Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome

PLoS Pathogens

Volumn 11, Issue 6, 2015, Pages

  Luo, Xi ^a   Wasilko, David J ^a   Liu, Yao ^b   Sun, Jiayi ^b   Wu, Xiaochun ^a   Luo, Zhao Qing ^b   Mao, Yuxin ^a  

^a School of Integrative Plant Sciences   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOSOME; PROTEIN SIDC; TERNARY COMPLEX FACTOR; UNCLASSIFIED DRUG; VIRULENCE FACTOR; BACTERIAL PROTEIN; SIDC PROTEIN, LEGIONELLA PNEUMOPHILA;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; FLUORESCENCE MICROSCOPY; IMMUNOFLUORESCENCE; LEGIONELLA PNEUMOPHILA; MOLECULAR CLONING; MOUSE; NONHUMAN; PHAGOSOME; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; WESTERN BLOTTING; ANIMAL; CELL LINE; CHEMISTRY; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC TRANSFECTION; METABOLISM; PROTEIN CONFORMATION; SITE DIRECTED MUTAGENESIS; UBIQUITINATION; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); LEGIONELLA; LEGIONELLA PNEUMOPHILA; MAMMALIA;

ANIMALS; BACTERIAL PROTEINS; BINDING SITES; CELL LINE; CRYSTALLOGRAPHY, X-RAY; FLUORESCENT ANTIBODY TECHNIQUE; LEGIONELLA PNEUMOPHILA; MUTAGENESIS, SITE-DIRECTED; PHAGOSOMES; PROTEIN CONFORMATION; TRANSFECTION; UBIQUITINATION; VIRULENCE FACTORS;

EID: 84936742425     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004965     Document Type: Article

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