-
1
-
-
0242330126
-
Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling
-
Goumans MJ, Valdimarsdottir G, Itoh S, Lebrin F, Larsson J, Mummery C, et al. Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling. Mol Cell. 2003;12:817-28.
-
(2003)
Mol Cell
, vol.12
, pp. 817-828
-
-
Goumans, M.J.1
Valdimarsdottir, G.2
Itoh, S.3
Lebrin, F.4
Larsson, J.5
Mummery, C.6
-
2
-
-
34548508972
-
The activin A-follistatin system: Potent regulator of human extracellular matrix mineralization
-
Eijken M, Swagemakers S, Koedam M, Steenbergen C, Derkx P, Uitterlinden AG, et al. The activin A-follistatin system: potent regulator of human extracellular matrix mineralization. FASEB J. 2007;21:2949-60.
-
(2007)
FASEB J.
, vol.21
, pp. 2949-2960
-
-
Eijken, M.1
Swagemakers, S.2
Koedam, M.3
Steenbergen, C.4
Derkx, P.5
Uitterlinden, A.G.6
-
3
-
-
84898456500
-
Bone marrow monocyte-/macrophage-derived activin A mediates the osteoclastogenic effect of IL-3 in multiple myeloma
-
Silbermann R, Bolzoni M, Storti P, Guasco D, Bonomini S, Zhou D, et al. Bone marrow monocyte-/macrophage-derived activin A mediates the osteoclastogenic effect of IL-3 in multiple myeloma. Leukemia. 2014;28:951-4.
-
(2014)
Leukemia
, vol.28
, pp. 951-954
-
-
Silbermann, R.1
Bolzoni, M.2
Storti, P.3
Guasco, D.4
Bonomini, S.5
Zhou, D.6
-
4
-
-
79955977357
-
The yin and yang of activin A
-
Sozzani S, Musso T. The yin and yang of Activin A. Blood. 2011;117:5013-5.
-
(2011)
Blood
, vol.117
, pp. 5013-5015
-
-
Sozzani, S.1
Musso, T.2
-
5
-
-
77950438331
-
Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease
-
Vallet S, Mukherjee S, Vaghela N, Hideshima T, Fulciniti M, Pozzi S, et al. Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease. Proc Natl Acad Sci U S A. 2010;107:5124-9.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 5124-5129
-
-
Vallet, S.1
Mukherjee, S.2
Vaghela, N.3
Hideshima, T.4
Fulciniti, M.5
Pozzi, S.6
-
6
-
-
84867135322
-
Circulating activin-A is elevated in patients with advanced multiple myeloma and correlates with extensive bone involvement and inferior survival; No alterations post-lenalidomide and dexamethasone therapy
-
Terpos E, Kastritis E, Christoulas D, Gkotzamanidou M, Eleutherakis-Papaiakovou E, Kanellias N, et al. Circulating activin-A is elevated in patients with advanced multiple myeloma and correlates with extensive bone involvement and inferior survival; no alterations post-lenalidomide and dexamethasone therapy. Ann Oncol. 2012;23:2681-6.
-
(2012)
Ann Oncol.
, vol.23
, pp. 2681-2686
-
-
Terpos, E.1
Kastritis, E.2
Christoulas, D.3
Gkotzamanidou, M.4
Eleutherakis-Papaiakovou, E.5
Kanellias, N.6
-
7
-
-
84861681431
-
New insights into the mechanisms of activin action and inhibition
-
Walton KL, Makanji Y, Harrison CA. New insights into the mechanisms of activin action and inhibition. Mol Cell Endocrinol. 2012;359:2-12.
-
(2012)
Mol Cell Endocrinol.
, vol.359
, pp. 2-12
-
-
Walton, K.L.1
Makanji, Y.2
Harrison, C.A.3
-
8
-
-
0027525105
-
Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors
-
Attisano L, Carcamo J, Ventura F, Weis FM, Massague J, Wrana JL. Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors. Cell. 1993;75:671-80.
-
(1993)
Cell
, vol.75
, pp. 671-680
-
-
Attisano, L.1
Carcamo, J.2
Ventura, F.3
Weis, F.M.4
Massague, J.5
Wrana, J.L.6
-
9
-
-
84884538870
-
Activins bind and signal via bone morphogenetic protein receptor type II (BMPR2) in immortalized gonadotrope-like cells
-
Rejon CA, Hancock MA, Li YN, Thompson TB, Hebert TE, Bernard DJ. Activins bind and signal via bone morphogenetic protein receptor type II (BMPR2) in immortalized gonadotrope-like cells. Cell Signal. 2013;25:2717-26.
-
(2013)
Cell Signal
, vol.25
, pp. 2717-2726
-
-
Rejon, C.A.1
Hancock, M.A.2
Li, Y.N.3
Thompson, T.B.4
Hebert, T.E.5
Bernard, D.J.6
-
10
-
-
0028270311
-
Follistatin, an antagonist of activin, is expressed in the spemann organizer and displays direct neuralizing activity
-
Hemmati-Brivanlou A, Kelly OG, Melton DA. Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity. Cell. 1994;77:283-95.
-
(1994)
Cell
, vol.77
, pp. 283-295
-
-
Hemmati-Brivanlou, A.1
Kelly, O.G.2
Melton, D.A.3
-
11
-
-
84879690630
-
Activin, neutrophils, and inflammation: Just coincidence?
