Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome

Antimicrobial Agents and Chemotherapy

Volumn 59, Issue 5, 2015, Pages 2849-2854

  Schedlbauer, Andreas ^a   Kaminishi, Tatsuya ^a,b   Ochoa Lizarralde, Borja ^a   Dhimole, Neha ^a,b   Zhou, Shu ^b,d   López Alonso, Jorge P ^a   Connell, Sean R ^a,c   Fucini, Paola ^a,b,c  

^a CIC BIOGUNE   (Spain)

^b GOETHE UNIVERSITY   (Germany)

^c BASQUE FOUNDATION FOR SCIENCE   (Spain)

^d STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL RNA; RNA 16S; TIGECYCLINE; MINOCYCLINE; PROTEIN BINDING;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL CELL; DRUG ANALYSIS; DRUG BINDING SITE; DRUG CONFORMATION; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN QUATERNARY STRUCTURE; RIBOSOME SUBUNIT; THERMUS THERMOPHILUS; X RAY CRYSTALLOGRAPHY; ANALOGS AND DERIVATIVES; DRUG EFFECTS; METABOLISM; PROTEIN SECONDARY STRUCTURE; RIBOSOME;

CRYSTALLOGRAPHY, X-RAY; MINOCYCLINE; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RIBOSOMES; RNA, RIBOSOMAL, 16S; THERMUS THERMOPHILUS;

EID: 84931282026     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.04895-14     Document Type: Article

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