A novel subpopulation of peripheral blood mononuclear cells presents in major burn patients

Burns

Volumn 41, Issue 5, 2015, Pages 998-1007

  Liu, Hongbin ^a   Ding, Jie ^a   Ma, Zengshuan ^a,b   Zhu, Zhenshen ^a,b   Shankowsky, Heather A ^a   Tredget, Edward E ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Burn injury; Fibrocytes; Hypertrophic scars; Macrophages

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CONNECTIVE TISSUE GROWTH FACTOR; GROWTH FACTOR; LEUKOCYTE SPECIFIC PROTEIN 1; PROCOLLAGEN; STROMAL CELL DERIVED FACTOR 1; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; CXCR4 PROTEIN, HUMAN; DCN PROTEIN, HUMAN; DECORIN; LSP1 PROTEIN, HUMAN; MSR1 PROTEIN, HUMAN; SCAVENGER RECEPTOR A; SCLEROPROTEIN; TLR4 PROTEIN, HUMAN;

ADULT; ARTICLE; BLOOD SAMPLING; BODY SURFACE; BURN; BURN PATIENT; CELL DIFFERENTIATION; CELL MIGRATION; CELL SUBPOPULATION; CHEMOTAXIS; CLINICAL ARTICLE; CONNECTIVE TISSUE CELL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYPERTROPHIC SCAR; IN VITRO STUDY; INJURY SEVERITY; MACROPHAGE; MALE; MIDDLE AGED; MYOFIBROBLAST; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; SCAR FORMATION; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; THERMAL INJURY; YOUNG ADULT; BLOOD; CELL CULTURE; CELL MIGRATION ASSAY; CYTOLOGY; DOWN REGULATION; FIBROBLAST; INJURY SCALE; METABOLISM; MONONUCLEAR CELL; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN;

ADULT; BODY SURFACE AREA; BURNS; CELL DIFFERENTIATION; CELL MIGRATION ASSAYS; CELLS, CULTURED; CHEMOTAXIS; CICATRIX, HYPERTROPHIC; CONNECTIVE TISSUE CELLS; DECORIN; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX PROTEINS; FEMALE; FIBROBLASTS; HUMANS; IN VITRO TECHNIQUES; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MALE; MICROFILAMENT PROTEINS; MIDDLE AGED; MYOFIBROBLASTS; PROCOLLAGEN; RECEPTORS, CXCR4; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SCAVENGER RECEPTORS, CLASS A; SIGNAL TRANSDUCTION; SKIN; TOLL-LIKE RECEPTOR 4; TRAUMA SEVERITY INDICES; YOUNG ADULT;

EID: 84931571602     PISSN: 03054179     EISSN: 18791409     Source Type: Journal    
DOI: 10.1016/j.burns.2014.12.005     Document Type: Article

References (44)

