-
1
-
-
84861669644
-
Doxil(R)-the First FDA-approved Nano-drug: Lessons Learned
-
Barenholz, Y. Doxil(R)-the First FDA-approved Nano-drug: Lessons Learned J. Controlled Release 2012, 160, 117-134
-
(2012)
J. Controlled Release
, vol.160
, pp. 117-134
-
-
Barenholz, Y.1
-
2
-
-
84858665432
-
Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile
-
Hrkach, J.; Von Hoff, D.; Ali, M. M.; Andrianova, E.; Auer, J.; Campbell, T.; De Witt, D.; Figa, M.; Figueiredo, M.; Horhota, A. Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile Sci. Transl. Med. 2012, 4, 128ra39
-
(2012)
Sci. Transl. Med.
, vol.4
, pp. 128ra39
-
-
Hrkach, J.1
Von Hoff, D.2
Ali, M.M.3
Andrianova, E.4
Auer, J.5
Campbell, T.6
De Witt, D.7
Figa, M.8
Figueiredo, M.9
Horhota, A.10
-
3
-
-
0022858683
-
A New Concept for Macromolecular Therapeutics in Cancer Chemotherapy: Mechanism of Tumoritropic Accumulation of Proteins and the Antitumor Agent Smancs
-
Matsumura, Y.; Maeda, H. A New Concept for Macromolecular Therapeutics in Cancer Chemotherapy: Mechanism of Tumoritropic Accumulation of Proteins and the Antitumor Agent Smancs Cancer Res. 1986, 46, 6387-6392
-
(1986)
Cancer Res.
, vol.46
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
4
-
-
0029444559
-
Surrogate Cells or Trojan Horses. The Discovery of Liposomes
-
Bangham, A. D. Surrogate Cells or Trojan Horses. The Discovery of Liposomes BioEssays 1995, 17, 1081-1088
-
(1995)
BioEssays
, vol.17
, pp. 1081-1088
-
-
Bangham, A.D.1
-
5
-
-
33747762229
-
Exploiting the Enhanced Permeability and Retention Effect for Tumor Targeting
-
Iyer, A. K.; Khaled, G.; Fang, J.; Maeda, H. Exploiting the Enhanced Permeability and Retention Effect for Tumor Targeting Drug Discovery Today 2006, 11, 812-818
-
(2006)
Drug Discovery Today
, vol.11
, pp. 812-818
-
-
Iyer, A.K.1
Khaled, G.2
Fang, J.3
Maeda, H.4
-
6
-
-
42349094203
-
Nanoparticles in Medicine: Therapeutic Applications and Developments
-
Zhang, L.; Gu, F. X.; Chan, J. M.; Wang, A. Z.; Langer, R. S.; Farokhzad, O. C. Nanoparticles in Medicine: Therapeutic Applications and Developments Clin. Pharm. Ther. 2008, 83, 761-769
-
(2008)
Clin. Pharm. Ther.
, vol.83
, pp. 761-769
-
-
Zhang, L.1
Gu, F.X.2
Chan, J.M.3
Wang, A.Z.4
Langer, R.S.5
Farokhzad, O.C.6
-
7
-
-
0141988568
-
Fundamental Concepts of the Angiogenic Process
-
Folkman, J. Fundamental Concepts of the Angiogenic Process Curr. Mol. Med. 2003, 3, 643-651
-
(2003)
Curr. Mol. Med.
, vol.3
, pp. 643-651
-
-
Folkman, J.1
-
8
-
-
79952284127
-
Hallmarks of Cancer: The Next Generation
-
Hanahan, D.; Weinberg, R. A. Hallmarks of Cancer: The Next Generation Cell 2011, 144, 646-674
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
9
-
-
60749108001
-
Polymeric Drugs for Efficient Tumor-Targeted Drug Delivery Based on EPR-Effect
-
Maeda, H.; Bharate, G. Y.; Daruwalla, J. Polymeric Drugs for Efficient Tumor-Targeted Drug Delivery Based on EPR-Effect Eur. J. Pharm. Biopharm. 2009, 71, 409-419
-
(2009)
Eur. J. Pharm. Biopharm.
, vol.71
, pp. 409-419
-
-
Maeda, H.1
Bharate, G.Y.2
Daruwalla, J.3
-
10
-
-
79953054576
-
The EPR effect: Unique Features of Tumor Blood Vessels for Drug Delivery, Factors Involved, and Limitations and Augmentation of the Effect
-
Fang, J.; Nakamura, H.; Maeda, H. The EPR effect: Unique Features of Tumor Blood Vessels for Drug Delivery, Factors Involved, and Limitations and Augmentation of the Effect Adv. Drug Delivery Rev. 2011, 63, 136-151
-
(2011)
Adv. Drug Delivery Rev.
