-
1
-
-
0034461768
-
Drug-like properties and the causes of poor solubility and poor permeability
-
11274893 1:CAS:528:DC%2BD3MXitF2ksrc%3D
-
Lipinski CA. Drug-like properties and the causes of poor solubility and poor permeability. J Pharmacol Toxicol Methods. 2000;44(1):235-49.
-
(2000)
J Pharmacol Toxicol Methods
, vol.44
, Issue.1
, pp. 235-249
-
-
Lipinski, C.A.1
-
3
-
-
84878874855
-
Pharmaceutical nanotechnology for oral delivery of anticancer drugs
-
23220325 1:CAS:528:DC%2BC3sXht1Gmtbo%3D
-
Mei L, Zhang Z, Zhao L, Huang L, Yang XL, Tang J, et al. Pharmaceutical nanotechnology for oral delivery of anticancer drugs. Adv Drug Deliv Rev. 2013;65(6):880-90.
-
(2013)
Adv Drug Deliv Rev
, vol.65
, Issue.6
, pp. 880-890
-
-
Mei, L.1
Zhang, Z.2
Zhao, L.3
Huang, L.4
Yang, X.L.5
Tang, J.6
-
4
-
-
0029080002
-
Particle size reduction for improvement of oral bioavailability of hydrophobic drugs: I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs
-
Liversidge GG, Cundy KC. Particle size reduction for improvement of oral bioavailability of hydrophobic drugs: I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs. Int J Pharm. 1995;1:91-7.
-
(1995)
Int J Pharm
, vol.1
, pp. 91-97
-
-
Liversidge, G.G.1
Cundy, K.C.2
-
5
-
-
0035937599
-
Nanosuspensions as particulate drug formulations in therapy: Rationale for development and what we can expect for the future
-
Müller RH, Jacobs C, Kayser O. Nanosuspensions as particulate drug formulations in therapy: rationale for development and what we can expect for the future. Adv Drug Deliv Rev. 2001;1:3-19.
-
(2001)
Adv Drug Deliv Rev
, vol.1
, pp. 3-19
-
-
Müller, R.H.1
Jacobs, C.2
Kayser, O.3
-
6
-
-
38949117575
-
Approaches for the development of solid and semi-solid lipid-based formulations
-
Jannin V, Musakhanian J, Marchaud D. Approaches for the development of solid and semi-solid lipid-based formulations. Adv Drug Deliv Rev. 2008;6:734-46.
-
(2008)
Adv Drug Deliv Rev
, vol.6
, pp. 734-746
-
-
Jannin, V.1
Musakhanian, J.2
Marchaud, D.3
-
7
-
-
0019437945
-
Case report - Suspected anaphylactic reaction to Cremophor El
-
Strachan EB. Case report - suspected anaphylactic reaction to Cremophor El. SAAD Dig. 1981;9:209.
-
(1981)
SAAD Dig
, vol.9
, pp. 209
-
-
Strachan, E.B.1
-
8
-
-
34249087392
-
PLGA nanoparticles for oral delivery of cyclosporine: Nephrotoxicity and pharmacokinetic studies in comparison to Sandimmune Neoral
-
17399839 1:CAS:528:DC%2BD2sXlsFaisr0%3D
-
Italia JL, Bhatt DK, Bhardwaj V, Tikoo K, Kumar MN. PLGA nanoparticles for oral delivery of cyclosporine: nephrotoxicity and pharmacokinetic studies in comparison to Sandimmune Neoral. J Control Release. 2007;119(2):197-206.
-
(2007)
J Control Release
, vol.119
, Issue.2
, pp. 197-206
-
-
Italia, J.L.1
Bhatt, D.K.2
Bhardwaj, V.3
Tikoo, K.4
Kumar, M.N.5
-
9
-
-
0028903583
-
Improved absorption of cyclosporin A from a new microemulsion formulation: Implications for dosage and monitoring
-
Bökenkamp A, Offner G, Hoyer PF, Vester U, Wonigeit K, Brodehl J. Improved absorption of cyclosporin A from a new microemulsion formulation: implications for dosage and monitoring. Pediatr Nephrol. 1995;2:196-8.
