Dental follicle cells participate in tooth eruption via the RUNX2-MiR-31-SATB2 loop

Journal of Dental Research

Volumn 94, Issue 7, 2015, Pages 936-944

  Ge, J ^a   Guo, S ^a   Fu, Y ^a   Zhou, P ^a   Zhang, P ^a   Du, Y ^a   Li, M ^a   Cheng, J ^a   Jiang, H ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

bone remodeling; cleidocranial dysplasia; dental sac; matrix metalloproteinases; microRNA; osteoclasts

Indexed keywords

GELATINASE A; GELATINASE B; GUANINE; MATRIX ATTACHMENT REGION BINDING PROTEIN; MICRORNA; MIRN31 MICRORNA, HUMAN; MMP2 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; RUNX2 PROTEIN, HUMAN; SATB2 PROTEIN, HUMAN; THYMINE; TNFRSF11A PROTEIN, HUMAN; TNFRSF11B PROTEIN, HUMAN; TNFSF11 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RUNX2;

ADOLESCENT; ANIMAL; BONE DEVELOPMENT; BONE REMODELING; C57BL MOUSE; CELL CULTURE; CHILD; CLEIDOCRANIAL DYSPLASIA; COCULTURE; EXON; GENE SILENCING; GENETICS; HAPLOINSUFFICIENCY; HUMAN; MALE; MOUSE; MUTATION; NEWBORN; OSTEOCLAST; PATHOLOGY; PHYSIOLOGY; TOOTH ERUPTION; TOOTH SAC;

ADOLESCENT; ANIMALS; ANIMALS, NEWBORN; BONE REMODELING; CELLS, CULTURED; CHILD; CLEIDOCRANIAL DYSPLASIA; COCULTURE TECHNIQUES; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DENTAL SAC; EXONS; GENE KNOCKDOWN TECHNIQUES; GUANINE; HAPLOINSUFFICIENCY; HUMANS; MALE; MATRIX ATTACHMENT REGION BINDING PROTEINS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; MICRORNAS; MUTATION; OSTEOCLASTS; OSTEOGENESIS; OSTEOPROTEGERIN; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; THYMINE; TOOTH ERUPTION; TRANSCRIPTION FACTORS;

EID: 84935126536     PISSN: 00220345     EISSN: 15440591     Source Type: Journal    
DOI: 10.1177/0022034515578908     Document Type: Article

References (29)

