-
2
-
-
84910037773
-
Overexpression of Collagen Triple Helix Repeat Containing 1 (CTHRC1) is associated with tumour aggressiveness and poor prognosis in human non-small cell lung cancer
-
Ke Z, He W, Lai Y, Guo X, Chen S, Li S, Wang Y and Wang L. Overexpression of Collagen Triple Helix Repeat Containing 1 (CTHRC1) is associated with tumour aggressiveness and poor prognosis in human non-small cell lung cancer. Oncotarget. 2014; 5:9410.
-
(2014)
Oncotarget
, vol.5
, pp. 9410
-
-
Ke, Z.1
He, W.2
Lai, Y.3
Guo, X.4
Chen, S.5
Li, S.6
Wang, Y.7
Wang, L.8
-
3
-
-
84904252059
-
Molecular pathways and therapeutic targets in lung cancer
-
Shtivelman E, Hensing T, Simon GR, Dennis PA, Otterson GA, Bueno R and Salgia R. Molecular pathways and therapeutic targets in lung cancer. Oncotarget. 2014; 5:1392-1433.
-
(2014)
Oncotarget
, vol.5
, pp. 1392-1433
-
-
Shtivelman, E.1
Hensing, T.2
Simon, G.R.3
Dennis, P.A.4
Otterson, G.A.5
Bueno, R.6
Salgia, R.7
-
4
-
-
84915817225
-
Crosstalk between kinases, phosphatases and miRNAs in cancer
-
Abrantes JL, Tornatore TF, Pelizzaro-Rocha KJ, de Jesus MB, Cartaxo RT, Milani R and Ferreira-Halder CV. Crosstalk between kinases, phosphatases and miRNAs in cancer. Biochimie. 2014; 107PB:167-187.
-
(2014)
Biochimie
, vol.107PB
, pp. 167-187
-
-
Abrantes, J.L.1
Tornatore, T.F.2
Pelizzaro-Rocha, K.J.3
de Jesus, M.B.4
Cartaxo, R.T.5
Milani, R.6
Ferreira-Halder, C.V.7
-
5
-
-
84867283479
-
Targeting protein-tyrosine phosphatases in breast cancer
-
Aceto N and Bentires-Alj M. Targeting protein-tyrosine phosphatases in breast cancer. Oncotarget. 2012; 3:514-515.
-
(2012)
Oncotarget
, vol.3
, pp. 514-515
-
-
Aceto, N.1
Bentires-Alj, M.2
-
6
-
-
84866604619
-
Phosphatases: the new brakes for cancer development?
-
Zhang Q and Claret FX. Phosphatases: the new brakes for cancer development? Enzyme Res. 2012; 2012:659649.
-
(2012)
Enzyme Res
, vol.2012
-
-
Zhang, Q.1
Claret, F.X.2
-
7
-
-
84876990097
-
Protein phosphatase 2A: a target for anticancer therapy
-
Perrotti D and Neviani P. Protein phosphatase 2A: a target for anticancer therapy. Lancet Oncol. 2013; 14:e229-238.
-
(2013)
Lancet Oncol
, vol.14
, pp. e229-e238
-
-
Perrotti, D.1
Neviani, P.2
-
8
-
-
1442310493
-
Identification of specific PP2A complexes involved in human cell transformation
-
Chen W, Possemato R, Campbell KT, Plattner CA, Pallas DC and Hahn WC. Identification of specific PP2A complexes involved in human cell transformation. Cancer Cell. 2004; 5:127-136.
-
(2004)
Cancer Cell
, vol.5
, pp. 127-136
-
-
Chen, W.1
Possemato, R.2
Campbell, K.T.3
Plattner, C.A.4
Pallas, D.C.5
Hahn, W.C.6
-
10
-
-
80755153598
-
Low expression of PP2A regulatory subunit B55a is associated with T308 phosphorylation of AKT and shorter complete remission duration in acute myeloid leukemia patients
-
Ruvolo PP, Qui Y, Coombes KR, Zhang N, Ruvolo VR, Borthakur G, Konopleva M, Andreeff M and Kornblau SM. Low expression of PP2A regulatory subunit B55a is associated with T308 phosphorylation of AKT and shorter complete remission duration in acute myeloid leukemia patients. Leukemia. 2011; 25:1711-1717.
