A Basal Tone of 2-Arachidonoylglycerol Contributes to Early Oligodendrocyte Progenitor Proliferation by Activating Phosphatidylinositol 3-Kinase (PI3K)/AKT and the Mammalian Target of Rapamycin (MTOR) Pathways

Journal of Neuroimmune Pharmacology

Volumn 10, Issue 2, 2015, Pages 309-317

  Gomez, Oscar ^a   Sanchez Rodriguez, Maria A ^a   Ortega Gutierrez, Silvia ^b   Vazquez Villa, Henar ^b   Guaza, Carmen ^c   Molina Holgado, Francisco ^d   Molina Holgado, Eduardo ^a  

^a HOSPITAL NACIONAL DE PARAPLÉJICOS   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c INSTITUTO CAJAL   (Spain)

^d UNIVERSITY OF ROEHAMPTON   (United Kingdom)

Author keywords

2 AG; cdk2; cyclin E; Diacylglycerol lipase; Oligodendrocyte progenitor; p27

Indexed keywords

2 ARACHIDONOYLGLYCEROL; CYCLIN E; FIBROBLAST GROWTH FACTOR 2; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR AA; PROTEIN KINASE B; 2-ARACHIDONYLGLYCEROL; ACYLGLYCEROL; ARACHIDONIC ACID DERIVATIVE; CANNABINOID RECEPTOR AGONIST; ENDOCANNABINOID; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CELL RENEWAL; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME SYNTHESIS; MYELINATION; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; DRUG EFFECTS; HUMAN; METABOLISM; MOUSE; PHYSIOLOGY; STEM CELL;

ANIMALS; ARACHIDONIC ACIDS; CANNABINOID RECEPTOR AGONISTS; CELL PROLIFERATION; CELLS, CULTURED; ENDOCANNABINOIDS; GLYCERIDES; HUMANS; MICE; OLIGODENDROGLIA; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STEM CELLS; TOR SERINE-THREONINE KINASES;

EID: 84931004065     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-015-9609-x     Document Type: Article

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