-
1
-
-
84885370061
-
Albumin as a versatile platform for drug half-life extension
-
[1] Sleep D, Cameron J, Evans LR. Albumin as a versatile platform for drug half-life extension. Biochim Biophys Acta 2013; 1830: 5526-34.
-
(2013)
Biochim Biophys Acta
, vol.1830
, pp. 5526-5534
-
-
Sleep, D.1
Cameron, J.2
Evans, L.R.3
-
3
-
-
55749111387
-
The pharmacology of PEGylation: Balancing PD with PK to generate novel therapeutics
-
[3] Fishburn CS. The pharmacology of PEGylation: balancing PD with PK to generate novel therapeutics. J Pharm Sci 2008; 97: 4167-83.
-
(2008)
J Pharm Sci
, vol.97
, pp. 4167-4183
-
-
Fishburn, C.S.1
-
4
-
-
12244272391
-
Enhancement of therapeutic protein in vivo activities through glycoengineering
-
[4] Elliott S, Lorenzini T, Asher S, et al. Enhancement of therapeutic protein in vivo activities through glycoengineering. Nat Biotechnol 2003; 21: 414-21.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 414-421
-
-
Elliott, S.1
Lorenzini, T.2
Asher, S.3
-
5
-
-
62149133544
-
Fusion-proteins as biopharmaceuticals--applications and challenges
-
[5] Schmidt SR. Fusion-proteins as biopharmaceuticals--applications and challenges. Curr Opin Drug Discov Devel 2009; 12: 284-95.
-
(2009)
Curr Opin Drug Discov Devel
, vol.12
, pp. 284-295
-
-
Schmidt, S.R.1
-
6
-
-
84867065769
-
Fc-fusion proteins: New developments and future perspectives
-
[6] Czajkowsky DM, Hu J, Shao Z, Pleass RJ. Fc-fusion proteins: new developments and future perspectives. EMBO Mol Med 2012; 4: 1015-28.
-
(2012)
EMBO Mol Med
, vol.4
, pp. 1015-1028
-
-
Czajkowsky, D.M.1
Hu, J.2
Shao, Z.3
Pleass, R.J.4
-
7
-
-
84907204279
-
Albiglutide approved for type 2 diabetes
-
[7] Traynor K. Albiglutide approved for type 2 diabetes. Am J Health Syst Pharm 2014; 71: 888.
-
(2014)
Am J Health Syst Pharm
, vol.71
, pp. 888
-
-
Traynor, K.1
-
8
-
-
77956710095
-
Albinterferon-alpha 2b: A new treatment option for hepatitis C
-
[8] Flisiak R, Flisiak I. Albinterferon-alpha 2b: a new treatment option for hepatitis C. Expert Opin Biol Ther 2010; 10: 1509-15.
-
(2010)
Expert Opin Biol Ther
, vol.10
, pp. 1509-1515
-
-
Flisiak, R.1
Flisiak, I.2
-
9
-
-
84896716673
-
Human serum albumin and p53-activating peptide fusion protein is able to promote apoptosis and deliver fatty acid-modified molecules
-
[9] Joshi MR, Yao N, Myers KA, Li Z. Human serum albumin and p53-activating peptide fusion protein is able to promote apoptosis and deliver fatty acid-modified molecules. PLoS One 2013; 8: c.
-
(2013)
Plos One
, pp. 8
-
-
Joshi, M.R.1
Yao, N.2
Myers, K.A.3
Li, Z.4
-
10
-
-
84928321728
-
Albumin and its application in drug delivery
-
[10] Sleep D. Albumin and its application in drug delivery. Expert Opin Drug Deliv, 2014; 12: 1-20.
-
(2014)
Expert Opin Drug Deliv
, vol.12
, pp. 1-20
-
-
Sleep, D.1
-
11
-
-
20044391816
-
Albumin: Biochemical properties and therapeutic potential
-
[11] Quinlan GJ, Martin GS, Evans TW. Albumin: biochemical properties and therapeutic potential. Hepatology 2005; 41: 1211-9.