-
(2011)
Leukemia
, vol.25
, pp. 1711-1717
-
-
Ruvolo, P.P.1
Qui, Y.2
Coombes, K.R.3
Zhang, N.4
Ruvolo, V.R.5
Borthakur, G.6
Konopleva, M.7
Andreeff, M.8
Kornblau, S.M.9
-
11
-
-
38349190654
-
Regulation of phosphorylation of Thr-308 of Akt, cell proliferation, and survival by the B55alpha regulatory subunit targeting of the protein phosphatase 2A holoenzyme to Akt
-
Kuo YC, Huang KY, Yang CH, Yang YS, Lee WY and Chiang CW. Regulation of phosphorylation of Thr-308 of Akt, cell proliferation, and survival by the B55alpha regulatory subunit targeting of the protein phosphatase 2A holoenzyme to Akt. J Biol Chem. 2008; 283:1882-1892.
-
(2008)
J Biol Chem
, vol.283
, pp. 1882-1892
-
-
Kuo, Y.C.1
Huang, K.Y.2
Yang, C.H.3
Yang, Y.S.4
Lee, W.Y.5
Chiang, C.W.6
-
12
-
-
27744512550
-
Distinct protein phosphatase 2A heterotrimers modulate growth factor signaling to extracellular signal-regulated kinases and Akt
-
Van Kanegan MJ, Adams DG, Wadzinski BE and Strack S. Distinct protein phosphatase 2A heterotrimers modulate growth factor signaling to extracellular signal-regulated kinases and Akt. J Biol Chem. 2005; 280:36029-36036.
-
(2005)
J Biol Chem
, vol.280
, pp. 36029-36036
-
-
Van Kanegan, M.J.1
Adams, D.G.2
Wadzinski, B.E.3
Strack, S.4
-
13
-
-
33644524383
-
B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK
-
Letourneux C, Rocher G and Porteu F. B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK. Embo J. 2006; 25:727-738.
-
(2006)
Embo J
, vol.25
, pp. 727-738
-
-
Letourneux, C.1
Rocher, G.2
Porteu, F.3
-
14
-
-
34447283580
-
CIP2A inhibits PP2A in human malignancies
-
Junttila MR, Puustinen P, Niemela M, Ahola R, Arnold H, Bottzauw T, Ala-aho R, Nielsen C, Ivaska J, Taya Y, Lu SL, Lin S, Chan EK, Wang XJ, Grenman R, Kast J, et al. CIP2A inhibits PP2A in human malignancies. Cell. 2007; 130:51-62.
-
(2007)
Cell
, vol.130
, pp. 51-62
-
-
Junttila, M.R.1
Puustinen, P.2
Niemela, M.3
Ahola, R.4
Arnold, H.5
Bottzauw, T.6
Ala-aho, R.7
Nielsen, C.8
Ivaska, J.9
Taya, Y.10
Lu, S.L.11
Lin, S.12
Chan, E.K.13
Wang, X.J.14
Grenman, R.15
Kast, J.16
-
15
-
-
43049121301
-
A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins
-
Arnold HK and Sears RC. A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins. Cancer Metastasis Rev. 2008; 27(2):147-158.
-
(2008)
Cancer Metastasis Rev
, vol.27
, Issue.2
, pp. 147-158
-
-
Arnold, H.K.1
Sears, R.C.2
-
17
-
-
0035840446
-
Role of serine/threonine protein phosphatase 2A in cancer
-
Schonthal AH. Role of serine/threonine protein phosphatase 2A in cancer. Cancer Lett. 2001; 170(1):1-13.
-
(2001)
Cancer Lett
, vol.170
, Issue.1
, pp. 1-13
-
-
Schonthal, A.H.1
-
18
-
-
84907485878
-
Inhibition of protein phosphatase 2A with a small molecule LB100 radiosensitizes nasopharyngeal carcinoma xenografts by inducing mitotic catastrophe and blocking DNA damage repair
-
Lv P, Wang Y, Ma J, Wang Z, Li JL, Hong CS, Zhuang Z and Zeng YX. Inhibition of protein phosphatase 2A with a small molecule LB100 radiosensitizes nasopharyngeal carcinoma xenografts by inducing mitotic catastrophe and blocking DNA damage repair. Oncotarget. 2014; 5:7512-7524.
