MicroRNA-205 regulates ubiquitin specific peptidase 7 protein expression in hepatocellular carcinoma cells

Molecular Medicine Reports

Volumn 12, Issue 3, 2015, Pages 4652-4656

  Zhu, Liang ^a   Liu, Rong ^a   Zhang, Wei ^a   Qian, Sheng ^a   Wang, Jian Hua ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Hepatocellular carcinoma; MicroRNA 205; Proliferation; Ubiquitin specific peptidase 7

Indexed keywords

MICRORNA 205; PEPTIDES AND PROTEINS; PROTEIN P53; UBIQUITIN SPECIFIC PEPTIDASE 7; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; MICRORNA; MIRN205 MICRORNA, HUMAN; UBIQUITIN THIOLESTERASE; USP7 PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ARTICLE; CARCINOMA CELL; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL CARCINOMA; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; BINDING SITE; DOWN REGULATION; ENZYME REPRESSION; GENE EXPRESSION REGULATION; GENETICS; HEPG2 CELL LINE; LIVER TUMOR; METABOLISM; PHYSIOLOGY; RNA INTERFERENCE;

3' UNTRANSLATED REGIONS; BINDING SITES; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; DOWN-REGULATION; ENZYME REPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MICRORNAS; RNA INTERFERENCE; UBIQUITIN THIOLESTERASE;

EID: 84935416534     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3998     Document Type: Article

References (20)

1. Villanueva A, Hernandez-Gea V and Llovet JM: Medical therapies for hepatocellular carcinoma: a critical view of the evidence. Nat Rev Gastroenterol Hepatol 10:34-42, 2013.
2. Qing P, Han L, Bin L, Yan L and Ping WX: USP7 regulates the stability and function of HLTF through deubiquitination. J Cell Biochem 112:3856-3862, 2011.
3. Nicholson B and Suresh Kumar KG: The multifaceted roles of USP7: new therapeutic opportunities. Cell Biochem Biophys 60:61-68, 2011.
4. Lee JT and Gu W: The multiple levels of regulation by p53 ubiquitination. Cell Death Differ 17:86-92, 2010.
5. Colland F: The therapeutic potential of deubiquitinating enzyme inhibitors. Biochem Soc Trans 38:137-143, 2010.
6. Lee MH and Lozano G: Regulation of the p53-MDM2 pathway by 14-3-3 sigma and other proteins. Semin Cancer Biol 16:225-234, 2006.
7. Meulmeester E, Maurice MM, Boutell C, et al: Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2. Mol Cell 18:565-576, 2005.
8. Sun K and Lai EC: Adult-specific functions of animal microRNAs. Nat Rev Genet 14:535-548, 2013.
9. Ameres SL and Zamore PD: Diversifying microRNA sequence and function. Nat Rev Mol Cell Biol 14:475-488, 2013.
10. Liu Y, Xing R, Zhang X, et al: miR-375 targets the p53 gene to regulate cellular response to ionizing radiation and etoposide in gastric cancer cells. DNA Repair 12:741-750, 2013.
11. Nagano H, Tomimaru Y, Eguchi H, et al: MicroRNA-29a induces resistance to gemcitabine through the Wnt/beta-catenin signaling pathway in pancreatic cancer cells. Int J Oncol 43:1066-1072, 2013.
12. Zhang S, Shan C, Kong G, Du Y, Ye L and Zhang X: MicroRNA-520e suppresses growth of hepatoma cells by targeting the NF-kappaB-inducing kinase (NIK). Oncogene 31:3607-3620, 2012.
13. Giordano S and Columbano A: MicroRNAs: new tools for diagnosis, prognosis and therapy in hepatocellular carcinoma? Hepatology 57:840-847, 2013.
14. Wong CM, Kai AK, Tsang FH and Ng IO: Regulation of hepatocarcinogenesis by microRNAs. Front Biosci (Elite edi) 5:49-60, 2013.
15. Hou J, Lin L, Zhou W, et al: Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma. Cancer Cell 19:232-243, 2011.
16. Su N, Qiu H, Chen Y, Yang T, Yan Q and Wan X: miR-205 promotes tumor proliferation and invasion through targeting ESRRG in endometrial carcinoma. Oncology Reports 29:2297-2302, 2013.
17. Cai J, Fang L, Huang Y, et al: miR - 205 targets PTEN and PHLPP2 to augment AKT signaling and drive malignant phenotypes in non-small cell lung cancer. Cancer Res 73:5402-5415, 2013.
18. Wang N, Li Q, Feng NH, et al: miR-205 is frequently downregulated in prostate cancer and acts as a tumor suppressor by inhibiting tumor growth. Asian J Androl 15:735-741, 2013.
19. Yang Z, Huo S, Shan Y, et al: STAT3 repressed USP7 expression is crucial for colon cancer development. FEBS Lett 586:3013-3017, 2012.
20. Van Loosdregt J, Fleskens V, Fu J, et al: Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity. Immunity 39:259-271, 2013.