Surface modification of microparticles causes differential uptake responses in normal and tumoral human breast epithelial cells

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Patiño, Tania ^a   Soriano, Jorge ^a   Barrios, Lleonard ^a   Ibáñez, Elena ^a   Nogués, Carme ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMATERIAL; CANCER ANTIBODY; IMMUNOGLOBULIN G; NANOPARTICLE; POLYETHYLENEIMINE;

BREAST NEOPLASMS; CHEMISTRY; DRUG DELIVERY SYSTEM; FEMALE; HUMAN; METABOLISM; PATHOLOGY; PROCEDURES; TUMOR CELL LINE;

ANTIBODIES, NEOPLASM; BREAST NEOPLASMS; CELL LINE, TUMOR; COATED MATERIALS, BIOCOMPATIBLE; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; IMMUNOGLOBULIN G; NANOPARTICLES; POLYETHYLENEIMINE;

EID: 84931265126     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep11371     Document Type: Article

References (48)

1. Carregal-Romero, S. et al. Multiplexed sensing and imaging with colloidal nano-and microparticles. Annu. Rev. Anal. Chem. (Palo Alto. Calif). 6, 53-81 (2013
2. Cederquist, K. B., Dean, S. L. & Keating, C. D. Encoded anisotropic particles for multiplexed bioanalysis. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 2, 578-600 (2010
3. Sen, T. & Bruce, I. J. Surface engineering of nanoparticles in suspension for particle based bio-sensing. Sci. Rep. 2, 564 (2012
4. Anker, J. N. et al. Biosensing with plasmonic nanosensors. Nat. Mater. 7, 442-53 (2008
5. Yu, M. K., Park, J. & Jon, S. Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy. Theranostics 2, 3-44 (2012
6. Sanna, V., Pala, N. & Sechi, M. Targeted therapy using nanotechnology: Focus on cancer. Int. J. Nanomedicine 9, 467-483 (2014
7. Gu, F. X. et al. Targeted nanoparticles for cancer therapy. Nano Today 2, 14-21 (2007
8. Jain, N. K., Mishra, V. & Mehra, N. K. Targeted drug delivery to macrophages. Expert Opin. Drug Deliv. 10, 353-67 (2013
9. Caldorera-Moore, M. & Peppas, N. a. Micro-and nanotechnologies for intelligent and responsive biomaterial-based medical systems. Adv. Drug Deliv. Rev. 61, 1391-401 (2009
10. Cai, Y., Chen, Y., Hong, X., Liu, Z. & Yuan, W. Porous microsphere and its applications. Int. J. Nanomedicine 8, 1111-20 (2013
11. Mura, S., Nicolas, J. & Couvreur, P. Stimuli-responsive nanocarriers for drug delivery. Nat. Mater. 12, 991-1003 (2013
12. Zauner, W., Farrow, N. a. & Haines, a. M. In vitro uptake of polystyrene microspheres: Effect of particle size, cell line and cell density. J. Control. Release 71, 39-51 (2001
13. Rejman, J., Oberle, V., Zuhorn, I. S. & Hoekstra, D. Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis. Biochem. J. 377, 159-69 (2004
14. Pacheco, P., White, D. & Sulchek, T. Effects of microparticle size and Fc density on macrophage phagocytosis. PLoS One 8, e60989 (2013
15. Shang, L., Nienhaus, K. & Nienhaus, G. U. Engineered nanoparticles interacting with cells: Size matters. J. Nanobiotechnology 12, 5 (2014
16. Barua, S. et al. Particle shape enhances specificity of antibody-displaying nanoparticles. Proc. Natl. Acad. Sci. USA 110, 3270-5 (2013
17. Gratton, S. E. a. et al. The effect of particle design on cellular internalization pathways. Proc. Natl. Acad. Sci. USA 105, 11613-8 (2008
18. Saha, K. et al. Surface functionality of nanoparticles determines cellular uptake mechanisms in mammalian cells. Small 9, 300-5 (2013
19. Dausend, J. et al. Uptake mechanism of oppositely charged fluorescent nanoparticles in HeLa cells. Macromol. Biosci. 8, 1135-43 (2008
20. Fröhlich, E. The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles. Int. J. Nanomedicine 7, 5577-91 (2012
21. Thiele, L., Merkle, H. P. & Walter, E. Phagocytosis and phagosomal fate of surface-modified microparticles in dendritic cells and macrophages. Pharm. Res. 20, 221-8 (2003
22. Harush-Frenkel, O., Debotton, N., Benita, S. & Altschuler, Y. Targeting of nanoparticles to the clathrin-mediated endocytic pathway. Biochem. Biophys. Res. Commun. 353, 26-32 (2007
23. Patiño, T., Nogués, C., Ibáñez, E. & Barrios, L. Enhancing microparticle internalization by nonphagocytic cells through the use of noncovalently conjugated polyethyleneimine. Int. J. Nanomedicine 7, 5671-5682 (2012
