Construction of an Aptamer-SiRNA Chimera-Modified Tissue-Engineered Blood Vessel for Cell-Type-Specific Capture and Delivery

ACS Nano

Volumn 9, Issue 6, 2015, Pages 6069-6076

  Chen, Wen ^a   Zeng, Wen ^a   Sun, Jiansen ^a   Yang, Mingcan ^a   Li, Li ^a   Zhou, Jingting ^a   Wu, Yangxiao ^a   Sun, Jun ^a   Liu, Ge ^a   Tang, Rui ^a   Tan, Ju ^a   Zhu, Chuhong ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

adenosine kinase; aptamer siRNA chimeras; CD133; diabetes mellitus; tissue engineered blood vessels

Indexed keywords

BLOOD VESSEL PROSTHESES; CELLS; CYTOLOGY; ENDOTHELIAL CELLS; ENZYMES; MOLECULAR BIOLOGY; RNA; SHEAR STRESS; TISSUE;

ADENOSINE KINASE; APTAMERS; CD133; DIABETES MELLITUS; TISSUE ENGINEERED BLOOD VESSELS;

BLOOD VESSELS;

ADENOSINE KINASE; APTAMER; CD133 ANTIGEN; GLYCOPROTEIN; LEUKOCYTE ANTIGEN; PEPTIDE; SMALL INTERFERING RNA; STREPTOZOCIN;

ANIMAL; BLOOD VESSEL; CELL CULTURE; CHEMICALLY INDUCED; CHEMISTRY; CHIMERA; CYTOLOGY; DIABETES MELLITUS, EXPERIMENTAL; ENDOTHELIAL PROGENITOR CELL; HUMAN; METABOLISM; NORMAL HUMAN; RAT; TISSUE ENGINEERING; WISTAR RAT;

ADENOSINE KINASE; ANIMALS; ANTIGENS, CD; APTAMERS, NUCLEOTIDE; BLOOD VESSELS; CELLS, CULTURED; CHIMERA; DIABETES MELLITUS, EXPERIMENTAL; ENDOTHELIAL PROGENITOR CELLS; GLYCOPROTEINS; HEALTHY VOLUNTEERS; HUMANS; PEPTIDES; RATS; RATS, WISTAR; RNA, SMALL INTERFERING; STREPTOZOCIN; TISSUE ENGINEERING;

EID: 84934955874     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b01203     Document Type: Article

References (24)

