Neuronal polarization

Development (Cambridge)

Volumn 142, Issue 12, 2015, Pages 2088-2093

  Takano, Tetsuya ^a   Xu, Chundi ^a   Funahashi, Yasuhiro ^a   Namba, Takashi ^a   Kaibuchi, Kozo ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Axon outgrowth; Cellular asymmetry; Dendrite outgrowth; Multipolar to bipolar transition; Neuronal polarity

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN 3; PROTEIN KINASE C; RHO FACTOR; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SEMAPHORIN 3A; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA; WNT5A PROTEIN;

ACTIN FILAMENT; ARTICLE; BRAIN CORTEX; CELL ELONGATION; CELL POLARITY; DENDRITE; HIPPOCAMPAL NEURONAL CULTURE; IN VITRO STUDY; INTRACELLULAR SIGNALING; NERVE CELL; NERVE FIBER; NERVE FIBER GROWTH; NEURITE; NEURONAL POLARIZATION; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; ANIMAL; BRAIN; CYTOLOGY; HUMAN; METABOLISM; MOUSE; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; AXONS; BRAIN; CELL POLARITY; DENDRITES; HUMANS; MICE; NEURONS; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION;

EID: 84931060038     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.114454     Document Type: Article

References (64)

1. Aizawa, H., Wakatsuki, S., Ishii, A., Moriyama, K., Sasaki, Y., Ohashi, K., Sekine-Aizawa, Y., Sehara-Fujisawa, A., Mizuno, K., Goshima, Y. et al. (2001). Phosphorylation of cofilin by LIM-kinase is necessary for semaphorin 3A-induced growth cone collapse. Nat. Neurosci. 4, 367-373
2. Arimura, N. and Kaibuchi, K. (2007). Neuronal polarity: from extracellular signals to intracellular mechanisms. Nat. Rev. Neurosci. 8, 194-205
3. Arimura, N., Kimura, T., Nakamuta, S., Taya, S., Funahashi, Y., Hattori, A., Shimada, A., Ménager, C., Kawabata, S., Fujii, K. et al. (2009). Anterograde transport of TrkB in axons is mediated by direct interaction with Slp1 and Rab27. Dev. Cell 16, 675-686
4. Barnes, A. P. and Polleux, F. (2009). Establishment of axon-dendrite polarity in developing neurons. Annu. Rev. Neurosci. 32, 347-381
5. Barnes, A. P., Lilley, B. N., Pan, Y. A., Plummer, L. J., Powell, A. W., Raines, A. N., Sanes, J. R. and Polleux, F. (2007). LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons. Cell 129, 549-563
6. Bony, G., Szczurkowska, J., Tamagno, I., Shelly, M., Contestabile, A. and Cancedda, L. (2013). Non-hyperpolarizing GABAB receptor activation regulates neuronal migration and neurite growth and specification by cAMP/LKB1. Nat. Commun. 4, 1800
7. Bradke, F. and Dotti, C. G. (1999). The role of local actin instability in axon formation. Science 283, 1931-1934
8. Cheng, P.-L. and Poo, M.-M. (2012). Early events in axon/dendrite polarization. Annu. Rev. Neurosci. 35, 181-201
9. Cheng, P.-L., Song, A.-H., Wong, Y.-H., Wang, S., Zhang, X. and Poo, M.-M. (2011). Self-amplifying autocrine actions of BDNF in axon development. Proc. Natl. Acad. Sci. USA 108, 18430-18435
10. Conde, C., Arias, C., Robin, M., Li, A., Saito, M., Chuang, J. Z., Nairn, A. C., Sung, C. H. and Caceres, A. (2010). Evidence for the involvement of Lfc and Tctex-1 in axon formation. J. Neurosci. 30, 6793-6800
11. Craig, A. M. and Banker, G. (1994). Neuronal polarity. Annu. Rev. Neurosci. 17, 267-310
12. Da Silva, J. S., Medina, M., Zuliani, C., Di Nardo, A., Witke, W. and Dotti, C. G. (2003). RhoA/ROCK regulation of neuritogenesis via profilin IIa-mediated control of actin stability. J. Cell Biol. 162, 1267-1279
