Role of glycine-534 and glycine-1179 of human multidrug resistance protein (MDR1) in drug-mediated control of ATP hydrolysis

Biochemical Journal

Volumn 356, Issue 1, 2001, Pages 71-75

  Szakács, Gergely ^a   Özvegy, Csilla ^a   Bakos, Éva ^a   Sarkadi, Balázs ^a   Váradi, András ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

ABC signature; Allosteric effect; ATP binding cassette; Nucleotide trapping; P glycoprotein

Indexed keywords

ADENOSINETRIPHOSPHATE; CELL MEMBRANES; DRUG PRODUCTS; HYDROLYSIS;

MULTIDRUG RESISTANCE;

PROTEINS;

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; GLYCINE; MULTIDRUG RESISTANCE PROTEIN 1;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN HYDROLYSIS; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; ALLOSTERIC REGULATION; BIOLOGICAL TRANSPORT, ACTIVE; DRUG RESISTANCE, MULTIPLE; GLYCINE; HUMANS; HYDROLYSIS; MUTATION; P-GLYCOPROTEIN; RECOMBINANT PROTEINS; VARIATION (GENETICS);

ANIMALIA; SPODOPTERA; SPODOPTERA FRUGIPERDA;

EID: 0035874464     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3560071     Document Type: Article

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