Human ABCB1 confers cells resistance to cytotoxic guanidine alkaloids from Pterogyne nitens

Bio-Medical Materials and Engineering

Volumn 25, Issue 3, 2015, Pages 249-256

  Satake, Kazuhiro ^a   Tsukamoto, Megumi ^a   Mitani, Yuji ^a   Regasini, Luis Octavio ^b   Bolzani, Vanderlan Da Silva ^b   Efferth, Thomas ^c   Nakagawa, Hiroshi ^a  

^a CHUBU UNIVERSITY   (Japan)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

ABCB1; ATP binding cassette (ABC) transporter; guanidine alkaloids; P glycoprotein

Indexed keywords

ALKALOIDS; CELLS; CHEMOTHERAPY; GLYCOPROTEINS;

ABCB1; ATP BINDING CASSETTE TRANSPORTERS; ATP-ASE ACTIVITY; CYTOTOXIC EFFECTS; GUANIDINE ALKALOIDS; MULTIDRUG RESISTANCE; P-GLYCOPROTEIN; VINBLASTINE;

CYTOLOGY;

ADENOSINE TRIPHOSPHATASE; ALKALOID DERIVATIVE; GALEGINE; GUANIDINE DERIVATIVE; MULTIDRUG RESISTANCE PROTEIN 1; NITENSIDINE A; PACLITAXEL; PTEROGYNIDINE; PTEROGYNINE; UNCLASSIFIED DRUG; VINBLASTINE; ABCB1 PROTEIN, HUMAN; ALKALOID; CYTOTOXIN; MULTIDRUG RESISTANCE PROTEIN;

ARTICLE; ATPASE ACTIVITY ASSAY; CANCER CELL; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MTT ASSAY; PLANT; PRIORITY JOURNAL; PTEROGYNE NITENS; XTT ASSAY; CAESALPINIA; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; METABOLISM; MULTIDRUG RESISTANCE; PHYSIOLOGY;

PTEROGYNE NITENS;

ALKALOIDS; CAESALPINIA; CELL SURVIVAL; CYTOTOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE; GUANIDINES; HEK293 CELLS; HUMANS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEINS;

EID: 84932629440     PISSN: 09592989     EISSN: 18783619     Source Type: Journal    
DOI: 10.3233/BME-151282     Document Type: Article

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