-
1
-
-
0037423296
-
Essential role of the prion protein N-terminus in subcellular trafficking and half-life of PrPc
-
Nunziante, M. Gilch, S. Schatzl, HM. (2003) Essential role of the prion protein N-terminus in subcellular trafficking and half-life of PrPc. Journal of Biological Chemistry 278(6), 3726-3734.
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.6
, pp. 3726-3734
-
-
Nunziante, M.1
Gilch, S.2
Schatzl, H.M.3
-
2
-
-
0037665405
-
Determinants of the in vivo folding of the prion protein: A bipartate function of helix 1 in folding and aggregation
-
Winklhofer, KF., Heske, J., Heller, U., Reintjes, A., Muranyi, W., Moarefi, I., Tatzelt, J. (2003) Determinants of the in vivo folding of the prion protein: a bipartate function of helix 1 in folding and aggregation. Journal of Biological Chemistry 278(17), 14961-14970.
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.17
, pp. 14961-14970
-
-
Winklhofer, K.F.1
Heske, J.2
Heller, U.3
Reintjes, A.4
Muranyi, W.5
Moarefi, I.6
Tatzelt, J.7
-
3
-
-
0028844207
-
Copper binding to the N-terminal tandem repeat region of mammalian and avian prion protein: Structural studies using synthetic peptides
-
Hornshaw, MP., McDermott, JR., Candy, JM., Lakey, JH. (1995) Copper binding to the N-terminal tandem repeat region of mammalian and avian prion protein: structural studies using synthetic peptides. Biochemical and Biophysical Research Communications 214(3), 993-999.
-
(1995)
Biochemical and Biophysical Research Communications
, vol.214
, Issue.3
, pp. 993-999
-
-
Hornshaw, M.P.1
McDermott, J.R.2
Candy, J.M.3
Lakey, J.H.4
-
4
-
-
0031444294
-
The cellular prion protein binds copper in vivo
-
Brown, DR., Qin, K., Herms, JW., Madlung, A., Manson, J., Strome, R., Fraser, PE., Kruck, T., Bohlen, A., Schulz-Schaeffer, W., Giese, A., Westaway, D., Kretzschmar, H. (1997) The cellular prion protein binds copper in vivo. Nature 390, 684-687.
-
(1997)
Nature
, vol.390
, pp. 684-687
-
-
Brown, D.R.1
Qin, K.2
Herms, J.W.3
Madlung, A.4
Manson, J.5
Strome, R.6
Fraser, P.E.7
Kruck, T.8
Bohlen, A.9
Schulz-Schaeffer, W.10
Giese, A.11
Westaway, D.12
Kretzschmar, H.13
-
5
-
-
0035902869
-
91-231 and its low-resolution structure in solution
-
91-231 and its low-resolution structure in solution. Journal of Molecular Biology 311, 467-473.
-
(2001)
Journal of Molecular Biology
, vol.311
, pp. 467-473
-
-
Hasnain, S.S.1
Murphy, L.M.2
Strange, R.W.3
Grossmann, J.G.4
Clarke, A.R.5
Jackson, G.S.6
Collinge, J.7
-
6
-
-
0035902531
-
Location and properties of metal-binding sites on the human prion protein
-
Jackson, GS., Murray, I., Hosszu, LLP., Gibbs, N., Waltho, JP., Clarke, AR., Collinge, J. (2001) Location and properties of metal-binding sites on the human prion protein. Proceedings of the National Academy of Sciences USA. 98(15), 8531-8535.
-
(2001)
Proceedings of the National Academy of Sciences USA
, vol.98
, Issue.15
, pp. 8531-8535
-
-
Jackson, G.S.1
Murray, I.2
Hosszu, L.L.P.3
Gibbs, N.4
Waltho, J.P.5
Clarke, A.R.6
Collinge, J.7
-
7
-
-
0032509499
-
Copper stimulates endocytosis of the prion protein
-
Pauly, PC., Harris, DA. (1998) Copper stimulates endocytosis of the prion protein. Journal of Biological Chemistry 273(50), 33107-33110.
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.50
, pp. 33107-33110
-
-
Pauly, P.C.1
Harris, D.A.2
-
8
-
-
0034790685
-
Internalisation of mammalian fluorescent cellular prion protein and N-terminal deletion mutants in living cells
-
Lee, KS., Magalhaes, AC., Zanata, SM., Brentani, RR., Martins, VR. Prado, MA. (2001) Internalisation of mammalian fluorescent cellular prion protein and N-terminal deletion mutants in living cells. Journal of Neurochemistry 79(1), 79-87.
-
(2001)
Journal of Neurochemistry
, vol.79
, Issue.1
, pp. 79-87
-
-
Lee, K.S.1
Magalhaes, A.C.2
Zanata, S.M.3
Brentani, R.R.4
Martins, V.R.5
Prado, M.A.6
-
9
-
-
0042313964
-
The mechanism of internalisation of glycosylphosphatidylinositol-anchored prion protein
-
Sunyach, C., Jen, A., Deng, J., Fitzgerald, KT., Frobert, Y., Grassi, J., McCaffrey, MW., Morris, R. (2003) The mechanism of internalisation of glycosylphosphatidylinositol-anchored prion protein. EMBO Journal 22(14), 3591-3601.
