Platelet actin nodules are podosome-like structures dependent on Wiskott-Aldrich syndrome protein and ARP2/3 complex

Nature Communications

Volumn 6, Issue , 2015, Pages

  Poulter, Natalie S ^a   Pollitt, Alice Y ^a   Davies, Amy ^a   Malinova, Dessislava ^b   Nash, Gerard B ^a   Hannon, Mike J ^a   Pikramenou, Zoe ^a   Rappoport, Joshua Z ^c   Hartwig, John H ^d   Owen, Dylan M ^e   Thrasher, Adrian J ^b   Watson, Stephen P ^a   Thomas, Steven G ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c NORTHWESTERN UNIVERSITY   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN RELATED PROTEIN 2-3 COMPLEX; INTEGRIN; PHOSPHOPROTEIN; TALIN; VINCULIN; WISKOTT ALDRICH SYNDROME PROTEIN; ACTIN; WAS PROTEIN, HUMAN; WAS PROTEIN, MOUSE;

ADHESION; BLOOD; IMMUNE RESPONSE; PROTEIN; RODENT; SIGNALING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING TENDENCY; CELL INTERACTION; CELL MEMBRANE; CELL SPREADING; CONTROLLED STUDY; ELECTRON MICROSCOPY; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; NORMAL HUMAN; PROTEIN DEPLETION; PROTEIN STRUCTURE; SHEAR RATE; THROMBOCYTE; THROMBOCYTE AGGREGATION; WISKOTT ALDRICH SYNDROME; ACTIN FILAMENT; ANIMAL; BLOOD; FLUORESCENCE IMAGING; FLUORESCENCE MICROSCOPY; GENETICS; KNOCKOUT MOUSE; METABOLISM; PODOSOME; ULTRASTRUCTURE;

ACTIN CYTOSKELETON; ACTIN-RELATED PROTEIN 2-3 COMPLEX; ACTINS; ANIMALS; BLOOD PLATELETS; HUMANS; MICE; MICE, KNOCKOUT; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; OPTICAL IMAGING; PLATELET AGGREGATION; PODOSOMES; TALIN; VINCULIN; WISKOTT-ALDRICH SYNDROME; WISKOTT-ALDRICH SYNDROME PROTEIN;

EID: 84931275261     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8254     Document Type: Article

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