-
(2005)
Hepatology
, vol.41
, pp. 1211-1219
-
-
Quinlan, G.J.1
Martin, G.S.2
Evans, T.W.3
-
12
-
-
0026409406
-
Cytosol albumin content in operable breast cancer. Correlations to steroid hormone receptors, other prognostic factors and prognosis
-
[12] Soreide JA, Lea OA, Kvinnsland S. Cytosol albumin content in operable breast cancer. Correlations to steroid hormone receptors, other prognostic factors and prognosis. Acta Oncol 1991; 30: 797-802.
-
(1991)
Acta Oncol
, vol.30
, pp. 797-802
-
-
Soreide, J.A.1
Lea, O.A.2
Kvinnsland, S.3
-
13
-
-
84900865192
-
Bypass mechanisms of resistance to tyrosine kinase inhibition in chronic myelogenous leukaemia
-
[13] Marfe G, Di Stefano C. Bypass mechanisms of resistance to tyrosine kinase inhibition in chronic myelogenous leukaemia. Curr Drug Discov Technol 2014; 11: 145-53.
-
(2014)
Curr Drug Discov Technol
, vol.11
, pp. 145-153
-
-
Marfe, G.1
Di Stefano, C.2
-
14
-
-
0037255597
-
Overview of tag protein fusions: From molecular and biochemical fundamentals to commercial systems
-
[14] Terpe K. Overview of tag protein fusions: from molecular and biochemical fundamentals to commercial systems. Appl Microbiol Biotechnol 2003; 60: 523-33.
-
(2003)
Appl Microbiol Biotechnol
, vol.60
, pp. 523-533
-
-
Terpe, K.1
-
15
-
-
30944464087
-
Fluorescence microscopy today
-
[15] Yuste R. Fluorescence microscopy today. Nat Methods 2005; 2: 902-4.
-
(2005)
Nat Methods
, vol.2
, pp. 902-904
-
-
Yuste, R.1
-
16
-
-
79251538078
-
Recombinant human transferrin: Beyond iron binding and transport
-
[16] Brandsma ME, Jevnikar AM, Ma S. Recombinant human transferrin: beyond iron binding and transport. Biotechnol Adv 2010; 29: 230-8.
-
(2010)
Biotechnol Adv
, vol.29
, pp. 230-238
-
-
Brandsma, M.E.1
Jevnikar, A.M.2
Ma, S.3
-
17
-
-
84860338314
-
The fusion protein of IFN-alpha and apolipoprotein A-I crosses the blood-brain barrier by a saturable transport mechanism
-
[17] Fioravanti J, Medina-Echeverz J, Ardaiz N, et al. The fusion protein of IFN-alpha and apolipoprotein A-I crosses the blood-brain barrier by a saturable transport mechanism. J Immunol 2012; 188: 3988-92.
-
(2012)
J Immunol
, vol.188
, pp. 3988-3992
-
-
Fioravanti, J.1
Medina-Echeverz, J.2
Ardaiz, N.3
-
18
-
-
71849085755
-
A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner
-
[18] Schellenberger V, Wang CW, Geething NC, et al. A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner. Nat Biotechnol 2009; 27: 1186-90.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 1186-1190
-
-
Schellenberger, V.1
Wang, C.W.2
Geething, N.C.3
-
19
-
-
84876081114
-
Antibody-based fusion proteins to target death receptors in cancer
-
[19] de Bruyn M, Bremer E, Helfrich W. Antibody-based fusion proteins to target death receptors in cancer. Cancer Lett 2011; 332: 175-83.
-
(2011)
Cancer Lett
, vol.332
, pp. 175-183
-
-
De Bruyn, M.1
Bremer, E.2
Helfrich, W.3
-
20
-
-
55349100505
-
Optimizing denileukin diftitox (Ontak) therapy
-
[20] Duvic M, Talpur R. Optimizing denileukin diftitox (Ontak) therapy. Future Oncol 2008; 4: 457-69.
