Malnutrition and cachexia in patients with head and neck cancer treated with (chemo)radiotherapy

Reports of Practical Oncology and Radiotherapy

Volumn 20, Issue 4, 2015, Pages 249-258

  Gorenc, Mojca ^a   Kozjek, Nada Rotovnik ^a   Strojan, Primož ^a  

^a INSTITUTE OF ONCOLOGY   (Slovenia)

Author keywords

Cachexia; Head and neck cancer; Malnutrition; Radiotherapy; Weight loss

Indexed keywords

ACETYLCYSTEINE; ANTIANDROGEN; ANTINEOPLASTIC AGENT; CARNITINE; CELECOXIB; ENOBOSARM; MEGESTROL ACETATE; THALIDOMIDE; THIOCTIC ACID;

ANOREXIA; BODY MASS; CACHEXIA; CHEMORADIOTHERAPY; DIET THERAPY; ENTERIC FEEDING; FEEDING; FOLLOW UP; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HORMONAL THERAPY; HUMAN; MALNUTRITION; NASOGASTRIC TUBE; NUTRITIONAL ASSESSMENT; NUTRITIONAL STATUS; PARENTERAL NUTRITION; PATHOGENESIS; PERCUTANEOUS ENDOSCOPIC GASTROSTOMY; QUALITY OF LIFE; REVIEW;

EID: 84931568450     PISSN: 15071367     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rpor.2015.03.001     Document Type: Review

References (83)

