Tropomyosin: Regulator of actin filaments

Advances in Experimental Medicine and Biology

Volumn 592, Issue , 2007, Pages 87-97

  Hitchcock DeGregori, Sarah E ^a   Greenfield, Norma J ^a   Singh, Abhishek ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN BINDING PROTEIN; TROPOMYOSIN;

ACTIN FILAMENT; AMINO ACID SEQUENCE; CARBOXY TERMINAL SEQUENCE; CONFERENCE PAPER; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; X RAY DIFFRACTION;

EID: 84934436907     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-4-431-38453-3_9     Document Type: Conference Paper

References (66)

1. Bamburg, J. R., 1999, Proteins of the ADF/cofilin family: essential regulators of actin dynamics. Annu. Rev. Cell Dev. Biol. 15:185-230.
2. Bharadwaj, S., Shah, V., Tariq, F., Damartoski, B., and Prasad, G. L., 2005, Amino terminal, but not the carboxy terminal, sequences of tropomyosin-1 are essential for the induction of stress fiber assembly in neoplastic cells. Cancer Lett. 229:253-260.
3. Blanchoin, L., Pollard, T. D., and Hitchcock-DeGregori, S. E., 2001, Inhibition of the Arp2/3 complex-nucleated actin polymerization and branch formation by tropomyosin. Curr. Biol. 11:1300-1304.
4. Braverman, R. H., Cooper, H. L., Lee, H. S., and Prasad, G. L., 1996, Anti-oncogenic effects of tropomyosin: isoform specifi city and importance of protein coding sequences. Oncogene 13:537-545.
5. Bremel, R. D., and Weber, A., 1972, Cooperation within actin filament in vertebrate skeletal muscle. Nat. New Biol. 238:97-101.
6. Broschat, K. O., 1990, Tropomyosin prevents depolymerization of actin filaments from the pointed end. J. Biol. Chem. 265:21323-21329.
7. Brown, J. H., Kim, K. H., Jun, G., Greenfield, N. J., Dominguez, R., Volkmann, N., Hitchcock-DeGregori, S. E., and Cohen, C., 2001, Deciphering the design of the tropomyosin molecule. Proc. Natl. Acad. Sci. USA 98:8496-8501.
8. Bryce, N. S., Schevzov, G., Ferguson, V., Percival, J. M., Lin, J. J., Matsumura, F., Bamburg, J. R., Jeffrey, P. L., Hardeman, E. C., Gunning, P., and Weinberger, R. P., 2003, Specifi cation of actin filament function and molecular composition by tropomyosin isoforms. Mol. Biol. Cell 14:1002-1016.
9. Butters, C. A., Willadsen, K. A., and Tobacman, L. S., 1993, Cooperative interactions between adjacent troponin-tropomyosin complexes may be transmitted through the actin filament. J. Biol. Chem. 268:15565-15570.
10. Cassell, M., and Tobacman, L. S., 1996, Opposite effects of myosin subfragment 1 on binding of cardiac troponin and tropomyosin to the thin filament. J. Biol. Chem. 271:12867-12872.
11. Cho, Y. J., Liu, J., and Hitchcock-DeGregori, S. E., 1990, The amino terminus of muscle tropomyosin is a major determinant for function. J. Biol. Chem. 265:538-545.
12. Cooper, H. L., Feuerstein, N., Noda, M., and Bassin, R. H., 1985, Suppression of tropomyosin synthesis, a common biochemical feature of oncogenesis by structurally diverse retroviral oncogenes. Mol. Cell. Biol. 5:972-983.
13. DesMarais, V., Ichetovkin, I., Condeelis, J., and Hitchcock-DeGregori, S. E., 2002, Spatial regulation of actin dynamics: a tropomyosin-free, actin-rich compartment at the leading edge. J. Cell Sci. 115:4649-4660.
14. Eaton, B. L., 1976, Tropomyosin binding to F-actin induced by myosin heads. Science 192:1337-1339.