-
(2014)
Oncotarget
, vol.5
, pp. 7512-7524
-
-
Lv, P.1
Wang, Y.2
Ma, J.3
Wang, Z.4
Li, J.L.5
Hong, C.S.6
Zhuang, Z.7
Zeng, Y.X.8
-
19
-
-
0029889342
-
The myeloid leukemiaassociated protein SET is a potent inhibitor of protein phosphatase 2A
-
Li M, Makkinje A and Damuni Z. The myeloid leukemiaassociated protein SET is a potent inhibitor of protein phosphatase 2A. Journal of Biological Chemistry. 1996; 271:11059-11062.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 11059-11062
-
-
Li, M.1
Makkinje, A.2
Damuni, Z.3
-
20
-
-
80052259754
-
Mechanism of inhibition of PP2A activity and abnormal hyperphosphorylation of tau by I2(PP2A)/SET
-
Arnaud L, Chen S, Liu F, Li B, Khatoon S, Grundke-Iqbal I and Iqbal K. Mechanism of inhibition of PP2A activity and abnormal hyperphosphorylation of tau by I2(PP2A)/SET. FEBS Lett. 2011; 585:2653-2659.
-
(2011)
FEBS Lett
, vol.585
, pp. 2653-2659
-
-
Arnaud, L.1
Chen, S.2
Liu, F.3
Li, B.4
Khatoon, S.5
Grundke-Iqbal, I.6
Iqbal, K.7
-
21
-
-
0037067661
-
The oncoprotein Set/TAF-1beta, an inhibitor of histone acetyltransferase, inhibits active demethylation of DNA, integrating DNA methylation and transcriptional silencing
-
Cervoni N, Detich N, Seo SB, Chakravarti D and Szyf M. The oncoprotein Set/TAF-1beta, an inhibitor of histone acetyltransferase, inhibits active demethylation of DNA, integrating DNA methylation and transcriptional silencing. J Biol Chem. 2002; 277:25026-25031.
-
(2002)
J Biol Chem
, vol.277
, pp. 25026-25031
-
-
Cervoni, N.1
Detich, N.2
Seo, S.B.3
Chakravarti, D.4
Szyf, M.5
-
22
-
-
1242329866
-
Effects of SET and SET-CAN on the differentiation of the human promonocytic cell line U937
-
Kandilci A, Mientjes E and Grosveld G. Effects of SET and SET-CAN on the differentiation of the human promonocytic cell line U937. Leukemia. 2004; 18:337-340.
-
(2004)
Leukemia
, vol.18
, pp. 337-340
-
-
Kandilci, A.1
Mientjes, E.2
Grosveld, G.3
-
23
-
-
84896733638
-
Accumulated SET protein up-regulates and interacts with hnRNPK, increasing its binding to nucleic acids, the Bcl-xS repression, and cellular proliferation
-
Almeida LO, Garcia CB, Matos-Silva FA, Curti C and Leopoldino AM. Accumulated SET protein up-regulates and interacts with hnRNPK, increasing its binding to nucleic acids, the Bcl-xS repression, and cellular proliferation. Biochem Biophys Res Commun. 2014; 445:196-202.
-
(2014)
Biochem Biophys Res Commun
, vol.445
, pp. 196-202
-
-
Almeida, L.O.1
Garcia, C.B.2
Matos-Silva, F.A.3
Curti, C.4
Leopoldino, A.M.5
-
24
-
-
84873840846
-
SET protein interacts with intracellular domains of the gonadotropin-releasing hormone receptor and differentially regulates receptor signaling to cAMP and calcium in gonadotrope cells
-
Avet C, Garrel G, Denoyelle C, Laverriere JN, Counis R, Cohen-Tannoudji J and Simon V. SET protein interacts with intracellular domains of the gonadotropin-releasing hormone receptor and differentially regulates receptor signaling to cAMP and calcium in gonadotrope cells. J Biol Chem. 2013; 288:2641-2654.
-
(2013)
J Biol Chem
, vol.288
, pp. 2641-2654
-
-
Avet, C.1
Garrel, G.2
Denoyelle, C.3
Laverriere, J.N.4
Counis, R.5
Cohen-Tannoudji, J.6
Simon, V.7
-
25
-
-
84921059747
-
Deregulation of the PP2A Inhibitor SET Shows Promising Therapeutic Implications and Determines Poor Clinical Outcome in Patients with Metastatic Colorectal Cancer
-
Cristobal I, Rincon R, Manso R, Carames C, Zazo S, Madoz-Gurpide J, Rojo F and Garcia-Foncillas J. Deregulation of the PP2A Inhibitor SET Shows Promising Therapeutic Implications and Determines Poor Clinical Outcome in Patients with Metastatic Colorectal Cancer. Clin Cancer Res. 2015; 21:347-356.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 347-356
-
-
Cristobal, I.1
Rincon, R.2
Manso, R.3
Carames, C.4
Zazo, S.5
Madoz-Gurpide, J.6
Rojo, F.7
Garcia-Foncillas, J.8
-
26
-
-
84859449771
-
Overexpression of SET is a recurrent event associated with poor outcome and contributes to protein phosphatase 2A inhibition in acute myeloid leukemia
-
Cristóbal I, Garcia-Orti L, Cirauqui C, Cortes-Lavaud X, García-Sánchez MA, Calasanz MJ and Odero MD. Overexpression of SET is a recurrent event associated with poor outcome and contributes to protein phosphatase 2A inhibition in acute myeloid leukemia. Haematologica. 2012; 97:543-550.