1. Sanderson R.J., Ironside J.A.D. Squamous cell carcinomas of the head and neck. BMJ 2002, 325:822-827.
2. Ferlay J., Shin H.R., Bray F., Forman D., Mathers C., Parkin D.M. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010, 127:2893-2917.
3. Langius J.A.E., Doornaert P., Spreeuwenberg M.D., Langendijk J.A., Leemans C.R., Schueren M.A. Radiotherapy on the neck nodes predicts severe weight loss in patients with early stage laryngeal cancer. Radiother Oncol 2010, 97:80-85.
4. Unsal D., Mentes B., Akmansu M., Uner A., Oguz M., Pak Y. Evaluation of nutritional status in cancer patients receiving radiotherapy: a prospective study. Am J Clin Oncol 2006, 29:183-188.
5. Ravasco P., Monteiro-Grillo I., Vidal P.M., Camilo M.E. Nutritional deterioration in cancer: the role of disease and diet. Clin Oncol (R Coll Radiol) 2003, 15:443-450.
6. Toomey D., Redmond H.P., Bouchier-Hayes D. Mechanisms mediating cancer cachexia. Cancer 1995, 76:2418-2426.
7. Lucia S., Esposito M., Rossi Fanelli F., Muscaritoli M. Cancer cachexia: from molecular mechanisms to patient's care. Crit Rev Oncog 2012, 17:315-321.
8. Lee H., Havrila C., Bravo V., et al. Effect of oral nutritional supplementation on weight loss and percutaneous endoscopic gastrostomy tube rates in patients treated with radiotherapy for oropharyngeal carcinoma. Support Care Cancer 2008, 16:285-289.
9. Larsson M., Hedelin B., Johansson I., Athlin E. Eating problems and weight loss for patients with head and neck cancer. Cancer Nurs 2005, 28:425-435.
10. Zadák Z., Tichá A., Hyšpler R. Disease specific substrates in cancer cachexia - reality and anticipation. Rep Pract Oncol Radiother 2013, 18:34-43.
11. Gugić J., Strojan P. Squamous cell carcinoma of the head and neck in the elderly. Rep Pract Oncol Radiother 2013, 18:16-25.
12. Van Bokhorst D.S., van Leeuwen P.A., Kuik D.J., et al. The impact of nutritional status on the prognoses of patients with advanced head and neck cancer. Cancer 1999, 86:519-527.
13. Beaver M.E., Matheny K.E., Roberts D.B., Myers J.N. Predictors of weight loss during radiation therapy. Otolaryngol Head Neck Surg 2001, 125:645-648.
14. van den Berg M.G., Rasmussen-Conrad E.L., van Nispen L., van Binsbergen J.J., Merkx M.A. A prospective study on malnutrition and quality of life in patients with head and neck cancer. Oral Oncol 2008, 44:830-837.
15. Capuano G., Grosso A., Gentile P.C., et al. Influence of weight loss on outcomes in patients with head and neck cancer undergoing concomitant chemoradiotherapy. Head Neck 2008, 30:503-508.
16. Jager-Wittenaar H., Dijkstra P.U., Vissink A., van der Laan B.F., van Oort R.P., Roodenburg J.L. Malnutrition and quality of life in patients treated for oral or oropharyngeal cancer. Head Neck 2011, 33:490-496.
17. Chang P.H., Yeh K.Y., Huang J.S., et al. Pretreatment performance status and nutrition are associated with early mortality of locally advanced head and neck cancer patients undergoing concurrent chemoradiation. Eur Arch Otorhinolaryngol 2013, 270:1909-1915.
18. Meyer F., Fortin A., Wang C.S., Liu G., Bairati I. Predictors of severe acute and late toxicities in patients with localized head-and-neck cancer treated with radiation therapy. Int J Radiat Oncol Biol Phys 2012, 82:1454-1462.
19. Agarwal E., Ferguson M., Banks M., et al. Malnutrition and poor food intake are associated with prolonged hospital stay, frequent readmissions, and greater in-hospital mortality: results from the Nutrition Care Day Survey 2010. Clin Nutr 2013, 32:737-745.
20. McRackan T.R., Watkins J.M., Herrin A.E., et al. Effect of body mass index on chemoradiation outcomes in head and neck cancer. Laryngoscope 2008, 118:1180-1185.
21. Meier R., Stratton R.J. Basics in clinical nutrition 2004, Galen, Sobotka. 3rd ed.
22. Muscaritoli M., Anker S.D., Argiles J., et al. Consensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by Special Interest Groups (SIG) "cachexia-anorexia in chronic wasting diseases" and "nutrition in geriatrics". Clin Nutr 2010, 29:154-159.
