Systems biology of symmetry breaking during neuronal polarity formation

Developmental Neurobiology

Volumn 71, Issue 6, 2011, Pages 584-593

  Inagaki, Naoyuki ^a   Toriyama, Michinori ^a   Sakumura, Yuichi ^a  

^a NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

Feedback loop; HRas; Quantitative modeling; Shootin1; Stochasticity

Indexed keywords

ARTICLE; CELL ACTIVITY; CELL DAMAGE; CELL POLARITY; DIFFUSION; MATHEMATICAL MODEL; NERVE CELL; NERVE CELL LESION; NERVE FIBER; NERVE FIBER GROWTH; NEURITE; POLARIZATION; POSITIVE FEEDBACK; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STOCHASTIC MODEL; SYSTEMS BIOLOGY;

ANIMALS; CELL POLARITY; HUMANS; NEURONS; SYSTEMS BIOLOGY;

EID: 79955728549     PISSN: 19328451     EISSN: 10974695     Source Type: Journal    
DOI: 10.1002/dneu.20837     Document Type: Article

References (47)

1. Andersen SS, Bi GQ. 2000. Axon formation: A molecular model for the generation of neuronal polarity. Bioessays 22: 172-179.
2. Arimura N, Kaibuchi K. 2007. Neuronal polarity: From extracellular signals to intracellular mechanisms. Nat Rev Neurosci 8: 194-205.
3. Barnes AP, Polleux F. 2009. Establishment of axon-dendrite polarity in developing neurons. Annu Rev Neurosci 32: 347-381.
4. Bradke F, Dotti CG. 2000a. Differentiated neurons retain the capacity to generate axons from dendrites. Curr Biol 10: 1467-1470.
5. Bradke F, Dotti CG. 2000b. Establishment of neuronal polarity: Lessons from cultured hippocampal neurons. Curr Opin Neurobiol 10: 574-581.
6. Conde C, Caceres A. 2009. Microtubule assembly, organization and dynamics in axons and dendrites. Nat Rev Neurosci 10: 319-332.
7. Craig AM, Banker G. 1994. Neuronal polarity. Annu Rev Neurosci 17: 267-310.
8. Da Silva JS, Dotti CG. 2002. Breaking the neuronal sphere: Regulation of the actin cytoskeleton in neuritogenesis. Nat Rev Neurosci 3: 694-704.
9. Dotti CG, Sullivan CA, Banker GA. 1988. The establishment of polarity by hippocampal neurons in culture. J Neurosci 8: 1454-1468.
10. Fivaz M, Bandara S, Inoue T, Meyer T. 2008. Robust neuronal symmetry breaking by Ras-triggered local positive feedback. Curr Biol 18: 44-50.
11. Goslin K, Banker G. 1989. Experimental observations on the development of polarity by hippocampal neurons in culture. J Cell Biol 108: 1507-1516.
12. Hodgkin AL, Huxley AF. 1952a. The dual effect of membrane potential on sodium conductance in the giant axon of Loligo. J Physiol 116: 497-506.
13. Hodgkin AL, Huxley AF. 1952b. A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol 117: 500-544.
14. Horton AC, Ehlers MD. 2003. Neuronal polarity and trafficking. Neuron 40: 277-295.
15. Iglesias PA, Devreotes PN. 2008. Navigating through models of chemotaxis. Curr Opin Cell Biol 20: 35-40.
16. Inagaki N, Chihara K, Arimura N, Menager C, Kawano Y, Matsuo N, Nishimura T, et al. 2001. CRMP-2 induces axons in cultured hippocampal neurons. Nat Neurosci 4: 781-782.
17. Jacobson C, Schnapp B, Banker GA. 2006. A change in the selective translocation of the kinesin-1 motor domain marks the initial specification of the axon. Neuron 49: 797-804.
18. Jiang H, Guo W, Liang X, Rao Y. 2005. Both the establishment and the maintenance of neuronal polarity require active mechanisms: Critical roles of GSK-3beta and its upstream regulators. Cell 120: 123-135.
19. Kishi M, Pan YA, Crump JG, Sanes JR. 2005. Mammalian SAD kinases are required for neuronal polarization. Science 307: 929-932.
20. Kondo S. 2002. The reaction-diffusion system: A mechanism for autonomous pattern formation in the animal skin. Genes Cells 7: 535-541.
21. Kunda P, Paglini G, Quiroga S, Kosik K, Caceres A. 2001. Evidence for the involvement of Tiam1 in axon formation. J Neurosci 21: 2361-2372.
