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Volumn 59, Issue 7, 2015, Pages 3864-3869

Differential cytochrome P450 2D metabolism alters tafenoquine pharmacokinetics

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2D; PRIMAQUINE; TAFENOQUINE; AMINOQUINOLINE DERIVATIVE; ANTIMALARIAL AGENT; CYTOCHROME P450 2D6;

EID: 84935852828     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00343-15     Document Type: Article
Times cited : (39)

References (33)
  • 5
    • 33750512152 scopus 로고    scopus 로고
    • 8-Aminoquinolines: Future role as antiprotozoal drugs
    • Tekwani BL, Walker LA. 2006. 8-Aminoquinolines: future role as antiprotozoal drugs. Curr Opin Infect Dis 19:623-631. http://dx.doi.org/10.1097/QCO.0b013e328010b848.
    • (2006) Curr Opin Infect Dis , vol.19 , pp. 623-631
    • Tekwani, B.L.1    Walker, L.A.2
  • 6
    • 60549099364 scopus 로고    scopus 로고
    • Primaquine revisited six decades after its discovery
    • Vale N, Moreira R, Gomes P. 2009. Primaquine revisited six decades after its discovery. Eur J Med Chem 44:937-953. http://dx.doi.org/10.1016/j.ejmech.2008.08.011.
    • (2009) Eur J Med Chem , vol.44 , pp. 937-953
    • Vale, N.1    Moreira, R.2    Gomes, P.3
  • 9
    • 83255188683 scopus 로고    scopus 로고
    • Improving the therapeutic index of 8-aminoquinolines by the use of drug combinations: Review of the literature and proposal for future investigations
    • Myint HY, Berman J, Walker L, Pybus B, Melendez V, Baird JK, Ohrt C. 2011. Improving the therapeutic index of 8-aminoquinolines by the use of drug combinations: review of the literature and proposal for future investigations. Am J Trop Med Hyg 85:1010-1014. http://dx.doi.org/10.4269/ajtmh.2011.11-0498.
    • (2011) Am J Trop Med Hyg , vol.85 , pp. 1010-1014
    • Myint, H.Y.1    Berman, J.2    Walker, L.3    Pybus, B.4    Melendez, V.5    Baird, J.K.6    Ohrt, C.7
  • 12
    • 0026039418 scopus 로고
    • Simultaneous modeling of the pharmacokinetics and methemoglobin pharmacodynamics of an 8-aminoquinoline candidate antimalarial (WR 238605)
    • Brueckner RP, Fleckenstein L. 1991. Simultaneous modeling of the pharmacokinetics and methemoglobin pharmacodynamics of an 8-aminoquinoline candidate antimalarial (WR 238605). Pharm Res 8:1505-1510. http://dx.doi.org/10.1023/A:1015842316177.
    • (1991) Pharm Res , vol.8 , pp. 1505-1510
    • Brueckner, R.P.1    Fleckenstein, L.2
  • 13
    • 0031836936 scopus 로고    scopus 로고
    • First-time-in-humans safety and pharmacokinetics of WR 238605, a new antimalarial
    • Brueckner RP, Lasseter KC, Lin ET, Schuster BG. 1998. First-time-in-humans safety and pharmacokinetics of WR 238605, a new antimalarial. Am J Trop Med Hyg 58:645-649.
    • (1998) Am J Trop Med Hyg , vol.58 , pp. 645-649
    • Brueckner, R.P.1    Lasseter, K.C.2    Lin, E.T.3    Schuster, B.G.4
  • 14
    • 0035678895 scopus 로고    scopus 로고
    • Population pharmacokinetics of the new antimalarial agent tafenoquine in Thai soldiers
    • Edstein MD, Kocisko DA, Brewer TG, Walsh DS, Eamsila C, Charles BG. 2001. Population pharmacokinetics of the new antimalarial agent tafenoquine in Thai soldiers. Br J Clin Pharmacol 52:663-670. http://dx.doi.org/10.1046/j.1365-2125.2001.01482.x.
