Brain derived neurotrophic factor (BDNF) and autism spectrum disorders (ASD) in childhood

European Journal of Paediatric Neurology

Volumn 19, Issue 4, 2015, Pages 411-414

  Bryn, V ^a   Halvorsen, B ^b   Ueland, T ^b   Isaksen, J ^a   Kolkova, K ^c   Ravn, K ^c   Skjeldal, O H ^d  

^a INNLANDET HOSPITAL TRUST   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c University of Copenhagen   (Denmark)

^d UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Autism spectrum disorders; Brain derived neurotrophic factor; Val66Met

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BIOLOGICAL MARKER; BRAIN-DERIVED NEUROTROPHIC FACTOR, HUMAN;

ARTICLE; AUTISM; CHILD; CLINICAL ASSESSMENT; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HEALTH SURVEY; HUMAN; INTELLECTUAL IMPAIRMENT; MAJOR CLINICAL STUDY; MALE; NORWAY; PRIORITY JOURNAL; ADOLESCENT; BLOOD; DEMOGRAPHY;

ADOLESCENT; AUTISM SPECTRUM DISORDER; BIOMARKERS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CHILD; DEMOGRAPHY; FEMALE; HUMANS; MALE; NORWAY;

EID: 84931563161     PISSN: 10903798     EISSN: 15322130     Source Type: Journal    
DOI: 10.1016/j.ejpn.2015.03.005     Document Type: Article

References (27)

1. J. Isaksen Observed prevalence of autism spectrum disorders in two Norwegian counties doi:10.1016 Eur J Pediatr Neurology 17 1 January 2013 68 76
2. P. Suren, I.J. Bakken, and H. Aase Autism spectrum disorder, ADHD, epilepsi and cerebral palsy in Norwegian children Pediatrics 130 2012 e152 e158
3. E. Fombonne Epidemiology of pervasive developmental disorders Pediatr Re 65 6 2009 591 598
4. D.K. Binder, and H.E. Scharfman Brain- derived neurotrophic factor Grow Factors 22 3 2004 123 131
5. G.M. Anderson Genetics of childhood disorders:XLV. Autism, part 4: Serotonin in autism J Am Acad Child Adolesc Psychiatry 41 12 2002 1513 1516
6. Q.B. Zhang, L.F. Jiang, L.Y. Kong, and Y.J. Lu Serum Brain-derived neurotrophic factor levels in Chinese children with autism spectrum disorders: a pilot study Int.J.Dev Neurosci 37 2014 65 68
7. T. Nickl-Jockschat, and T.M. Michel The role of neurotrophic factors in autism Mol Psychiatr 16 2011 478 490
8. S. Ricci Altered cytokine and BDNF levels in Autism spectrum disorders Neurotox Res 24 2013 491 501
9. K.L.P. Garcia Altered balance of proteolytic isoforms of Pro Brain-derived neurotrophic factor in autism Neuropathol Exp Neurol 71 4 2012 289 297
10. C.Y. Correia Increased BDNF levels and NTRK2 gene association suggest a disruption of BDNF/TrkB signalling in autism, Genes Brain Behav 9 2010 841 848
11. M. Mansour, A. Mohamed, H. Azam, and M. Henedy Brain derived neurotrophic factor in autism Curr Psychiatry 17 1 2010 23 29
12. P.G. Nelson, T. Kudo, and E.Y. Song Selected neurotrophins, neuropeptides and cytokines: developmental trajectory and concentrations in neonatal blood of children with autism or Down syndrome Int J Dev Neurosci 24 1 2006 73 80
13. M.W. Abdallah Neonatal levels of neurotrophic factors and risk of autism spectrum disorders Acta Psychiatr Scand 128 1 2013 61 69
14. M. Hashimoto, M.S. Keshavan, and N.J. Minshew Correlation between BDNF and severety of autistic features Mol Pdychiatry 3 2007 141 147
15. World Health Organization International statistical classification of diseases and related health problems 2008 ed 2009 World Health Organization 10 rev.Geneva
16. J. Isaksen Children with autism spectrum disorders-The importance of medical investigations Eur J Paediatr Neurol 17 2013 68 76
17. K. Nisshimura, K. Nakamura, and A. Anitha Genetic analysis of the brain-derived neurotrophic factor (BDNF) gene in autism Biochemi Biophys Res Commun 356 1 2007 200 2006
18. K.B. Nelson Neuropeptides and neurotrophins in neonatal blood of children with autism or mental retardation Ann Neurol 49 2001 597 606
19. K. Miyazaki, N. Narita, and R. Sakuta Serum neurotrophin concentrations in autism and mental retardation: a pilot study Brain Dev 26 5 2004 292 295
20. Y.A.L. Ayadhi Relationship between sonic Hedgehog Protein, brain-derived neurotrophic factor and oxidative stress in autism spectrum disorders Neurochem Res 37 2 2012 394 400
21. A.M. Connolly Brain derived and autoantibodies to neural antigens in sera of children with autistic spectrum disorders, Landau-Kleftner syndrome and epilepsy Biol Psychiatry 59 4 2006 354 363
22. J.M. Ramsey, P.C. Guest, and J.A.C. Broek Identification of an age-dependent biomarker signature in children and adolescents with autism spectrum disorders Mol Autism 4 2013 27
23. U.E. Lang The met allele of the BDNF Val66Met polymorphism is associated with increased BDNF serum concentrations Mol Psychaitr 14 2009 120 122
24. B.B. Zeev The common BDNF polymorphism may be a modifier of disease severity in Rett syndrome Neurology 72 2009 1242 1247
25. L.E. Duncan, K.E. Huchison, G. Carey, and W.E. Craighead Variation in brain-derived neurotrophic factor (BDNF) gene is associated with symptoms of depression J Affect Disord 115 2008 215 219
26. D.M. Halepoto, S. Bashir, and L. Al-Aydahi Possible role of brain- derived neurotrophic factor (BDNF) in autism disorder: current status J Collegue Physicians Surg Pak 24 4 2014 274 278
27. NCCLS Collection, transport and processing of blood specimens for coagulation testing and general performance of coagulation assays Standards NCCL 3rd ed. 1998 NCCLS, 940 West Valley Road Wayne, PA, USA