-
(2012)
Haematologica
, vol.97
, pp. 543-550
-
-
Cristóbal, I.1
Garcia-Orti, L.2
Cirauqui, C.3
Cortes-Lavaud, X.4
García-Sánchez, M.A.5
Calasanz, M.J.6
Odero, M.D.7
-
27
-
-
84867858444
-
SET protein accumulates in HNSCC and contributes to cell survival: Antioxidant defense, Akt phosphorylation and AVOs acidification
-
Leopoldino AM, Squarize CH, Garcia CB, Almeida LO, Pestana CR, Sobral LM, Uyemura SA, Tajara EH, Silvio Gutkind J and Curti C. SET protein accumulates in HNSCC and contributes to cell survival: Antioxidant defense, Akt phosphorylation and AVOs acidification. Oral oncology. 2012; 48:1106-1113.
-
(2012)
Oral oncology
, vol.48
, pp. 1106-1113
-
-
Leopoldino, A.M.1
Squarize, C.H.2
Garcia, C.B.3
Almeida, L.O.4
Pestana, C.R.5
Sobral, L.M.6
Uyemura, S.A.7
Tajara, E.H.8
Silvio Gutkind, J.9
Curti, C.10
-
28
-
-
84903449080
-
Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer
-
Janghorban M, Farrell AS, Allen-Petersen BL, Pelz C, Daniel CJ, Oddo J, Langer EM, Christensen DJ and Sears RC. Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer. Proc Natl Acad Sci U S A. 2014; 111:9157-9162.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 9157-9162
-
-
Janghorban, M.1
Farrell, A.S.2
Allen-Petersen, B.L.3
Pelz, C.4
Daniel, C.J.5
Oddo, J.6
Langer, E.M.7
Christensen, D.J.8
Sears, R.C.9
-
29
-
-
84907609978
-
SET-mediated NDRG1 inhibition is involved in acquisition of epithelial-to-mesenchymal transition phenotype and cisplatin resistance in human lung cancer cell
-
Liu H, Gu Y, Yin J, Zheng G, Wang C, Zhang Z, Deng M, Liu J, Jia X and He Z. SET-mediated NDRG1 inhibition is involved in acquisition of epithelial-to-mesenchymal transition phenotype and cisplatin resistance in human lung cancer cell. Cell Signal. 2014; 26:2710-2720.
-
(2014)
Cell Signal
, vol.26
, pp. 2710-2720
-
-
Liu, H.1
Gu, Y.2
Yin, J.3
Zheng, G.4
Wang, C.5
Zhang, Z.6
Deng, M.7
Liu, J.8
Jia, X.9
He, Z.10
-
30
-
-
84896720465
-
Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor models
-
Sobral LM, Sousa LO, Coletta RD, Cabral H, Greene LJ, Tajara EH, Gutkind JS, Curti C and Leopoldino AM. Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor models. Mol Cancer. 2014; 13:32.
-
(2014)
Mol Cancer
, vol.13
, pp. 32
-
-
Sobral, L.M.1
Sousa, L.O.2
Coletta, R.D.3
Cabral, H.4
Greene, L.J.5
Tajara, E.H.6
Gutkind, J.S.7
Curti, C.8
Leopoldino, A.M.9
-
31
-
-
84924274839
-
PP2A inhibition determines poor outcome and doxorubicin resistance in early breast cancer and its activation shows promising therapeutic effects
-
Rincon R, Cristobal I, Zazo S, Arpi O, Menendez S, Manso R, Lluch A, Eroles P, Rovira A, Albanell J, Garcia-Foncillas J, Madoz-Gurpide J and Rojo F. PP2A inhibition determines poor outcome and doxorubicin resistance in early breast cancer and its activation shows promising therapeutic effects. Oncotarget. 2015; 6:4299-4314.