15. Ebashi, S., and Endo, M., 1968, Calcium Ion and Muscle Contraction. Prog. Biophys. Mol. Biol. 18:125-183.
16. Flicker, P. F., Phillips, G. N., Jr., and Cohen, C., 1982, Troponin and its interactions with tropomyosin. An electron microscope study. J. Mol. Biol. 162:495-501.
17. Fujime, S., and Ishiwata, S., 1971, Dynamic study of F-actin by quasielastic scattering of laser light. J. Mol. Biol. 62:251-265.
18. Geeves, M. A., and Lehrer, S. S., 1994, Dynamics of the muscle thin filament regulatory switch: the size of the cooperative unit. Biophys. J. 67:273-282.
19. Gimona, M., Kazzaz, J. A., and Helfman, D. M., 1996, Forced expression of tropomyosin 2 or 3 in v-Ki-ras-transformed fibroblasts results in distinct phenotypic effects. Proc. Natl. Acad. Sci. USA 93:9618-9623.
20. Gordon, A. M., Homsher, E., and Regnier, M., 2000, Regulation of contraction in striated muscle. Physiol. Rev. 80:853-924.
21. Greenfield, N. J., Montelione, G. T., Farid, R. S., and Hitchcock-DeGregori, S. E., 1998, The structure of the N-terminus of striated muscle alpha-tropomyosin in a chimeric peptide: nuclear magnetic resonance structure and circular dichroism studies. Biochemistry 37:7834-7843.
22. Greenfield, N. J., Palm, T., and Hitchcock-DeGregori, S. E., 2002, Structure and interactions of the carboxyl terminus of striated muscle ?-tropomyosin: It is important to be flexible. Biophys. J. 83:2754-2766.
23. Greenfield, N. J., Swapna, G. V., Huang, Y., Palm, T., Graboski, S., Montelione, G. T., and Hitchcock-DeGregori, S. E., 2003, The structure of the carboxyl terminus of striated alpha-tropomyosin in solution reveals an unusual parallel arrangement of interacting alpha-helices. Biochemistry 42:614-619.
24. Gunning, P. W., Schevzov, G., Kee, A. J., and Hardeman, E. C., 2005, Tropomyosin isoforms: divining rods for actin cytoskeleton function. Trends Cell Biol. 15:333-341.
25. Gupton, S. L., Anderson, K. L., Kole, T. P., Fischer, R. S., Ponti, A., Hitchcock-DeGregori, S. E., Danuser, G., Fowler, V. M., Wirtz, D., Hanein, D., and Waterman-Storer, C. M., 2005, Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin. J. Cell. Biol. 168:619-631.
26. Hammell, R. L., and Hitchcock-DeGregori, S. E., 1996, Mapping the functional domains within the carboxyl terminus of alpha-tropomyosin encoded by the alternatively spliced ninth exon. J. Biol. Chem. 271:4236- 4242.
27. Hammell, R. L., and Hitchcock-DeGregori, S. E., 1997, The sequence of the alternatively spliced sixth exon of alpha-tropomyosin is critical for cooperative actin binding but not for interaction with troponin. J. Biol. Chem. 272:22409-22416.
28. Heald, R. W., and Hitchcock-DeGregori, S. E., 1988, The structure of the amino terminus of tropomyosin is critical for binding to actin in the absence and presence of troponin. J. Biol. Chem. 263:5254-5259.
29. Heeley, D. H., Smillie, L. B., and Lohmeier-Vogel, E. M., 1989, Effects of deletion of tropomyosin overlap on regulated actomyosin subfragment 1 ATPase. Biochem. J. 258:831-836.
30. Hendricks, M., and Weintraub, H., 1981, Tropomyosin is decreased in transformed cells. Proc. Natl. Acad. Sci. USA 78:5633-5637.
31. Hitchcock, S. E., Carisson, L., and Lindberg, U., 1976, Depolymerization of F-actin by deoxyribonuclease I. Cell 7:531-542.
