Treatment with serotonin reuptake inhibitors during pregnancy is associated with elevated corticotropin-releasing hormone levels

Psychoneuroendocrinology

Volumn 58, Issue 1, 2015, Pages 104-113

  Hannerfors, A K ^a   Hellgren, C ^a   Schijven, D ^a   Iliadis, S I ^a   Comasco, E ^a   Skalkidou, A ^a   Olivier, J D A ^a,b   Sundstrom Poromaa I ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Corticotropin releasing hormone; Depression; Gestational length; Pregnancy; Preterm birth; Serotonin reuptake inhibitor

Indexed keywords

CITALOPRAM; CORTICOTROPIN RELEASING FACTOR; ESCITALOPRAM; FLUOXETINE; PAROXETINE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE;

ADULT; ARTICLE; CONTROLLED STUDY; DEPRESSION; DISEASE ASSOCIATION; FEMALE; GESTATIONAL AGE; HORMONE BLOOD LEVEL; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; PREGNANCY; PREGNANT WOMAN; PREMATURE LABOR; PRIORITY JOURNAL; RISK ASSESSMENT; SECOND TRIMESTER PREGNANCY; BLOOD; DEPRESSIVE DISORDER; MENTAL STRESS; THIRD TRIMESTER PREGNANCY; YOUNG ADULT;

ADULT; CORTICOTROPIN-RELEASING HORMONE; DEPRESSIVE DISORDER; FEMALE; HUMANS; PREGNANCY; PREGNANCY TRIMESTER, SECOND; PREGNANCY TRIMESTER, THIRD; SEROTONIN UPTAKE INHIBITORS; STRESS, PSYCHOLOGICAL; YOUNG ADULT;

EID: 84933526654     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2015.04.009     Document Type: Article

References (50)