13. Doe, C. Q. and Kaibuchi, K. (2011). Neuronal polarity in 2011. Dev. Neurobiol. 71, 401-402
14. Dotti, C. G., Sullivan, C. A. and Banker, G. A. (1988). The establishment of polarity by hippocampal neurons in culture. J. Neurosci. 8, 1454-1468
15. Flynn, K. C., Hellal, F., Neukirchen, D., Jacob, S., Tahirovic, S., Dupraz, S., Stern, S., Garvalov, B. K., Gurniak, C., Shaw, A. E. et al. (2012). ADF/cofilinmediated actin retrograde flow directs neurite formation in the developing brain. Neuron 76, 1091-1107
16. Fukata, M., Nakagawa, M. and Kaibuchi, K. (2003). Roles of Rho-family GTPases in cell polarisation and directional migration. Curr. Opin. Cell Biol. 15, 590-597
17. Funahashi, Y., Namba, T., Nakamuta, S. and Kaibuchi, K. (2014). Neuronal polarization in vivo: growing in a complex environment. Curr. Opin. Neurobiol. 27, 215-223
18. Gärtner, A., Fornasiero, E. F., Munck, S., Vennekens, K., Seuntjens, E., Huttner, W. B., Valtorta, F. and Dotti, C. G. (2012). N-cadherin specifies first asymmetry in developing neurons. EMBO J. 31, 1893-1903
19. Garvalov, B. K., Flynn, K. C., Neukirchen, D., Meyn, L., Teusch, N., Wu, X., Brakebusch, C., Bamburg, J. R. and Bradke, F. (2007). Cdc42 regulates cofilin during the establishment of neuronal polarity. J. Neurosci. 27, 13117-13129
20. Gonzalez-Billault, C., Muñoz-Llancao, P., Henriquez, D. R., Wojnacki, J., Conde, C. and Caceres, A. (2012). The role of small GTPases in neuronal morphogenesis and polarity. Cytoskeleton 69, 464-485
21. Guo, S. and Kemphues, K. J. (1995). par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81, 611-620
22. Hall, A., Paterson, H. F., Adamson, P. and Ridley, A. J. (1993). Cellular responses regulated by rho-related small GTP-binding proteins. Philos. Trans. R. Soc. Lond. B Biol. Sci. 340, 267-271
23. Hatanaka, Y. and Yamauchi, K. (2013). Excitatory cortical neurons with multipolar shape establish neuronal polarity by forming a tangentially oriented axon in the intermediate zone. Cereb. Cortex 23, 105-113
24. Houde, V. P., Ritorto, M. S., Gourlay, R., Varghese, J., Davies, P., Shpiro, N., Sakamoto, K. and Alessi, D. R. (2014). Investigation of LKB1 Ser431 phosphorylation and Cys433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity. Biochem. J. 458, 41-56
25. Inagaki, N., Chihara, K., Arimura, N., Ménager, C., Kawano, Y., Matsuo, N., Nishimura, T., Amano, M. and Kaibuchi, K. (2001). CRMP-2 induces axons in cultured hippocampal neurons. Nat. Neurosci. 4, 781-782
26. Inagaki, N., Toriyama, M. and Sakumura, Y. (2011). Systems biology of symmetry breaking during neuronal polarity formation. Dev. Neurobiol. 71, 584-593
27. Jiang, H., Guo, W., Liang, X. and Rao, Y. (2005). Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3beta and its upstream regulators. Cell 120, 123-135
28. Jossin, Y. and Cooper, J. A. (2011). Reelin, Rap1 and N-cadherin orient the migration of multipolar neurons in the developing neocortex. Nat. Neurosci. 14, 697-703
29. Katayama, K.-I., Melendez, J., Baumann, J. M., Leslie, J. R., Chauhan, B. K., Nemkul, N., Lang, R. A., Kuan, C.-Y., Zheng, Y. and Yoshida, Y. (2011). Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation. Proc. Natl. Acad. Sci. USA 108, 7607-7612
30. Kawano, Y., Yoshimura, T., Tsuboi, D., Kawabata, S., Kaneko-Kawano, T., Shirataki, H., Takenawa, T. and Kaibuchi, K. (2005). CRMP-2 is involved in kinesin-1-dependent transport of the Sra-1/WAVE1 complex and axon formation. Mol. Cell. Biol. 25, 9920-9935