, vol.63
, pp. 136-151
-
-
Fang, J.1
Nakamura, H.2
Maeda, H.3
-
11
-
-
84869500651
-
Tumor Heterogeneity and its Implication for Drug Delivery
-
Denison, T. A.; Bae, Y. H. Tumor Heterogeneity and its Implication for Drug Delivery J. Controlled Release 2012, 164, 187-191
-
(2012)
J. Controlled Release
, vol.164
, pp. 187-191
-
-
Denison, T.A.1
Bae, Y.H.2
-
12
-
-
0024461206
-
Tumor Vascular Permeability Factor Stimulates Endothelial Cell Growth and Angiogenesis
-
Connolly, D. T.; Heuvelman, D. M.; Nelson, R.; Olander, J. V.; Eppley, B. L.; Delfino, J. J.; Siegel, N. R.; Leimgruber, R. M.; Feder, J. Tumor Vascular Permeability Factor Stimulates Endothelial Cell Growth and Angiogenesis J. Clin. Invest. 1989, 84, 1470-1478
-
(1989)
J. Clin. Invest.
, vol.84
, pp. 1470-1478
-
-
Connolly, D.T.1
Heuvelman, D.M.2
Nelson, R.3
Olander, J.V.4
Eppley, B.L.5
Delfino, J.J.6
Siegel, N.R.7
Leimgruber, R.M.8
Feder, J.9
-
13
-
-
0034046024
-
The Influence of Cytotoxicity of Macromolecules and of VEGF Gene Modulated Vascular Permeability on the Enhanced Permeability and Retention Effect in Resistant Solid Tumors
-
Minko, T.; Kopeckova, P.; Pozharov, V.; Jensen, K. D.; Kopecek, J. The Influence of Cytotoxicity of Macromolecules and of VEGF Gene Modulated Vascular Permeability on the Enhanced Permeability and Retention Effect in Resistant Solid Tumors Pharm. Res. 2000, 17, 505-514
-
(2000)
Pharm. Res.
, vol.17
, pp. 505-514
-
-
Minko, T.1
Kopeckova, P.2
Pozharov, V.3
Jensen, K.D.4
Kopecek, J.5
-
14
-
-
0141786833
-
Cardiac Safety of Liposomal Anthracyclines
-
Safra, T. Cardiac Safety of Liposomal Anthracyclines Oncologist 2003, 8, 17-24
-
(2003)
Oncologist
, vol.8
, pp. 17-24
-
-
Safra, T.1
-
15
-
-
0035127410
-
Effective Targeting of Solid Tumors in Patients with Locally Advanced Cancers by Radiolabeled Pegylated Liposomes
-
Harrington, K. J.; Mohammadtaghi, S.; Uster, P. S.; Glass, D.; Peters, A. M.; Vile, R. G.; Stewart, J. S. Effective Targeting of Solid Tumors in Patients with Locally Advanced Cancers by Radiolabeled Pegylated Liposomes Clin. Cancer Res. 2001, 7, 243-254
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 243-254
-
-
Harrington, K.J.1
Mohammadtaghi, S.2
Uster, P.S.3
Glass, D.4
Peters, A.M.5
Vile, R.G.6
Stewart, J.S.7
-
16
-
-
0025277168
-
Preliminary report: Imaging of Kaposi Sarcoma and Lymphoma in AIDS with Indium-111-labelled Liposomes
-
Presant, C. A.; Blayney, D.; Proffitt, R. T.; Turner, A. F.; Williams, L. E.; Nadel, H. I.; Kennedy, P.; Wiseman, C.; Gala, K.; Crossley, R. J. Preliminary report: Imaging of Kaposi Sarcoma and Lymphoma in AIDS with Indium-111-labelled Liposomes Lancet 1990, 335, 1307-1309
-
(1990)
Lancet
, vol.335
, pp. 1307-1309
-
-
Presant, C.A.1
Blayney, D.2
Proffitt, R.T.3
Turner, A.F.4
Williams, L.E.5
Nadel, H.I.6
Kennedy, P.7
Wiseman, C.8
Gala, K.9
Crossley, R.J.10
-
17
-
-
0031038532
-
Liposomal Distribution in Malignant Glioma: Possibilities for Therapy
-
Khalifa, A.; Dodds, D.; Rampling, R.; Paterson, J.; Murray, T. Liposomal Distribution in Malignant Glioma: Possibilities for Therapy Nucl. Med. Commun. 1997, 18, 17-23
-
(1997)
Nucl. Med. Commun.