1. R. Rudolph Wide-spread scars, hypertrophic scars, and keloids Clin Plast Surg 14 1987 253 260
2. A. Ladak, and E.E. Tredget Pathophysiology and Management of the Burn Scar Clin Plastic Surg 36 2009 661 674
3. L. Yang, P.G. Scott, C. Dodd, A. Medina, H. Jiao, and H.A. Shankowsky Identification of fibrocytes in postburn hypertrophic scar Wound Repair Regen 13 2005 398 404
4. M.D. Armando Gabrielli, V. Enrico, M.D. Avvedimento, and M.D. Thomas Krieg Mechanisms of Disease Scleroderma N Engl J Med 360 2009 1989 2003
5. L. Mori, A. Bellini, M.A. Stacey, M. Schmidt, and S. Mattoli Fibrocytes contribute to the myofibroblast population in wounded skin and originate from the bone marrow Exp Cell Res 304 1 2005 81 90
6. R. Abe, S.C. Donnelly, T. Peng, R. Bucala, and C.N. Metz Peripheral blood fibrocytes: differentiation pathway and migration to wound sites Immunology 166 12 2001 7556 7562
7. M. Schmidt, G. Sun, M.A. Stacey, L. Mori, and S. Mattoli Identification of circulating fibrocytes as precursors of bronchial myofibroblasts in asthma J Immunol 171 1 2003 380 389
8. L. Yang, P.G. Scott, C. Dodd, A. Medina, H. Jiao, and H.A. Shankowsky Identification of fibrocytes in postburn hypertrophic scar Wound Repair Regen 13 4 2005 398 404
9. G. Song, D.T. Nguyen, G. Pietramaggiori, S. Scherer, B. Chen, and Q. Zhan Use of the parabiotic model in studies of cutaneous wound healing to define the participation of circulating cells Wound Repair Regen 18 4 2010 426 432
10. I.I. Metchnikov Immunity of infectious diseases 1901 Masson Paris, France
11. A.A. Maximow Cultures of blood leucocytes: from lymphocyte and monocyte to connective tissue Arch Exp Zellforsch 5 1928 169 268
12. R. Bucala, L.A. Spiegel, J. Chesney, M. Hogan, and A. Cerami Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair Mol Med 1 1994 71 81
13. R.M. Strieter, E.C. Keeley, M.A. Hughes, M.D. Burdick, and B. Mehrad The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of pulmonary fibrosis J Leukoc Biol 86 2009 1111 1118
14. K. Tashiro, H. Tada, R. Heiker, M. Shirozu, T. Nakano, and T. Honjo Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins Science 261 1993 600 603
15. C.C. Bleul, R.C. Fuhlbrigge, J.M. Casasnovas, A. Aiuti, and T.A. Springer A highly efficacious lymphocyte chemoattractant, stromal cell derived factor 1 (SDF-1) J Exp Med 184 1996 1101 1109
16. T. Hamada, R. Möhle, J. Hesselgesser, J. Hoxie, R.L. Nachman, M.A. Moore, and S. Rafii Transendothelial migration of megakaryocytes in response to stromal cell-derived factor 1 (SDF-1) enhances platelet formation J Exp Med 188 1998 539 548
17. L.J. Yang, P.G. Scott, J. Giuffre, H.A. Shankowsky, A. Ghahary, and E.E. Tredget Peripheral blood fibrocytes from burn patients: identification and quantification of fibrocytes in adherent cells cultured from peripheral blood mononuclear cells Lab Investig 82 2002 1183 1192
18. J.F. Wang, H.Y. Jiao, T.L. Stewart, H.A. Shankowsky, P.G. Scott, and E.E. Tredget Fibrocytes from burn patients regulate the activities of fibroblasts Wound Repair Regen 15 2007 113 121
19. H.K. Kao, B. Chen, G.F. Murphy, Q. Li, D.P. Orgill, and L. Guo Peripheral blood fibrocytes: enhancement of wound healing by cell proliferation, re-epithelialization, contraction, and angiogenesis Ann Surg 254 2011 1066 1074
20. M.G. Schwacha Macrophages and post-burn immune dysfunction Burns 29 2003 1 14
21. J.F. Wang, K. Hori, J. Ding, Y. Huang, P. Kwan, and A. Ladak Toll-like receptors expressed by dermal fibroblasts contribute to hypertrophic scarring J Cell Physiol 226 2011 1265 1273
22. G.E. Spyrou, D.A. Watt, and I.L. Naylor The origin and mode of fibroblast migration and proliferation in granulation tissue Br J Plast Surg 51 6 1998 455 461
23. V. Sarrazy, F. Billet, L. Micallef, B. Coulomb, and A. Desmoulliere Mechanisms of pathological scarring: role of myofibroblasts and current developments Wound Repair Regen 19 S1 2011 S10 S15