1. Alwan, S., Reefhuis, J., Rasmussen, S.A., Friedman, J.M., 2011. Patterns of antidepressant medication use among pregnant women in a United States population. J. Clin. Pharmacol. 51, 264-270.
2. Andersson, L, Sundstrom-Poromaa, I., Bixo, M., Wulff, M., Bondestam, K., Åstrom, M., 2003. Point prevalence of psychiatric disorders during the second trimester of pregnancy: a population-based study. Am. J. Obstet. Gynecol. 189, 148-154.
3. Bjerkenstedt, L, Flyckt, L, Overo, K.F., Lingjaerde, O., 1985. Relationship between clinical effects, serum drug concentration and serotonin uptake inhibition in depressed patients treated with citalopram. A double-blind comparison of three dose levels. Eur. J. Clin. Pharmacol. 28, 553-557.
4. Campbell, E.A., Linton, E.A., Wolfe, CD., Scraggs, P.R., Jones, M.T., Lowry, P.J., 1987. Plasma corticotropin-releasing hormone concentrations during pregnancy and parturition. J. Clin. Endocrinol. Metab. 64, 1054-1059.
5. Chen, Y Holzman, C, Chung, H., Senagore, P., Talge, N.M., Siler-Khodr, T, 2010. Levels of maternal serum corticotropin-releasing hormone (CRH) at midpregnancy in relation to maternal characteristics. Psychoneuroendocrinology 35, 820-832.
6. Cnattingius, S., Villamor, E., Johansson, S., Edstedt Bonamy, A.K., Persson, M., Wikstrom, A.K., Granath, F., 2013. Maternal obesity and risk of preterm delivery. J. Am. Med. Assoc. 309, 2362-2370.
7. Cox, J.L., Holden, J.M., Sagovsky, R., 1987. Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale. Br. J. Psychiatry 150, 782-786.
8. Freeman, M.P., Nolan Jr., P.E., Davis, M.F., Anthony, M., Fried, K., Fankhauser, M., Woosley, R.L, Moreno, F., 2008. Pharmacokinetics of sertraline across pregnancy and postpartum. J. Clin. Psychopharmacol. 28, 646-653.
9. Gavin, N.I., Gaynes, B.N., Lohr, K.N., Meltzer-Brody, S., Gartlehner, G., Swinson, T, 2005. Perinatal depression: a systematic review of prevalence and incidence. Obstet. Gynecol. 106, 1071-1083.
10. Giles, W.B., McLean, M., Davies, J.J., Smith, R., 1996. Abnormal umbilical artery Doppler waveforms and cord blood corticotropin-releasing hormone. Obstet. Gynecol. 87,107-111.
11. Goland, R.S., Jozak, S., Warren, W.B., Conwell, I.M., Stark, R.I., Tropper, P.J., 1993. Elevated levels of umbilical cord plasma corticotropin-releasing hormone in growth-retarded fetuses. J. Clin. Endocrinol. Metab. 77, 1174-1179.
12. Goland, R.S., Wardlaw, S.L., Stark, R.I., Brown Jr., L.S., Frantz, A.G., 1986. High levels of corticotropin-releasing hormone immunoactivity in maternal and fetal plasma during pregnancy. J. Clin. Endocrinol. Metab. 63, 1199-1203.
13. Granfors, M., Akerud, H., Berglund, A., Skogo, J., Sundstrom-Poromaa, I., Wikstrom, A.K., 2013. Thyroid testing and management of hypothyroidism during pregnancy; A population based study. J. Clin. Endocrinol. Metab. 98, 2687-2692.
14. Grote, N.K., Bridge, J.A., Gavin, A.R., Melville, J.L., Iyengar, S., Katon, W.J., 2010. A meta-analysis of depression during pregnancy and the risk of preterm birth, low birth weight, and intrauterine growth restriction. Arch. Gen. Psychiatry 67, 1012-1024.
15. Guendelman, S., Kosa, J.L., Pearl, M., Graham, S., Kharrazi, M., 2008. Exploring the relationship of second-trimester corticotropin releasing hormone, chronic stress and preterm delivery. J. Matern. Fetal Neonatal Med. 21, 788-795.
16. Harville, E.W., Savitz, D.A., Dole, N., Herring, A.H., Thorp, J.M., 2009. Stress questionnaires and stress biomarkers during pregnancy. J. Women's Health (Larchmt) 18, 1425-1433.
17. Hendrick, V., Stowe, Z.N., Altshuler, L.L., Hwang, S., Lee, E., Haynes, D., 2003. Placental passage of antidepressant medications. Am. J. Psychiatry 160, 993-996.
18. Hill, J.L., Campbell, M.K., Zou, G.Y., Challis, J.R., Reid, G., Chisaka, H., Bocking, A.D., 2008. Prediction of preterm birth in symptomatic women using decision tree modeling for biomarkers. Am. J. Obstet. Gynecol. 198 (468), e1-e7 (discussion 468 e7-9).