1. Guariguata, L. By the Numbers: New Estimates from the IDF Diabetes Atlas Update for 2012 Diabetes Res. Clin. Pract. 2012, 98, 524-525
2. Haraguchi, Y.; Shimizu, T.; Yamato, M.; Okano, T. Concise Review: Cell Therapy and Tissue Engineering for Cardiovascular Disease Stem Cells Transl. Med. 2012, 1, 136-141
3. Dahl, S. L.; Kypson, A. P.; Lawson, J. H.; Blum, J. L.; Strader, J. T.; Li, Y.; Manson, R. J.; Tente, W. E.; DiBernardo, L.; Hensley, M. T. et al. Readily Available Tissue-Engineered Vascular Grafts Sci. Transl. Med. 2011, 3, 68ra9
4. McAllister, T. N.; Maruszewski, M.; Garrido, S. A.; Wystrychowski, W.; Dusserre, N.; Marini, A.; Zagalski, K.; Fiorillo, A.; Avila, H.; Manglano, X. et al. Effectiveness of Haemodialysis Access with an Autologous Tissue-Engineered Vascular Graft: a Multicentre Cohort Study Lancet 2009, 373, 1440-1446
5. Wystrychowski, W.; Cierpka, L.; Zagalski, K.; Garrido, S.; Dusserre, N.; Radochonski, S.; McAllister, T. N.; L'Heureux, N. Case Study: First Implantation of a Frozen, Devitalized Tissue-Engineered Vascular Graft for Urgent Hemodialysis Access J. Vasc. Access 2011, 12, 67-70
6. Dahl, S. L. M.; Blum, J. L.; Niklason, L. E. Bioengineered Vascular Grafts: Can We Make Them Off-the-Shelf? Trends Cardiovasc. Med. 2011, 21, 83-89
7. O'Callaghan, T. Options for Off-the-Shelf Blood Vessels Expand. Nat. News 2011, DOI: 10.1038/news.2011.66.
8. Asahara, T.; Murohara, T.; Sullivan, A.; Silver, M.; van der Zee, R.; Li, T.; Witzenbichler, B.; Schatteman, G.; Isner, J. M. Isolation of Putative Progenitor Endothelial Cells for Angiogenesis Science 1997, 275, 964-967
9. Zeng, W.; Wen, C.; Wu, Y. X.; Li, L.; Zhou, Z. H.; Mi, J. H.; Chen, W.; Yang, M. C.; Hou, C. L.; Sun, J. S. et al. The Use of BDNF to Enhance the Patency Rate of Small-Diameter Tissue-Engineered Blood Vessels through Stem Cell Homing Mechanisms Biomaterials 2012, 33, 473-484
10. Rotmans, J. I.; Heyligers, J. M.; Verhagen, H. J.; Velema, E.; Nagtegaal, M. M.; de Kleijn, D. P.; de Groot, F. G.; Stroes, E. S.; Pasterkamp, G. In Vivo Cell Seeding with Anti-CD34 Antibodies Successfully Accelerates Endothelialization but Stimulates Intimal Hyperplasia in Porcine Arteriovenous Expanded Polytetrafluoroethylene Grafts Circulation 2005, 112, 12-18
11. Van der Heiden, K.; Gijsen, F. J.; Narracott, A.; Hsiao, S.; Halliday, I.; Gunn, J.; Wentzel, J. J.; Evans, P. C. The Effects of Stenting on Shear Stress: Relevance to Endothelial Injury and Repair Cardiovasc. Res. 2013, 99, 269-275
12. Duckers, H. J.; Silber, S.; de Winter, R.; den Heijer, P.; Rensing, B.; Rau, M.; Mudra, H.; Benit, E.; Verheye, S.; Wijns, W. et al. Circulating Endothelial Progenitor Cells Predict Angiographic and Intravascular Ultrasound Outcome Following Percutaneous Coronary Interventions in the HEALING-II Trial: Evaluation of an Endothelial Progenitor Cell Capturing Stent Eurointervention 2007, 3, 67-75
13. Fredholm, B. B.; AP, I. J.; Jacobson, K. A.; Linden, J.; Muller, C. E. International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors-an Update Pharmacol Rev. 2011, 63, 1-34
14. Shen, H. Y.; Lusardi, T. A.; Williams-Karnesky, R. L.; Lan, J. Q.; Poulsen, D. J.; Boison, D. Adenosine Kinase Determines the Degree of Brain Injury after Ischemic Stroke in Mice J. Cereb. Blood Flow Metab. 2011, 31, 1648-1659
15. Boison, D. Adenosine Kinase: Exploitation for Therapeutic Gain Pharmacol. Rev. 2013, 65, 906-943
16. Chen, W.; Zeng, W.; Wu, Y.; Wen, C.; Li, L.; Liu, G.; Shen, L.; Yang, M.; Tan, J.; Zhu, C. The Construction of Tissue-Engineered Blood Vessels Crosslinked with Adenosine-Loaded Chitosan/beta-Cyclodextrin Nanoparticles Using a Layer-by-Layer Assembly Method Adv. Healthc. Mater. 2014, 3, 1776-1781
17. Barcelos, L. S.; Duplaa, C.; Krankel, N.; Graiani, G.; Invernici, G.; Katare, R.; Siragusa, M.; Meloni, M.; Campesi, I.; Monica, M. et al. Human CD133+ Progenitor Cells Promote the Healing of Diabetic Ischemic Ulcers by Paracrine Stimulation of Angiogenesis and Activation of Wnt Signaling Circ. Res. 2009, 104, 1095-1102
18. Molenaar, C.; Marras, S. A.; Slats, J. C.; Truffert, J. C.; Lemaitre, M.; Raap, A. K.; Dirks, R. W.; Tanke, H. J. Linear 2′ O-Methyl RNA Probes for the Visualization of RNA in Living Cells Nucleic Acids Res. 2001, 29, E89-E89
19. Yin, Y.; Zhao, X.; Fang, Y.; Yu, S.; Zhao, J.; Song, M.; Huang, L. SDF-1alpha Involved in Mobilization and Recruitment of Endothelial Progenitor Cells after Arterial Injury in Mice Cardiovasc. Pathol. 2010, 19, 218-227
20. Sbaa, E.; Dewever, J.; Martinive, P.; Bouzin, C.; Frerart, F.; Balligand, J. L.; Dessy, C.; Feron, O. Caveolin Plays a Central Role in Endothelial Progenitor Cell Mobilization and Homing in SDF-1-Driven Postischemic Vasculogenesis Circ. Res. 2006, 98, 1219-1227
21. McNamara, J. O., 2nd; Andrechek, E. R.; Wang, Y.; Viles, K. D.; Rempel, R. E.; Gilboa, E.; Sullenger, B. A.; Giangrande, P. H. Cell Type-Specific Delivery of SiRNAs with Aptamer-SiRNA Chimeras Nat. Biotechnol. 2006, 24, 1005-1015
22. Dassie, J. P.; Liu, X. Y.; Thomas, G. S.; Whitaker, R. M.; Thiel, K. W.; Stockdale, K. R.; Meyerholz, D. K.; McCaffrey, A. P.; McNamara, J. O., 2nd; Giangrande, P. H. Systemic Administration of Optimized Aptamer-SiRNA Chimeras Promotes Regression of PSMA-Expressing Tumors Nat. Biotechnol. 2009, 27, 839-849
23. Shigdar, S.; Qiao, L.; Zhou, S. F.; Xiang, D.; Wang, T.; Li, Y.; Lim, L. Y.; Kong, L.; Li, L.; Duan, W. RNA Aptamers Targeting Cancer Stem Cell Marker CD133 Cancer Lett. 2013, 330, 84-95
24. Fitts, M. K.; Pike, D. B.; Anderson, K.; Shiu, Y. T. Hemodynamic Shear Stress and Endothelial Dysfunction in Hemodialysis Access Open Urol. Nephrol. J. 2014, 7, 33-44