Effect of dietary excess of branched-chain amino acids on performance and serum concentrations of amino acids in growing pigs

Journal of Animal Physiology and Animal Nutrition

Volumn 100, Issue 1, 2016, Pages 39-45

  Morales, A ^a   Arce, N ^a   Cota, M ^a   Buenabad, L ^a   Avelar, E ^a   Htoo, J K ^b   Cervantes, M ^a  

^a UNIVERSIDAD AUTÓNOMA DE BAJA CALIFORNIA   (Mexico)

^b EVONIK INDUSTRIES AG   (Germany)

Author keywords

Amino acid serum concentration; Branched chain amino acids; Excess Leu; Performance; Pigs

Indexed keywords

AMINO ACID;

ANALYSIS; ANIMAL; ANIMAL FOOD; BLOOD; CONTROLLED STUDY; DIET; DOSE RESPONSE; FEMALE; MALE; PIG; RANDOMIZED CONTROLLED TRIAL; VETERINARY;

AMINO ACIDS; ANIMAL FEED; ANIMAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; ANIMALS; DIET; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MALE; SWINE;

EID: 84953635522     PISSN: 09312439     EISSN: 14390396     Source Type: Journal    
DOI: 10.1111/jpn.12327     Document Type: Article

References (24)

1. Adibi, S. A.; Mercer, D. W., 1973: Protein digestion in human intestine as reflected in luminal, mucosal, and plasma amino acid concentrations after meals. The Journal of Clinical Investigation 52, 1586-1594.
2. Barea, R.; Brossard, L.; Le Floc'h, N.; Primont, Y.; Melchior, D.; van Milgen, J., 2009: The standardized ileal digestible valine to lysine requirement ratio is at least 70% in post-weaning piglets. Journal of Animal Science 87, 935-947.
3. Block, K. P., 1989: Interactions among leucine, isoleucine, and valine with special reference to the branched-chain amino acid antagonism. In: M. Friedman (ed.), Absorption and Utilization of Amino Acids, Vol. 1. CRC Press, Boca Raton, FL, USA, pp. 229-244.
4. Block, K. P.; Harper, A. E., 1984: Valine metabolism in vivo: effects of high dietary levels of leucine and isoleucine. Metabolism 33, 559-566.
5. Broer, S., 2008: Amino acid transport across mammalian intestinal and renal epithelia. Physiological Reviews 88, 249-286.
6. Cervantes-Ramírez, M.; Méndez-Trujillo, V.; Araiza-Piña, B. A.; Barrera-Silva, M. A.; González-Mendoza, D.; Morales-Trejo, A., 2013: Supplemental leucine and isoleucine affect expression of cationic amino acid transporters and myosin, serum concentration of amino acids, and growth performance of pigs. Genetics and Molecular Research 12, 115-126.
7. Commission Directive, 2000: Establishing community methods for the determination of vitamin A, vitamin E and tryptophan, annex part C. Determination of Tryptophan. Official Journal 174, 45-50.
8. Edmonds, M. S.; Baker, D. H., 1987: Amino acid excesses for young pigs: effects of excess Methionine, tryptophan, threonine or leucine. Journal of Animal Science 64, 1664-1671.
9. García-Villalobos, H.; Morales-Trejo, A.; Araiza-Piña, B. A.; Htoo, J. K.; Cervantes-Ramírez, M., 2012: Effects of dietary protein and amino acid levels on the expression of selected cationic amino acid transporters and serum amino acid concentration in growing pigs. Archives of Animal Nutrition 6, 257-270.
10. Gatnau, R.; Zimmerman, D. R.; Nissen, S. L.; Wannemuehlert, M.; Ewan, R. C., 1995: Effects of excess dietary leucine and leucine catabolites on growth and immune responses in weanling pigs. Journal of Animal Science 73, 159-165.
11. Langer, S.; Fuller, M. F., 2000: Interactions among the branched chain amino acids and their effects on methionine utilization in growing pigs: effects on nitrogen retention and amino acid utilization. British Journal of Nutrition 83, 43-48.
12. Langer, S.; Scislowski, P. W. D.; Brown, D. S.; Dewey, P.; Fuller, M. F., 2000: Interactions among the branched-chain amino acids and their effects on methionine utilization in growing pigs: effects on plasma amino- and keto-acid concentrations and branched-chain keto-acid dehydrogenase activity. British Journal of Nutrition 83, 49-58.
13. Llames, C. R.; Fontaine, J., 1994: Determination of amino acids in feeds: collaborative study. Journal - Association of Official Analytical Chemists 77, 1362-1402.
14. Mahan, D. C.; Shields, R. G. Jr, 1998: Essential and nonessential amino acid composition of pigs from birth to 145 kilograms of body weight, and comparison to other studies. Journal of Animal Science 76, 513-521.
15. Majumder, M.; Yaman, I.; Gaccioli, F.; Zeenko, V. V.; Wang, C.; Caprara, M. G.; Venema, R. C.; Komar, A. A.; Snider, M. D.; Hatzoglou, M., 2009: The hnRNA-binding proteins hnRNP L and PTB are required for efficient translation of the Cat-1 arginine/lysine transporter mRNA during amino acid starvation. Molecular and Cellular Biology 29, 2899-2912.
16. Norma Oficial Mexicana (NOM-062-ZOO-1999), 2001: Especificaciones técnicas para la producción, cuidado y uso de los animales de laboratorio. In: M. L. I. Ochoa (ed.). Diario Oficial de la Federación, México (DF), México, pp. 1-58.
17. NRC, 1998: Nutrient Requirements of Swine, 10th revised edn. National Academy Press, Washington, DC, USA.
18. NRC, 2012: Nutrient Requirements of Swine, 11th revised edn. National Academy Press, Washington, DC, USA.
19. Pineda, M.; Wagner, C. A.; Broer, A.; Stehberger, P. A.; Kaltenbach, S.; Gelpi, J. L.; Martin Del Rio, R.; Zorzano, A.; Palacin, A.; Lang, A.; Broer, S., 2004: Cystinuria-specific rBAT(R365W) mutation reveals two translocation pathways in the amino acid transporter rBATb0, AT. The Biochemical Journal 377, 665-674.
20. 0AT-cluster and their tissue distribution in Mus musculus. American Journal of Physiology. Renal Physiology 290, F376-F383.
21. Stein, H. H.; Kim, S. W.; Nielsen, T. T.; Easter, R. A., 2001: Standardized ileal protein and amino acid digestibility by growing pigs and sows. Journal of Animal Science 79, 2113-2122.
22. Wilson, G. J.; Layman, D. K.; Moulton, C. J.; Norton, L. E.; Anthony, T. G.; Proud, C. G.; Rupassara, S. I.; Garlick, P. J., 2011: Leucine or carbohydrate supplementation reduces AMPK and eEF2 phosphorylation and extends postprandial muscle protein synthesis in rats. American Journal of Physiology. Endocrinology and Metabolism 301, E1236-E1242.
23. Wiltafsky, M. K.; Pfaff, M. W.; Xaver, F., 2010: The effects of branched-chain amino acid interactions on growth performance, blood metabolites, enzyme kinetics and transcriptomics in weaned pigs. British Journal of Nutrition 103, 964-976.
24. Yen, J. T.; Kerr, B. J.; Easter, R. A.; Parkhurst, A. M., 2004: Difference in rates of net portal absorption between crystalline and protein-bound lysine and threonine in growing pigs fed once daily. Journal of Animal Science 82, 1079-1090.