19. Himes, K.P., Simhan, H.N., 2011. Plasma corticotropin-releasing hormone and cortisol concentrations and perceived stress among pregnant women with preterm and term birth. Am. J. Perinatol. 28, 443-448.
20. Hobel, C.J., Arora, C.P., Korst, L.M., 1999. Corticotrophin-releasing hormone and CRH-binding protein. Differences between patients at risk for preterm birth and hypertension. Ann. N. Y Acad. Sci. 897, 54-65.
21. Holzman, C, Jetton, J., Siler-Khodr, T Fisher, R., Rip, T, 2001. Second trimester corticotropin-releasing hormone levels in relation to preterm delivery and ethnicity. Obstet. Gynecol. 97, 657-663.
22. Inder, W.J., Prickett, T.C., Ellis, M.J., Hull, L., Reid, R., Benny, P.S., Livesey, J.H., Donald, R.A., 2001. The utility of plasma CRH as a predictor of preterm delivery. J. Clin. Endocrinol. Metab. 86, 5706-5710.
23. Kaihola, H., Olivier, J., Poromaa, I.S., Akerud, H., 2015. The effect of antenatal depression and selective serotonin reuptake inhibitor treatment on nerve growth factor signaling in human placenta. PLoS One 10, e0116459.
24. Kieler, H., Artama, M., Engeland, A., Ericsson, O., Furu, K., Gissler, M., Nielsen, R.B., Norgaard, M., Stephansson, O., Valdimarsdottir, U., Zoega, H., Haglund, B., 2012. Selective serotonin reuptake inhibitors during pregnancy and risk of persistent pulmonary hypertension in the newborn: population based cohort study from the five Nordic countries. Br. Med. J. 344, d8012.
25. Kramer, M.S., Lydon, J., Seguin, L., Goulet, L., Kahn, S.R., McNamara, H., Genest, J., Dassa, C, Chen, M.F., Sharma, S., Meaney, M.J., Thomson, S., Van Uum, S., Koren, G., Dahhou, M., Lamoureux, J., Platt, R.W., 2009. Stress pathways to spontaneous preterm birth: the role of stressors, psychological distress, and stress hormones. Am. J. Epidemiol. 169, 1319-1326.
26. Latendresse, G., Ruiz, R.J., 2008. Bioassay research methodology: measuring CRH in pregnancy. Biol. Res. Nurs. 10, 54-62.
27. Latendresse, G., Ruiz, R.J., 2011. Maternal corticotropin-releasing hormone and the use of selective serotonin reuptake inhibitors independently predict the occurrence of preterm birth. J. Midwifery Women's Health 56, 118-126.
28. Leung, T.N., Chung, T.K., Madsen, G., McLean, M., Chang, A.M., Smith, R., 1999. Elevated mid-trimester maternal corticotrophin-releasing hormone levels in pregnancies that delivered before 34 weeks. Br. J. Obstet. Gynaecol. 106, 1041-1046.
29. Mancuso, R.A., Schetter, CD., Rini, CM., Roesch, S.C, Hobel, C.J., 2004. Maternal prenatal anxiety and corticotropin-releasing hormone associated with timing of delivery. Psychosom. Med. 66, 762-769.
30. McLean, M., Bisits, A., Davies, J., Woods, R., Lowry, P., Smith, R., 1995. A placental clock controlling the length of human pregnancy. Nat. Med. 1, 460-463.
31. Meltzer-Brody, S., Stuebe, A., Dole, N., Savitz, D., Rubinow, D., Thorp, J., 2011. Elevated corticotropin releasing hormone (CRH) during pregnancy and risk of postpartum depression (PPD). J. Clin. Endocrinol. Metab. 96, E40-E47.
32. Myles, N., Newall, H., Ward, H., Large, M., 2013. Systematic metaanalysis of individual selective serotonin reuptake inhibitor medications and congenital malformations. Aust. N. Z. J. Psychiatry 47, 1002-1012.
33. NICE guidelines [CG 192], in press. Antenatal and postnatal mental health: clinical management and service guidance, (https://www.nice.org.uk/guidance/cg192).
34. O'Keane, V., Lightman, S., Marsh, M., Pawlby, S., Papadopoulos, A.S., Taylor, A., Moore, R., Patrick, K., 2011. Increased pituitary-adrenal activation and shortened gestation in a sample of depressed pregnant women: a pilot study. J. Affect. Disord. 130, 300-305.