-
(1995)
Pediatr Nephrol
, vol.2
, pp. 196-198
-
-
Bökenkamp, A.1
Offner, G.2
Hoyer, P.F.3
Vester, U.4
Wonigeit, K.5
Brodehl, J.6
-
10
-
-
0027141121
-
Solvent dependent conformation and hydrogen bounding capacity of cyclosporin A: Evidence from partition coefficient and molecular dynamics simula-tions
-
Taylor NE, Mark AE, Vallat P, Brunne RM, Testa B, Van Gunteren WF. Solvent dependent conformation and hydrogen bounding capacity of cyclosporin A: evidence from partition coefficient and molecular dynamics simula-tions. J Med Chem. 1993;24:3753-64.
-
(1993)
J Med Chem
, vol.24
, pp. 3753-3764
-
-
Taylor, N.E.1
Mark, A.E.2
Vallat, P.3
Brunne, R.M.4
Testa, B.5
Van Gunteren, W.F.6
-
11
-
-
0031810775
-
Cyclosporine monitoring in patients with renal transplants: Two- or three-point methods that estimate area under the curve are superior to trough levels in predicting drug exposure
-
9631924 1:CAS:528:DyaK1cXjvVChsL8%3D
-
Primmett DR, Levine M, Kovarik JM, Mueller EA, Keown PA. Cyclosporine monitoring in patients with renal transplants: two- or three-point methods that estimate area under the curve are superior to trough levels in predicting drug exposure. Ther Drug Monit. 1998;20(3):276-83.
-
(1998)
Ther Drug Monit
, vol.20
, Issue.3
, pp. 276-283
-
-
Primmett, D.R.1
Levine, M.2
Kovarik, J.M.3
Mueller, E.A.4
Keown, P.A.5
-
12
-
-
3042551382
-
Bioavailability and pharmacokinetics of cyclosporine A-loaded pH-sensitive nanoparticles for oral administration
-
15212874 1:CAS:528:DC%2BD2cXkvF2itrY%3D
-
Wang XQ, Dai JD, Chen Z, Zhang T, Xia GM, Nagai T, et al. Bioavailability and pharmacokinetics of cyclosporine A-loaded pH-sensitive nanoparticles for oral administration. J Control Release. 2004;97(3):421-9.
-
(2004)
J Control Release
, vol.97
, Issue.3
, pp. 421-429
-
-
Wang, X.Q.1
Dai, J.D.2
Chen, Z.3
Zhang, T.4
Xia, G.M.5
Nagai, T.6
-
13
-
-
0029562489
-
Lipid microemulsions for improving drug dissolution and oral absorption: Physical and biopharmaceutical aspects
-
Constantinides PP. Lipid microemulsions for improving drug dissolution and oral absorption: physical and biopharmaceutical aspects. Pharm Res. 1995;11:1561-72.
-
(1995)
Pharm Res
, vol.11
, pp. 1561-1572
-
-
Constantinides, P.P.1
-
14
-
-
0034880214
-
Cremophor EL: The drawbacks and advantages of vehicle selection for drug formulation
-
Gelderblom H, Verweij J, Nooter K, Sparreboom A. Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation. Eur J Cancer. 2001;13:1590-98.
-
(2001)
Eur J Cancer
, vol.13
, pp. 1590-1598
-
-
Gelderblom, H.1
Verweij, J.2
Nooter, K.3
Sparreboom, A.4
-
15
-
-
0032542499
-
Complement activation by Cremophor EL as a possible contributor to hypersensitivity to paclitaxel: An in vitro study
-
Szebeni J, Muggia FM, Alving CR. Complement activation by Cremophor EL as a possible contributor to hypersensitivity to paclitaxel: an In vitro study. J Natl Cancer Inst. 1997;4:300-6.
-
(1997)
J Natl Cancer Inst
, vol.4
, pp. 300-306
-
-
Szebeni, J.1
Muggia, F.M.2
Alving, C.R.3
-
16
-
-
84855826196
-
Efficacy and toxicological studies of cremophor EL free alternative paclitaxel formulation
-
Utreja P, Jain S, Yadav S, Khandhuja KL, Tiwary AK. Efficacy and toxicological studies of cremophor EL free alternative paclitaxel formulation. Curr Drug Saf. 2011;5:329-38.