-
(2008)
Future Oncol
, vol.4
, pp. 457-469
-
-
Duvic, M.1
Talpur, R.2
-
21
-
-
79959946173
-
Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells
-
[21] Baker K, Qiao SW, Kuo TT, et al. Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells. Proc Natl Acad Sci USA 2011; 108: 9927-32.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 9927-9932
-
-
Baker, K.1
Qiao, S.W.2
Kuo, T.T.3
-
22
-
-
79955646410
-
Modulation of antibody effector function
-
[22] Desjarlais JR, Lazar GA. Modulation of antibody effector function. Exp Cell Res 2011; 317: 1278-85.
-
(2011)
Exp Cell Res
, vol.317
, pp. 1278-1285
-
-
Desjarlais, J.R.1
Lazar, G.A.2
-
24
-
-
84864057941
-
Pharmaceutical aspects of the recombinant human serum albumin dimer: Structural characteristics, biological properties, and medical applications
-
[24] Taguchi K, Chuang VT, Maruyama T, Otagiri M. Pharmaceutical aspects of the recombinant human serum albumin dimer: structural characteristics, biological properties, and medical applications. J Pharm Sci 2012; 101: 3033-46.
-
(2012)
J Pharm Sci
, vol.101
, pp. 3033-3046
-
-
Taguchi, K.1
Chuang, V.T.2
Maruyama, T.3
Otagiri, M.4
-
25
-
-
84856726736
-
Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor
-
[25] Andersen JT, Dalhus B, Cameron J, et al. Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor. Nat Commun 2012; 3: 610.
-
(2012)
Nat Commun
, vol.3
, pp. 610
-
-
Ersen, J.T.1
Dalhus, B.2
Cameron, J.3
-
26
-
-
33847617011
-
Mechanisms of action of glucagon-like peptide 1 in the pancreas
-
[26] Doyle ME, Egan JM. Mechanisms of action of glucagon-like peptide 1 in the pancreas. Pharmacol Ther 2007; 113: 546-93.
-
(2007)
Pharmacol Ther
, vol.113
, pp. 546-593
-
-
Doyle, M.E.1
Egan, J.M.2
-
27
-
-
84881018686
-
Fusion protein linkers: Property, design and functionality
-
[27] Chen X, Zaro JL, Shen WC. Fusion protein linkers: property, design and functionality. Adv Drug Deliv Rev 2012; 65: 1357-69.
-
(2012)
Adv Drug Deliv Rev
, vol.65
, pp. 1357-1369
-
-
Chen, X.1
Zaro, J.L.2
Shen, W.C.3
-
28
-
-
57349168543
-
Pharmacodynamics, pharmacokinetics, safety, and tolerability of albiglutide, a longacting glucagon-like peptide-1 mimetic, in patients with type 2 diabetes
-
[28] Matthews JE, Stewart MW, De Boever EH, et al. Pharmacodynamics, pharmacokinetics, safety, and tolerability of albiglutide, a longacting glucagon-like peptide-1 mimetic, in patients with type 2 diabetes. J Clin Endocrinol Metab 2008; 93: 4810-7.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 4810-4817
-
-
Matthews, J.E.1
Stewart, M.W.2
De Boever, E.H.3
-
29
-
-
0033062612
-
Crystal structure of human serum albumin at 2.5 A resolution
-
[29] Sugio S, Kashima A, Mochizuki S, et al. Crystal structure of human serum albumin at 2.5 A resolution. Protein Eng 1999; 12: 439-46.
-
(1999)
Protein Eng
, vol.12
, pp. 439-446
-
-
Sugio, S.1
Kashima, A.2
Mochizuki, S.3
-
30
-
-
0035659618
-
In vitro and in vivo properties of recombinant human serum albumin from Pichia pastoris purified by a method of short processing time
-
[30] Watanabe H, Yamasaki K, Kragh-Hansen U, et al. In vitro and in vivo properties of recombinant human serum albumin from Pichia pastoris purified by a method of short processing time. Pharm Res 2001; 18: 1775-81.