35. Olivier, J.D., Akerud, H., Kaihola, H., Pawluski, J.L., Skalkidou, A., Hogberg, U., Sundstrom-Poromaa, I., 2013. The effects of maternal depression and maternal selective serotonin reuptake inhibitor exposure on offspring. Front. Cell Neurosci. 7, 73.
36. Olivier, J.D., Akerud, H., Skalkidou, A., Kaihola, H., Sundstrom-Poromaa, I., 2014. The effects of antenatal depression and antidepressant treatment on placental gene expression. Front. Cell Neurosci. 8, 465.
37. Perkins, A.V., Linton, E.A., Eben, F. Simpson, J., Wolfe, CD., Redman, C.W., 1995. Corticotrophin-releasing hormone and corticotrophin-releasing hormone binding protein in normal and pre-eclamptic human pregnancies. Br. J. Obstet. Gynaecol. 102, 118-122.
38. Petraglia, F., Imperatore, A., Challis, J.R., 2010. Neuroendocrine mechanisms in pregnancy and parturition. Endocr. Rev. 31, 783-816.
39. Rich-Edwards, J.W., Mohllajee, A.P., Kleinman, K., Hacker, M.R., Majzoub, J., Wright, R.J., Gillman, M.W., 2008. Elevated midpregnancy corticotropin-releasing hormone is associated with prenatal, but not postpartum, maternal depression. J. Clin. Endocrinol. Metab. 93, 1946-1951.
40. Robinson, B.G., Emanuel, R.L., Frim, D.M., Majzoub, J.A., 1988. Glucocorticoid stimulates expression of corticotropin-releasing hormone gene in human placenta. Proc. Natl. Acad. Sci. U. S. A. 85, 5244-5248.
41. Rubertsson, C, Borjesson, K., Berglund, A., Josefsson, A., Sydsjo, G., 2011. The Swedish validation of Edinburgh postnatal depression scale (EPDS) during pregnancy. Nord. J. Psychiatry 65, 414-418.
42. Sasaki, A., Shinkawa, O., Margioris, A.N., Liotta, A.S., Sato, S., Murakami, O., Go, M., Shimizu, Y Hanew, K., Yoshinaga, K., 1987. Immunoreactive corticotropin-releasing hormone in human plasma during pregnancy, labor, and delivery. J. Clin. Endocrinol. Metab. 64, 224-229.
43. Schmeelk, K.H., Granger, D.A., Susman, E.J., Chrousos, G.P., 1999. Maternal depression and risk for postpartum complications: role of prenatal corticotropin-releasing hormone and interleukin-1 receptor antagonist. Behav. Med. 25, 88-94.
44. Sibai, B., Meis, P.J., Klebanoff, M., Dombrowski, M.P., Weiner, S.J., Moawad, A.H., Northen, A., Iams, J.D., Varner, M.W., Caritis, S.N., O'Sullivan, M.J., Miodovnik, M., Leveno, K.J., Conway, D., Wapner, R.J., Carpenter, M., Mercer, B., Ramin, S.M., Thorp Jr., J.M., Peaceman, A.M., Gabbe, S., 2005. Plasma CRH measurement at 16 to 20 weeks' gestation does not predict preterm delivery in women at high-risk for preterm delivery. Am. J. Obstet. Gynecol. 193, 1181-1186.
45. Smith, R., Nicholson, R.C., 2007. Corticotrophin releasing hormone and the timing of birth. Front. Biosci. 12, 912-918.
46. Smith, R., Smith, J.I., Shen, X., Engel, P.J., Bowman, M.E., McGrath, S.A., Bisits, A.M., McElduff, P., Giles, W.B., Smith, D.W., 2009. Patterns of plasma corticotropin-releasing hormone, progesterone, estradiol, and estriol change and the onset of human labor. J. Clin. Endocrinol. Metab. 94, 2066-2074.
47. Susman, E.J., Schmeelk, K.H., Worrall, B.K., Granger, D.A., Ponirakis, A., Chrousos, G.P., 1999. Corticotropin-releasing hormone and cortisol: longitudinal associations with depression and antisocial behavior in pregnant adolescents. J. Am. Acad. Child Adolesc. Psychiatry 38, 460-467.
48. Tse, A.C., Rich-Edwards, J.W., Koenen, K., Wright, R.J., 2012. Cumulative stress and maternal prenatal corticotropin-releasing hormone in an urban U.S. cohort. Psychoneuroendocrinology 37, 970-979.
49. Ververs, T Kaasenbrood, H., Visser, G., Schobben, F, de Jongvan den Berg, L, Egberts, T 2006. Prevalence and patterns of antidepressant drug use during pregnancy. Eur. J. Clin. Pharmacol. 62, 863-870.
50. Yim, I.S., Glynn, L.M., Dunkel-Schetter, C, Hobel, C.J., Chicz-DeMet, A., Sandman, C.A., 2009. Risk of postpartum depressive symptoms with elevated corticotropin-releasing hormone in human pregnancy. Arch. Gen. Psychiatry 66, 162-169.