-
(2011)
Curr Drug Saf
, vol.5
, pp. 329-338
-
-
Utreja, P.1
Jain, S.2
Yadav, S.3
Khandhuja, K.L.4
Tiwary, A.K.5
-
17
-
-
77951189574
-
Pharmacokinetics and enhanced oral bioavailability in beagle dogs of cyclosporine A encapsulated in glyceryl monooleate/poloxamer 407 cubic nanoparticles
-
20161984 1:CAS:528:DC%2BD1MXhs1SitLzO 2819904
-
Lai J, Lu Y, Yin Z, Hu F, Wu W. Pharmacokinetics and enhanced oral bioavailability in beagle dogs of cyclosporine A encapsulated in glyceryl monooleate/poloxamer 407 cubic nanoparticles. Int J Nanomedicine. 2010;5:13-23.
-
(2010)
Int J Nanomedicine
, vol.5
, pp. 13-23
-
-
Lai, J.1
Lu, Y.2
Yin, Z.3
Hu, F.4
Wu, W.5
-
18
-
-
0026035063
-
Therapeutic monitoring for cyclosporine: Difficulties in establishing a therapeutic window
-
Bowers LD. Therapeutic monitoring for cyclosporine: difficulties in establishing a therapeutic window. Clin Biochem. 1991;1:81-7.
-
(1991)
Clin Biochem
, vol.1
, pp. 81-87
-
-
Bowers, L.D.1
-
19
-
-
79951707504
-
Therapeutic window analysis of the neuroprotective effects of cyclosporine a after traumatic brain injury
-
Sullivan PG, Sebastian AH, Hall ED. Therapeutic window analysis of the neuroprotective effects of cyclosporine a after traumatic brain injury. J Neurotrauma. 2011;2:311-8.
-
(2011)
J Neurotrauma
, vol.2
, pp. 311-318
-
-
Sullivan, P.G.1
Sebastian, A.H.2
Hall, E.D.3
-
20
-
-
0021280574
-
Cyclosporine-associated chronic nephropathy
-
Myers BD, Ross J, Newton L, Luetscher J, Perlroth M. Cyclosporine-associated chronic nephropathy. N Engl J Med. 1984;11:699-705.
-
(1984)
N Engl J Med
, vol.11
, pp. 699-705
-
-
Myers, B.D.1
Ross, J.2
Newton, L.3
Luetscher, J.4
Perlroth, M.5
-
22
-
-
0029562489
-
Lipid microemulsions for improving drug dissolution and oral absorption: Physical and biopharmaceutical aspects
-
8592652 1:CAS:528:DyaK2MXpslCqsrs%3D
-
Constantinides PP. Lipid microemulsions for improving drug dissolution and oral absorption: physical and biopharmaceutical aspects. Pharm Res. 1995;12(11):1561-72.
-
(1995)
Pharm Res
, vol.12
, Issue.11
, pp. 1561-1572
-
-
Constantinides, P.P.1
-
23
-
-
0026791626
-
Principles of emulsion formation
-
1:CAS:528:DyaK3sXht1ShsQ%3D%3D
-
Walstra P. Principles of emulsion formation. Chem Eng Sci. 1993;48(2):333-49.
-
(1993)
Chem Eng Sci
, vol.48
, Issue.2
, pp. 333-349
-
-
Walstra, P.1
-
24
-
-
0028329964
-
Improved dose linearity of cyclosporine pharmacokinetics from a microemulsion formulation
-
8165192 1:CAS:528:DyaK2cXhslegs7s%3D
-
Mueller E, Kovarik J, van Bree J, Tetzloff W, Grevel J, Kutz K. Improved dose linearity of cyclosporine pharmacokinetics from a microemulsion formulation. Pharm Res. 1994;11(2):301-4.
-
(1994)
Pharm Res
, vol.11
, Issue.2
, pp. 301-304
-
-
Mueller, E.1
Kovarik, J.2
Van Bree, J.3
Tetzloff, W.4
Grevel, J.5
Kutz, K.6
-
25
-
-
0344012523
-
Development of a supersaturable SEDDS (S-SEDDS) formulation of paclitaxel with improved oral bioavailability
-
14603484 1:CAS:528:DC%2BD3sXps1OisLY%3D
-
Gao P, Rush BD, Pfund WP, Huang T, Bauer JM, Morozowich W, et al. Development of a supersaturable SEDDS (S-SEDDS) formulation of paclitaxel with improved oral bioavailability. J Pharm Sci. 2003;92(12):2386-98.