-
(2015)
Oncotarget
, vol.6
, pp. 4299-4314
-
-
Rincon, R.1
Cristobal, I.2
Zazo, S.3
Arpi, O.4
Menendez, S.5
Manso, R.6
Lluch, A.7
Eroles, P.8
Rovira, A.9
Albanell, J.10
Garcia-Foncillas, J.11
Madoz-Gurpide, J.12
Rojo, F.13
-
32
-
-
27644569730
-
The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein
-
Neviani P, Santhanam R, Trotta R, Notari M, Blaser BW, Liu S, Mao H, Chang JS, Galietta A and Uttam A. The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein. Cancer cell. 2005; 8:355-368.
-
(2005)
Cancer cell
, vol.8
, pp. 355-368
-
-
Neviani, P.1
Santhanam, R.2
Trotta, R.3
Notari, M.4
Blaser, B.W.5
Liu, S.6
Mao, H.7
Chang, J.S.8
Galietta, A.9
Uttam, A.10
-
33
-
-
84887391984
-
Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies
-
Oaks JJ, Santhanam R, Walker CJ, Roof S, Harb JG, Ferenchak G, Eisfeld AK, Van Brocklyn JR, Briesewitz R, Saddoughi SA, Nagata K, Bittman R, Caligiuri MA, Abdel-Wahab O, Levine R, Arlinghaus RB, et al. Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies. Blood. 2013; 122:1923-1934.
-
(2013)
Blood
, vol.122
, pp. 1923-1934
-
-
Oaks, J.J.1
Santhanam, R.2
Walker, C.J.3
Roof, S.4
Harb, J.G.5
Ferenchak, G.6
Eisfeld, A.K.7
Van Brocklyn, J.R.8
Briesewitz, R.9
Saddoughi, S.A.10
Nagata, K.11
Bittman, R.12
Caligiuri, M.A.13
Abdel-Wahab, O.14
Levine, R.15
Arlinghaus, R.B.16
-
34
-
-
84871968824
-
Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis
-
Saddoughi SA, Gencer S, Peterson YK, Ward KE, Mukhopadhyay A, Oaks J, Bielawski J, Szulc ZM, Thomas RJ, Selvam SP, Senkal CE, Garrett-Mayer E, De Palma RM, Fedarovich D, Liu A, Habib AA, et al. Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis. EMBO Mol Med. 2013; 5:105-121.
-
(2013)
EMBO Mol Med
, vol.5
, pp. 105-121
-
-
Saddoughi, S.A.1
Gencer, S.2
Peterson, Y.K.3
Ward, K.E.4
Mukhopadhyay, A.5
Oaks, J.6
Bielawski, J.7
Szulc, Z.M.8
Thomas, R.J.9
Selvam, S.P.10
Senkal, C.E.11
Garrett-Mayer, E.12
De Palma, R.M.13
Fedarovich, D.14
Liu, A.15
Habib, A.A.16
-
35
-
-
79957910918
-
Targeting SET/I2PP2A oncoprotein functions as a multi-pathway strategy for cancer therapy
-
Switzer CH, Cheng RY, Vitek TM, Christensen DJ, Wink DA and Vitek MP. Targeting SET/I2PP2A oncoprotein functions as a multi-pathway strategy for cancer therapy. Oncogene. 2011; 30:2504-2513.
-
(2011)
Oncogene
, vol.30
, pp. 2504-2513
-
-
Switzer, C.H.1
Cheng, R.Y.2
Vitek, T.M.3
Christensen, D.J.4
Wink, D.A.5
Vitek, M.P.6
-
36
-
-
31544447428
-
Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization
-
LaMontagne K, Littlewood-Evans A, Schnell C, O'Reilly T, Wyder L, Sanchez T, Probst B, Butler J, Wood A, Liau G, Billy E, Theuer A, Hla T and Wood J. Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization. Cancer Res. 2006; 66:221-231.
-
(2006)
Cancer Res
, vol.66
, pp. 221-231
-
-
LaMontagne, K.1
Littlewood-Evans, A.2
Schnell, C.3
O'Reilly, T.4
Wyder, L.5
Sanchez, T.6
Probst, B.7
Butler, J.8
Wood, A.9
Liau, G.10
Billy, E.11
Theuer, A.12
Hla, T.13
Wood, J.14
-
37
-
-
84878431342
-
Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer
-
Seshacharyulu P, Pandey P, Datta K and Batra SK. Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer. Cancer Lett. 2013; 335:9-18.
