Vector systems for prenatal gene therapy: Principles of adeno-associated virus vector design and production

Methods in Molecular Biology

Volumn 891, Issue , 2012, Pages 109-131

  Binny, Christopher J ^a   Nathwani, Amit C ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

AAV pseudotype targeting; AAV serotype tropism; Adeno associated virus; Affinity chromatography; Concentration; Directed evolution of AAV vector; Preparation; Proteosomal degradation; Purification of AAV; Rational AAV vector design; Recombinant AAV; Species and sex dependence of AAV transduction; Titration; Transcapsidation; Transfection

Indexed keywords

ACETIC ACID; METHANOL; PARVOVIRUS VECTOR; PLASMID VECTOR; WATER;

ACIDIFICATION; APOPTOSIS; ARTICLE; CENTRIFUGATION; CHROMOSOME 19Q; DNA DEGRADATION; DNA FLANKING REGION; ENDOSOME; GENE EXPRESSION; GENE INSERTION; GENE VECTOR; HUMAN; INVERTED TERMINAL REPEAT; ION EXCHANGE CHROMATOGRAPHY; NONHUMAN; PH; POLYMERASE CHAIN REACTION; PRENATAL CARE; PRIORITY JOURNAL; VIRAL GENE THERAPY; VIRUS PURIFICATION; VIRUS REPLICATION;

EID: 84934437651     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-873-3_6     Document Type: Article

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