BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 23, 2015, Pages E3067-E3074

  Mizui, Toshiyuki ^a,b   Ishikawa, Yasuyuki ^b,c,d   Kumanogoh, Haruko ^a,b   Lume, Maria ^e   Matsumoto, Tomoya ^b,f   Hara, Tomoko ^a,b   Yamawaki, Shigeto ^b,f   Takahashi, Masami ^b,g   Shiosaka, Sadao ^b,c   Itami, Chiaki ^h   Uegaki, Koichi ^a,b   Saarma, Mart ^e   Kojima, Masami ^a,b,i  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^d Muroran Institute of Technology   (Japan)

^e UNIVERSITY OF HELSINKI   (Finland)

^f HIROSHIMA UNIVERSITY   (Japan)

^g KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^h SAITAMA MEDICAL UNIVERSITY   (Japan)

ⁱ OSAKA UNIVERSITY   (Japan)

Author keywords

Growth factor; Neuron; Polymorphism; Pro peptide; Synaptic plasticity

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; METHIONINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROTROPHIN RECEPTOR P75; PEPTIDE; PROTEIN; PROTEIN GLUN2B; PROTEIN PRECURSOR; UNCLASSIFIED DRUG; VALINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENDOCYTOSIS; HIPPOCAMPUS; HUMAN; LONG TERM DEPRESSION; MEMORY; MOLECULAR BIOLOGY; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN POLYMORPHISM; RAT; SYNAPTIC TRANSMISSION; ANIMAL; GENETIC POLYMORPHISM; GENETICS; KNOCKOUT MOUSE; PHYSIOLOGY;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; HIPPOCAMPUS; HUMANS; LONG-TERM SYNAPTIC DEPRESSION; METHIONINE; MICE; MICE, KNOCKOUT; POLYMORPHISM, GENETIC; PROTEIN PRECURSORS; RATS; VALINE;

EID: 84931291556     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1422336112     Document Type: Article

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