1. Akech J, Wixted JJ, Bedard K, van der Deen M, Hussain S, Guise TA, van Wijnen AJ, Stein JL, Languino LR, Altieri DC, et al. 2010. Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions. Oncogene. 29(6):811-821.
2. Aprelikova O, Yu X, Palla J, Wei BR, John S, Yi M, Stephens R, Simpson RM, Risinger JI, Jazaeri A, et al. 2010. The role of miR-31 and its target gene SATB2 in cancer-associated fibroblasts. Cell Cycle. 9(21):4387-4398.
3. Baumert U, Golan I, Redlich M, Aknin JJ, Muessig D. 2005. Cleidocranial dysplasia: molecular genetic analysis and phenotypic-based description of a Middle European patient group. Am J Med Genet A. 139A(2):78-85.
4. Cao H, Wang J, Li X, Florez S, Huang Z, Venugopalan SR, Elangovan S, Skobe Z, Margolis HC, Martin JF, et al. 2010. MicroRNAs play a critical role in tooth development. J Dent Res. 89(8):779-784.
5. Cao JJ, Wronski TJ, Iwaniec U, Phleger L, Kurimoto P, Boudignon B, Halloran BP. 2005. Aging increases stromal/osteoblastic cell-induced osteoclastogenesis and alters the osteoclast precursor pool in the mouse. J Bone Miner Res. 20(9):1659-1668.
6. Chen P, Wei D, Xie B, Ni J, Xuan D, Zhang J. 2014. Effect and possible mechanism of network between microRNAs and RUNX2 gene on human dental follicle cells. J Cell Biochem. 115(2):340-348.
7. Deng Y, Wu S, Zhou H, Bi X, Wang Y, Hu Y, Gu P, Fan X. 2013. Effects of a miR-31, Runx2, and Satb2 regulatory loop on the osteogenic differentiation of bone mesenchymal stem cells. Stem Cells Dev. 22(16):2278-2286.
8. Deng Y, Zhou H, Zou D, Xie Q, Bi X, Gu P, Fan X. 2013. The role of miR-31-modified adipose tissue-derived stem cells in repairing rat critical-sized calvarial defects. Biomaterials. 34(28):6717-6728.
9. Dobreva G, Chahrour M, Dautzenberg M, Chirivella L, Kanzler B, Farinas I, Karsenty G, Grosschedl R. 2006. SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation. Cell. 125(5):971-986.
10. Dong W, Zhang P, Fu Y, Ge J, Cheng J, Yuan H, Jiang H. 2015. Roles of SATB2 in site-specific stemness, autophagy and senescence of bone marrow mesenchymal stem cells. J Cell Physiol. 230(3):680-690.
11. Dorotheou D, Gkantidis N, Karamolegkou M, Kalyvas D, Kiliaridis S, Kitraki E. 2013. Tooth eruption: altered gene expression in the dental follicle of patients with cleidocranial dysplasia. Orthod Craniofac Res. 16(1):20-27.
12. Enomoto H, Shiojiri S, Hoshi K, Furuichi T, Fukuyama R, Yoshida CA, Kanatani N, Nakamura R, Mizuno A, Zanma A, et al. 2003. Induction of osteoclast differentiation by Runx2 through receptor activator of nuclear factor-kappa B ligand (RANKL) and osteoprotegerin regulation and partial rescue of osteoclastogenesis in Runx2-/- mice by RANKL transgene. J Biol Chem. 278(26):23971-23977.
13. Huang XF, Zhao YB, Zhang FM, Han PY. 2009. Comparative study of gene expression during tooth eruption and orthodontic tooth movement in mice. Oral Dis. 15(8):573-579.
14. Ishibashi O, Niwa S, Kadoyama K, Inui T. 2006. MMP-9 antisense oligodeoxynucleotide exerts an inhibitory effect on osteoclastic bone resorption by suppressing cell migration. Life Sci. 79(17):1657-1660.
15. Jonason JH, Xiao G, Zhang M, Xing L, Chen D. 2009. Post-translational regulation of Runx2 in bone and cartilage. J Dent Res. 88(8):693-703.
16. Kim SG, Kim MH, Chae CH, Jung YK, Choi JY. 2008. Downregulation of matrix metalloproteinases in hyperplastic dental follicles results in abnormal tooth eruption. BMB Rep. 41(4):322-327.
17. Lee HS, Lee J, Kim SO, Song JS, Lee JH, Lee SI, Jung HS, Choi BJ. 2013. Comparative gene-expression analysis of the dental follicle and periodontal ligament in humans. PLoS One. 8(12):e84201.
18. Li B, Zhang Y, Wang Q, Dong Z, Shang L, Wu L, Wang X, Jin Y. 2014. Periodontal ligament stem cells modulate root resorption of human primary teeth via Runx2 regulating RANKL/OPG system. Stem Cells Dev. 23(20):2524-2534.
19. Marks SC Jr, Cahill DR. 1984. Experimental study in the dog of the non-active role of the tooth in the eruptive process. Arch Oral Biol. 29(4):311-322.
20. Mundlos S. 1999. Cleidocranial dysplasia: clinical and molecular genetics. J Med Genet. 36(3):177-182.
21. Mundlos S, Otto F, Mundlos C, Mulliken JB, Aylsworth AS, Albright S, Lindhout D, Cole WG, Henn W, Knoll JH, et al. 1997. Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia. Cell. 89(5):773-779.
22. Okada Y, Naka K, Kawamura K, Matsumoto T, Nakanishi I, Fujimoto N, Sato H, Seiki M. 1995. Localization of matrix metalloproteinase 9 (92-kilodalton gelatinase/type IV collagenase = gelatinase B) in osteoclasts: implications for bone resorption. Lab Invest. 72(3):311-322.
23. Omar NF, Gomes JR, Neves Jdos S, Salmon CR, Novaes PD. 2011. MT1-MMP expression in the odontogenic region of rat incisors undergoing interrupted eruption. J Mol Histol. 42(6):505-511.
24. Otto F, Kanegane H, Mundlos S. 2002. Mutations in the RUNX2 gene in patients with cleidocranial dysplasia. Hum Mutat. 19(3):209-216.
25. Popowics T, Boyd T, Hinderberger H. 2014. Eruptive and functional changes in periodontal ligament fibroblast orientation in CD44 wild-type vs. knockout mice. J Periodontal Res. 49(3):355-362.
26. Pratap J, Javed A, Languino LR, van Wijnen AJ, Stein JL, Stein GS, Lian JB. 2005. The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion. Mol Cell Biol. 25(19):8581-8591.
27. Swales C, Sabokbar A. 2014. Cellular and molecular mechanisms of bone damage and repair in inflammatory arthritis. Drug Discov Today. 19(8):1178-1185.
28. Tsubota M, Sasano Y, Takahashi I, Kagayama M, Shimauchi H. 2002. Expression of MMP-8 and MMP-13 mRNAs in rat periodontium during tooth eruption. J Dent Res. 81(10):673-678.
29. Wise GE. 2009. Cellular and molecular basis of tooth eruption. Orthod Craniofac Res. 12(2):67-73.