22. Lamoureux P, Ruthel G, Buxbaum RE, Heidemann SR. 2002. Mechanical tension can specify axonal fate in hippocampal neurons. J Cell Biol 159: 499-508.
23. Lewis J. 2008. From signals to patterns: Space, time, and mathematics in developmental biology. Science 322: 399-403.
24. Lewis J, Ozbudak EM. 2007. Deciphering the somite segmentation clock: Beyond mutants and morphants. Dev Dyn 236: 1410-1415.
25. Meinhardt H. 2008. Hans Meinhardt. Curr Biol 18: R401-R402.
26. Meinhardt H, Gierer A. 2000. Pattern formation by local self-activation and lateral inhibition. Bioessays 22: 753-760.
27. Menager C, Arimura N, Fukata Y, Kaibuchi K. 2004. PIP3 is involved in neuronal polarization and axon formation. J Neurochem 89: 109-118.
28. Mogilner A, Wollman R, Marshall WF. 2006. Quantitative modeling in cell biology: What is it good for? Dev Cell 11: 279-287.
29. Mori T, Wada T, Suzuki T, Kubota Y, Inagaki N. 2007. Singar1, a novel RUN domain-containing protein, suppresses formation of surplus axons for neuronal polarity. J Biol Chem 282: 19884-19893.
30. Nishimura T, Yamaguchi T, Kato K, Yoshizawa M, Nabeshima Y, Ohno S, Hoshino M, et al. 2005. PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1. Nat Cell Biol 7: 270-277.
31. Samuels DC, Hentschel HG, Fine A. 1996. The origin of neuronal polarization: A model of axon formation. Philos Trans R Soc London B Biol Sci 351: 1147-1156.
32. Schwamborn JC, Puschel AW. 2004. The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity. Nat Neurosci 7: 923-929.
33. Shelly M, Lim BK, Cancedda L, Heilshorn SC, Gao H, Poo MM. 2010. Local and long-range reciprocal regulation of cAMP and cGMP in axon/dendrite formation. Science 327: 547-552.
34. Shi SH, Jan LY, Jan YN. 2003. Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity. Cell 112: 63-75.
35. Shimada T, Toriyama M, Uemura K, Kamiguchi H, Sugiura T, Watanabe N, Inagaki N. 2008. Shootin1 interacts with actin retrograde flow and L1-CAM to promote axon outgrowth. J Cell Biol 181: 817-829.
36. Sohrmann M, Peter M. 2003. Polarizing without a c(l)ue. Trends Cell Biol 13: 526-533.
37. Symons MH, Mitchison TJ. 1991. Control of actin polymerization in live and permeabilized fibroblasts. J Cell Biol 114: 503-513.
38. Tahirovic S, Bradke F. 2009. Neuronal polarity. Cold Spring Harb Perspect Biol 1: a001644.
39. Toriyama M, Sakumura Y, Shimada T, Ishii S, Inagaki N. 2010. A diffusion-based neurite length sensing mechanism involved in neuronal symmetry-breaking. Mol Syst Biol 6: 394.
40. Toriyama M, Shimada T, Kim KB, Mitsuba M, Nomura E, Katsuta K, Sakumura Y, et al. 2006. Shootin1: A protein involved in the organization of an asymmetric signal for neuronal polarization. J Cell Biol 175: 147-157.
41. Turing A. 1952. The chemical basis of morphogenesis. Philos Trans R Soc London B Biol Sci 237: 37-72.
42. Wedlich-Soldner R, Li R. 2003. Spontaneous cell polarization: Undermining determinism. Nat Cell Biol 5: 267-270.
43. Weiner OD, Neilsen PO, Prestwich GD, Kirschner MW, Cantley LC, Bourne HR. 2002. A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity. Nat Cell Biol 4: 509-513.
44. Winckler B, Mellman I. 1999. Neuronal polarity: Controlling the sorting and diffusion of membrane components. Neuron 23: 637-640.
45. Yam PT, Wilson CA, Ji L, Hebert B, Barnhart EL, Dye NA, Wiseman PW, et al. 2007. Actin-myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility. J Cell Biol 178: 1207-1221.
46. Yoshimura T, Kawano Y, Arimura N, Kawabata S, Kikuchi A, Kaibuchi K. 2005. GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity. Cell 120: 137-149.
47. Zigmond SH, Levitsky HI, Kreel BJ. 1981. Cell polarity: An examination of its behavioral expression and its consequences for polymorphonuclear leukocyte chemotaxis. J Cell Biol 89: 585-592.