32. Hitchcock-DeGregori, S. E., and An, Y., 1996, Integral repeats and a continuous coiled coil are required for binding of striated muscle tropomyosin to the regulated actin filament. J. Biol. Chem. 271:3600-3603.
33. Hitchcock-DeGregori, S. E., Lewis, S. F., and Mistrik, M., 1988, Lysine reactivities of tropomyosin complexed with troponin. Arch. Biochem. Biophys. 264:410-416.
34. Hitchcock-DeGregori, S. E., Song, Y., and Greenfield, N. J., 2002, Functions of tropomyosin's periodic repeats. Biochemistry 41:15036-15044.
35. Hitchcock-DeGregori, S. E., Song, Y., and Moraczewska, J., 2001, Importance of internal regions and the overall length of tropomyosin for actin binding and regulatory function. Biochemistry 40:2104-2112.
36. Hitchcock-DeGregori, S. E., and Varnell, T. A., 1990, Tropomyosin has discrete actin-binding sites with sevenfold and fourteenfold periodicities. J. Mol. Biol. 214:885-896.
37. Ishii, Y., and Lehrer, S. S., 1990, Excimer fluorescence of pyrenyliodoacetamide-labeled tropomyosin: a probe of the state of tropomyosin in reconstituted muscle thin filaments. Biochemistry 29:1160-1166.
38. Ishikawa, R., Yamashiro, S., and Matsumura, F., 1989, Differential modulation of actin-severing activity of gelsolin by multiple isoforms of cultured rat cell tropomyosin. Potentiation of protective ability of tropomyosins by 83-kDa nonmuscle caldesmon. J. Biol. Chem. 264:7490-7497.
39. Johnson, P., and Smillie, L. B., 1977, Polymerizability of rabbit skeletal tropomyosin: effects of enzymic and chemical modifications. Biochemistry 16:2264-2269.
40. Kostyukova, A. S., and Hitchcock-DeGregori, S. E., 2004, Effect of the structure of the N terminus of tropomyosin on tropomodulin function. J. Biol. Chem. 279:5066-5071.
41. Kwok, S. C., and Hodges, R. S., 2004, Stabilizing and destabilizing clusters in the hydrophobic core of long two-stranded alpha-helical coiled-coils. J. Biol. Chem. 279:21576-21588.
42. Landis, C., Back, N., Homsher, E., and Tobacman, L. S., 1999, Effects of tropomyosin internal deletions on thin filament function. J. Biol. Chem. 274:31279-31285.
43. Landis, C. A., Bobkova, A., Homsher, E., and Tobacman, L. S., 1997, The active state of the thin filament is destabilized by an internal deletion in tropomyosin. J. Biol. Chem. 272:14051-14056.
44. Li, Y., Mui, S., Brown, J. H., Strand, J., Reshetnikova, L., Tobacman, L. S., and Cohen, C., 2002, The crystal structure of the C-terminal fragment of striated-muscle alpha-tropomyosin reveals a key troponin T recognition site. Proc. Natl. Acad. Sci. USA 99:7378-7383.
45. Lin, J. J., Hegmann, T. E., and Lin, J. L., 1988, Differential localization of tropomyosin isoforms in cultured nonmuscle cells. J. Cell. Biol. 107:563-572.
46. McLachlan, A. D., and Stewart, M., 1976, The 14-fold periodicity in alpha-tropomyosin and the interaction with actin. J. Mol. Biol. 103:271-298.
47. Mahadev, K., Raval, G., Bharadwaj, S., Willingham, M. C., Lange, E. M., Vonderhaar, B., Salomon, D., and Prasad, G. L., 2002, Suppression of the transformed phenotype of breast cancer by tropomyosin-1. Exp. Cell Res. 279:40-51.
48. Matsumura, F., Lin, J. J., Yamashiro-Matsumura, S., Thomas, G. P., and Topp, W. C. (1983a). Differential expression of tropomyosin forms in the microfilaments isolated from normal and transformed rat cultured cells. J. Biol. Chem. 258:13954-13964.
