3D spheroid cultures improve the metabolic gene expression profiles of HepaRG cells

Bioscience Reports

Volumn 35, Issue 3, 2015, Pages 1-7

  Takahashi, Yu ^a   Hori, Yuji ^a   Yamamoto, Tomohisa ^a   Urashima, Toshiki ^a   Ohara, Yasunori ^a   Tanaka, Hideo ^a  

^a JAPAN TOBACCO INC   (Japan)

Author keywords

3D culture; Gene expression; Hanging drop; HepaRG cells; HepG2 cells

Indexed keywords

ALBUMIN; APOLIPOPROTEIN B; CYTOCHROME P450; GLUCOSE; LIPID; LOW DENSITY LIPOPROTEIN; MESSENGER RNA; VERY LOW DENSITY LIPOPROTEIN; ALBUMINOID; CYTOCHROME P450 INDUCER; OMEPRAZOLE; PHENOBARBITAL; RIFAMPICIN; TRANSCRIPTOME;

ARTICLE; CELL ASSAY; CELL CULTURE; CELL LEVEL; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GLUCOSE METABOLISM; HEPATOCELLULAR CARCINOMA CELL LINE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; LIPID METABOLISM; METABOLIC GENE; MOLECULAR DYNAMICS; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN SECRETION; THREE DIMENSIONAL IMAGING; CELL CULTURE TECHNIQUE; DEVICES; DRUG EFFECTS; GENETICS; HEP-G2 CELL LINE; LIVER; METABOLISM; MULTICELLULAR SPHEROID; PHYSIOLOGY; PROCEDURES; SECRETION (PROCESS);

ALBUMINS; APOLIPOPROTEINS B; CELL CULTURE TECHNIQUES; CYTOCHROME P-450 ENZYME INDUCERS; CYTOCHROME P-450 ENZYME SYSTEM; GLUCOSE; HEP G2 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; LIPID METABOLISM; LIPOPROTEINS, LDL; LIVER; OMEPRAZOLE; PHENOBARBITAL; RIFAMPIN; SPHEROIDS, CELLULAR; TRANSCRIPTOME;

EID: 84934934954     PISSN: 01448463     EISSN: 15734935     Source Type: Journal    
DOI: 10.1042/BSR20150034     Document Type: Article

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