MMP-9 antisense oligodeoxynucleotide exerts an inhibitory effect on osteoclastic bone resorption by suppressing cell migration

Life Sciences

Volumn 79, Issue 17, 2006, Pages 1657-1660

  Ishibashi, Osamu ^a   Niwa, Satoru ^b   Kadoyama, Keiichi ^c   Inui, Takashi ^d  

^a NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^b NOVARTIS PHARMA K K   (Japan)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d Osaka Prefecture University   (Japan)

Author keywords

Antisense; Basement membrane; Bone resorption; Matrix metalloproteinase (MMP); Migration; MMP 9; Osteoclast; Pit volume

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; GELATINASE B; MATRIGEL; PROTEINASE; PROTEOGLYCAN;

ANIMAL CELL; ARTICLE; CELL MIGRATION; COATED PIT; CONCENTRATION RESPONSE; CONTROLLED STUDY; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RABBIT; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; BONE RESORPTION; CELL MOVEMENT; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; MATRIX METALLOPROTEINASE 9; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; OSTEOCLASTS; RABBITS;

EID: 33748416303     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2006.05.024     Document Type: Article

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