    • (2001) Br J Clin Pharmacol , vol.52 , pp. 663-670
    • Edstein, M.D.1    Kocisko, D.A.2    Brewer, T.G.3    Walsh, D.S.4    Eamsila, C.5    Charles, B.G.6
  • 15
    • 0034031718 scopus 로고    scopus 로고
    • Measurement of tafenoquine (WR 238605) in human plasma and venous and capillary blood by high-pressure liquid chromatography
    • Kocisko DA, Walsh DS, Eamsila C, Edstein MD. 2000. Measurement of tafenoquine (WR 238605) in human plasma and venous and capillary blood by high-pressure liquid chromatography. Ther Drug Monit 22: 184-189. http://dx.doi.org/10.1097/00007691-200004000-00008.
    • (2000) Ther Drug Monit , vol.22 , pp. 184-189
    • Kocisko, D.A.1    Walsh, D.S.2    Eamsila, C.3    Edstein, M.D.4
  • 16
    • 84899479595 scopus 로고    scopus 로고
    • Assessment of the prophylactic activity and pharmacokinetic profile of oral tafenoquine compared to primaquine for inhibition of liver stage malaria infections
    • Li Q, O'Neil M, Xie L, Caridha D, Zeng Q, Zhang J, Pybus B, Hickman M, Melendez V. 2014. Assessment of the prophylactic activity and pharmacokinetic profile of oral tafenoquine compared to primaquine for inhibition of liver stage malaria infections. Malar J 13:141. http://dx.doi.org/10.1186/1475-2875-13-141.
    • (2014) Malar J , vol.13 , pp. 141
    • Li, Q.1    O'Neil, M.2    Xie, L.3    Caridha, D.4    Zeng, Q.5    Zhang, J.6    Pybus, B.7    Hickman, M.8    Melendez, V.9
  • 18
    • 0035893187 scopus 로고    scopus 로고
    • A new primaquine analogue, tafenoquine (WR 238605), for prophylaxis against Plasmodium falciparum malaria
    • Shanks GD, Oloo AJ, Aleman GM, Ohrt C, Klotz FW, Braitman D, Horton J, Brueckner R. 2001. A new primaquine analogue, tafenoquine (WR 238605), for prophylaxis against Plasmodium falciparum malaria. Clin Infect Dis 33:1968-1974. http://dx.doi.org/10.1086/324081.
    • (2001) Clin Infect Dis , vol.33 , pp. 1968-1974
    • Shanks, G.D.1    Oloo, A.J.2    Aleman, G.M.3    Ohrt, C.4    Klotz, F.W.5    Braitman, D.6    Horton, J.7    Brueckner, R.8
  • 21
    • 84893180299 scopus 로고    scopus 로고
    • A retrospective analysis of the protective efficacy of tafenoquine and mefloquine as prophylactic anti-malarials in non-immune individuals during deployment to a malaria-endemic area
    • Dow GS, McCarthy WF, Reid M, Smith B, Tang D, Shanks GD. 2014. A retrospective analysis of the protective efficacy of tafenoquine and mefloquine as prophylactic anti-malarials in non-immune individuals during deployment to a malaria-endemic area. Malar J 13:49. http://dx.doi.org/10.1186/1475-2875-13-49.
    • (2014) Malar J , vol.13 , pp. 49
    • Dow, G.S.1    McCarthy, W.F.2    Reid, M.3    Smith, B.4    Tang, D.5    Shanks, G.D.6
  • 26
    • 84455162074 scopus 로고    scopus 로고
    • Modeling human cytochrome P450 2D6 metabolism and drug-drug interaction by a novel panel of knockout and humanized mouse lines
    • Scheer N, Kapelyukh Y, McEwan J, Beuger V, Stanley LA, Rode A, Wolf CR. 2012. Modeling human cytochrome P450 2D6 metabolism and drug-drug interaction by a novel panel of knockout and humanized mouse lines. Mol Pharmacol 81:63-72. http://dx.doi.org/10.1124/mol.111.075192.