24. Boussif, O. et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine. Proc. Natl. Acad. Sci. 92, 7297-7301 (1995
25. Yu, J.-H., Quan, J.-S., Huang, J., Nah, J.-W. & Cho, C.-S. Degradable poly(amino ester) based on poly(ethylene glycol) dimethacrylate and polyethylenimine as a gene carrier: Molecular weight of PEI affects transfection efficiency. J. Mater. Sci. Mater. Med. 20, 2501-10 (2009
26. Xiao, Y. et al. Dynamics and mechanisms of quantum dot nanoparticle cellular uptake. J. Nanobiotechnology 8, 13 (2010
27. Oliveira, S., Heukers, R., Sornkom, J., Kok, R. J. & Van Bergen En Henegouwen, P. M. P. Targeting tumors with nanobodies for cancer imaging and therapy. J. Control. Release 172, 607-617 (2013
28. Patino, T. et al. Multifunctional gold nanorods for selective plasmonic photothermal therapy in pancreatic cancer cells using ultra-short pulse near-infrared laser irradiation. Nanoscale 7, 5328-5337 (2015
29. Conniot, J. et al. Cancer immunotherapy: Nanodelivery approaches for immune cell targeting and tracking. Front. Chem. 2, 105 (2014
30. Loureiro, J. A., Gomes, B., Coelho, M. A. N., do Carmo Pereira, M. & Rocha, S. Targeting nanoparticles across the blood-brain barrier with monoclonal antibodies. Nanomedicine (Lond). 9, 709-722 (2014
31. Ferrati, S. et al. Inter-endothelial transport of microvectors using cellular shuttles and tunneling nanotubes. Small 8, 3151-60 (2012
32. Palankar, R. et al. Controlled intracellular release of peptides from microcapsules enhances antigen presentation on MHC class I molecules. Small 5, 2168-76 (2009
33. Sukhorukov, G. B. et al. Multifunctionalized polymer microcapsules: Novel tools for biological and pharmacological applications. Small 3, 944-955 (2007
34. Delcea, M. et al. Multicompartmental Micro-and Nanocapsules: Hierarchy and Applications in Biosciences. Macromol. Biosci. 10, 465-474 (2010
35. Salonen, J. et al. Mesoporous silicon microparticles for oral drug delivery: Loading and release of five model drugs. J. Control. Release 108, 362-374 (2005
36. Skandrani, N. et al. Lipid nanocapsules functionalized with polyethyleneimine for plasmid DNA and drug co-delivery and cell imaging. Nanoscale 6, 7379-90 (2014
37. Kasturi, S. P., Sachaphibulkij, K. & Roy, K. Covalent conjugation of polyethyleneimine on biodegradable microparticles for delivery of plasmid DNA vaccines. Biomaterials 26, 6375-6385 (2005
38. Ateh, D. D. et al. The intracellular uptake of CD95 modified paclitaxel-loaded poly(lactic-co-glycolic acid) microparticles. Biomaterials 32, 8538-47 (2011
39. McBain, S. C., Yiu, H. H. P., El Haj, a. & Dobson, J. Polyethyleneimine functionalized iron oxide nanoparticles as agents for DNA delivery and transfection. J. Mater. Chem. 17, 2561 (2007
40. Neu, M., Fischer, D. & Kissel, T. Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives. J. Gene Med. 7, 992-1009 (2005
41. Qiu, Y. et al. Surface chemistry and aspect ratio mediated cellular uptake of Au nanorods. Biomaterials 31, 7606-19 (2010
42. Wang, F. et al. The biomolecular corona is retained during nanoparticle uptake and protects the cells from the damage induced by cationic nanoparticles until degraded in the lysosomes. Nanomedicine 9, 1159-68 (2013
43. Yan, Y. et al. Differential roles of the protein corona in the cellular uptake of nanoporous polymer particles by monocyte and macrophage cell lines. ACS Nano 7, 10960-70 (2013
44. Macia, E. et al. Dynasore, a cell-permeable inhibitor of dynamin. Dev. Cell 10, 839-50 (2006
45. Barr, D. J., Ostermeyer-Fay, A. G., Matundan, R. A. & Brown, D. A. Clathrin-independent endocytosis of ErbB2 in geldanamycintreated human breast cancer cells. J. Cell Sci. 121, 3155-3166 (2008
46. Vaidyanath, A. et al. Enhanced internalization of ErbB2 in SK-BR-3 cells with multivalent forms of an artificial ligand. J. Cell. Mol. Med. 15, 2525-2538 (2011
47. Lim, J. P. & Gleeson, P. A. Macropinocytosis : An endocytic pathway for internalising large gulps. Immunol. Cell Biol. 89, 836-843 (2011
48. Bousiff, O. et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: POLYETHYLENIMINE. 92, 7297-7301 (1995).