24. T. Nagamoto, G. Eguchi, and D.C. Beebe Alpha-smooth muscle actin expression in cultured lens epithelial cells Investig Ophthalmol Vis Sci 41 5 2000 1122 1129
25. J.F. Wang, H.Y. Jiao, T.L. Stewart, H.A. Shankowsky, P.G. Scott, and E.E. Tredget Improvement in postburn hypertrophic scar after treatment with IFN-alpha2b is associated with decreased fibrocytes J Interferon Cytokine Res 27 2007 921 930
26. D. Pilling, T. Fan, D. Huang, B. Kaul, and R.H. Gomer Identification of markers that distinguish monocyte-derived fibrocytes from monocytes, macrophages, and fibroblasts PLoS One 4 2009 7475 7477
27. Babak Mahdavian Delavary, Willem M. van der Veer, Marjolein van Egmond, Frank B. Niessen, and Robert H.J. Beelen Macrophages in skin injury and repair Immunobiology 216 7 2011 753 762
28. G. Grieb, G. Steffens, N. Pallua, J. Bernhagen, and R. Bucala Circulating fibrocytes - biology and mechanisms in wound healing and scar formation Int Rev Cell Mol Biol 291 2011 1 19
29. Y. Wu, J. Wang, P.G. Scott, and E.E. Tredget Bone marrow-derived stem cells in wound healing: a review Wound Repair Regen 1 2007 S18 S26
30. C.L. Baum, and C.J. Arpey Normal cutaneous wound healing: clinical correlation with cellular and molecular events Dermatol Surg 31 2005 674 686
31. J. Ding, K. Hori, R. Zhang, Y. Marcoux, D. Honardoust, and H.A. Shankowsky Stromal cell-derived factor 1 (SDF-1) and its receptor CXCR4 in the formation of postburn hypertrophic scar (HTS) Wound Repair Regen 19 2011 568 578
32. K.P. Mollen, R.J. Anand, A. Tsung, J.M. Prince, R.M. Levy, and T.R. Billiar Emerging paradigm: toll like receptor 4-sentinel for the detection of tissue damage Shock 26 2006 430 437
33. + regulatory T cells control innate immune reactivity after injury J Immunol 174 2005 2957 2963
34. C.Y. Ling, M. Yamashita, J.X. Zhang, D.M. Bless, and N.V. Welham Reactive response of fibrocytes to vocal fold mucosal injury in rat Wound Repair Regen 18 2010 514 523
35. S. Mattoli, A. Bellini, and M. Schmidt The role of a human hematopoietic mesenchymal progenitor in wound healing and fibrotic diseases and implications for therapy Curr Stem Cell Res Therapy 4 2009 266 280
36. S. Avniel, Z. Arik, A. Maly, A. Sagie, H.B. Basst, and M.D. Yahana Involvement of the CXCL12/CXCR4 pathway in the recovery of skin following burns J Investig Dermatol 126 2006 468 476
37. M. Triantafilou, P.M. Lepper, C.D. Briault, M.A. Ahmed, J.M. Dmochowski, and C. Schumann Chemokine receptor 4 (CXCR4) is part of the lipopolysaccharide "sensing apparatus" Eur J Immunol 38 2008 192 203
38. M. Triantafilou, and K. Triantafilou Receptor cluster formation during activation by bacterial products J Endotoxin Res 9 2003 331 335
39. B.M. Delavary, W.M. van der Veer, M. van Egmond, F.B. Nissen, and R.H. Beelen Macrophages in skin injury and repair Immunobiology 216 2011 753 762
40. M. Alexander, I.H. Chaudry, and M.G. Schwacha Relationships between burn size, immunosuppression and macrophage hyperactivity in a murine model of thermal injury Cell Immunol 220 2002 63 69
41. E.E. Tredget, L. Yang, M. Delehanty, H. Shankowsky, and P.G. Scott Polarized Th2 cytokine production in patients with hypertrophic scar following thermal injury J Interferon Cytokine Res 26 3 2006 179 189
42. A. Armour, P.G. Scott, and E.E. Tredget Cellular and molecular pathology of HTS: basis for treatment Wound Repair Regen 15 2007 S6 S17
43. S.K. Mathai, M. Gulati, X.Y. Peng, T.R. Russell, A.C. Shaw, and A.N. Rubinowitz Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype Lab Investig 90 2010 812 823
44. T.E. Quan, S. Cowper, S.P. Wu, L.K. Bockenstedt, and R. Bucala Circulating fibrocytes: collagen-secreting cells of the peripheral blood Int J Biochem Cell Biol 36 2004 598 606