Pollock C, Ma J, Wu H, Chadban S, et al. The role of TLR2 and 4-mediated inflammatory pathways in endothelial cells exposed to high glucose. PLoS One. 2014;9:e108844.
12. Lewkowicz P, Lewkowicz N, Sasiak A, Tchorzewski H. Lipopolysaccharide-activated CD4+CD25+ T regulatory cells inhibit neutrophil function and promote their apoptosis and death. J Immunol. 2006;177:7155–63.
13. Zhai Y, Meng L, Gao F, Wang Y, Busuttil RW, et al. CD4+ T regulatory cell induction and function in transplant recipients after CD154 blockade is TLR4 independent. J Immunol. 2006;176:5988–94.
14. Frisancho-Kiss S, Davis SE, Nyland JF, Frisancho JA, Cihakova D, et al. Cutting edge: cross-regulation by TLR4 and T cell Ig mucin-3 determines sex differences in inflammatory heart disease. J Immunol. 2007;178:6710–4.
15. Morre SA, Murillo LS, Spaargaren J, Fennema HS, Pena AS. Role of the toll-like receptor 4 Asp299Gly polymorphism in susceptibility to Candida albicans infection. J Infect Dis. 2002;186:1377–9. author reply 1379.
16. Agundez JA, Garcia-Martin E, Devesa MJ, Carballo M, Martinez C, et al. Polymorphism of the TLR4 gene reduces the risk of hepatitis C virus-induced hepatocellular carcinoma. Oncology. 2012;82:35–40.
17. Akil I, Ozkinay F, Onay H, Canda E, Gumuser G, et al. Assessment of Toll-like receptor-4 gene polymorphism on pyelonephritis and renal scar. Int J Immunogenet. 2012;39:303–7.
18. Cheng CH, Lee YS, Tsau YK, Lin TY. Genetic polymorphisms and susceptibility to parenchymal renal infection among pediatric patients. Pediatr Infect Dis J. 2011;30:309–14.
19. Shen Y, Liu Y, Liu S, Zhang A. Toll-like receptor 4 gene polymorphisms and susceptibility to bladder cancer. Pathol Oncol Res. 2013;19:275–80.
20. Huang L, Yuan K, Liu J, Ren X, Dong X, et al. Polymorphisms of the TLR4 gene and risk of gastric cancer. Gene. 2014;537:46–50.
21. Oetting WS, Guan W, Schladt DP, Leduc RE, Jacobson PA, et al. Donor polymorphisms of toll-like receptor 4 associated with graft failure in liver transplant recipients. Liver Transpl. 2012;18:1399–405.
22. Nguyen TH, Mai NL, Le TP, Ha V, Nguyen TC, et al. Toll-like receptor 4 (TLR4) and typhoid fever in Vietnam. PLoS One. 2009;4:e4800.