-
Sideras P, Apostolou E, Stavropoulos A, Sountoulidis A, Gavriil A, Apostolidou A, et al. Activin, neutrophils, and inflammation: just coincidence? Semin Immunopathol. 2013;35:481-99.
-
(2013)
Semin Immunopathol.
, vol.35
, pp. 481-499
-
-
Sideras, P.1
Apostolou, E.2
Stavropoulos, A.3
Sountoulidis, A.4
Gavriil, A.5
Apostolidou, A.6
-
12
-
-
84860760237
-
Bone morphogenetic proteins induce apoptosis in multiple myeloma cells by smad-dependent repression of MYC
-
Holien T, Vatsveen TK, Hella H, Rampa C, Brede G, Groseth LA, et al. Bone morphogenetic proteins induce apoptosis in multiple myeloma cells by Smad-dependent repression of MYC. Leukemia. 2012;26:1073-80.
-
(2012)
Leukemia
, vol.26
, pp. 1073-1080
-
-
Holien, T.1
Vatsveen, T.K.2
Hella, H.3
Rampa, C.4
Brede, G.5
Groseth, L.A.6
-
13
-
-
84901840766
-
Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin
-
Olsen OE, Wader KF, Misund K, Vatsveen TK, Ro TB, Mylin AK, et al. Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin. Blood Cancer J. 2014;4, e196.
-
(2014)
Blood Cancer J.
, vol.4
, pp. e196
-
-
Olsen, O.E.1
Wader, K.F.2
Misund, K.3
Vatsveen, T.K.4
Ro, T.B.5
Mylin, A.K.6
-
14
-
-
0036085920
-
SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
-
Inman GJ, Nicolas FJ, Callahan JF, Harling JD, Gaster LM, Reith AD, et al. SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol Pharmacol. 2002;62:65-74.
-
(2002)
Mol Pharmacol.
, vol.62
, pp. 65-74
-
-
Inman, G.J.1
Nicolas, F.J.2
Callahan, J.F.3
Harling, J.D.4
Gaster, L.M.5
Reith, A.D.6
-
15
-
-
2442625301
-
Bone morphogenetic protein-5, -6 and -7 inhibit growth and induce apoptosis in human myeloma cells
-
Ro TB, Holt RU, Brenne AT, Hjorth-Hansen H, Waage A, Hjertner O, et al. Bone morphogenetic protein-5, -6 and -7 inhibit growth and induce apoptosis in human myeloma cells. Oncogene. 2004;23:3024-32.
-
(2004)
Oncogene.
, vol.23
, pp. 3024-3032
-
-
Ro, T.B.1
Holt, R.U.2
Brenne, A.T.3
Hjorth-Hansen, H.4
Waage, A.5
Hjertner, O.6
-
16
-
-
84902076173
-
The role of bone morphogenetic proteins in myeloma cell survival
-
Holien T, Sundan A. The role of bone morphogenetic proteins in myeloma cell survival. Cytokine Growth Factor Rev. 2014;25:343-50.
-
(2014)
Cytokine Growth Factor Rev.
, vol.25
, pp. 343-350
-
-
Holien, T.1
Sundan, A.2
-
17
-
-
51049098368
-
BMP-2/4 and BMP-6/7 differentially utilize cell surface receptors to induce osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells
-
Lavery K, Swain P, Falb D, Alaoui-Ismaili MH. BMP-2/4 and BMP-6/7 Differentially Utilize Cell Surface Receptors to Induce Osteoblastic Differentiation of Human Bone Marrow-derived Mesenchymal Stem Cells. J Biol Chem. 2008;283:20948-58.
-
(2008)
J Biol Chem.
, vol.283
, pp. 20948-20958
-
-
Lavery, K.1
Swain, P.2
Falb, D.3
Alaoui-Ismaili, M.H.4
-
18
-
-
84901692001
-
Sotatercept in patients with osteolytic lesions of multiple myeloma
-
Abdulkadyrov KM, Salogub GN, Khuazheva NK, Sherman ML, Laadem A, Barger R, et al. Sotatercept in patients with osteolytic lesions of multiple myeloma. Br J Haematol. 2014;165:814-23.
-
(2014)
Br J Haematol.
, vol.165
, pp. 814-823
-
-
Abdulkadyrov, K.M.1
Salogub, G.N.2
Khuazheva, N.K.3
Sherman, M.L.4
Laadem, A.5
Barger, R.6
-
19
-
-
84898042418
-
Transforming growth factor-beta superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis
-
Suragani RN, Cadena SM, Cawley SM, Sako D, Mitchell D, Li R, et al. Transforming growth factor-beta superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis. Nat Med. 2014;20:408-14.
-
(2014)
Nat Med.
, vol.20
, pp. 408-414
-
-
Suragani, R.N.1
Cadena, S.M.2
Cawley, S.M.3
Sako, D.4
Mitchell, D.5
Li, R.6
-
20
-
-
0035863916
-
Bone morphogenetic protein-4 inhibits proliferation and induces apoptosis of multiple myeloma cells
-
Hjertner O, Hjorth-Hansen H, Borset M, Seidel C, Waage A, Sundan A. Bone morphogenetic protein-4 inhibits proliferation and induces apoptosis of multiple myeloma cells. Blood. 2001;97:516-22.
-
(2001)
Blood
, vol.97
, pp. 516-522
-
-
Hjertner, O.1
Hjorth-Hansen, H.2
Borset, M.3
Seidel, C.4
Waage, A.5
Sundan, A.6
|