31. Kawauchi, T., Chihama, K., Nabeshima, Y.-i. and Hoshino, M. (2003). The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration. EMBO J. 22, 4190-4201
32. Kawauchi, T., Sekine, K., Shikanai, M., Chihama, K., Tomita, K., Kubo, K.-I., Nakajima, K., Nabeshima, Y.-I. and Hoshino, M. (2010). Rab GTPasesdependent endocytic pathways regulate neuronal migration and maturation through N-cadherin trafficking. Neuron 67, 588-602
33. Kimura, T., Ishiguro, K. and Hisanaga, S.-I. (2014). Physiological and pathological phosphorylation of tau by Cdk5. Front. Mol. Neurosci. 7, 65
34. Kishi, M., Pan, Y. A., Crump, J. G. and Sanes, J. R. (2005). Mammalian SAD kinases are required for neuronal polarization. Science 307, 929-932
35. Kollins, K. M., Hu, J., Bridgman, P. C., Huang, Y. Q. and Gallo, G. (2009). Myosin-II negatively regulates minor process extension and the temporal development of neuronal polarity. Dev. Neurobiol. 69, 279-298
36. Lizcano, J. M., Göransson, O., Toth, R., Deak, M., Morrice, N. A., Boudeau, J., Hawley, S. A., Udd, L., Mäkelä, T. P., Hardie, D. G. et al. (2004). LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/ PAR-1. EMBO J. 23, 833-843
37. Miyamoto, Y., Yamauchi, J., Tanoue, A., Wu, C. and Mobley, W. C. (2006). TrkB binds and tyrosine-phosphorylates Tiam1, leading to activation of Rac1 and induction of changes in cellular morphology. Proc. Natl. Acad. Sci. USA 103, 10444-10449
38. Miyata, T., Kawaguchi, A., Saito, K., Kawano, M., Muto, T. and Ogawa, M. (2004). Asymmetric production of surface-dividing and non-surface-dividing cortical progenitor cells. Development 131, 3133-3145
39. Mori, K., Amano, M., Takefuji, M., Kato, K., Morita, Y., Nishioka, T., Matsuura, Y., Murohara, T. and Kaibuchi, K. (2009). Rho-kinase contributes to sustained RhoA activation through phosphorylation of p190A RhoGAP. J. Biol. Chem. 284, 5067-5076
40. Nakamuta, S., Funahashi, Y., Namba, T., Arimura, N., Picciotto, M. R., Tokumitsu, H., Soderling, T. R., Sakakibara, A., Miyata, T., Kamiguchi, H. et al. (2011). Local application of neurotrophins specifies axons through inositol 1,4,5-trisphosphate, calcium, and Ca2+/calmodulin-dependent protein kinases. Sci. Signal. 4, ra76
41. Nakayama, M., Goto, T. M., Sugimoto, M., Nishimura, T., Shinagawa, T., Ohno, S., Amano, M. and Kaibuchi, K. (2008). Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation. Dev. Cell 14, 205-215
42. Namba, T., Kibe, Y., Funahashi, Y., Nakamuta, S., Takano, T., Ueno, T., Shimada, A., Kozawa, S., Okamoto, M., Shimoda, Y. et al. (2014). Pioneering axons regulate neuronal polarization in the developing cerebral cortex. Neuron 81, 814-829
43. Nishimura, T., Yamaguchi, T., Kato, K., Yoshizawa, M., Nabeshima, Y.-I., Ohno, S., Hoshino, M. and Kaibuchi, K. (2005). PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1. Nat. Cell Biol. 7, 270-277
44. Noctor, S. C., Martínez-Cerdeño, V., Ivic, L. and Kriegstein, A. R. (2004). Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases. Nat. Neurosci. 7, 136-144
45. Pacary, E., Heng, J., Azzarelli, R., Riou, P., Castro, D., Lebel-Potter, M., Parras, C., Bell, D. M., Ridley, A. J., Parsons, M. et al. (2011). Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signaling. Neuron 69, 1069-1084
46. Sapir, T., Shmueli, A., Levy, T., Timm, T., Elbaum, M., Mandelkow, E.-M. and Reiner, O. (2008). Antagonistic effects of doublecortin and MARK2/Par-1 in the developing cerebral cortex. J. Neurosci. 28, 13008-13013
47. Schwamborn, J.C. and Püschel, A.W. (2004).The sequential activity of theGTPases Rap1B and Cdc42 determines neuronal polarity. Nat. Neurosci. 7, 923-929
