Instant coffee extract with high chlorogenic acids content inhibits hepatic G-6-Pase in vitro, but does not reduce the glycaemia

Cell Biochemistry and Function

Volumn 33, Issue 4, 2015, Pages 183-187

  Bassoli, Bruna Kempfer ^a   Cassolla, Priscila ^a   Borba Murad, Glaucia Regina ^a   Constantin, Jorgete ^b   Salgueiro Pagadigorria, Clairce Luzia ^b   Bazotte, Roberto Barbosa ^b   de Souza, Helenir Medri ^a  

^a STATE UNIVERSITY OF LONDRINA   (Brazil)

^b STATE UNIVERSITY OF MARINGÁ   (Brazil)

Author keywords

Chlorogenic acid; Glucose 6 phosphatase; Glycaemia; Instant coffee extract; Liver glucose output; Liver perfusion

Indexed keywords

CHLOROGENIC ACID; GLUCOSE; GLUCOSE 6 PHOSPHATASE; CAFFEOYLQUINIC ACID; COFFEE; ENZYME INHIBITOR; GLUCOSE BLOOD LEVEL; PLANT EXTRACT; QUINIC ACID;

ANIMAL EXPERIMENT; ARTICLE; COFFEE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME INHIBITION; GLUCOSE BLOOD LEVEL; GLYCOGENOLYSIS; IN VITRO STUDY; LIVER MICROSOME; LIVER PERFUSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; GLYCEMIC INDEX; HUMAN; LIVER; METABOLISM; WISTAR RAT;

RATTUS;

ANIMALS; BLOOD GLUCOSE; CHLOROGENIC ACID; COFFEE; ENZYME INHIBITORS; GLUCOSE-6-PHOSPHATASE; GLYCEMIC INDEX; HUMANS; LIVER; MALE; MICROSOMES, LIVER; PLANT EXTRACTS; QUINIC ACID; RATS; RATS, WISTAR;

EID: 84931572766     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.3099     Document Type: Article

References (36)