, vol.18
, pp. 17-23
-
-
Khalifa, A.1
Dodds, D.2
Rampling, R.3
Paterson, J.4
Murray, T.5
-
18
-
-
0023681925
-
Successful Imaging of Human Cancer with Indium-111-labeled Phospholipid Vesicles
-
Presant, C. A.; Proffitt, R. T.; Turner, A. F.; Williams, L. E.; Winsor, D.; Werner, J. L.; Kennedy, P.; Wiseman, C.; Gala, K.; McKenna, R. J. Successful Imaging of Human Cancer with Indium-111-labeled Phospholipid Vesicles Cancer 1988, 62, 905-911
-
(1988)
Cancer
, vol.62
, pp. 905-911
-
-
Presant, C.A.1
Proffitt, R.T.2
Turner, A.F.3
Williams, L.E.4
Winsor, D.5
Werner, J.L.6
Kennedy, P.7
Wiseman, C.8
Gala, K.9
McKenna, R.J.10
-
19
-
-
38549112058
-
Translation of New Cancer Treatments from Pet Dogs to Humans
-
Paoloni, M.; Khanna, C. Translation of New Cancer Treatments from Pet Dogs to Humans Nat. Rev. Cancer 2008, 8, 147-156
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 147-156
-
-
Paoloni, M.1
Khanna, C.2
-
20
-
-
0036717382
-
Molecular Imaging of Cancer with Positron Emission Tomography
-
Gambhir, S. S. Molecular Imaging of Cancer with Positron Emission Tomography Nat. Rev. Cancer 2002, 2, 683-693
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 683-693
-
-
Gambhir, S.S.1
-
21
-
-
0016631386
-
Application of Annihilation Coincidence Detection to Transaxial Reconstruction Tomography
-
Phelps, M. E.; Hoffman, E. J.; Mullani, N. A.; Ter-Pogossian, M. M. Application of Annihilation Coincidence Detection to Transaxial Reconstruction Tomography J. Nucl. Med. 1975, 16, 210-224
-
(1975)
J. Nucl. Med.
, vol.16
, pp. 210-224
-
-
Phelps, M.E.1
Hoffman, E.J.2
Mullani, N.A.3
Ter-Pogossian, M.M.4
-
22
-
-
79955482984
-
Positron Emission Tomography Imaging of the Stability of Cu-64 labeled Dipalmitoyl and Distearoyl Lipids in Liposomes
-
Seo, J. W.; Qin, S.; Mahakian, L. M.; Watson, K. D.; Kheirolomoom, A.; Ferrara, K. W. Positron Emission Tomography Imaging of the Stability of Cu-64 labeled Dipalmitoyl and Distearoyl Lipids in Liposomes J. Controlled Release 2011, 151, 28-34
-
(2011)
J. Controlled Release
, vol.151
, pp. 28-34
-
-
Seo, J.W.1
Qin, S.2
Mahakian, L.M.3
Watson, K.D.4
Kheirolomoom, A.5
Ferrara, K.W.6
-
23
-
-
46449084158
-
Molecular Imaging in Drug Development
-
Willmann, J. K.; van Bruggen, N.; Dinkelborg, L. M.; Gambhir, S. S. Molecular Imaging in Drug Development Nat. Rev. Drug Discovery 2008, 7, 591-607
-
(2008)
Nat. Rev. Drug Discovery
, vol.7
, pp. 591-607
-
-
Willmann, J.K.1
Van Bruggen, N.2
Dinkelborg, L.M.3
Gambhir, S.S.4
-
24
-
-
78951482499
-
64Cu Loaded Liposomes as Positron Emission Tomography Imaging Agents
-
Petersen, A. L.; Binderup, T.; Rasmussen, P.; Henriksen, J. R.; Elema, D. R.; Kjaer, A.; Andresen, T. L. 64Cu Loaded Liposomes as Positron Emission Tomography Imaging Agents Biomaterials 2011, 32, 2334-2341
-
(2011)
Biomaterials
, vol.32
, pp. 2334-2341
-
-
Petersen, A.L.1
Binderup, T.2
Rasmussen, P.3
Henriksen, J.R.4
Elema, D.R.5
Kjaer, A.6
Andresen, T.L.7
-
25
-
-
79952463764
-
FDG PET/CT Imaging in Canine Cancer Patients
-
Hansen, A. E.; McEvoy, F.; Engelholm, S. A.; Law, I.; Kristensen, A. T. FDG PET/CT Imaging in Canine Cancer Patients Vet. Radiol. Ultrasound 2011, 52, 201-206
-
(2011)
Vet. Radiol. Ultrasound
, vol.52
, pp. 201-206
-
-
Hansen, A.E.1
McEvoy, F.2
Engelholm, S.A.3
Law, I.4
Kristensen, A.T.5
-
26
-
-
0344958781
-
Delivery of Gamma-Imaging Agents by Liposomes
-
Phillips, W. T. Delivery of Gamma-Imaging Agents by Liposomes Adv. Drug Delivery Rev. 1999, 37, 13-32
-
(1999)
Adv. Drug Delivery Rev.
