-
1
-
-
45549093204
-
Cidea is associated with lipid droplets and insulin sensitivity in humans
-
Puri, V. et al. Cidea is associated with lipid droplets and insulin sensitivity in humans. Proc. Natl Acad. Sci. USA 105, 7833-7838 (2008)
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 7833-7838
-
-
Puri, V.1
-
2
-
-
55849147331
-
A functional interaction between RIP140 and PGC-1alpha regulates the expression of the lipid droplet protein CIDEA
-
Hallberg, M. et al. A functional interaction between RIP140 and PGC-1alpha regulates the expression of the lipid droplet protein CIDEA. Mol. Cell. Biol. 28, 6785-6795 (2008)
-
(2008)
Mol. Cell. Biol
, vol.28
, pp. 6785-6795
-
-
Hallberg, M.1
-
3
-
-
20044395797
-
A human-specific role of cell death-inducing DFFA (DNA fragmentation factor-alpha)-like effector A (CIDEA) in adipocyte lipolysis and obesity
-
Nordstrom, E. A. et al. A human-specific role of cell death-inducing DFFA (DNA fragmentation factor-alpha)-like effector A (CIDEA) in adipocyte lipolysis and obesity. Diabetes 54, 1726-1734 (2005)
-
(2005)
Diabetes
, vol.54
, pp. 1726-1734
-
-
Nordstrom, E.A.1
-
4
-
-
36849040036
-
Relations of adipose tissue CIDEA gene expression to basal metabolic rate, energy restriction, and obesity: Population-based and dietary intervention studies
-
Gummesson, A. et al. Relations of adipose tissue CIDEA gene expression to basal metabolic rate, energy restriction, and obesity: population-based and dietary intervention studies. J Clin Endocrinol. Metab. 92, 4759-4765 (2007)
-
(2007)
J Clin Endocrinol. Metab
, vol.92
, pp. 4759-4765
-
-
Gummesson, A.1
-
5
-
-
84903779943
-
Adipose tissue CIDEA is associated, independently of weight variation, to change in insulin resistance during a longitudinal weight control dietary program in obese individuals
-
Montastier, E. et al. Adipose tissue CIDEA is associated, independently of weight variation, to change in insulin resistance during a longitudinal weight control dietary program in obese individuals. PLoS ONE 9, e98707 (2014)
-
(2014)
PLoS ONE
, vol.9
, pp. e98707
-
-
Montastier, E.1
-
6
-
-
0041353552
-
Cidea-deficient mice have lean phenotype and are resistant to obesity
-
Zhou, Z. et al. Cidea-deficient mice have lean phenotype and are resistant to obesity. Nature Genet. 35, 49-56 (2003)
-
(2003)
Nature Genet
, vol.35
, pp. 49-56
-
-
Zhou, Z.1
-
7
-
-
77952623888
-
The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation
-
Barbatelli, G. et al. The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation. Am. J. Physiol. 298, E1244-E1253 (2010)
-
(2010)
Am. J. Physiol
, vol.298
, pp. E1244-E1253
-
-
Barbatelli, G.1
-
8
-
-
77950226740
-
Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent UCP1-containing adipocytes molecularly distinct classic brown adipocytes
-
Petrovic, N. et al. Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct classic brown adipocytes. J. Biol. Chem. 285, 7153-7164 (2010)
-
(2010)
J. Biol. Chem
, vol.285
, pp. 7153-7164
-
-
Petrovic, N.1
-
9
-
-
58749091645
-
UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality
-
Feldmann, H. M., Golozoubova, V., Cannon, B. & Nedergaard, J. UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality. Cell Metab. 9, 203-209 (2009)
-
(2009)
Cell Metab
, vol.9
, pp. 203-209
-
-
Feldmann, H.M.1
Golozoubova, V.2
Cannon, B.3
Nedergaard, J.4
-
10
-
-
0025637601
-
A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo
-
Ross, S. R. et al. A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo. Proc. Natl Acad. Sci. USA 87, 9590-9594 (1990)
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 9590-9594
-
-
Ross, S.R.1
-
11
-
-
0026693222
-