23. Fearon K., Strasser F., Anker S.D., et al. Definition and classification of cancer cachexia: an international consensus. Lancet Oncol 2011, 12:489-495.
24. Tisdale M.J. Mechanisms of cancer cachexia. Physiol Rev 2009, 89:381-410.
25. Tisdale M.J. Cancer cachexia. Curr Opin Gastroenterol 2010, 26:146-151.
26. Couch M.E., Dittus K., Toth M.J., et al. Cancer cachexia update in head and neck cancer: pathophysiology and treatment. Head Neck 2014, [Epub ahead of print].
27. Nicolini A., Ferrari P., Masoni M.C., et al. Malnutrition, anorexia and cachexia in cancer patients: a mini-review on pathogenesis and treatment. Biomed Pharmacother 2013, 67:807-817.
28. Lønbro S., Dalgas U., Primdahl H., et al. Progressive resistance training rebuilds lean body mass in head and neck cancer patients after radiotherapy-results from the randomized DAHANCA 25B trial. Radiother Oncol 2013, 108:314-319.
29. Lønbro S., Dalgas U., Primdahl H., Overgaard J., Overgaard K. Feasibility and efficacy of progressive resistance training and dietary supplements in radiotherapy treated head and neck cancer patients - the DAHANCA 25A study. Acta Oncol 2013, 52:310-318.
30. Abe Vicente M., Barão K., Silva T.D., Forones N.M. What are the most effective methods for assessment of nutritional status in outpatients with gastric and colorectal cancer?. Nutr Hosp 2013, 28:585-591.
31. Prevost V., Joubert C., Heutte N., Babin E. Assessment of nutritional status and quality of life in patients treated for head and neck cancer. Eur Ann Otorhinolaryngol Head Neck Dis 2014, 131:113-120.
32. Alshadwi A., Nadershah M., Carlson E.R., Young L.S., Burke P.A., Daley B.J. Nutritional considerations for head and neck cancer patients: a review of the literature. J Oral Maxillofac Surg 2013, 71:1853-1860.
33. Bauer J., Capra S., Ferguson M. Use of the scored Patient-Generated Subjective Global Assessment (PG-SGA) as a nutrition assessment tool in patients with cancer. Eur J Clin Nutr 2002, 56:779-785.
34. Isenring E., Bauer J., Capra S. The scored Patient-generated Subjective Global Assessment (PG-SGA) and its association with quality of life in ambulatory patients receiving radiotherapy. Eur J Clin Nutr 2003, 57:305-309.
35. Elia M. The 'MUST' report. Nutritional screening of adults: a multidisciplinary responsibility. Malnutrition Advisory Group (MAG) 2003, BAPEN, Redditch.
36. Kondrup J., Allison S.P., Vellas B., Plauth M. ESPEN Guidelines for nutritional screening. Clin Nutr 2003, 22:415-421.
37. Kondrup J., Rasmussen H., Hamberg O., Stanga Z. Nutritional Risk screening (NRS 2002): a new method based on analysis of controlled clinical trials. Clin Nutr 2003, 22:321-336.
38. Neelemaat F., Meijers J., Kruizenga H., van Ballegooijen H., van Bokhorstde van der Schueren M. Comparison of five malnutrition screening tools in one hospital inpatient sample. J Clin Nurs 2011, 20:2095-2382.
39. Takenaka Y., Takemoto N., Nakahara S., et al. Prognostic significance of body mass index before treatment of head and neck cancer. Head Neck 2014, [Epub ahead of print].
40. Schwenk A., Beisenherz A., Römer K., Kremer G., Salzberger B., Elia M. Phase angle from bioelectrical impedance analysis remains an independent predictive marker in HIV-infected patients in the era of highly active antiretroviral treatment. Am J Clin Nutr 2000, 72:496-501.
41. Paiva S.I., Borges L.R., Halpern-Silveira D., Assunção M.C., Barros A.J., Gonzalez M.C. Standardized phase angle from bioelectrical impedance analysis as prognostic factor for survival in patients with cancer. Support Care Cancer 2010, 19:187-192.
42. Unal D., Orhan O., Eroglu C., Kaplan B. Prealbumin is a more sensitive marker than albumin to assess the nutritional status in patients undergoing radiotherapy for head and neck cancer. Contemp Oncol 2013, 17:276-280.