1. Clifford MN. Chlorogenic acids and other cinnamates-nature, occurrence and dietary burden. J Sci Food Agric 1999; 79: 362-372.
2. Monteiro MC, Trugo LC. Determination of bioactive compounds in Brazilian roasted coffees. Química Nova 2005; 28(4): 637-641.
3. Nogueira M, Trugo LC. Chlorogenic acid isomers, caffeine and trigonellin contents in Brazilian instant coffee. Cienc Tecnol Alimen 2003; 23(2): 296-299.
4. Meng S, Cao J, Feng Q, Peng J, Hu Y. Roles of chlorogenic acid on regulating glucose and lipids metabolism: a review. Evid Based Complement Alternat Med 2013; 2013: 801457. doi: 10.1155/2013/801457
5. Stefanello N, Schmatz R, Pereira LB, et al. Effects of chlorogenic acid, caffeine, and coffee on behavioral and biochemical parameters of diabetic rats. Mol Cell Biochem 2014; 388(1-2): 277-286.
6. Arion WJ, Canfield WK, Ramos FC, et al. Clorogenic acid and hydroxynitribenzaldehyde: new inhibitors of hepatic glucose-6-phosphatase. Arch Biochem Biophys 1997; 339(2): 315-322.
7. Hemmerle H, Burger H-J, Below P, et al. Clorogenic acid and sintetic clorogenic acid derivatives: novel inhibitors of hepatic glucose-6-fosfatase translocase. J Med Chem 1997; 40(2): 137-145.
8. Herling AW, Burger H-J, Schwab D, Hemmerle H, Below P, Schubert G. Pharmacodynamic profile of a novel inhibitor of the glucose-6-phosphatase system. Am J Physiol 1998; 278(37): G1087-1093.
9. Parker JC, Vanvolkenburg MA, Levy CB, et al. Plasma glucose levels are reduced in rats and mice treated with an inhibitor of glucose-6-phosphate translocase. Diabetes 1998; 47: 1630-1636.
10. Burger H-J, Hemmerle H, Schubert G, et al. Inhibition of glucose-6-phosphatase affects glucose output and glycogenesis in rat hepatocytes. Diabetologia 1994; 37(1): A135.
11. De Fronzo RA, Ferrannin E, Simonson DC. Fasting hyperglycemia in non-insulin-dependent diabetes mellitus: contributions of excessive hepatic glucose production and impaired tissue glucose uptake. Metab 1989; 38: 387-395.
12. Liu Z, Barre EJ, Dalken AC, Zwart AD, Chou JY. Effect of acute diabetes on rat hepatic glucose-6-phophatase activity and its messenger RNA level. Biochem Biophys Res Commun 1994; 205: 680-686.
13. Tunnicliffe JM, Shearer J. Coffee, glucose homeostasis, and insulin resistance: physiological mechanisms and mediators. Appl Physiol Nutr Metab 2008; 33(6): 1290-1300.
14. Akash MS, Rehman K, Chen S. Effects of coffee on type 2 diabetes mellitus. Nutrition 2014; 30(7-8): 755-763.
15. Würzner H-P, Lindström E, Vuataz L. A 2-year feeding study of instant coffees in rats. I-body weight, food consumption, haematological parameters and plasma chemistry. Food Cosmet Toxicol 1977; 15: 7-16.
16. Bicchi CP, Binello AE, Pellegrino GM, Van AC. Characterization of green and roasted coffees through the chlorogenic acid fraction by HPLC-UV and principal component analysis. J Agric Food Chem 1995; 43(6): 1549-1555.
17. Instituto Adolfo Lutz. Normas Analíticas do Instituto Adolfo Lutz (3nd edn). Instituto Adolfo Lutz: São Paulo, 1985.
18. Bygrave FL. Properties of energy-dependent calcium transport by rat liver microsomal fractions as revealed by initial-rate measurements. Biochem J 1978; 170: 87-91.
19. Fiske CH, Subarrow Y. The colorimetric determination of phosphorus. J Biol Chem 1925; 66: 375-400.
20. Lowry OH, Rosebrough NJ, Farr AL, Randall RJJ. Protein measurement with Folin phenol reagent. J Biol Chem 1982; 193: 131-138.
21. Barrena HC, Gazola VAFG, Furlan MMDP, Garcia RF, Souza HM, Bazotte RB. Ketogenesis evaluation in perfused liver of diabetic rats submitted to short-term insulin-induced hypoglycemia. Cell Biochem Funct 2009; 27: 383-387.
22. Dubowski KM. An o-toluidine method for body-fluid glucose determination. Clin Chem 1962; 8: 215-225.
23. Czok R, Lamprech W. Pyruvate, phosphoenolpyruvate and D-glycerate-2-phosphate. In Methods of Enzymatic Analysis. Bergmeyer HU (ed.). Academic Press: New York, 1974; 1446-1448.
24. Gutmann I, Wahlefeld W. L-(+)-Lactate. Determination with lactate dehydrogenase and NAD. In Methods of Enzymatic Analysis. Bergmeyer HU (ed.). Academic Press: New York, 1974; 1464-1472.
25. Ky C-L, Noirot M, Hamon S. Comparison of five purification methods for chlorogenic acids in green coffee beans (Coffea sp). J Agric Food Chem 1997; 45(3): 786-790.
26. Akash MS, Shen Q, Rehman K, Chen S. Interleukin-1 receptor antagonist: a new therapy for type 2 diabetes mellitus. J Pharm Sci 2012; 101(5): 1647-1658.
27. Akash MS, Rehman K, Chen S. Role of inflammatory mechanisms in pathogenesis of type 2 diabetes mellitus. J Cell Biochem 2013; 114(3): 525-531.
28. Bailey CJ. Potencial new treatments for type 2 diabetes. Trends Pharmacol Sci 2000; 21: 259-265.
29. Akash MS, Rehman K, Chen S. An overview of valuable scientific models for diabetes mellitus. Curr Diabetes Rev 2013; 9(4): 286-293.
30. Ishii EL, Bracht A. Glucose release by the liver under conditions of reduced activity of glucose 6-phosphatase. J Med Biol Res 1987; 20: 837-843.
31. Schwab D, Herling AW, Hemmerle H, Schubert G, Hagenbuch B, Burger H-J. Hepatic uptake of synthetic chlorogenic acid derivatives by the organic anion transport proteins. J Pharmacol Exp Ther 2001; 296(1): 91-98.
32. st International Conference on Coffee Science, Montpellier-France. CD-ROM ASIC Montpellier 2006; PC401.
33. Andrade-Cetto A, Wiedenfeld H. Hypoglycemic effect of Cecropia obtusifolia on streptozotocin diabetic rats. J Ethnopharmacol 2001; 78: 145-149.
34. Tunnicliffe JM, Eller LK, Reimer RA, Hittel DS, Shearer J. Chlorogenic acid differentially affects postprandial glucose and glucose-dependent insulinotropic polypeptide response in rats. Appl Physiol Nutr Metab 2011; 36(5): 650-659.
35. +-dependent D-glucose uptake in rat intestinal brush border membrane vesicles. J Nutr 1989; 119(11): 1698-1704.
36. Bassoli BK, Cassolla P, Borba-Murad GR, et al. Chlorogenic acid reduces the plasma glucose peak in the oral glucose tolerance test: effects on hepatic glucose release and glycaemia. Cell Biochem Funct 2008; 26: 320-328.