Neutrophil-lymphocyte ratio is associated with arterial stiffness in postmenopausal women with osteoporosis

Archives of Gerontology and Geriatrics

Volumn 61, Issue 1, 2015, Pages 76-80

  Yu, Xin yang ^a   Li, Xue song ^a   Li, Ying ^a   Liu, Tiemin ^b   Wang, Rui tao ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Arterial stiffness; Brachial ankle pulse wave velocity; Inflammation; Neutrophil lymphocyte ratio; Osteoporosis

Indexed keywords

AGED; ARTERIAL STIFFNESS; ARTICLE; BLOOD PRESSURE MEASUREMENT; BODY MASS; BONE DENSITY; BRACHIAL ANKLE PULSE WAVE VELOCITY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; NEUTROPHIL LYMPHOCYTE RATIO; OSTEOPOROSIS; POSTMENOPAUSE; PRIORITY JOURNAL; PULSE WAVE; ANKLE BRACHIAL INDEX; ATHEROSCLEROSIS; BLOOD; BLOOD FLOW VELOCITY; COMPLICATION; LYMPHOCYTE; NEUTROPHIL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; POSTMENOPAUSE OSTEOPOROSIS; RISK FACTOR;

AGED; ANKLE BRACHIAL INDEX; ATHEROSCLEROSIS; BLOOD FLOW VELOCITY; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; LYMPHOCYTES; NEUTROPHILS; OSTEOPOROSIS, POSTMENOPAUSAL; PULSE WAVE ANALYSIS; RISK FACTORS; VASCULAR STIFFNESS;

EID: 84931577946     PISSN: 01674943     EISSN: 18726976     Source Type: Journal    
DOI: 10.1016/j.archger.2015.03.011     Document Type: Article

References (44)

