High resolution imaging of intracellular oxygen concentration by phosphorescence lifetime

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Kurokawa, Hiromi ^a   Ito, Hidehiro ^a   Inoue, Mai ^a   Tabata, Kenji ^b   Sato, Yoshifumi ^c   Yamagata, Kazuya ^c   Kizaka Kondoh, Shinae ^a   Kadonosono, Tetsuya ^a   Yano, Shigenobu ^d   Inoue, Masahiro ^e   Kamachi, Toshiaki ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b DAIICHI UNIVERSITY OF PHARMACY   (Japan)

^c KUMAMOTO UNIVERSITY   (Japan)

^d NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^e OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

OXYGEN;

ANIMAL; CELL HYPOXIA; HUMAN; METABOLISM; MOLECULAR IMAGING; MOUSE; PHYSIOLOGY; PROCEDURES; TUMOR CELL LINE;

ANIMALS; CELL HYPOXIA; CELL LINE, TUMOR; HUMANS; MICE; MOLECULAR IMAGING; OXYGEN;

EID: 84935842023     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep10657     Document Type: Article

References (29)

1. Raymond, J. & Blankenship, R. E. Biosynthetic pathways, gene replacement and the antiquity of life. Geobiology. 2, 199-203 (2004).
2. Semenza, G. L. Life with oxygen. Science. 318, 62-64 (2007).
3. Wiederkehr, A. & Wollheim, C. B. Minireview: implication of mitochondria in insulin secretion and action. Endocrinology. 147, 2643-2649 (2006).
4. Zehetner, J. et al. PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells. Genes Dev. 22, 3135-3146 (2008).
5. Cannon, B. & Nedergaard, J. Brown adipose tissue: function and physiological signifcance. Physiol Rev. 84, 277-359 2003 (2004).
6. Braun, R. D., Lanzen, J. L., Snyder, S. A. & Dewhirst, M. W. Comparison of tumor and normal tissue oxygen tension measurements using OxyLite or microelectrodes in rodents. Am. J. Physiol. Heart Circ. Physiol. 280, H2533-2544 (2001).
7. Bobko, A. A. et al. Trityl-based EPR probe with enhanced sensitivity to oxygen. Free Radic. Biol. Med. 47, 654-658 (2009).
8. Arteel, G. E., Turman, R. G., Yates, J. M. & Raleigh, J. A. Evidence that hypoxia markers detect oxygen gradients in liver: pimonidazole and retrograde perfusion of rat liver. Br. J. Cancer. 72, 889-895 (1995).
9. Dmitriev, R. I. & Papkovsky, D. B. Optical probes and techniques for O2 measurement in live cells and tissue. Cell Mol. Life Sci. 69, 2025-2039 (2012).
10. Sakadzic, S. et al. Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue. Nat. Methods 7, 755-759 (2010).
11. Finikova, O. S. et al. Oxygen microscopy by two-photon-excited phosphorescence. Chemphyschem. 9, 1673-1679 (2008).
12. Okura, I. & Kamachi, T. in Handbook of Porphyrin Science: with Applications to Chemistry, Physics, Materials Science, Engineering, Biology and Medicine, Vol. 12 (eds Karl M. Kadish, Kevin M. Smith, & Roger Guilard) Ch. 297-348, (World Scientifc, 2011).
13. Zhang, S. et al. Phosphorescent light-emitting iridium complexes serve as a hypoxia-sensing probe for tumor imaging in living animals. Cancer Res. 70, 4490-4498 (2010).
14. Okura, I., Asakura, N., Kamachi, T. & Saito, T. Oxygen concentration imaging in a single living cell using phosphorescence lifetime of Pt-porphyrin. Journal of Porphyrins and Phthalocyanines. 11, 160-164 (2007).
15. Dmitriev, R. I., Zhdanov, A. V., Nolan, Y. M. & Papkovsky, D. B. Imaging of neurosphere oxygenation with phosphorescent probes. Biomaterials. 34, 9307-9317 (2013).
16. Rogers, G. W. et al. High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria. PLoS One. 6, e21746 (2011).
17. Miyazaki, J. et al. Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms. Endocrinology. 127, 126-132 (1990).
18. Soejima, A. et al. Mitochondrial DNA is required for regulation of glucose-stimulated insulin secretion in a mouse pancreatic beta cell line, MIN6. J. Biol. Chem. 271, 26194-26199 (1996).
19. Sato, Y. et al. Cellular hypoxia of pancreatic beta-cells due to high levels of oxygen consumption for insulin secretion in vitro. J. Biol. Chem. 286, 12524-12532 (2011).
20. Swedlow, J. R., Hu, K., Andrews, P. D., Roos, D. S. & Murray, J. M. Measuring tubulin content in Toxoplasma gondii: a comparison of laser-scanning confocal and wide-feld fuorescence microscopy. Proc. Natl. Acad. Sci. USA 99, 2014-2019 (2002).
21. Friedman, J. R. & Nunnari, J. Mitochondrial form and function. Nature. 505, 335-343 (2014).
22. Dmitriev, R. I., Zhdanov, A. V., Jasionek, G. & Papkovsky, D. B. Assessment of cellular oxygen gradients with a panel of phosphorescent oxygen-sensitive probes. Anal. Chem. 84, 2930-2938 (2012).
23. Spencer, J. A. et al. Direct measurement of local oxygen concentration in the bone marrow of live animals. Nature. 508, 269-273 (2014).
24. Arteel, G. E., Turman, R. G. & Raleigh, J. A. Reductive metabolism of the hypoxia marker pimonidazole is regulated by oxygen tension independent of the pyridine nucleotide redox state. Eur. J. Biochem. 253, 743-750 (1998).
25. Diers, A. R. et al. Mitochondrial bioenergetics of metastatic breast cancer cells in response to dynamic changes in oxygen tension: efects of HIF-1alpha. PLoS One. 8, e68348 (2013).
26. Klose, R. J. & Zhang, Y. Regulation of histone methylation by demethylimination and demethylation. Nat. Rev. Mol. Cell Biol. 8, 307-318 (2007).
27. Henquin, J. C., Nenquin, M., Stiernet, P. & Ahren, B. In vivo and in vitro glucose-induced biphasic insulin secretion in the mouse: pattern and role of cytoplasmic Ca2+ and amplifcation signals in beta-cells. Diabetes. 55, 441-451 (2006).
28. Gauuan, P. J. F. et al. Superoxide dismutase mimetics: synthesis and structure-activity relationship study of MnTBAP analogues. Bioorganic & Medicinal Chemistry. 10, 3013-3021 (2002).
29. Briñas, R. P., Troxler, T., Hochstrasser, R. M. & Vinogradov, S. A. Phosphorescent Oxygen Sensor with Dendritic Protection and Two-Photon Absorbing Antenna. Journal of the American Chemical Society. 127, 11851-11862 (2005).