Identification of a fat cell enhancer: Analysis of requirements for adipose tissuespecific gene expression
-
Graves, R. A., Tontonoz, P., Platt, K. A., Ross, S. R. & Spiegelman, B. M. Identification of a fat cell enhancer: analysis of requirements for adipose tissuespecific gene expression. J. Cell. Biochem 49, 219-224 (1992)
-
(1992)
J. Cell. Biochem
, vol.49
, pp. 219-224
-
-
Graves, R.A.1
Tontonoz, P.2
Platt, K.A.3
Ross, S.R.4
Spiegelman, B.M.5
-
12
-
-
70349675659
-
Estimating the continuous-Time dynamics of energy and fat metabolism in mice
-
Guo, J. & Hall, K. D. Estimating the continuous-Time dynamics of energy and fat metabolism in mice. PLoS Computat. Biol. 5, e1000511 (2009)
-
(2009)
PLoS Computat. Biol
, vol.5
, pp. e1000511
-
-
Guo, J.1
Hall, K.D.2
-
13
-
-
36849012057
-
Adipocyte death, adipose tissue remodeling, and obesity complications
-
Strissel, K. J. et al. Adipocyte death, adipose tissue remodeling, and obesity complications. Diabetes 56, 2910-2918 (2007)
-
(2007)
Diabetes
, vol.56
, pp. 2910-2918
-
-
Strissel, K.J.1
-
14
-
-
78649869726
-
Hypertrophy-driven adipocyte death overwhelms recruitment under prolonged weight gain
-
Jo, J. et al. Hypertrophy-driven adipocyte death overwhelms recruitment under prolonged weight gain. Biophys. J. 99, 3535-3544 (2010)
-
(2010)
Biophys. J
, vol.99
, pp. 3535-3544
-
-
Jo, J.1
-
15
-
-
84883467905
-
Identification of an adipogenic niche for adipose tissue remodeling and restoration
-
Lee, Y. H., Petkova, A. P. & Granneman, J. G. Identification of an adipogenic niche for adipose tissue remodeling and restoration. Cell Metab. 18, 355-367 (2013)
-
(2013)
Cell Metab
, vol.18
, pp. 355-367
-
-
Lee, Y.H.1
Petkova, A.P.2
Granneman, J.G.3
-
16
-
-
84887502374
-
Tracking adipogenesis during white adipose tissue development, expansion and regeneration
-
Wang, Q. A., Tao, C., Gupta, R. K. & Scherer, P. E. Tracking adipogenesis during white adipose tissue development, expansion and regeneration. Nature Med. 19, 1338-1344 (2013)
-
(2013)
Nature Med
, vol.19
, pp. 1338-1344
-
-
Wang, Q.A.1
Tao, C.2
Gupta, R.K.3
Scherer, P.E.4
-
17
-
-
84883157734
-
Obese adipocytes show ultrastructural features of stressed cells and die of pyroptosis
-
Giordano, A. et al. Obese adipocytes show ultrastructural features of stressed cells and die of pyroptosis. J. Lipid Res. 54, 2423-2436 (2013)
-
(2013)
J. Lipid Res
, vol.54
, pp. 2423-2436
-
-
Giordano, A.1
-
18
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg, S. P. et al. Obesity is associated with macrophage accumulation in adipose tissue. J. Clin. Invest. 112, 1796-1808 (2003)
-
(2003)
J. Clin. Invest
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
-
19
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu, H. et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest. 112, 1821-1830 (2003)
-
(2003)
J. Clin. Invest
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
-
20
-
-
50949108719
-
Dead adipocytes detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice
-
Murano, I. et al. Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice. J. Lipid Res. 49, 1562-1568 (2008)
-
(2008)
J. Lipid Res
, vol.49
, pp. 1562-1568
-
-
Murano, I.1
-
21
-
-
79953211885
-
Mast cells macrophages and crown-like structures distinguish subcutaneous from visceral fat in mice
-
Altintas, M. M. et al. Mast cells, macrophages, and crown-like structures distinguish subcutaneous from visceral fat in mice. J. Lipid Res 52, 480-488 (2011)
-
(2011)
J. Lipid Res
, vol.52
, pp. 480-488
-
-
Altintas, M.M.1
-
22
-
-
84904044334
-
Adipocyte inflammation is essential for healthy adipose tissue expansion and remodeling
-
Wernstedt Asterholm, I. et al. Adipocyte inflammation is essential for healthy adipose tissue expansion and remodeling. Cell Metab 20, 103-118 (2014)