-
(2003)
J Pharm Sci
, vol.92
, Issue.12
, pp. 2386-2398
-
-
Gao, P.1
Rush, B.D.2
Pfund, W.P.3
Huang, T.4
Bauer, J.M.5
Morozowich, W.6
-
26
-
-
0037407282
-
Human jejunal permeability of cyclosporin a: Influence of surfactants on P-glycoprotein efflux in caco-2 cells
-
12751630 1:CAS:528:DC%2BD3sXjtFKgs7c%3D
-
Chiu Y-Y, Higaki K, Neudeck B, Barnett J, Welage L, Amidon G. Human jejunal permeability of cyclosporin a: influence of surfactants on P-glycoprotein efflux in caco-2 cells. Pharm Res. 2003;20(5):749-56.
-
(2003)
Pharm Res
, vol.20
, Issue.5
, pp. 749-756
-
-
Chiu, Y.-Y.1
Higaki, K.2
Neudeck, B.3
Barnett, J.4
Welage, L.5
Amidon, G.6
-
27
-
-
58049193000
-
Microemulsions: A novel approach to enhanced drug delivery
-
19075911 1:CAS:528:DC%2BD1cXhtlWnsr7O
-
Talegaonkar S, Azeem A, Ahmad FJ, Khar RK, Pathan SA, Khan ZI. Microemulsions: a novel approach to enhanced drug delivery. Recent Pat Drug Deliv Formul. 2008;2(3):238-57.
-
(2008)
Recent Pat Drug Deliv Formul
, vol.2
, Issue.3
, pp. 238-257
-
-
Talegaonkar, S.1
Azeem, A.2
Ahmad, F.J.3
Khar, R.K.4
Pathan, S.A.5
Khan, Z.I.6
-
28
-
-
84876406117
-
Detergent-mediated protein aggregation
-
23466535 1:CAS:528:DC%2BC3sXkt12qu7o%3D
-
Neale C, Ghanei H, Holyoake J, Bishop RE, Prive GG, Pomes R. Detergent-mediated protein aggregation. Chem Phys Lipids. 2013;169:72-84.
-
(2013)
Chem Phys Lipids
, vol.169
, pp. 72-84
-
-
Neale, C.1
Ghanei, H.2
Holyoake, J.3
Bishop, R.E.4
Prive, G.G.5
Pomes, R.6
-
29
-
-
84905509966
-
Amphiphilic surfactants and amphiphilic polymers: Principles of molecular assembly
-
ACS Symposium Series. 1070: American Chemical Society
-
Nagarajan R. Amphiphilic surfactants and amphiphilic polymers: principles of molecular assembly. Amphiphiles: molecular assembly and applications. ACS Symposium Series. 1070: American Chemical Society; 2011; 1-22.
-
(2011)
Amphiphiles: Molecular Assembly and Applications
, pp. 1-22
-
-
Nagarajan, R.1
-
30
-
-
84858001781
-
Use of nanoparticles and microparticles in the formation and stabilization of food emulsions
-
1:CAS:528:DC%2BC38XjtlOmsr4%3D
-
Dickinson E. Use of nanoparticles and microparticles in the formation and stabilization of food emulsions. Trends Food Sci Technol. 2012;24(1):4-12.
-
(2012)
Trends Food Sci Technol
, vol.24
, Issue.1
, pp. 4-12
-
-
Dickinson, E.1
-
32
-
-
79960047579
-
Outstanding stability of poorly-protected pickering emulsions. Trends in colloid and interface science XXIII
-
Springer Berlin Heidelberg
-
Destribats M, Ravaine S, Heroguez V, Leal-Calderon F, Schmitt V. Outstanding stability of poorly-protected pickering emulsions. Trends in colloid and interface science XXIII. Progress in Colloid and Polymer Science. 137: Springer Berlin Heidelberg; 2010. p. 13-8.
