Role of the N-terminal transmembrane domain in the endo-lysosomal targeting and function of the human ABCB6 protein

Biochemical Journal

Volumn 467, Issue 1, 2015, Pages 127-139

  Kiss, Katalin ^a   Kucsma, Nora ^a   Brozik, Anna ^a   Tusnady, Gabor E ^a   Bergam, Ptissam ^b,c,d   Van Niel, Guillaume ^b,c,d   Szakacs, Gergely ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b INSTITUT CURIE   (France)

^c INSTITUT CURIE   (France)

^d Cell and Tissue Imaging Facility   (France)

Author keywords

Adenosine 5 triphosphatase (ATPase); ATP binding cassette; ATP binding cassette (ABC) transporter; Lysosome; Subfamily B (ABCB) 6; Trafficking; Transmembrane domain

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER B6; ADENOSINE TRIPHOSPHATE; UNCLASSIFIED DRUG; ABCB6 PROTEIN, HUMAN; HYBRID PROTEIN; MUTANT PROTEIN; PEPTIDE FRAGMENT; SIGNAL PEPTIDE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIMERIZATION; ELECTRON MICROSCOPY; ENDOCYTOSIS; ENDOSOME; HYDROLYSIS; INTERNALIZATION; LYSOSOME; MULTIVESICULAR BODY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; AMINO ACID SUBSTITUTION; CHEMISTRY; GENETICS; HELA CELL LINE; HUMAN; K562 CELL LINE; METABOLISM; PROTEIN TERTIARY STRUCTURE; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

ADENOSINE TRIPHOSPHATE; AMINO ACID SUBSTITUTION; ATP-BINDING CASSETTE TRANSPORTERS; CELL MEMBRANE; DIMERIZATION; ENDOCYTOSIS; HELA CELLS; HUMANS; HYDROLYSIS; K562 CELLS; LYSOSOMES; MICROSCOPY, ELECTRON, TRANSMISSION; MULTIVESICULAR BODIES; MUTANT PROTEINS; PEPTIDE FRAGMENTS; PROTEIN FOLDING; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS;

EID: 84935897756     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20141085     Document Type: Article

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