48. Shelly, M., Cancedda, L., Heilshorn, S., Sumbre, G. and Poo, M.-M. (2007). LKB1/ STRAD promotes axon initiation during neuronal polarization. Cell 129, 565-577
49. Shelly, M., Lim, B. K., Cancedda, L., Heilshorn, S. C., Gao, H. and Poo, M.-M. (2010). Local and long-range reciprocal regulation of cAMP and cGMP in axon/ dendrite formation. Science 327, 547-552
50. Solecki, D. J., Govek, E.-E., Tomoda, T. and Hatten, M. E. (2006). Neuronal polarity in CNS development. Genes Dev. 20, 2639-2647
51. Sun, Y., Fei, T., Yang, T., Zhang, F., Chen, Y.-G., Li, H. and Xu, Z. (2010). The suppression of CRMP2 expression by bone morphogenetic protein (BMP)-SMAD gradient signaling controls multiple stages of neuronal development. J. Biol. Chem. 285, 39039-39050
52. Tahirovic, S. and Bradke, F. (2009). Neuronal polarity. Cold Spring Harb. Perspect. Biol. 1, a001644
53. Tahirovic, S., Hellal, F., Neukirchen, D., Hindges, R., Garvalov, B. K., Flynn, K. C., Stradal, T. E., Chrostek-Grashoff, A., Brakebusch, C. and Bradke, F. (2010). Rac1 regulates neuronal polarization through the WAVE complex. J. Neurosci. 30, 6930-6943
54. Takano, T., Tomomura, M., Yoshioka, N., Tsutsumi, K., Terasawa, Y., Saito, T., Kawano, H., Kamiguchi, H., Fukuda, M. and Hisanaga, S.-i. (2012). LMTK1/AATYK1 is a novel regulator of axonal outgrowth that acts via Rab11 in a Cdk5-dependent manner. J. Neurosci. 32, 6587-6599
55. Takefuji, M., Mori, K., Morita, Y., Arimura, N., Nishimura, T., Nakayama, M., Hoshino, M., Iwamatsu, A., Murohara, T., Kaibuchi, K. et al. (2007). Rhokinase modulates the function of STEF, a Rac GEF, through its phosphorylation. Biochem. Biophys. Res. Commun. 355, 788-794
56. Threadgill, R., Bobb, K. and Ghosh, A. (1997). Regulation of dendritic growth and remodeling by Rho, Rac, and Cdc42. Neuron 19, 625-634
57. Toriyama, M., Kozawa, S., Sakumura, Y. and Inagaki, N. (2013). Conversion of a signal into forces for axon outgrowth through Pak1-mediated shootin1 phosphorylation. Curr. Biol. 23, 529-534
58. Uboha, N. V., Flajolet, M., Nairn, A. C. and Picciotto, M. R. (2007). A calcium-and calmodulin-dependent kinase Ialpha/microtubule affinity regulating kinase 2 signaling cascade mediates calcium-dependent neurite outgrowth. J. Neurosci. 27, 4413-4423
59. Wagner, U., Utton, M., Gallo, J. M. and Miller, C. C. (1996). Cellular phosphorylation of tau by GSK-3 beta influences tau binding to microtubules and microtubule organisation. J. Cell Sci. 109, 1537-1543
60. Wayman, G. A., Kaech, S., Grant, W. F., Davare, M., Impey, S., Tokumitsu, H., Nozaki, N., Banker, G. and Soderling, T. R. (2004). Regulation of axonal extension and growth cone motility by calmodulin-dependent protein kinase I. J. Neurosci. 24, 3786-3794
61. Witte, H. and Bradke, F. (2008). The role of the cytoskeleton during neuronal polarization. Curr. Opin. Neurobiol. 18, 479-487
62. Yi, J. J., Barnes, A. P., Hand, R., Polleux, F. and Ehlers, M. D. (2010). TGF-beta signaling specifies axons during brain development. Cell 142, 144-157
63. Yoshimura, T., Kawano, Y., Arimura, N., Kawabata, S., Kikuchi, A. and Kaibuchi, K. (2005). GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity. Cell 120, 137-149
64. Zuccaro, E., Bergami, M., Vignoli, B., Bony, G., Pierchala, B. A., Santi, S., Cancedda, L. and Canossa, M. (2014).Polarizedexpressionofp75(NTR) specifies axons during development and adult neurogenesis. Cell Rep. 7, 138-152.