-
(2014)
Cell Metab
, vol.20
, pp. 103-118
-
-
Wernstedt Asterholm, I.1
-
23
-
-
79751512463
-
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
-
Vandanmagsar, B. et al. The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nature Med. 17, 179-188 (2011)
-
(2011)
Nature Med
, vol.17
, pp. 179-188
-
-
Vandanmagsar, B.1
-
24
-
-
62849107819
-
Metabolic dysregulation and adipose tissue fibrosis: Role of collagen VI
-
Khan, T. et al. Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI. Mol. Cell. Biol. 29, 1575-1591 (2009)
-
(2009)
Mol. Cell. Biol
, vol.29
, pp. 1575-1591
-
-
Khan, T.1
-
25
-
-
0034959752
-
Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein e against atherosclerosis
-
Makowski, L. et al. Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis. Nature Med. 7, 699-705 (2001)
-
(2001)
Nature Med
, vol.7
, pp. 699-705
-
-
Makowski, L.1
-
26
-
-
84874399589
-
Lessons on conditional gene targeting in mouse adipose tissue
-
Lee, K. Y. et al. Lessons on conditional gene targeting in mouse adipose tissue. Diabetes 62, 864-874 (2013)
-
(2013)
Diabetes
, vol.62
, pp. 864-874
-
-
Lee, K.Y.1
-
27
-
-
27444437321
-
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
-
Cinti, S. et al. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J. Lipid Res. 46, 2347-2355 (2005)
-
(2005)
J. Lipid Res
, vol.46
, pp. 2347-2355
-
-
Cinti, S.1
-
28
-
-
80052857420
-
High-fat diet-induced adipocyte cell death occurs through a cyclophilin D intrinsic signaling pathway independent of adipose tissue inflammation
-
Feng, D. et al. High-fat diet-induced adipocyte cell death occurs through a cyclophilin D intrinsic signaling pathway independent of adipose tissue inflammation. Diabetes 60, 2134-2143 (2011)
-
(2011)
Diabetes
, vol.60
, pp. 2134-2143
-
-
Feng, D.1
-
29
-
-
0034845958
-
PKB/Akt: A key mediator of cell proliferation survival and insulin responses?
-
Lawlor, M. A. & Alessi, D. R. PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? J Cell Sci. 114, 2903-2910 (2001)
-
(2001)
J Cell Sci
, vol.114
, pp. 2903-2910
-
-
Lawlor, M.A.1
Alessi, D.R.2
-
30
-
-
33845592201
-
Adipose tissue-derived factors: Impact on health and disease
-
Trujillo, M. E. & Scherer, P. E. Adipose tissue-derived factors: impact on health and disease. Endocrine Rev. 27, 762-778 (2006)
-
(2006)
Endocrine Rev
, vol.27
, pp. 762-778
-
-
Trujillo, M.E.1
Scherer, P.E.2
-
31
-
-
78650065000
-
Identification of the lipid droplet targeting domain of the Cidea protein
-
Christianson, J. L., Boutet, E., Puri, V., Chawla, A. & Czech, M. P. Identification of the lipid droplet targeting domain of the Cidea protein. J. Lipid Res. 51, 3455-3462 (2010)
-
(2010)
J. Lipid Res
, vol.51
, pp. 3455-3462
-
-
Christianson, J.L.1
Boutet, E.2
Puri, V.3
Chawla, A.4
Czech, M.P.5
-
32
-
-
84860201914
-
CIDE proteins and lipid metabolism
-
Xu, L., Zhou, L. & Li, P. CIDE proteins and lipid metabolism. Arterioscler. Thromb. Vasc. Biol. 32, 1094-1098 (2012)
-
(2012)
Arterioscler. Thromb. Vasc. Biol
, vol.32
, pp. 1094-1098
-
-
Xu, L.1
Zhou, L.2
Li, P.3
-
33
-
-
33646462136
-
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase
-
Haemmerle, G. et al. Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science (New York, NY) 312, 734-737 (2006)
-
(2006)
Science (New York, NY
, vol.312
, pp. 734-737
-
-
Haemmerle, G.1
-
34
-
-
84893134937
-
Defective adipose lipolysis and altered global energy metabolism in mice with adipose overexpression of the lipolytic inhibitor G0/G1 switch gene 2 (G0S2
-
Heckmann, B. L. et al. Defective adipose lipolysis and altered global energy metabolism in mice with adipose overexpression of the lipolytic inhibitor G0/G1 switch gene 2 (G0S2). J. Biol. Chem. 289, 1905-1916 (2014)