43. Salas S., Deville J.L., Giorgi R., et al. Nutritional factors as predictors of response to radio-chemotherapy and survival in unresectable squamous head and neck carcinoma. Radiother Oncol 2008, 87:195-200.
44. Lees J. Incidence of weight loss in head and neck cancer patients on commencing radiotherapy treatment at a regional oncology centre. Eur J Cancer Care 1999, 8:133-136.
45. Johnston C.A., Keane T.J., Prudo S.M. Weight loss in patients receiving radical radiation therapy for head and neck cancer: a prospective study. JPEN J Parenter Enteral Nutr 1982, 6:399-402.
46. Langius J.A., Bakker S., Rietveld D.H., et al. Critical weight loss is a major prognostic indicator for disease-specific survival in patients with head and neck cancer receiving radiotherapy. Br J Cancer 2013, 109:1093-1099.
47. Paleri V., Roe J.W., Strojan P., et al. Strategies to reduce long-term postchemoradiation dysphagia in patients with head and neck cancer: an evidence-based review. Head Neck 2014, 36:431-443.
48. Gomez-Millan J., Fernandez R.J., Medina Carmona J.A. Current status of IMRT in head and neck cancer. Rep Pract Oncol Radiother 2013, 18:371-375.
49. Alterio D., Ciardo D., Preda L., et al. Contouring of the pharyngeal superior constrictor muscle (PSCM). A cooperative study of the Italian Association of Radiation Oncology (AIRO) Head and Neck Group. Radiother Oncol 2014, 112:337-342.
50. Al-Mamgani A., van Rooij P., Verduijn G.M., Mehilal R., Kerrebijn J.D., Levendag P.C. The impact of treatment modality and radiation technique on outcomes and toxicity of patients with locally advanced oropharyngeal cancer. Laryngoscope 2013, 123:386-393.
51. Chen A.Y., Frankowski R., Bishop-Leone J., et al. The development and validation of a dysphagia-specific quality-of-life questionnaire for patients with head and neck cancer: the M. D. Anderson dysphagia inventory. Arch Otolaryngol Head Neck Surg 2001, 127:870-876.
52. Langius J.A., Zandbergen M.C., Eerenstein S.E., et al. Effect of nutritional interventions on nutritional status, quality of life and mortality in patients with head and neck cancer receiving (chemo)radiotherapy: a systematic review. Clin Nutr 2013, 32:671-678.
53. Ravasco P., Monteiro-Grillo I., Marques Vidal P., Camilo M.E. Impact of nutrition on outcome: a prospective randomized controlled trial in patients with head and neck cancer undergoing radiotherapy. Head Neck 2005, 27:659-668.
54. Arends J., Bodoky G., Bozzetti F., et al. ESPEN guidelines on enteral nutrition: non-surgical oncology. Clin Nutr 2006, 25:295-310.
55. Goodwin W.J., Byers P.M. Nutritional management of the head and neck cancer patient. Med Clin North Am 1993, 77:597-610.
56. Lopez M.J., Robinson P., Madden T., Highbarger T. Nutritional support and prognosis in patients with head and neck cancer. J Surg Oncol 1994, 55:33-36.
57. Whale Z., Lyne P.A., Papanikolaou P. Pain experience following radical treatment for head and neck cancer. Eur J Oncol Nurs 2001, 5:112-120.
58. Campbell B.H., Marbella A., Layde P.M. Quality of life and recurrence concern in survivors of head and neck cancer. Laryngoscope 2000, 110:895-906.
59. Bosaeus I. Nutritional support in multimodal therapy for cancer cachexia. Support Care Cancer 2008, 16:447-451.
60. Akbulut G. New perspective for nutritional support of cancer patients: enteral/parenteral nutrition. Exp Ther Med 2011, 2:675-684.
61. Hearne B.E., Dunaj J.M., Daly J.M., et al. Enteral nutrition support in head and neck cancer: tube vs. oral feeding during radiation therapy. J Am Diet Assoc 1985, 85:669-674.
62. Daly J.M., Hearne B., Dunaj J., et al. Nutritional rehabilitation in patients with advanced head and neck cancer receiving radiation therapy. Am J Surg 1984, 148:514-520.
63. Silander E., Nyman J., Bove M., Johansson L., Larsson S., Hammerlid E. Impact of prophylactic percutaneous endoscopic gastrostomy on malnutrition and quality of life in patients with head and neck cancer: a randomized study. Head Neck 2012, 34:1-9.