-
(2010)
Progress in Colloid and Polymer Science
, vol.137
, pp. 13-18
-
-
Destribats, M.1
Ravaine, S.2
Heroguez, V.3
Leal-Calderon, F.4
Schmitt, V.5
-
33
-
-
79955044994
-
Silica-lipid hybrid microcapsules: Influence of lipid and emulsifier type on in vitro performance
-
21371543 1:CAS:528:DC%2BC3MXkslektrg%3D
-
Lim LH, Tan A, Simovic S, Prestidge CA. Silica-lipid hybrid microcapsules: Influence of lipid and emulsifier type on in vitro performance. Int J Pharm. 2011;409(1-2):297-306.
-
(2011)
Int J Pharm
, vol.409
, Issue.1-2
, pp. 297-306
-
-
Lim, L.H.1
Tan, A.2
Simovic, S.3
Prestidge, C.A.4
-
34
-
-
84857214169
-
Assembling nanoparticle coatings to improve the drug delivery performance of lipid based colloids
-
22159191 1:CAS:528:DC%2BC38Xhslarsrw%3D
-
Simovic S, Barnes TJ, Tan A, Prestidge CA. Assembling nanoparticle coatings to improve the drug delivery performance of lipid based colloids. Nanoscale. 2012;4(4):1220-30.
-
(2012)
Nanoscale
, vol.4
, Issue.4
, pp. 1220-1230
-
-
Simovic, S.1
Barnes, T.J.2
Tan, A.3
Prestidge, C.A.4
-
35
-
-
77950591046
-
Silica nanoparticles to control the lipase-mediated digestion of lipid-based oral delivery systems
-
20063867 1:CAS:528:DC%2BC3cXnvFWjtw%3D%3D
-
Tan A, Simovic S, Davey AK, Rades T, Boyd BJ, Prestidge CA. Silica nanoparticles to control the lipase-mediated digestion of lipid-based oral delivery systems. Mol Pharm. 2010;7(2):522-32.
-
(2010)
Mol Pharm
, vol.7
, Issue.2
, pp. 522-532
-
-
Tan, A.1
Simovic, S.2
Davey, A.K.3
Rades, T.4
Boyd, B.J.5
Prestidge, C.A.6
-
36
-
-
34250853524
-
Nanoparticle layers controlling drug release from emulsions
-
17329085 1:CAS:528:DC%2BD2sXntF2mu7c%3D
-
Simovic S, Prestidge CA. Nanoparticle layers controlling drug release from emulsions. Eur J Pharm Biopharm. 2007;67(1):39-47.
-
(2007)
Eur J Pharm Biopharm
, vol.67
, Issue.1
, pp. 39-47
-
-
Simovic, S.1
Prestidge, C.A.2
-
37
-
-
84873653899
-
Surfactant-free high internal phase emulsions stabilized by cellulose nanocrystals
-
Feb 11
-
Capron I, Cathala B. Surfactant-free high internal phase emulsions stabilized by cellulose nanocrystals. Biomacromolecules. 2013 Feb 11;14(2):291-6.
-
(2013)
Biomacromolecules
, vol.14
, Issue.2
, pp. 291-296
-
-
Capron, I.1
Cathala, B.2
-
38
-
-
58949098421
-
Extended release of lidocaine from linker-based lecithin microemulsions
-
19010404 1:CAS:528:DC%2BD1MXhsFertb8%3D
-
Yuan JS, Acosta EJ. Extended release of lidocaine from linker-based lecithin microemulsions. Int J Pharm. 2009;368(1-2):63-71.
-
(2009)
Int J Pharm
, vol.368
, Issue.1-2
, pp. 63-71
-
-
Yuan, J.S.1
Acosta, E.J.2
-
39
-
-
76749131979
-
Impact of emulsion-based drug delivery systems on intestinal permeability and drug release kinetics
-
19850092 1:CAS:528:DC%2BC3cXhs1Sgtr0%3D
-
Buyukozturk F, Benneyan JC, Carrier RL. Impact of emulsion-based drug delivery systems on intestinal permeability and drug release kinetics. J Control Release. 2010;142(1):22-30.
-
(2010)
J Control Release
, vol.142
, Issue.1
, pp. 22-30
-
-
Buyukozturk, F.1
Benneyan, J.C.2
Carrier, R.L.3
|