-
(2014)
J. Biol. Chem
, vol.289
, pp. 1905-1916
-
-
Heckmann, B.L.1
-
35
-
-
77950192925
-
Dysregulation of lipolysis and lipid metabolism in visceral and subcutaneous adipocytes by high-fat diet: Role of ATGL, HSL, and AMPK
-
Gaidhu, M. P., Anthony, N. M., Patel, P., Hawke, T. J. & Ceddia, R. B. Dysregulation of lipolysis and lipid metabolism in visceral and subcutaneous adipocytes by high-fat diet: role of ATGL, HSL, and AMPK. Am. J. Physiol. Cell Physiol. 298, C961-C971 (2010)
-
(2010)
Am. J. Physiol. Cell Physiol
, vol.298
, pp. C961-C971
-
-
Gaidhu, M.P.1
Anthony, N.M.2
Patel, P.3
Hawke, T.J.4
Ceddia, R.B.5
-
36
-
-
9644260361
-
Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice
-
Almind, K. & Kahn, C. R. Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice. Diabetes 53, 3274-3285 (2004)
-
(2004)
Diabetes
, vol.53
, pp. 3274-3285
-
-
Almind, K.1
Kahn, C.R.2
-
37
-
-
3543009434
-
The high-fat diet-fed mouse: A model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes
-
Winzell, M. S. & Ahren, B. The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes. Diabetes 53(Suppl 3)): S215-S219 (2004)
-
(2004)
Diabetes
, vol.53
, pp. S215-S219
-
-
Winzell, M.S.1
Ahren, B.2
-
38
-
-
57349179133
-
Evaluating the glucose tolerance test in mice
-
Andrikopoulos, S., Blair, A. R., Deluca, N., Fam, B. C. & Proietto, J. Evaluating the glucose tolerance test in mice. Am. J. Physiol. 295, E1323-E1332 (2008)
-
(2008)
Am. J. Physiol
, vol.295
, pp. E1323-E1332
-
-
Andrikopoulos, S.1
Blair, A.R.2
Deluca, N.3
Fam, B.C.4
Proietto, J.5
-
39
-
-
82255185902
-
Control of blood glucose in the absence of hepatic glucose production during prolonged fasting in mice: Induction of renal and intestinal gluconeogenesis by glucagon
-
Mutel, E. et al. Control of blood glucose in the absence of hepatic glucose production during prolonged fasting in mice: induction of renal and intestinal gluconeogenesis by glucagon. Diabetes 60, 3121-3131 (2011)
-
(2011)
Diabetes
, vol.60
, pp. 3121-3131
-
-
Mutel, E.1
-
40
-
-
76049099665
-
Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome-an allostatic perspective
-
Virtue, S. & Vidal-Puig, A. Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome-an allostatic perspective. Biochim. Biophys. Acta 1801, 338-349 (2010)
-
(2010)
Biochim. Biophys. Acta 1801
, pp. 338-349
-
-
Virtue, S.1
Vidal-Puig, A.2
-
41
-
-
34848872799
-
Obesity-associated improvements in metabolic profile through expansion of adipose tissue
-
Kim, J. Y. et al. Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J. Clin. Invest. 117, 2621-2637 (2007)
-
(2007)
J. Clin. Invest
, vol.117
, pp. 2621-2637
-
-
Kim, J.Y.1
-
42
-
-
84870302181
-
MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity
-
Kusminski, C. M. et al. MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity. Nature Med. 18, 1539-1549 (2012)
-
(2012)
Nature Med
, vol.18
, pp. 1539-1549
-
-
Kusminski, C.M.1
-
43
-
-
85055501085
-
PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism
-
Medina-Gomez, G. et al. PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism. PLoS Genet. 3, e64 (2007)
-
(2007)
PLoS Genet
, vol.3
, pp. e64
-
-
Medina-Gomez, G.1
-
44
-
-
84891901753
-
Cidea controls lipid droplet fusion and lipid storage in brown and white adipose tissue
-
Wu, L. et al. Cidea controls lipid droplet fusion and lipid storage in brown and white adipose tissue. Science China. Life Sci. 57, 107-116 (2014)
-
(2014)
Science China. Life Sci
, vol.57
, pp. 107-116
-
-
Wu, L.1
-
45
-
-
84883234646
-
Adiponectin, driver or passenger on the road to insulin sensitivity?
