Angiotensin-(1-7) attenuates angiotensin II-induced ICAM-1, VCAM-1, and MCP-1 expression via the MAS receptor through suppression of P38 and NF-κB pathways in HUVECs

Cellular Physiology and Biochemistry

Volumn 35, Issue 6, 2015, Pages 2472-2482

  Liang, Bin ^a   Wang, Xin ^a   Zhang, Nana ^a   Yang, Huiyu ^a   Bai, Rui ^a   Liu, Ming ^a   Bian, Yunfei ^a   Xiao, Chuanshi ^a   Yang, Zhiming ^a  

^a SHANXI MEDICAL UNIVERSITY   (China)

Author keywords

Angiotensin II; Angiotensin (1 7); Atherosclerosis; ICAM 1; MCP 1; VCAM 1

Indexed keywords

ANGIOTENSIN II; ANGIOTENSIN[1-7]; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; SYNAPTOTAGMIN I; VASCULAR CELL ADHESION MOLECULE 1; VON WILLEBRAND FACTOR; ANGIOTENSIN I; ANGIOTENSIN I (1-7); CCL2 PROTEIN, HUMAN; G PROTEIN COUPLED RECEPTOR; I KAPPA B; NF-KAPPAB INHIBITOR ALPHA; ONCOPROTEIN; PEPTIDE FRAGMENT; PROTO-ONCOGENE PROTEINS C-MAS-1;

ARTICLE; ATHEROSCLEROSIS; DISEASE COURSE; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INFLAMMATORY DISEASE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN TRANSPORT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; WESTERN BLOTTING; CELL CULTURE; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION;

ANGIOTENSIN I; ANGIOTENSIN II; CELLS, CULTURED; CHEMOKINE CCL2; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; I-KAPPA B PROTEINS; INTERCELLULAR ADHESION MOLECULE-1; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84931336442     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000374047     Document Type: Article

References (33)