, vol.37
, pp. 13-32
-
-
Phillips, W.T.1
-
27
-
-
0037681850
-
Pharmacokinetics of Pegylated Liposomal Doxorubicin: Review of Animal and Human Studies
-
Gabizon, A.; Shmeeda, H.; Barenholz, Y. Pharmacokinetics of Pegylated Liposomal Doxorubicin: Review of Animal and Human Studies Clin. Pharmacokinet. 2003, 42, 419-436
-
(2003)
Clin. Pharmacokinet.
, vol.42
, pp. 419-436
-
-
Gabizon, A.1
Shmeeda, H.2
Barenholz, Y.3
-
28
-
-
0035120280
-
Stealth Liposomes and Tumor Targeting: One Step Further in the Quest for the Magic Bullet
-
Gabizon, A. A. Stealth Liposomes and Tumor Targeting: One Step Further in the Quest for the Magic Bullet Clin. Cancer Res. 2001, 7, 223-225
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 223-225
-
-
Gabizon, A.A.1
-
29
-
-
0033884273
-
Influence of Tumour Size on Uptake of (111)ln-DTPA-Labelled Pegylated Liposomes in a Human Tumour Xenograft Model
-
Harrington, K. J.; Rowlinson-Busza, G.; Syrigos, K. N.; Abra, R. M.; Uster, P. S.; Peters, A. M.; Stewart, J. S. Influence of Tumour Size on Uptake of (111)ln-DTPA-Labelled Pegylated Liposomes in a Human Tumour Xenograft Model Br. J. Cancer 2000, 83, 684-688
-
(2000)
Br. J. Cancer
, vol.83
, pp. 684-688
-
-
Harrington, K.J.1
Rowlinson-Busza, G.2
Syrigos, K.N.3
Abra, R.M.4
Uster, P.S.5
Peters, A.M.6
Stewart, J.S.7
-
30
-
-
84861661506
-
Positron Emission Tomography Evaluation of Somatostatin Receptor Targeted 64Cu-TATE-Liposomes in a Human Neuroendocrine Carcinoma Mouse Model
-
Petersen, A. L.; Binderup, T.; Jølck, R. I.; Rasmussen, P.; Henriksen, J. R.; Pfeifer, A. K.; Kjaer, A.; Andresen, T. L. Positron Emission Tomography Evaluation of Somatostatin Receptor Targeted 64Cu-TATE-Liposomes in a Human Neuroendocrine Carcinoma Mouse Model J. Controlled Release 2012, 160, 254-263
-
(2012)
J. Controlled Release
, vol.160
, pp. 254-263
-
-
Petersen, A.L.1
Binderup, T.2
Jølck, R.I.3
Rasmussen, P.4
Henriksen, J.R.5
Pfeifer, A.K.6
Kjaer, A.7
Andresen, T.L.8
-
31
-
-
84863646104
-
Nanomedicine: Downsizing Tumour Therapeutics
-
Cheng, C. J.; Saltzman, W. M. Nanomedicine: Downsizing Tumour Therapeutics Nat. Nanotechnol. 2012, 7, 346-347
-
(2012)
Nat. Nanotechnol.
, vol.7
, pp. 346-347
-
-
Cheng, C.J.1
Saltzman, W.M.2
-
32
-
-
84868256944
-
Overcoming Limitations in Nanoparticle Drug Delivery: Triggered, Intravascular Release to Improve Drug Penetration into Tumors
-
Manzoor, A. A.; Lindner, L. H.; Landon, C. D.; Park, J. Y.; Simnick, A. J.; Dreher, M. R.; Das, S.; Hanna, G.; Park, W.; Chilkoti, A. Overcoming Limitations in Nanoparticle Drug Delivery: Triggered, Intravascular Release To Improve Drug Penetration into Tumors Cancer Res. 2012, 72, 5566-5575
-
(2012)
Cancer Res.
, vol.72
, pp. 5566-5575
-
-
Manzoor, A.A.1
Lindner, L.H.2
Landon, C.D.3
Park, J.Y.4
Simnick, A.J.5
Dreher, M.R.6
Das, S.7
Hanna, G.8
Park, W.9
Chilkoti, A.10
-
33
-
-
84862757952
-
Evolutionary Dynamics of Carcinogenesis and Why Targeted Therapy Does Not Work
-
Gillies, R. J.; Verduzco, D.; Gatenby, R. A. Evolutionary Dynamics of Carcinogenesis and Why Targeted Therapy Does Not Work Nat. Rev. Cancer 2012, 12, 487-493
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 487-493
-
-
Gillies, R.J.1
Verduzco, D.2
Gatenby, R.A.3
|