-
(2013)
Cancer Lett
, vol.335
, pp. 9-18
-
-
Seshacharyulu, P.1
Pandey, P.2
Datta, K.3
Batra, S.K.4
-
38
-
-
0032500792
-
Alterations of the PPP2R1B gene in human lung and colon cancer
-
Wang SS, Esplin ED, Li JL, Huang L, Gazdar A, Minna J and Evans GA. Alterations of the PPP2R1B gene in human lung and colon cancer. Science. 1998; 282(5387):284-287.
-
(1998)
Science
, vol.282
, Issue.5387
, pp. 284-287
-
-
Wang, S.S.1
Esplin, E.D.2
Li, J.L.3
Huang, L.4
Gazdar, A.5
Minna, J.6
Evans, G.A.7
-
39
-
-
0035810043
-
Alterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the A beta subunit gene
-
Ruediger R, Pham HT and Walter G. Alterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the A beta subunit gene. Oncogene. 2001; 20:1892-1899.
-
(2001)
Oncogene
, vol.20
, pp. 1892-1899
-
-
Ruediger, R.1
Pham, H.T.2
Walter, G.3
-
40
-
-
80052590060
-
Human cancer-associated mutations in the Aalpha subunit of protein phosphatase 2A increase lung cancer incidence in Aalpha knock-in and knockout mice
-
Ruediger R, Ruiz J and Walter G. Human cancer-associated mutations in the Aalpha subunit of protein phosphatase 2A increase lung cancer incidence in Aalpha knock-in and knockout mice. Mol Cell Biol. 2011; 31:3832-3844.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 3832-3844
-
-
Ruediger, R.1
Ruiz, J.2
Walter, G.3
-
41
-
-
84908300167
-
Effect of FTY720 on the SET-PP2A complex in acute myeloid leukemia; SET binding drugs have antagonistic activity
-
Pippa R, Dominguez A, Christensen DJ, Moreno-Miralles I, Blanco-Prieto MJ, Vitek MP and Odero MD. Effect of FTY720 on the SET-PP2A complex in acute myeloid leukemia; SET binding drugs have antagonistic activity. Leukemia. 2014; 28:1915-1918.
-
(2014)
Leukemia
, vol.28
, pp. 1915-1918
-
-
Pippa, R.1
Dominguez, A.2
Christensen, D.J.3
Moreno-Miralles, I.4
Blanco-Prieto, M.J.5
Vitek, M.P.6
Odero, M.D.7
-
42
-
-
34648832173
-
FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia
-
Neviani P, Santhanam R, Oaks JJ, Eiring AM, Notari M, Blaser BW, Liu S, Trotta R, Muthusamy N, Gambacorti-Passerini C, Druker BJ, Cortes J, Marcucci G, Chen CS, Verrills NM, Roy DC, et al. FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia. J Clin Invest. 2007; 117:2408-2421.
-
(2007)
J Clin Invest
, vol.117
, pp. 2408-2421
-
-
Neviani, P.1
Santhanam, R.2
Oaks, J.J.3
Eiring, A.M.4
Notari, M.5
Blaser, B.W.6
Liu, S.7
Trotta, R.8
Muthusamy, N.9
Gambacorti-Passerini, C.10
Druker, B.J.11
Cortes, J.12
Marcucci, G.13
Chen, C.S.14
Verrills, N.M.15
Roy, D.C.16
-
43
-
-
84899000071
-
SETting OP449 into the PP2AActivating Drug Family
-
Neviani P and Perrotti D. SETting OP449 into the PP2AActivating Drug Family. Clin Cancer Res. 2014; 20:2026-2028.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 2026-2028
-
-
Neviani, P.1
Perrotti, D.2
-
44
-
-
84902676509
-
Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancer
-
Farrell AS, Allen-Petersen B, Daniel CJ, Wang X, Wang Z, Rodriguez S, Impey S, Oddo J, Vitek MP, Lopez C, Christensen DJ, Sheppard B and Sears RC. Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancer. Mol Cancer Res. 2014; 12:924-939.
-
(2014)
Mol Cancer Res
, vol.12
, pp. 924-939
-
-
Farrell, A.S.1
Allen-Petersen, B.2
Daniel, C.J.3
Wang, X.4
Wang, Z.5
Rodriguez, S.6
Impey, S.7
Oddo, J.8
Vitek, M.P.9
Lopez, C.10
Christensen, D.J.11
Sheppard, B.12
Sears, R.C.13
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