49. Matsumura, F., Yamashiro-Matsumura, S., and Lin, J. J. (1983b). Isolation and characterization of tropomyosin-containing microfilaments from cultured cells. J. Biol. Chem. 258:6636-6644.
50. Monteiro, P. B., Lataro, R. C., Ferro, J. A., and Reinach, F. C., 1994, Functional alpha tropomyosin produced in Escherichia coli. A dipeptide extension can substitute the amino-terminal acetyl group. J. Biol. Chem. 269.
51. Moraczewska, J., and Hitchcock-DeGregori, S. E., 2000, Independent functions for the N- and C-termini in the overlap region of tropomyosin. Biochemistry 39:6891-6897.
52. Pan, B. S., Gordon, A. M., and Luo, Z. X., 1989, Removal of tropomyosin overlap modifies cooperative binding of myosin S-1 to reconstituted thin filaments of rabbit striated muscle. J. Biol. Chem. 264:8495-8498.
53. Percival, J. M., Hughes, J. A., Brown, D. L., Schevzov, G., Heimann, K., Vrhovski, B., Bryce, N., Stow, J. L., and Gunning, P. W., 2004, Targeting of a tropomyosin isoform to short microfilaments associated with the Golgi complex. Mol. Biol. Cell 15:268-280.
54. Perry, S. V., 2001, Vertebrate tropomyosin: distribution, properties and function. J. Muscle Res. Cell Motil. 22:5-49.
55. Phillips, G. N., Jr., 1986, Construction of an atomic model for tropomyosin and implications for interactions with actin. J. Mol. Biol. 192:128-131.
56. Pollard, T. D., and Borisy, G. G., 2003, Cellular motility driven by assembly and disassembly of actin filaments. Cell 112:453-465.
57. Raval, G. N., Bharadwaj, S., Levine, E. A., Willingham, M. C., Geary, R. L., Kute, T., and Prasad, G. L., 2003, Loss of expression of tropomyosin-1, a novel class II tumor suppressor that induces anoikis, in primary breast tumors. Oncogene 22:6194-6203.
58. Singh, A., and Hitchcock-DeGregori, S. E., 2006, Dual requirement for flexibility and specificity for binding of the coiled coil tropomyosin to its target, actin. Structure, 14:43-50.
59. Tang, N., and Ostap, E. M., 2001, Motor domain-dependent localization of myo1b (myr-1). Curr. Biol. 11:1131-1135.
60. Tobacman, L. S., and Butters, C. A., 2000, A new model of cooperative myosin-thin filament binding [In Process Citation]. J. Biol. Chem. 275:27587-27593.
61. Ueno, H., Tawada, Y., and Ooi, T., 1976, Properties of non-polymerizable tropomyosin obtained by carboxy-peptidase A digestion. J. Biochem. (Tokyo) 80:283-290.
62. Urbancikova, M., and Hitchcock-DeGregori, S. E., 1994, Requirement of amino-terminal modification for striated muscle alpha- tropomyosin function. J. Biol. Chem. 269:24310-24315.
63. Walsh, T. P., Trueblood, C. E., Evans, R., and Weber, A., 1985, Removal of tropomyosin overlap and the co-operative response to increasing calcium concentrations of the acto-subfragment-1 ATPase. J. Mol. Biol. 182:265-269.
64. Wang, C. L., 2001, Caldesmon and smooth-muscle regulation. Cell Biochem. Biophys. 35:275-88.
65. Whitby, F. G., and Phillips, G. N., Jr., 2000, Crystal structure of tropomyosin at 7 Angstroms resolution. Proteins 38:49-59.
66. Xu, C., Craig, R., Tobacman, L., Horowitz, R., and Lehman, W., 1999, Tropomyosin positions in regulated thin filaments revealed by cryoelectron microscopy. Biophys. J. 77:985-992.