Simultaneous determination of leucine, isoleucine and valine in Beagle dog plasma by HPLC-MS/MS and its application to a pharmacokinetic study

Journal of Pharmaceutical and Biomedical Analysis

Volumn 114, Issue , 2015, Pages 426-432

  Wang, Ting ^a   Xie, Huiru ^a   Chen, Xu ^a   Jiang, Xuehua ^a   Wang, Ling ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

BCAAs; Beagle dog plasma; Gender; HPLC MS MS; Pharmacokinetics

Indexed keywords

HOMOARGININE; ISOLEUCINE; LEUCINE; VALINE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BEAGLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DOSE COMPARISON; DRUG MEGADOSE; ELIMINATION HALF-LIFE; ELIMINATION RATE CONSTANT; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LOW DRUG DOSE; MALE; MAXIMUM PLASMA CONCENTRATION; MEASUREMENT ACCURACY; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; STANDARD; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; ANIMAL; BLOOD; CALIBRATION; CHEMISTRY; DOG; ORAL DRUG ADMINISTRATION; PLASMA; PROCEDURES; QUALITY CONTROL; VALIDATION STUDY;

ADMINISTRATION, ORAL; ANIMALS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOGS; FEMALE; ISOLEUCINE; LEUCINE; MALE; PLASMA; QUALITY CONTROL; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY; VALINE;

EID: 84934997844     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2015.06.015     Document Type: Article

References (23)

1. Platell C., Kong S.E., McCauley R., Hall J.C. Branched-chain amino acids. J. Gastroenterol. Hepatol. 2000, 15:706-717.
2. De Bandt J.P., Cynober L. Therapeutic use of branched-chain amino acids in burn trauma, and sepsis. J. Nutr. 2006, 136:308S-313S.
3. Metcalfe E.L., Avenell A., Fraser A. Branched-chain amino acid supplementation in adults with cirrhosis and porto-systemic encephalopathy: systematic review. Clin. Nutr. 2014, 33:958-965.
4. Matsumura T., Morinaga Y., Fujitani S., Takehana K., Nishitani S., Sonaka I. Oral administration of branched-chain amino acids activates the mTOR signal in cirrhotic rat liver. Hepatol. Res. 2005, 33:27-32.
5. Nishitani S., Horie M., Ishizaki S., Yano H. Branched chain amino acid suppresses hepatocellular cancer stem cells through the activation of mammalian target of rapamycin. PLoS One 2013, 8:e82346.
6. Armon C. Sports and trauma in amyotrophic lateral sclerosis revisited. J. Neurol. Sci. 2007, 262:45-53.
7. Pieri M., Carunchio I., Curcio L., Mercuri N.B., Zona C. Increased persistent sodium current determines cortical hyperexcitability in a genetic model of amyotrophic lateral sclerosis. Exp. Neurol. 2009, 215:368-379.
8. Abel E.L. Football increases the risk for Lou Gehrig's disease, amyotrophic lateral sclerosis. Percept. Mot. Skills 2007, 104:1251-1254.
9. Millikan W.J., Henderson J.M., Galloway J.R., Warren W.D., Matthews D.E., McGhee A., Kutner M.H. In vivo measurement of leucine metabolism with stable isotopes in normal subjects and in those with cirrhosis fed conventional and branched-chain amino acid-enriched diets. Surgery 1985, 98:405-413.
10. Marchesini G., Bianchi G.P., Vilstrup H., Checchia G.A., Patrono D., Zoli M. Plasma clearances of branched-chain amino acids in control subjects and in patients with cirrhosis. J. Hepatol. 1987, 4:108-117.
11. Herman M.A., She P., Peroni O.D., Lynch C.J., Kahn B.B. Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels. J. Biol. Chem. 2010, 285:11348-11356.
12. Alodaib A., Carpenter K., Wiley V., Sim K., Christodoulou J., Wilcken B. An improved ultra performance liquid chromatography-tandem mass spectrometry method for the determination of alloisoleucine and branched chain amino acids in dried blood samples. Ann. Clin. Biochem. 2011, 48:468-470.
13. Sowell J., Pollard L., Wood T. Quantification of branched-chain amino acids in blood spots and plasma by liquid chromatography tandem mass spectrometry for the diagnosis of maple syrup urine disease. J. Sep. Sci. 2011, 34:631-639.
14. Oglesbee D., Sanders K.A., Lacey J.M., Magera M.J., Casetta B., Strauss K.A., Tortorelli S., Rinaldo P., Matern D. Second-tier test for quantification of alloisoleucine and branched-chain amino acids in dried blood spots to improve newborn screening for maple syrup urine disease (MSUD). Am. Assoc. Clin. Chem. 2008, 54:542-549.
15. Yang R., Dong J., Guo H., Li H., Wang S., Zhao H., Zhou W., Yu S., Wang M., Chen W. Rapid and precise measurement of serum branched-chain and aromatic amino acids by isotope dilution liquid chromatography tandem mass spectrometry. PLoS One 2013, 8:e81144.
16. Johnson D.W. Free amino acid quantification by LC-MS/MS using derivatization generated isotope-labelled standards. J. Chrom. B 2011, 879:1345-1352.
17. Contrusciere V., Paradisi S., Matteucci A., Malchiodi-Albedi F. Branched-chain amino acids induce neurotoxicity in rat cortical cultures. Neurotox. Res. 2010, 17:392-398.
18. Carunchio I., Curcio L., Pieri M., Pica F., Caioli S., Viscomi M.T., Molinari M., Canua N., Bernardi G., Zona C. Increased levels of p70S6 phosphorylation in the G93A mouse model of Amyotrophic Lateral Sclerosis and in valine-exposed cortical neurons in culture. Exp. Neurol. 2010, 226:218-230.
19. Fouré A., Nosaka K., Gastaldi M., Mattei J.P., Boudinet H., Guye M., Vilmena C., Fura Y.L., Bendahan D., Gondin J. Effects of branched-chain amino acids supplementation on both plasma amino acids concentration and muscle energetics changes resulting from muscle damage: a randomized placebo controlled trial clinical nutrition. Clin. Nutr. 2015, 10.1016/j.clnu.2015.03.014.
20. Shimomura Y., Inaguma A., Watanabe S., Yamamoto Y., Muramatsu Y., Bajotto G., Sato J., Shimomura N., Kobayashi H., Mawatari K. Branched-chain amino acid supplementation before squat exercise and delayed-onset muscle soreness. Int. J. Sport Nutr. 2010, 20:236-244.
21. Bröer S. Amino acid transport across mammalian intestinal and renal epithelia. Physiol. Rev. 2008, 88:249-286.
22. Morales A., Arce N., Cota M., Buenabad L., Avelar E., Htoo J.K., Cervantes M. Effect of dietary excess of branched-chain amino acids on performance and serum concentrations of amino acids in growing pigs. J. Anim. Physiol. An. Nutr. 2015, 10.1111/jpn.12327.
23. Majumder M., Yaman I., Gaccioli F., Zeenko V.V., Wang C., Caprara M.G., Venema R.C., Komar A.A., Snider M.D., Hatzoglou M. The hnRNA-binding proteins hnRNP L and PTB are required for efficient translation of the Cat-1 arginine/lysine transporter mRNA during amino acid starvation. Mol. Cell. Biol. 2009, 29:2899-2912.