1. Anagnostis P., Karagiannis A., Kakafika A.I., Tziomalos K., Athyros V.G., Mikhailidis D.P. Atherosclerosis and osteoporosis: Age-dependent degenerative processes or related entities. Osteoporosis International 2009, 20:197-207.
2. Arbel Y., Finkelstein A., Halkin A., Birati E.Y., Revivo M., Zuzut M., et al. Neutrophil/lymphocyte ratio is related to the severity of coronary artery disease and clinical outcome in patients undergoing angiography. Atherosclerosis 2012, 225:456-460.
3. Balta S., Celik T., Mikhailidis D.P., Ozturk C., Demirkol S., Aparci M. The relation between atherosclerosis and the neutrophil-lymphocyte ratio. Clinical and Applied Thrombosis/Hemostasis 2015, LID-1076029615569568 [pii] (in press).
4. Bhat T., Teli S., Rijal J., Bhat H., Raza M., Khoueiry G., et al. Neutrophil to lymphocyte ratio and cardiovascular diseases: A review. Expert Review of Cardiovascular Therapy 2013, 11:55-59.
5. Boyle W.J., Simonet W.S., Lacey D.L. Osteoclast differentiation and activation. Nature 2003, 423:337-342.
6. Canpolat U., Aytemir K., Yorgun H., Sahiner L., Kaya E.B., Kabakci G., et al. Role of preablation neutrophil/lymphocyte ratio on outcomes of cryoballoon-based atrial fibrillation ablation. American Journal of Cardiology 2013, 112:513-519.
7. den Uyl D., Nurmohamed M.T., van Tuyl L.H., Raterman H.G., Lems W.F. (Sub)clinical cardiovascular disease is associated with increased bone loss and fracture risk; a systematic review of the association between cardiovascular disease and osteoporosis. Arthritis Research & Therapy 2011, 13:R5.
8. der Recke P.v., Hansen M.A., Hassager C. The association between low bone mass at the menopause and cardiovascular mortality. American Journal of Medicine 1999, 106:273-278.
9. Duffy B.K., Gurm H.S., Rajagopal V., Gupta R., Ellis S.G., Bhatt D.L. Usefulness of an elevated neutrophil to lymphocyte ratio in predicting long-term mortality after percutaneous coronary intervention. American Journal of Cardiology 2006, 97:993-996.
10. Ferrari S.L., Ahn-Luong L., Garnero P., Humphries S.E., Greenspan S.L. Two promoter polymorphisms regulating interleukin-6 gene expression are associated with circulating levels of C-reactive protein and markers of bone resorption in postmenopausal women. The Journal of Clinical Endocrinology & Metabolism 2003, 88:255-259.
11. Fici F., Celik T., Balta S., Iyisoy A., Unlu M., Demitkol S., et al. Comparative effects of nebivolol and metoprolol on red cell distribution width and neutrophil/lymphocyte ratio in patients with newly diagnosed essential hypertension. Journal of Cardiovascular Pharmacology 2013, 62:388-393.
12. Gonzalez-Fajardo J.A., Brizuela-Sanz J.A., Aguirre-Gervas B., Merino-Diaz B., Del R.L., Martin-Pedrosa M., et al. Prognostic significance of an elevated neutrophil-lymphocyte ratio in the amputation-free survival of patients with chronic critical limb ischemia. Annals of Vascular Surgery 2014, 28:999-1004.
13. Herlihy A.C., Kelly R.E., Hogan J.L., O'Connor N., Farah N., Turner M.J. Polycystic ovary syndrome and the peripheral blood white cell count. Journal of Obstetrics & Gynaecology 2011, 31:242-244.
14. Horne B.D., Anderson J.L., John J.M., Weaver A., Bair T.L., Jensen K.R., et al. Which white blood cell subtypes predict increased cardiovascular risk. Journal of the American College of Cardiology 2005, 45:1638-1643.
15. Jee S.H., Park J.Y., Kim H.S., Lee T.Y., Samet J.M. White blood cell count and risk for all-cause, cardiovascular, and cancer mortality in a cohort of Koreans. American Journal of Epidemiology 2005, 162:1062-1069.
16. Jorgensen L., Engstad T., Jacobsen B.K. Bone mineral density in acute stroke patients: Low bone mineral density may predict first stroke in women. Stroke 2001, 32:47-51.
17. Kado D.M., Browner W.S., Blackwell T., Gore R., Cummings S.R. Rate of bone loss is associated with mortality in older women: A prospective study. Journal of Bone and Mineral Research 2000, 15:1974-1980.
18. Kannel W.B., Anderson K., Wilson P.W. White blood cell count and cardiovascular disease. Insights from the Framingham Study. Journal of the American Medical Association 1992, 267:1253-1256.
19. Kim N.L., Jang H.M., Kim S.K., Ko K.D., Hwang I.C., Suh H.S. Association of arterial stiffness and osteoporosis in healthy men undergoing screening medical examination. Journal of Bone Metabolism 2014, 21:133-141.
20. Kimble R.B., Matayoshi A.B., Vannice J.L., Kung V.T., Williams C., Pacifici R. Simultaneous block of interleukin-1 and tumor necrosis factor is required to completely prevent bone loss in the early postovariectomy period. Endocrinology 1995, 136:3054-3061.
21. Koh J.M., Khang Y.H., Jung C.H., Bae S., Kim D.J., Chung Y.E., et al. Higher circulating hsCRP levels are associated with lower bone mineral density in healthy pre- and postmenopausal women: Evidence for a link between systemic inflammation and osteoporosis. Osteoporosis International 2005, 16:1263-1271.
