Downregulation of miR-19a exhibits inhibitory effects on metastatic renal cell carcinoma by targeting PIK3CA and inactivating Notch signaling in vitro

Oncology Reports

Volumn 34, Issue 2, 2015, Pages 739-746

  Xiao, Wei ^a   Gao, Zhiyong ^a   Duan, Yixing ^a   Yuan, Wuxiong ^a   Ke, Yang ^a  

^a HUNAN PROVINCIAL PEOPLE S HOSPITAL   (China)

Author keywords

Metastasis; MiR 19a; Notch signaling; PIK3CA; Renal cell carcinoma

Indexed keywords

GELATINASE B; JAGGED1; MICRORNA; MICRORNA 19A; NOTCH RECEPTOR; NOTCH1 RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE CATALYTIC ALPHA SUBUNIT; UNCLASSIFIED DRUG; MIRN19 MICRORNA, HUMAN; PIK3CA PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ARTICLE; CELL INVASION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; GAIN OF FUNCTION MUTATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INTRACELLULAR SIGNALING; KIDNEY METASTASIS; LOSS OF FUNCTION MUTATION; METASTASIS INHIBITION; MIGRATION INHIBITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; UPREGULATION; BIOSYNTHESIS; GENETICS; KIDNEY CARCINOMA; METASTASIS; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CARCINOMA, RENAL CELL; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICRORNAS; NEOPLASM METASTASIS; PHOSPHATIDYLINOSITOL 3-KINASES; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 84931330021     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2015.4041     Document Type: Article

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