-
(2001)
Pharm Res
, vol.18
, pp. 1775-1781
-
-
Watanabe, H.1
Yamasaki, K.2
Kragh-Hansen, U.3
-
31
-
-
84905472510
-
Comparison of GLP-1 analogues versus sitagliptin in the management of type 2 diabetes: Systematic review and meta-analysis of head-to-head studies
-
[31] Wang T, Gou Z, Wang F, et al. Comparison of GLP-1 analogues versus sitagliptin in the management of type 2 diabetes: systematic review and meta-analysis of head-to-head studies. PLoS One 2014; 9: e103798.
-
(2014)
Plos One
, vol.9
-
-
Wang, T.1
Gou, Z.2
Wang, F.3
-
33
-
-
1842687009
-
Degradation, receptor binding, insulin secreting and antihyperglycaemic actions of palmitate-derivatised native and Ala8-substituted GLP-1 analogues
-
[33] Green BD, Gault VA, Mooney MH, et al. Degradation, receptor binding, insulin secreting and antihyperglycaemic actions of palmitate-derivatised native and Ala8-substituted GLP-1 analogues. Biol Chem 2004; 385: 169-77.
-
(2004)
Biol Chem
, vol.385
, pp. 169-177
-
-
Green, B.D.1
Gault, V.A.2
Mooney, M.H.3
-
34
-
-
67449086488
-
Exenatide once weekly for the treatment of type 2 diabetes
-
[34] Malone J, Trautmann M, Wilhelm K, et al. Exenatide once weekly for the treatment of type 2 diabetes. Expert Opin Investig Drugs 2009; 18: 359-67.
-
(2009)
Expert Opin Investig Drugs
, vol.18
, pp. 359-367
-
-
Malone, J.1
Trautmann, M.2
Wilhelm, K.3
-
35
-
-
65449189175
-
Safety, tolerability, pharmacodynamics and pharmacokinetics of albiglutide, a longacting glucagon-like peptide-1 mimetic, in healthy subjects
-
[35] Bush MA, Matthews JE, De Boever EH, et al. Safety, tolerability, pharmacodynamics and pharmacokinetics of albiglutide, a longacting glucagon-like peptide-1 mimetic, in healthy subjects. Diabetes Obes Metab 2009; 11: 498-505.
-
(2009)
Diabetes Obes Metab
, vol.11
, pp. 498-505
-
-
Bush, M.A.1
Matthews, J.E.2
De Boever, E.H.3
-
36
-
-
44349157048
-
Preparation and characterization of a novel exendin-4 human serum albumin fusion protein expressed in Pichia pastoris
-
[36] Huang YS, Chen Z, Chen YQ, et al. Preparation and characterization of a novel exendin-4 human serum albumin fusion protein expressed in Pichia pastoris. J Pept Sci 2008; 14: 588-95.
-
(2008)
J Pept Sci
, vol.14
, pp. 588-595
-
-
Huang, Y.S.1
Chen, Z.2
Chen, Y.Q.3
-
37
-
-
84896076107
-
A novel exendin-4 human serum albumin fusion protein, E2HSA, with an extended half-life and good glucoregulatory effect in healthy rhesus monkeys
-
[37] Zhang L, Wang L, Meng Z, et al. A novel exendin-4 human serum albumin fusion protein, E2HSA, with an extended half-life and good glucoregulatory effect in healthy rhesus monkeys. Biochem Biophys Res Commun 2014; 445: 511-6.
