메뉴 건너뛰기




Volumn 1317, Issue , 2015, Pages 87-105

iCaspase 9 suicide gene system

Author keywords

Allodepleted T cells; AP1903; Dimerizer; GvHD; Inducible caspase 9; Safety switch; Suicide gene

Indexed keywords

BINDING PROTEIN; CASPASE 9; INDUCIBLE CASPASE 9; RIMIDUCID; UNCLASSIFIED DRUG; CD3 ANTIGEN; FIBRONECTIN; IMMUNOTOXIN; INTERLEUKIN 2; OKT 3; RECOMBINANT PROTEIN; RETRONECTIN;

EID: 84931262138     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4939-2727-2_6     Document Type: Article
Times cited : (19)

References (24)
  • 1
    • 0028820386 scopus 로고
    • Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor
    • Walter EA, Greenberg PD, Gilbert MJ et al (1995) Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor. N Engl J Med 333: 1038–1044
    • (1995) N Engl J Med , vol.333 , pp. 1038-1044
    • Walter, E.A.1    Greenberg, P.D.2    Gilbert, M.J.3
  • 2
    • 0032170108 scopus 로고    scopus 로고
    • Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus-induced lymphoma in allogeneic transplant recipients
    • Rooney CM, Smith CA, Ng CY et al (1998) Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus-induced lymphoma in allogeneic transplant recipients. Blood 92:1549–1555
    • (1998) Blood , vol.92 , pp. 1549-1555
    • Rooney, C.M.1    Smith, C.A.2    Ng, C.Y.3
  • 3
    • 0037174674 scopus 로고    scopus 로고
    • Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
    • Dudley ME, Wunderlich JR, Robbins PF et al (2002) Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science 298:850–854
    • (2002) Science , vol.298 , pp. 850-854
    • Dudley, M.E.1    Wunderlich, J.R.2    Robbins, P.F.3
  • 4
    • 0030843493 scopus 로고    scopus 로고
    • HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia
    • Bonini C, Ferrari G, Verzeletti S et al (1997) HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia. Science 276:1719–1724
    • (1997) Science , vol.276 , pp. 1719-1724
    • Bonini, C.1    Ferrari, G.2    Verzeletti, S.3
  • 5
    • 34249688206 scopus 로고    scopus 로고
    • Antitumor effects of HSV-TK–engineered donor lymphocytes after allogeneic stem-cell transplantation
    • Ciceri F, Bonini C, Marktel S et al (2007) Antitumor effects of HSV-TK–engineered donor lymphocytes after allogeneic stem-cell transplantation. Blood 109:4698–4707
    • (2007) Blood , vol.109 , pp. 4698-4707
    • Ciceri, F.1    Bonini, C.2    Marktel, S.3
  • 6
    • 0035161228 scopus 로고    scopus 로고
    • Administration of herpes simplex-thymidine kinase-expressing donor T cells with a T-celldepleted allogeneic marrow graft
    • Tiberghien P, Ferrand C, Lioure B et al (2001) Administration of herpes simplex-thymidine kinase-expressing donor T cells with a T-celldepleted allogeneic marrow graft. Blood 97: 63–72
    • (2001) Blood , vol.97 , pp. 63-72
    • Tiberghien, P.1    Ferrand, C.2    Lioure, B.3
  • 7
    • 65349157330 scopus 로고    scopus 로고
    • Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (The TK007 trial): A non-randomised phase I-II study
    • Ciceri F, Bonini C, Stanghellini MT et al (2009) Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study. Lancet Oncol 10:489–500
    • (2009) Lancet Oncol , vol.10 , pp. 489-500
    • Ciceri, F.1    Bonini, C.2    Stanghellini, M.T.3
  • 8
    • 34249748406 scopus 로고    scopus 로고
    • The potential immunogenicity of the TK suicide gene does not prevent full clinical benefi t associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies
    • Traversari C, Marktel S, Magnani Z et al (2007) The potential immunogenicity of the TK suicide gene does not prevent full clinical benefi t associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies. Blood 109:4708–4715
    • (2007) Blood , vol.109 , pp. 4708-4715
    • Traversari, C.1    Marktel, S.2    Magnani, Z.3
  • 9
    • 0035174929 scopus 로고    scopus 로고
    • Molecular mechanism for ganciclovir resistance in human T lymphocytes transduced with retroviral vectors carrying the herpes simplex virus thymidine kinase gene
    • Garin MI, Garrett E, Tiberghien P et al (2001) Molecular mechanism for ganciclovir resistance in human T lymphocytes transduced with retroviral vectors carrying the herpes simplex virus thymidine kinase gene. Blood 97:122–129
    • (2001) Blood , vol.97 , pp. 122-129
    • Garin, M.I.1    Garrett, E.2    Tiberghien, P.3
  • 11
    • 0026030568 scopus 로고
    • Chemistry and biology of the immunophilins and their immunosuppressive ligands
    • Schreiber SL (1991) Chemistry and biology of the immunophilins and their immunosuppressive ligands. Science 251:283–287
    • (1991) Science , vol.251 , pp. 283-287
    • Schreiber, S.L.1
  • 12
    • 0026643141 scopus 로고
    • Identifi cation of calcineurin as a key signalling enzyme in T-lymphocyte activation
    • Clipstone NA, Crabtree GR (1992) Identifi cation of calcineurin as a key signalling enzyme in T-lymphocyte activation. Nature 357:695–697
    • (1992) Nature , vol.357 , pp. 695-697
    • Clipstone, N.A.1    Crabtree, G.R.2
  • 13
    • 13144276290 scopus 로고    scopus 로고
    • Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specifi city
    • Clackson T, Yang W, Rozamus LW et al (1998) Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specifi city. Proc Natl Acad Sci U S A 95:10437–10442
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 10437-10442
    • Clackson, T.1    Yang, W.2    Rozamus, L.W.3
  • 14
    • 0034919257 scopus 로고    scopus 로고
    • Intravenous safety and pharmacokinetics of a novel dimerizer drug, AP1903, in healthy volunteers
    • Iuliucci JD, Oliver SD, Morley S et al (2001) Intravenous safety and pharmacokinetics of a novel dimerizer drug, AP1903, in healthy volunteers. J Clin Pharmacol 41:870–879
    • (2001) J Clin Pharmacol , vol.41 , pp. 870-879
    • Iuliucci, J.D.1    Oliver, S.D.2    Morley, S.3
  • 15
    • 19344365874 scopus 로고    scopus 로고
    • An inducible caspase 9 safety switch for T-cell therapy
    • Straathof KC, Pulè MA, Yotnda P et al (2005) An inducible caspase 9 safety switch for T-cell therapy. Blood 105(11):4247–4254
    • (2005) Blood , vol.105 , Issue.11 , pp. 4247-4254
    • Straathof, K.C.1    Pulè, M.A.2    Yotnda, P.3
  • 16
    • 34447310075 scopus 로고    scopus 로고
    • Inducible caspase 9 suicide gene to improve the safety of allodepleted T cells after haploidentical stem cell transplantation
    • Tey SK, Dotti G, Rooney CM, Heslop HE, Brenner MK (2007) Inducible caspase 9 suicide gene to improve the safety of allodepleted T cells after haploidentical stem cell transplantation. Biol Blood Marrow Transplant 13(8):913–924
    • (2007) Biol Blood Marrow Transplant , vol.13 , Issue.8 , pp. 913-924
    • Tey, S.K.1    Dotti, G.2    Rooney, C.M.3    Heslop, H.E.4    Brenner, M.K.5
  • 17
    • 80455162464 scopus 로고    scopus 로고
    • Inducible apoptosis as a safety switch for adoptive cell therapy
    • Di Stasi A, Tey SK, Dotti G et al (2011) Inducible apoptosis as a safety switch for adoptive cell therapy. N Engl J Med 365(18):1673–1683