22. Lampropoulos C.E., Papaioannou I., D'Cruz D.P. Osteoporosis-A risk factor for cardiovascular disease. Nature Reviews Rheumatology 2012, 8:587-598.
23. Laurent S., Cockcroft J., Van Bortel L., Boutouyrie P., Giannattasio C., Hayoz D., et al. Expert consensus document on arterial stiffness: Methodological issues, clinical applications. European Heart Journal 2006, 27:2588-2605.
24. Lee Y.J., Lee H.R., Shim J.Y., Moon B.S., Lee J.H., Kim J.K. Relationship between white blood cell count and nonalcoholic fatty liver disease. Digestive and Liver Disease 2010, 42:888-894.
25. Li Y., Meng S.Y., Meng C.C., Yu W.G., Wang R.T. Decreased serum bilirubin is associated with arterial stiffness in men. Nutrition, Metabolism and Cardiovascular Diseases 2013, 23:375-381.
26. Li X.S., Zhang J.R., Meng S.Y., Li Y., Wang R.T. Mean platelet volume is negatively associated with bone mineral density in postmenopausal women. Journal of Bone and Mineral Metabolism 2012, 30:660-665.
27. Li R.Y., Cao Z.G., Zhang J.R., Li Y., Wang R.T. Decreased serum bilirubin is associated with silent cerebral infarction. Arteriosclerosis, Thrombosis, and Vascular Biology 2014, 34:946-951.
28. Manolagas S.C., Jilka R.L. Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis. New England Journal of Medicine 1995, 332:305-311.
29. Marcovitz P.A., Tran H.H., Franklin B.A., O'Neill W.W., Yerkey M., Boura J., et al. Usefulness of bone mineral density to predict significant coronary artery disease. American Journal of Cardiology 2005, 96:1059-1063.
30. Nunez J., Nunez E., Bodi V., Sanchis J., Minana G., Mainar L., et al. Usefulness of the neutrophil to lymphocyte ratio in predicting long-term mortality in ST segment elevation myocardial infarction. American Journal of Cardiology 2008, 101:747-752.
31. Riggs B.L. The mechanisms of estrogen regulation of bone resorption. Journal of Clinical Investigation 2000, 106:1203-1204.
32. Ruggiero C., Metter E.J., Cherubini A., Maggio M., Sen R., Najjar S.S., et al. White blood cell count and mortality in the Baltimore Longitudinal Study of Aging. Journal of the American College of Cardiology 2007, 49:1841-1850.
33. Satoh H., Kishi R., Tsutsui H. Metabolic syndrome is a significant and independent risk factor for increased arterial stiffness in Japanese subjects. Hypertension Research 2009, 32:1067-1071.
34. Scheidt-Nave C., Bismar H., Leidig-Bruckner G., Woitge H., Seibel M.J., Ziegler R., et al. Serum interleukin 6 is a major predictor of bone loss in women specific to the first decade past menopause. The Journal of Clinical Endocrinology & Metabolism 2001, 86:2032-2042.
35. Shaffer J.R., Kammerer C.M., Rainwater D.L., O'Leary D.H., Bruder J.M., Bauer R.L., et al. Decreased bone mineral density is correlated with increased subclinical atherosclerosis in older, but not younger, Mexican American women and men: The San Antonio Family Osteoporosis Study. Calcified Tissue International 2007, 81:430-441.
36. Sumino H., Ichikawa S., Kasama S., Takahashi T., Kumakura H., Takayama Y., et al. Elevated arterial stiffness in postmenopausal women with osteoporosis. Maturitas 2006, 55:212-218.
37. Teng Z.Y., Pei L.C., Zhang Y., Li Y., Wang R.T. Whole blood viscosity is negatively associated with bone mineral density in postmenopausal women with osteoporosis. Bone 2013, 56:343-346.
38. Tomiyama H., Tanaka H., Hashimoto H., Matsumoto C., Odaira M., Yamada J., et al. Arterial stiffness and declines in individuals with normal renal function/early chronic kidney disease. Atherosclerosis 2010, 212:345-350.
39. Turin T.C., Kita Y., Rumana N., Takashima N., Kadota A., Matsui K., et al. Brachial-ankle pulse wave velocity predicts all-cause mortality in the general population: Findings from the Takashima study, Japan. Hypertension Research 2010, 33:922-925.
40. van der Klift M., Pols H.A., Hak A.E., Witteman J.C., Hofman A., de Laet C.E. Bone mineral density and the risk of peripheral arterial disease: The Rotterdam Study. Calcified Tissue International 2002, 70:443-449.
41. Woodard G.A., Mehta V.G., Mackey R.H., Tepper P., Kelsey S.F., Newman A.B., et al. C-reactive protein is associated with aortic stiffness in a cohort of African American and white women transitioning through menopause. Menopause 2011, 18:1291-1297.
42. Xu L., Jiang C.Q., Lam T.H., Yue X.J., Cheng K.K., Liu B., et al. Brachial-ankle pulse wave velocity and cardiovascular risk factors in the non-diabetic and newly diagnosed diabetic Chinese: Guangzhou Biobank Cohort Study-CVD. Diabetes/Metabolism Research and Reviews 2010, 26:133-139.
43. Yamashina A., Tomiyama H., Takeda K., Tsuda H., Arai T., Hirose K., et al. Validity, reproducibility, and clinical significance of noninvasive brachial-ankle pulse wave velocity measurement. Hypertension Research 2002, 25:359-364.
44. Zaydun G., Tomiyama H., Hashimoto H., Arai T., Koji Y., Yambe M., et al. Menopause is an independent factor augmenting the age-related increase in arterial stiffness in the early postmenopausal phase. Atherosclerosis 2006, 184:137-142.