-
(2014)
Biochem Biophys Res Commun
, vol.445
, pp. 511-516
-
-
Zhang, L.1
Wang, L.2
Meng, Z.3
-
38
-
-
33644522358
-
Inquiring into the differential action of interferons (IFNs): An IFN-alpha2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-beta
-
[38] Jaitin DA, Roisman LC, Jaks E, et al. Inquiring into the differential action of interferons (IFNs): an IFN-alpha2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-beta. Mol Cell Biol 2006; 26: 1888-97.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 1888-1897
-
-
Jaitin, D.A.1
Roisman, L.C.2
Jaks, E.3
-
39
-
-
20044385757
-
Site of pegylation and polyethylene glycol molecule size attenuate interferon-alpha antiviral and antiproliferative activities through the JAK/STAT signaling pathway
-
[39] Grace MJ, Lee S, Bradshaw S, et al. Site of pegylation and polyethylene glycol molecule size attenuate interferon-alpha antiviral and antiproliferative activities through the JAK/STAT signaling pathway. J Biol Chem 2005; 280: 6327-36.
-
(2005)
J Biol Chem
, vol.280
, pp. 6327-6336
-
-
Grace, M.J.1
Lee, S.2
Bradshaw, S.3
-
40
-
-
0038010128
-
Isolation, structural characterization, and antiviral activity of positional isomers of monopegylated interferon alpha-2a (PEGASYS)
-
[40] Foser S, Schacher A, Weyer KA, et al. Isolation, structural characterization, and antiviral activity of positional isomers of monopegylated interferon alpha-2a (PEGASYS). Protein Expr Purif 2003; 30: 78-87.
-
(2003)
Protein Expr Purif
, vol.30
, pp. 78-87
-
-
Foser, S.1
Schacher, A.2
Weyer, K.A.3
-
41
-
-
0037124398
-
Structural and biological characterization of pegylated recombinant interferon alpha-2b and its therapeutic implications
-
[41] Wang YS, Youngster S, Grace M, et al. Structural and biological characterization of pegylated recombinant interferon alpha-2b and its therapeutic implications. Adv Drug Deliv Rev 2002; 54: 547-70.
-
(2002)
Adv Drug Deliv Rev
, vol.54
, pp. 547-570
-
-
Wang, Y.S.1
Youngster, S.2
Grace, M.3
-
42
-
-
0036827834
-
Pharmacokinetic and pharmacodynamic studies of a human serum albumin-interferonalpha fusion protein in cynomolgus monkeys
-
[42] Osborn BL, Olsen HS, Nardelli B, et al. Pharmacokinetic and pharmacodynamic studies of a human serum albumin-interferonalpha fusion protein in cynomolgus monkeys. J Pharmacol Exp Ther 2002; 303: 540-8.
-
(2002)
J Pharmacol Exp Ther
, vol.303
, pp. 540-548
-
-
Osborn, B.L.1
Olsen, H.S.2
Nardelli, B.3
-
43
-
-
36849040529
-
Albinterferon alpha-2b: A genetic fusion protein for the treatment of chronic hepatitis C
-
[43] Subramanian GM, Fiscella M, Lamouse-Smith A, et al. Albinterferon alpha-2b: a genetic fusion protein for the treatment of chronic hepatitis C. Nat Biotechnol 2007; 25: 1411-9.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 1411-1419
-
-
Subramanian, G.M.1
Fiscella, M.2
Lamouse-Smith, A.3
-
44
-
-
77957376504
-
Albinterferon Alfa-2b was not inferior to pegylated interferon-alpha in a randomized trial of patients with chronic hepatitis C virus genotype 1
-
[44] Zeuzem S, Sulkowski MS, Lawitz EJ, et al. Albinterferon Alfa-2b was not inferior to pegylated interferon-alpha in a randomized trial of patients with chronic hepatitis C virus genotype 1. Gastroenterology 2010; 139: 1257-66.