    • (2012) Mol Pharmacol , vol.81 , pp. 63-72
    • Scheer, N.1    Kapelyukh, Y.2    McEwan, J.3    Beuger, V.4    Stanley, L.A.5    Rode, A.6    Wolf, C.R.7
  • 27
    • 33745245269 scopus 로고    scopus 로고
    • Expression, purification, and characterization of mouse CYP2d22
    • Yu AM, Haining RL. 2006. Expression, purification, and characterization of mouse CYP2d22. Drug Metab Dispos 34:1167-1174. http://dx.doi.org/10.1124/dmd.105.008870.
    • (2006) Drug Metab Dispos , vol.34 , pp. 1167-1174
    • Yu, A.M.1    Haining, R.L.2
  • 28
    • 1642292958 scopus 로고    scopus 로고
    • Primaquine-induced hemolytic anemia: Susceptibility of normal versus glutathione-depleted rat erythrocytes to 5-hydroxyprimaquine
    • Bowman ZS, Oatis JE, Jr, Whelan JL, Jollow DJ, McMillan DC. 2004. Primaquine-induced hemolytic anemia: susceptibility of normal versus glutathione-depleted rat erythrocytes to 5-hydroxyprimaquine. J Pharmacol Exp Ther 309:79-85. http://dx.doi.org/10.1124/jpet.103.062984.
    • (2004) J Pharmacol Exp Ther , vol.309 , pp. 79-85
    • Bowman, Z.S.1    Oatis, J.E.2    Whelan, J.L.3    Jollow, D.J.4    McMillan, D.C.5
  • 29
    • 0025013036 scopus 로고
    • ESR detection of free radical intermediates during autoxidation of 5-hydroxyprimaquine
    • Vasquez-Vivar J, Augusto O. 1990. ESR detection of free radical intermediates during autoxidation of 5-hydroxyprimaquine. Free Radic Res Commun 9:383-389. http://dx.doi.org/10.3109/10715769009145698.
    • (1990) Free Radic Res Commun , vol.9 , pp. 383-389
    • Vasquez-Vivar, J.1    Augusto, O.2
  • 30
    • 0026630568 scopus 로고
    • Hydroxylated metabolites of the antimalarial drug primaquine. Oxidation and redox cycling
    • Vasquez-Vivar J, Augusto O. 1992. Hydroxylated metabolites of the antimalarial drug primaquine. Oxidation and redox cycling. J Biol Chem 267:6848-6854.
    • (1992) J Biol Chem , vol.267 , pp. 6848-6854
    • Vasquez-Vivar, J.1    Augusto, O.2
  • 31
    • 0028047135 scopus 로고
    • Oxidative activity of primaquine metabolites on rat erythrocytes in vitro and in vivo
    • Vasquez-Vivar J, Augusto O. 1994. Oxidative activity of primaquine metabolites on rat erythrocytes in vitro and in vivo. Biochem Pharmacol 47:309-316. http://dx.doi.org/10.1016/0006-2952(94)90022-1.
    • (1994) Biochem Pharmacol , vol.47 , pp. 309-316
    • Vasquez-Vivar, J.1    Augusto, O.2
  • 32
    • 0028796504 scopus 로고
    • Metabolism of a candidate 8-aminoquinoline antimalarial agent, WR 238605, by rat liver microsomes
    • Idowu OR, Peggins JO, Brewer TG, Kelley C. 1995. Metabolism of a candidate 8-aminoquinoline antimalarial agent, WR 238605, by rat liver microsomes. Drug Metab Dispos 23:1-17.
    • (1995) Drug Metab Dispos , vol.23 , pp. 1-17
    • Idowu, O.R.1    Peggins, J.O.2    Brewer, T.G.3    Kelley, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.