-
(2003)
EMBO Journal
, vol.22
, Issue.14
, pp. 3591-3601
-
-
Sunyach, C.1
Jen, A.2
Deng, J.3
Fitzgerald, K.T.4
Frobert, Y.5
Grassi, J.6
McCaffrey, M.W.7
Morris, R.8
-
10
-
-
24944491725
-
Copper binding is the governing determinant of prion protein turnover
-
Haigh, CL., Edwards, KE., Brown, DR. (2005) Copper binding is the governing determinant of prion protein turnover. Molecular and Cellular Neuroscience 30, 186-96.
-
(2005)
Molecular and Cellular Neuroscience
, vol.30
, pp. 186-196
-
-
Haigh, C.L.1
Edwards, K.E.2
Brown, D.R.3
-
11
-
-
0031905248
-
Effects of copper on survival of prion protein knockout neurons and glia
-
Brown, DR., Schmidt, B., Kretzschmar, HA. (1998) Effects of copper on survival of prion protein knockout neurons and glia. Journal of Neurochemistry 70, 1686-93.
-
(1998)
Journal of Neurochemistry
, vol.70
, pp. 1686-1693
-
-
Brown, D.R.1
Schmidt, B.2
Kretzschmar, H.A.3
-
12
-
-
0034764599
-
Oxidative impairment in scrapie-infected mice is associated with brain metal perturbations and altered anti-oxidant activities
-
Wong, BS., Brown, DR., Pan, T., Whitemann, M., Liu, T., Bu, X., Li, R., Gambetti, P., Olesik, J., Rubenstein, R., Sy, MS. (2001) Oxidative impairment in scrapie-infected mice is associated with brain metal perturbations and altered anti-oxidant activities. Journal of Neurochemistry 79, 689-698.
-
(2001)
Journal of Neurochemistry
, vol.79
, pp. 689-698
-
-
Wong, B.S.1
Brown, D.R.2
Pan, T.3
Whitemann, M.4
Liu, T.5
Bu, X.6
Li, R.7
Gambetti, P.8
Olesik, J.9
Rubenstein, R.10
Sy, M.S.11
-
13
-
-
0037083888
-
Metal imbalance and compromised anti-oxidant function are early changes in prion disease
-
Thackray, AM., Knight, R., Haswell, SJ., Bujdoso, R., Brown, DR. (2002) Metal imbalance and compromised anti-oxidant function are early changes in prion disease. Biochemical Journal 362, 253-258.
-
(2002)
Biochemical Journal
, vol.362
, pp. 253-258
-
-
Thackray, A.M.1
Knight, R.2
Haswell, S.J.3
Bujdoso, R.4
Brown, D.R.5
-
14
-
-
0032169565
-
Prion protein expression and superoxide dismutase activity
-
Brown, DR., Besinger, A. (1998) Prion protein expression and superoxide dismutase activity. Biochemical Journal 334, 423-429.
-
(1998)
Biochemical Journal
, vol.334
, pp. 423-429
-
-
Brown, D.R.1
Besinger, A.2
-
15
-
-
0035158321
-
Antioxidant activity related to copper binding of native prion protein
-
Brown, DR., Clive, C., Haswell, SJ. (2001) Antioxidant activity related to copper binding of native prion protein. Journal of Neurochemistry 76, 69-76.
-
(2001)
Journal of Neurochemistry
, vol.76
, pp. 69-76
-
-
Brown, D.R.1
Clive, C.2
Haswell, S.J.3
-
16
-
-
0034654304
-
Consequences of manganese replacement of copper for prion protein function and proteinase resistance
-
Brown, DR., Hafiz, F., Glasssmith, LL., Wong, BS., Jones, IM., Clive, C., Haswell, SJ. (2000) Consequences of manganese replacement of copper for prion protein function and proteinase resistance. EMBO Journal 19(6), 1180-1186.
-
(2000)
EMBO Journal
, vol.19
, Issue.6
, pp. 1180-1186
-
-
Brown, D.R.1
Hafiz, F.2
Glasssmith, L.L.3
Wong, B.S.4
Jones, I.M.5
Clive, C.6
Haswell, S.J.7
-
17
-
-
0042381229
-
A novel method of generating neuronal cell lines from gene-knockout mice to study prion protein membrane orientation
-
Holme, A., Daniels, M., Sassoon, J., Brown, DR. A novel method of generating neuronal cell lines from gene-knockout mice to study prion protein membrane orientation. European Journal of Neuroscience 18, 571-579.
-
European Journal of Neuroscience
, vol.18
, pp. 571-579
-
-
Holme, A.1
Daniels, M.2
Sassoon, J.3
Brown, D.R.4
-
18
-
-
0003836971
-
-
third edition, Oxford Scientific Publications, Oxford, UK
-
Dawson, RM., Elliott, DC., Elliott, WH., Jones, KM. (1994) Data for Biochemical Research (third edition). Oxford Scientific Publications, Oxford, UK.
-
(1994)
Data for Biochemical Research
-
-
Dawson, R.M.1
Elliott, D.C.2
Elliott, W.H.3
Jones, K.M.4
-
19
-
-
0032428645
-
Hypervalent chromium mimics reactive oxygen species as measured by the oxidant-sensitive dyes 2',7'-dichlorofluorescin and dihydrorhodamine
-
Martin, BD., Schoenhard, JA., Sugden, KD. (1998) Hypervalent chromium mimics reactive oxygen species as measured by the oxidant-sensitive dyes 2',7'-dichlorofluorescin and dihydrorhodamine. Chemical Research and Toxicology 11(12), 1402-10.
-
(1998)
Chemical Research and Toxicology
, vol.11
, Issue.12
, pp. 1402-1410
-
-
Martin, B.D.1
Schoenhard, J.A.2
Sugden, K.D.3
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