-
(2010)
Gastroenterology
, vol.139
, pp. 1257-1266
-
-
Zeuzem, S.1
Sulkowski, M.S.2
Lawitz, E.J.3
-
45
-
-
34548393737
-
Circumventing the heterogeneity and instability of human serum albumin-interferon-alpha2b fusion protein by altering its orientation
-
[45] Zhao HL, Xue C, Wang Y, et al. Circumventing the heterogeneity and instability of human serum albumin-interferon-alpha2b fusion protein by altering its orientation. J Biotechnol 2007; 131: 245-52.
-
(2007)
J Biotechnol
, vol.131
, pp. 245-252
-
-
Zhao, H.L.1
Xue, C.2
Wang, Y.3
-
46
-
-
47749104481
-
Increasing the homogeneity, stability and activity of human serum albumin and interferon-alpha2b fusion protein by linker engineering
-
[46] Zhao HL, Yao XQ, Xue C, et al. Increasing the homogeneity, stability and activity of human serum albumin and interferon-alpha2b fusion protein by linker engineering. Protein Expr Purif 2008; 61: 73-7.
-
(2008)
Protein Expr Purif
, vol.61
, pp. 73-77
-
-
Zhao, H.L.1
Yao, X.Q.2
Xue, C.3
-
47
-
-
84863232328
-
Balancing the pharmacokinetics and pharmacodynamics of interferon-alpha2b and human serum albumin fusion protein by proteolytic or reductive cleavage increases its in vivo therapeutic efficacy
-
[47] Zhao HL, Xue C, Du JL, et al. Balancing the pharmacokinetics and pharmacodynamics of interferon-alpha2b and human serum albumin fusion protein by proteolytic or reductive cleavage increases its in vivo therapeutic efficacy. Mol Pharm 2012; 9: 664-70.
-
(2012)
Mol Pharm
, vol.9
, pp. 664-670
-
-
Zhao, H.L.1
Xue, C.2
Du, J.L.3
-
48
-
-
33644770486
-
Crystallization of a 2: 2 complex of granulocyte-colony stimulating factor (GCSF) with the ligand-binding region of the GCSF receptor
-
[48] Honjo E, Tamada T, Maeda Y, et al. Crystallization of a 2: 2 complex of granulocyte-colony stimulating factor (GCSF) with the ligand-binding region of the GCSF receptor. Acta Crystallogr Sect F Struct Biol Cryst Commun 2005; 61: 788-90.
-
(2005)
Acta Crystallogr Sect F Struct Biol Cryst Commun
, vol.61
, pp. 788-790
-
-
Honjo, E.1
Tamada, T.2
Maeda, Y.3
-
49
-
-
47549107114
-
Pegfilgrastim; a neutrophil mediated granulocyte colony stimulating factor-expanding uses in cancer chemotherapy
-
[49] Morishita M, Leonard RC. Pegfilgrastim; a neutrophil mediated granulocyte colony stimulating factor-expanding uses in cancer chemotherapy. Expert Opin Biol Ther 2008; 8: 993-1001.
-
(2008)
Expert Opin Biol Ther
, vol.8
, pp. 993-1001
-
-
Morishita, M.1
Leonard, R.C.2
-
50
-
-
84896394783
-
Efficacy and safety of balugrastim compared with pegfilgrastim in patients with breast cancer receiving chemotherapy
-
[50] Volovat C, Gladkov OA, Bondarenko IM, et al. Efficacy and safety of balugrastim compared with pegfilgrastim in patients with breast cancer receiving chemotherapy. Clin Breast Cancer 2014; 14: 101-8.
-
(2014)
Clin Breast Cancer
, vol.14
, pp. 101-108
-
-
Volovat, C.1
Gladkov, O.A.2
Bondarenko, I.M.3
-
51
-
-
0035081112
-
Pharmacokinetics of recombinant factor IX in relation to age of the patient: Implications for dosing in prophylaxis
-
[51] Bjorkman S, Shapiro AD, Berntorp E. Pharmacokinetics of recombinant factor IX in relation to age of the patient: implications for dosing in prophylaxis. Haemophilia 2001; 7: 133-9.