64. Corry J., Poon W., McPhee N., et al. Randomized study of percutaneous endoscopic gastrostomy versus nasogastric tubes for enteral feeding in head and neck cancer patients treated with (chemo)radiation. J Med Imaging Radiat Oncol 2008, 52:503-510.
65. Salas S., Baumstarck-Barrau K., Alfonsi M., et al. Impact of the prophylactic gastrostomy for unresectable squamous cell head and neck carcinomas treated with radio-chemotherapy on quality of life: Prospective randomized trial. Radiother Oncol 2009, 93:503-509.
66. Niv Y., Abuksis G. Indications for percutaneous endoscopic gastrostomy insertion: ethical aspects. Dig Dis 2002, 20:253-256.
67. Madhoun M.F., Blankenship M.M., Blankenship D.M., Krempl G.A., Tierney W.M. Prophylactic PEG placement in head and neck cancer: how many feeding tubes are unused (and unnecessary)?. World J Gastroenterol 2011, 17:1004-1008.
68. Wang J., Liu M., Liu C., Ye Y., Huang G. Percutaneous endoscopic gastrostomy versus nasogastric tube feeding for patients with head and neck cancer: a systematic review. J Radiat Res 2014, 55:559-567.
69. Clavel S., Fortin B., Després P., et al. Enteral feeding during chemoradiotherapy for advanced head-and-neck cancer: a single-institution experience using a reactive approach. Int J Radiat Oncol Biol Phys 2011, 79:763-769.
70. Sheth C.H., Sharp S., Walters E.R. Enteral feeding in head and neck cancer patients at a UK cancer centre. J Hum Nutr Diet 2013, 26:421-428.
71. Corry J., Poon W., McPhee N., et al. Prospective study of percutaneous endoscopic gastrostomy tubes versus nasogastric tubes for enteral feeding in patients with head and neck cancer undergoing (chemo)radiation. Head Neck 2009, 31(7):867-876.
72. Oozeer N.B., Corsar K., Glore R.J., Penney S., Patterson J., Paleri V. The impact of enteral feeding route on patient-reported long term swallowing outcome after chemoradiation for head and neck cancer. Oral Oncol 2011, 47:980-983.
73. Shike M. Nutrition therapy for the cancer patient. Hematol Oncol Clin North Am 1996, 10:221-234.
74. Bozzetti F., Arends J., Lundholm K., Micklewright A., Zurcher G., Muscaritoli M. ESPEN. ESPEN Guidelines on Parenteral Nutrition: non-surgical oncology. Clin Nutr 2009, 28:445-454.
75. Ryu J., Nam B.H., Jung Y.S. Clinical outcomes comparing parenteral and nasogastric tube nutrition after laryngeal and pharyngeal cancer surgery. Dysphagia 2009, 24:378-386.
76. Scolapio J.S., Picco M.F., Tarrosa V.B. Enteral versus parenteral nutrition: the patient's preference. J Parenter Enteral Nutr 2002, 26:248-250.
77. Colasanto J.M., Prasad P., Nash M.A., Decker R.H., Wilson L.D. Nutritional support of patients undergoing radiation therapy for head and neck cancer. Oncology (Williston Park) 2005, 19:371-379.
78. Ruiz Garcia V., López-Briz E., Carbonell Sanchis R., Gonzalvez Perales J.L., Bort-Marti S. Megestrol acetate for treatment of anorexia-cachexia syndrome. Cochrane Database Syst Rev 2013, 3:CD004310.
79. Lundholm K., Gunnebo L., Korner U., et al. Effects by daily long term provision of ghrelin to unselected weight-losing cancer patients: a randomized double-blind study. Cancer 2010, 116:2044-2052.
80. Fietkau R., Lewitzki V., Kuhnt T., et al. A disease-specific enteral nutrition formula improves nutritional status and functional performance in patients with head and neck and esophageal cancer undergoing chemoradiotherapy: results of a randomized, controlled, multicenter trial. Cancer 2013, 119:3343-3353.
81. Zilbermint M.F., Dobs A.S. Nonsteroidal selective androgen receptor modulator Ostarine in cancer cachexia. Future Oncol 2009, 5:1211-1220.
82. Solheim T.S., Fearon K.C., Blum D., Kaasa S. Non-steroidal anti-inflammatory treatment in cancer cachexia: a systematic literature review. Acta Oncol 2013, 52:6-17.
83. Mantovani G. Randomised phase III clinical trial of 5 different arms of treatment on 332 patients with cancer cachexia. Eur Rev Med Pharmacol Sci 2010, 14:292-301.