Glucose Uptake and Runx2 Synergize to Orchestrate Osteoblast Differentiation and Bone Formation

Cell

Volumn 161, Issue 7, 2015, Pages 1576-1591

  Wei, Jianwen ^a   Shimazu, Junko ^a   Makinistoglu, Munevver P ^a   Maurizi, Antonio ^a   Kajimura, Daisuke ^a   Zong, Haihong ^b   Takarada, Takeshi ^c   Lezaki, Takashi ^c   Pessin, Jeffrey E ^b   Hinoi, Eiichi ^c   Karsenty, Gerard ^a  

^a Columbia University ^*  (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; COLLAGEN TYPE 1; COLLAGEN TYPE 1 ALPHA; CYCLIN D2; CYCLIN DEPENDENT KINASE 4; CYCLIN E; CYCLIN E1; FATTY ACID; GLUCOSE; GLUCOSE TRANSPORTER 1; GLYCOGEN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; OSTEOCALCIN; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR RUNX3; UNCLASSIFIED DRUG; RUNX2 PROTEIN, MOUSE; SLC2A1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; BONE DEVELOPMENT; BONE MASS; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL PROLIFERATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; FEMALE; GENE DELETION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE INTAKE; GLUCOSE TOLERANCE; GLUCOSE TRANSPORT; GLYCOGEN ANALYSIS; IN SITU HYBRIDIZATION; INSULIN BLOOD LEVEL; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STEADY STATE; UBIQUITINATION; UPREGULATION; AMINO ACID SEQUENCE; ANIMAL; ANIMAL EMBRYO; ANTAGONISTS AND INHIBITORS; CYTOLOGY; GENETICS; HOMEOSTASIS; METABOLISM; SEQUENCE ALIGNMENT; SKULL;

AMINO ACID SEQUENCE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELL DIFFERENTIATION; CORE BINDING FACTOR ALPHA 1 SUBUNIT; EMBRYO, MAMMALIAN; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; HOMEOSTASIS; MICE; OSTEOBLASTS; OSTEOGENESIS; SEQUENCE ALIGNMENT; SKULL;

EID: 84934340141     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2015.05.029     Document Type: Article

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