-
(2001)
Haemophilia
, vol.7
, pp. 133-139
-
-
Bjorkman, S.1
Shapiro, A.D.2
Berntorp, E.3
-
52
-
-
70449461639
-
Genetic fusion to albumin improves the pharmacokinetic properties of factor IX
-
[52] Metzner HJ, Weimer T, Kronthaler U, et al. Genetic fusion to albumin improves the pharmacokinetic properties of factor IX. Thromb Haemost 2009; 102: 634-44.
-
(2009)
Thromb Haemost
, vol.102
, pp. 634-644
-
-
Metzner, H.J.1
Weimer, T.2
Kronthaler, U.3
-
53
-
-
12644255693
-
Enhanced albumin uptake by rat tumors
-
[53] Wunder A, Stehle G, Sinn H, et al. Enhanced albumin uptake by rat tumors. Int J Oncol 1997; 11: 497-507.
-
(1997)
Int J Oncol
, vol.11
, pp. 497-507
-
-
Wunder, A.1
Stehle, G.2
Sinn, H.3
-
54
-
-
0030842545
-
Plasma protein (Albumin) catabolism by the tumor itself--implications for tumor metabolism and the genesis of cachexia
-
[54] Stehle G, Sinn H, Wunder A, et al. Plasma protein (albumin) catabolism by the tumor itself--implications for tumor metabolism and the genesis of cachexia. Crit Rev Oncol Hematol 1997; 26: 77-100.
-
(1997)
Crit Rev Oncol Hematol
, vol.26
, pp. 77-100
-
-
Stehle, G.1
Sinn, H.2
Wunder, A.3
-
55
-
-
0028121374
-
Regulation of vascular endothelial barrier function
-
[55] Lum H, Malik AB. Regulation of vascular endothelial barrier function. Am J Physiol 1994; 267: L223-41.
-
(1994)
Am J Physiol
, vol.267
, pp. 41-223
-
-
Lum, H.1
Malik, A.B.2
-
56
-
-
0034000453
-
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: A review
-
[56] Maeda H, Wu J, Sawa T, et al. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release 2000; 65: 271-84.
-
(2000)
J Control Release
, vol.65
, pp. 271-284
-
-
Maeda, H.1
Wu, J.2
Sawa, T.3
-
57
-
-
52649119391
-
Improved effectiveness of nanoparticle albumin-bound (Nab) paclitaxel versus polysorbatebased docetaxel in multiple xenografts as a function of HER2 and SPARC status
-
[57] Desai NP, Trieu V, Hwang LY, et al. Improved effectiveness of nanoparticle albumin-bound (nab) paclitaxel versus polysorbatebased docetaxel in multiple xenografts as a function of HER2 and SPARC status. Anticancer Drugs 2008; 19: 899-909.
-
(2008)
Anticancer Drugs
, vol.19
, pp. 899-909
-
-
Desai, N.P.1
Trieu, V.2
Hwang, L.Y.3
-
58
-
-
84922553334
-
Expression of secreted protein acidic and rich in cysteine (SPARC) in breast cancer and response to neoadjuvant chemotherapydagger
-
[58] Lindner JL, Loibl S, Denkert C, et al. Expression of secreted protein acidic and rich in cysteine (SPARC) in breast cancer and response to neoadjuvant chemotherapydagger. Ann Oncol 2014; 26: 95-100.
-
(2014)
Ann Oncol
, vol.26
, pp. 95-100
-
-
Lindner, J.L.1
Loibl, S.2
Denkert, C.3
-
59
-
-
56949084877
-
Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles
-
[59] Kratz F. Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles. J Control Release 2008; 132: 171-83.
-
(2008)
J Control Release
, vol.132
, pp. 171-183
-
-
Kratz, F.1
-
60
-
-
77954215302
-
Current strategies to target p53 in cancer
-
[60] Chen F, Wang W, El-Deiry WS. Current strategies to target p53 in cancer. Biochem Pharmacol 2010; 80: 724-30.