-
Ye, R. & Scherer, P. E. Adiponectin, driver or passenger on the road to insulin sensitivity? Mol. Metab. 2, 133-141 (2013)
-
(2013)
Mol. Metab
, vol.2
, pp. 133-141
-
-
Ye, R.1
Scherer, P.E.2
-
46
-
-
84878532462
-
Adipose tissue dysfunction contributes to obesity related metabolic diseases
-
Bluher, M. Adipose tissue dysfunction contributes to obesity related metabolic diseases. Best practice & research. Clin. Endocrinol. Metab. 27, 163-177 (2013)
-
(2013)
Best Practice & Research. Clin. Endocrinol. Metab
, vol.27
, pp. 163-177
-
-
Bluher, M.1
-
47
-
-
34447130417
-
Enhanced proportion of small adipose cells in insulinresistant vs insulin-sensitive obese individuals implicates impaired adipogenesis
-
McLaughlin, T. et al. Enhanced proportion of small adipose cells in insulinresistant vs insulin-sensitive obese individuals implicates impaired adipogenesis. Diabetologia 50, 1707-1715 (2007)
-
(2007)
Diabetologia
, vol.50
, pp. 1707-1715
-
-
McLaughlin, T.1
-
48
-
-
0026080933
-
Identification of a potent adipocyte-specific enhancer: Involvement of an NF-1-like factor
-
Graves, R. A., Tontonoz, P., Ross, S. R. & Spiegelman, B. M. Identification of a potent adipocyte-specific enhancer: involvement of an NF-1-like factor. Genes Dev. 5, 428-437 (1991)
-
(1991)
Genes Dev
, vol.5
, pp. 428-437
-
-
Graves, R.A.1
Tontonoz, P.2
Ross, S.R.3
Spiegelman, B.M.4
-
49
-
-
56449114479
-
Evidence for an important role of CIDEA in human cancer cachexia
-
Laurencikiene, J. et al. Evidence for an important role of CIDEA in human cancer cachexia. Cancer Res. 68, 9247-9254 (2008)
-
(2008)
Cancer Res
, vol.68
, pp. 9247-9254
-
-
Laurencikiene, J.1
-
50
-
-
84865743048
-
Indirect calorimetry in laboratory mice and rats: Principles, practical considerations, interpretation and perspectives
-
Even, P. C. & Nadkarni, N. A. Indirect calorimetry in laboratory mice and rats: principles, practical considerations, interpretation and perspectives. Am.J. Physiol. Regul. Integr. Comp. Physiol. 303, R459-R476 (2012)
-
(2012)
Am.J. Physiol. Regul. Integr. Comp. Physiol
, vol.303
, pp. R459-R476
-
-
Even, P.C.1
Nadkarni, N.A.2
-
51
-
-
0035235089
-
Morphologic techniques for the study of brown adipose tissue and white adipose tissue
-
Cinti, S., Zingaretti, M. C., Cancello, R., Ceresi, E. & Ferrara, P. Morphologic techniques for the study of brown adipose tissue and white adipose tissue. Methods Mol. Biol. 155, 21-51 (2001)
-
(2001)
Methods Mol. Biol
, vol.155
, pp. 21-51
-
-
Cinti, S.1
Zingaretti, M.C.2
Cancello, R.3
Ceresi, E.4
Ferrara, P.5
-
52
-
-
84869012888
-
Adiposoft: Automated software for the analysis of white adipose tissue cellularity in histological sections
-
Galarraga, M. et al. Adiposoft: automated software for the analysis of white adipose tissue cellularity in histological sections. J. Lipid Res. 53, 2791-2796 (2012)
-
(2012)
J. Lipid Res
, vol.53
, pp. 2791-2796
-
-
Galarraga, M.1
-
53
-
-
0021490562
-
Preferential utilization of brown adipose tissue lipids during arousal from hibernation in hamsters
-
Nedergaard, J. & Cannon, B. Preferential utilization of brown adipose tissue lipids during arousal from hibernation in hamsters. Am. J. Physiol. 247, R506-R512 (1984)
-
(1984)
Am. J. Physiol
, vol.247
, pp. R506-R512
-
-
Nedergaard, J.1
Cannon, B.2
|