1. Ross R: Atherosclerosis-an inflammatory disease. N Engl J Med 1999;340:115-126.
2. Libby P, Ridker PM, Maseri A: Inflammation and atherosclerosis. Circulation 2002;105:1135-1143.
3. Blankenberg S, Barbaux S, Tiret L: Adhesion molecules and atherosclerosis. Atherosclerosis 2003;170:191-203.
4. Gu L, Okada Y, Clinton SK, Gerard C, Sukhova GK, Libby P, Rollins BJ: Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice. Mol Cell 1998;2:275-281.
5. Hillis GS, Flapan AD: Cell adhesion molecules in cardiovascular disease: a clinical perspective. Heart 1998;79:429-431.
6. Han J, Lee JD, Bibbs L, Ulevitch RJ: A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 1994;265:808-811.
7. Pearson G, Robinson F, Beers Gibson T, Xu BE, Karandikar M, Berman K, Cobb MH: Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev 2001;22:153-183.
8. Monaco C, Andreakos E, Kiriakidis S, Mauri C, Bicknell C, Foxwell B, Cheshire N, Paleolog E, Feldmann M: Canonical pathway of nuclear factor kappa B activation selectively regulates proinflammatory and prothrombotic responses in human atherosclerosis. Proc Natl Acad Sci U S A 2004;101:5634-5639.
9. Dou L, Lu Y, Shen T, Huang X, Man Y, Wang S, Li J: Panax notogingseng saponins suppress RAGE/MAPK signaling and NF-kappaB activation in apolipoprotein-E-deficient atherosclerosis-prone mice. Cell Physiol Biochem 2012; 9:875-882.
10. Lu Y, Zhu X, Liang GX, Cui RR, Liu Y, Wu SS, Liang QH, Liu GY, Jiang Y, Liao XB, Xie H, Zhou HD, Wu XP, Yuan LQ, Liao EY: Apelin-APJ induces ICAM-1, VCAM-1 and MCP-1 expression via NF-kappaB/JNK signal pathway in human umbilical vein endothelial cells. Amino Acids 2012;43:2125-2136.
11. Qian C, Schoemaker RG, van Gilst WH, Roks AJ: The role of the renin-angiotensin-aldosterone system in cardiovascular progenitor cell function. Clin Sci (Lond) 2009;116:301-314.
12. Pacurari M, Kafoury R, Tchounwou PB, Ndebele K: The Renin-Angiotensin-aldosterone system in vascular inflammation and remodeling. Int J Inflam 2014;2014:689360.
13. Chae YJ, Kim CH, Ha TS, Hescheler J, Ahn HY, Sachinidis A: Epigallocatechin-3-O-gallate inhibits the angiotensin II-induced adhesion molecule expression in human umbilical vein endothelial cell via inhibition of MAPK pathways. Cell Physiol Biochem 2007;20:859-866.
14. Costanzo A, Moretti F, Burgio VL, Bravi C, Guido F, Levrero M, Puri PL: Endothelial activation by angiotensin II through NFkappaB and p38 pathways: Involvement of NFkappaB-inducible kinase (NIK), free oxygen radicals, and selective inhibition by aspirin. J Cell Physiol 2003;195:402-410.
15. Takahashi M, Suzuki E, Takeda R, Oba S, Nishimatsu H, Kimura K, Nagano T, Nagai R, Hirata Y: Angiotensin II and tumor necrosis factor-alpha synergistically promote monocyte chemoattractant protein-1 expression: roles of NF-kappaB, p38, and reactive oxygen species. Am J Physiol Heart Circ Physiol 2008;294:H2879-2888.
16. Suzuki E, Satonaka H, Nishimatsu H, Oba S, Takeda R, Omata M, Fujita T, Nagai R, Hirata Y: Myocyte enhancer factor 2 mediates vascular inflammation via the p38-dependent pathway. Circ Res 2004;95:42-49.
17. Jiang F, Yang J, Zhang Y, Dong M, Wang S, Zhang Q, Liu FF, Zhang K, Zhang C: Angiotensin-converting enzyme 2 and angiotensin 1-7: novel therapeutic targets. Nat Rev Cardiol 2014;11:413-426.
18. Santos RA: Angiotensin-(1-7). Hypertension 2014;63:1138-1147.
19. Freeman EJ, Chisolm GM, Ferrario CM, Tallant EA: Angiotensin-(1-7) inhibits vascular smooth muscle cell growth. Hypertension 1996;28:104-108.
20. Loot AE, Roks AJ, Henning RH, Tio RA, Suurmeijer AJ, Boomsma F, van Gilst WH: Angiotensin-(1-7) attenuates the development of heart failure after myocardial infarction in rats. Circulation 2002;105:1548-1550.
21. Tallant EA, Clark MA: Molecular mechanisms of inhibition of vascular growth by angiotensin-(1-7). Hypertension 2003;42:574-579.
22. Wang L, Hu X, Zhang W, Tian F: Angiotensin (1-7) ameliorates angiotensin II-induced inflammation by inhibiting LOX-1 expression. Inflamm Res 2013;62:219-228.
23. Chen XL, Tummala PE, Olbrych MT, Alexander RW, Medford RM: Angiotensin II induces monocyte chemoattractant protein-1 gene expression in rat vascular smooth muscle cells. Circ Res 1998;83:952-959.
24. Pastore L, Tessitore A, Martinotti S, Toniato E, Alesse E, Bravi MC, Ferri C, Desideri G, Gulino A, Santucci A: Angiotensin II stimulates intercellular adhesion molecule-1 (ICAM-1) expression by human vascular endothelial cells and increases soluble ICAM-1 release in vivo. Circulation 1999;100:1646-1652.
25. Zhang F, Hu Y, Xu Q, Ye S. Different effects of angiotensin II and angiotensin-(1-7) on vascular smooth muscle cell proliferation and migration. PLoS One 2010;5:e12323.
26. Yang JM1, Dong M, Meng X, Zhao YX, Yang XY, Liu XL, Hao PP, Li JJ, Wang XP, Zhang K, Gao F, Zhao XQ, Zhang MX, Zhang Y, Zhang C. Angiotensin-(1-7) dose-dependently inhibits atherosclerotic lesion formation and enhances plaque stability by targeting vascular cells. Arterioscler Thromb Vasc Biol 2013;33:1978-85.
27. Liang B, Wang X, Bian Y, Yang H, Liu M, Bai R, Yang Z, Xiao C: Angiotensin-(1-7) upregulates expression of ABCA1 and ABCG1 through the Mas receptor via the liver X receptor alpha signaling pathway in THP-1 macrophages treated with Angiotensin II. Clin Exp Pharmacol Physiol 2014;41:1023-1030.
28. Liang B, Wang X, Yan F, Bian YF, Liu M, Bai R, Yang HY, Zhang NN, Yang ZM, Xiao CS: Angiotensin-(1-7) upregulates (ATP-binding cassette transporter A1) ABCA1 expression through cyclic AMP signaling pathway in RAW 264.7 macrophages. Eur Rev Med Pharmacol Sci 2014;18:985-991.
29. Torres L, Serna E, Bosch A, Zaragoza R, Garcia C, Miralles VJ, Sandoval J, Vina JR, Garcia-Trevijano ER: NF-kB as node for signal amplification during weaning. Cell Physiol Biochem 2011;28:833-846.
30. Ghosh S, Hayden MS: New regulators of NF-kappaB in inflammation. Nat Rev Immunol 2008;8:837-848.
31. Perkins ND: Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat Rev Mol Cell Biol 2007;8:49-62.
32. Xie S, Liu B, Fu S, Wang W, Yin Y, Li N, Chen W, Liu J, Liu D: GLP-2 suppresses LPS-induced inflammation in macrophages by inhibiting ERK phosphorylation and NF-kappaB activation. Cell Physiol Biochem 2014;34:590-602.
33. Santos RA, Simoes e Silva AC, Maric C, Silva DM, Machado RP, de Buhr I, Heringer-Walther S, Pinheiro SV, Lopes MT, Bader M et al: Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc Natl Acad Sci U S A 2003;100:8258-8263.