    • (2011) N Engl J Med , vol.365 , Issue.18 , pp. 1673-1683
    • Di Stasi, A.1    Tey, S.K.2    Dotti, G.3
  • 18
    • 0033562349 scopus 로고    scopus 로고
    • Depletion of alloreactive T cells by a specifi c anti-interleukin-2 receptor p55 chain immunotoxin does not impair in vitro antileukemia and antiviral activity
    • Montagna D, Yvon E, Calcaterra V et al (1999) Depletion of alloreactive T cells by a specifi c anti-interleukin-2 receptor p55 chain immunotoxin does not impair in vitro antileukemia and antiviral activity. Blood 93(10):3550–3557
    • (1999) Blood , vol.93 , Issue.10 , pp. 3550-3557
    • Montagna, D.1    Yvon, E.2    Calcaterra, V.3
  • 19
    • 0037072113 scopus 로고    scopus 로고
    • Immune reconstitution without graft-versus-host disease after haemopoietic stem-cell transplantation: A phase 1/2 study
    • André-Schmutz I, Le Deist F, Hacein-Bey- Abina S et al (2002) Immune reconstitution without graft-versus-host disease after haemopoietic stem-cell transplantation: a phase 1/2 study. Lancet 360(9327):130–137
    • (2002) Lancet , vol.360 , Issue.9327 , pp. 130-137
    • André-Schmutz, I.1    Le Deist, F.2    Hacein-Bey- Abina, S.3
  • 20
    • 0141790817 scopus 로고    scopus 로고
    • Selective depletion of donor alloreactive T cells without loss of antiviral or antileukemic responses
    • Amrolia PJ, Muccioli-Casadei G, Yvon E et al (2003) Selective depletion of donor alloreactive T cells without loss of antiviral or antileukemic responses. Blood 102(6):2292–2299
    • (2003) Blood , vol.102 , Issue.6 , pp. 2292-2299
    • Amrolia, P.J.1    Muccioli-Casadei, G.2    Yvon, E.3
  • 21
    • 33748692890 scopus 로고    scopus 로고
    • Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation
    • Amrolia PJ, Muccioli-Casadei G, Huls H et al (2006) Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation. Blood 108(6):1797–1808
    • (2006) Blood , vol.108 , Issue.6 , pp. 1797-1808
    • Amrolia, P.J.1    Muccioli-Casadei, G.2    Huls, H.3
  • 22
    • 7344268577 scopus 로고    scopus 로고
    • Clinical trials with an anti-CD25 ricin A-chain experimental and immunotoxin (RFT5- SMPT- dgA) in Hodgkin’s lymphoma
    • Schnell R, Vitetta E, Schindler J et al (1998) Clinical trials with an anti-CD25 ricin A-chain experimental and immunotoxin (RFT5- SMPT- dgA) in Hodgkin’s lymphoma. Leuk Lymphoma 30(5–6):525–537
    • (1998) Leuk Lymphoma , vol.30 , Issue.56 , pp. 525-537
    • Schnell, R.1    Vitetta, E.2    Schindler, J.3
  • 23
    • 84902654151 scopus 로고    scopus 로고
    • Longterm outcome and immune reconstitution after haploidentical stem cell transplant in recipients of allodepleted-T-cells expressing the inducible caspase-9 safety transgene
    • Zhou X, Di Stasi A, Tey SK et al (2014) Longterm outcome and immune reconstitution after haploidentical stem cell transplant in recipients of allodepleted-T-cells expressing the inducible caspase-9 safety transgene. Blood 123(25): 3895–3905
    • (2014) Blood , vol.123 , Issue.25 , pp. 3895-3905
    • Zhou, X.1    Di Stasi, A.2    Tey, S.K.3
  • 24
    • 0014385564 scopus 로고
    • Isolation of mononuclear cells and granulocytes from human blood
    • Böyum A (1968) Isolation of mononuclear cells and granulocytes from human blood. Scand J Clin Lab Invest Suppl 97:77–89
    • (1968) Scand J Clin Lab Invest Suppl , vol.97 , pp. 77-89
    • Böyum, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.