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 724-730
-
-
Chen, F.1
Wang, W.2
El-Deiry, W.S.3
-
61
-
-
14644437751
-
MDM2 is a central node in the p53 pathway: 12 years and counting
-
[61] Bond GL, Hu W, Levine AJ. MDM2 is a central node in the p53 pathway: 12 years and counting. Curr Cancer Drug Targets 2005; 5: 3-8.
-
(2005)
Curr Cancer Drug Targets
, vol.5
, pp. 3-8
-
-
Bond, G.L.1
Hu, W.2
Levine, A.J.3
-
62
-
-
3042523534
-
Small-molecule inhibitors of the p53 suppressor HDM2: Have protein-protein interactions come of age as drug targets?
-
[62] Fischer PM, Lane DP. Small-molecule inhibitors of the p53 suppressor HDM2: have protein-protein interactions come of age as drug targets? Trends Pharmacol Sci 2004; 25: 343-6.
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 343-346
-
-
Fischer, P.M.1
Lane, D.P.2
-
63
-
-
0035940401
-
Peptides from the amino terminal mdm-2-binding domain of p53, designed from conformational analysis, are selectively cytotoxic to transformed cells
-
[63] Kanovsky M, Raffo A, Drew L, et al. Peptides from the amino terminal mdm-2-binding domain of p53, designed from conformational analysis, are selectively cytotoxic to transformed cells. Proc Natl Acad Sci USA 2001; 98: 12438-43.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 12438-12443
-
-
Kanovsky, M.1
Raffo, A.2
Drew, L.3
-
64
-
-
84898669985
-
Drug carriers for the delivery of therapeutic peptides
-
[64] Du AW, Stenzel MH. Drug carriers for the delivery of therapeutic peptides. Biomacromolecules 2014; 15: 1097-114.
-
(2014)
Biomacromolecules
, vol.15
, pp. 1097-1114
-
-
Du, A.W.1
Stenzel, M.H.2
-
65
-
-
84864631153
-
Cell-penetrating peptides: Classes, origin, and current landscape
-
[65] Milletti F. Cell-penetrating peptides: classes, origin, and current landscape. Drug Discov Today 2012; 17: 850-60.
-
(2012)
Drug Discov Today
, vol.17
, pp. 850-860
-
-
Milletti, F.1
-
66
-
-
32944482677
-
Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer
-
[66] Gradishar WJ, Tjulandin S, Davidson N, et al. Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer. J Clin Oncol 2005; 23: 7794-803.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7794-7803
-
-
Gradishar, W.J.1
Tjulandin, S.2
Davidson, N.3
-
67
-
-
84922572602
-
A phase 1B/2 study of aldoxorubicin in patients with soft tissue sarcoma
-
[67] Chawla SP, Chua VS, Hendifar AF, et al. A phase 1B/2 study of aldoxorubicin in patients with soft tissue sarcoma. Cancer 2015; 121: 570-9.
-
(2015)
Cancer
, vol.121
, pp. 570-579
-
-
Chawla, S.P.1
Chua, V.S.2
Hendifar, A.F.3
-
68
-
-
33144488817
-
Insulin detemir: From concept to clinical experience
-
[68] Home P, Kurtzhals P. Insulin detemir: from concept to clinical experience. Expert Opin Pharmacother 2006; 7: 325-43.
-
(2006)
Expert Opin Pharmacother
, vol.7
, pp. 325-343
-
-
Home, P.1
Kurtzhals, P.2
-
69
-
-
0032720125
-
Fatty acid binding to human serum albumin: New insights from crystallographic studies
-
[69] Curry S, Brick P, Franks NP. Fatty acid binding to human serum albumin: new insights from crystallographic studies. Biochim Biophys Acta 1999; 1441: 131-40.
-
(1999)
Biochim Biophys Acta
, vol.1441
, pp. 131-140
-
-
Curry, S.1
Brick, P.2
Franks, N.P.3
-
70
-
-
52049105453
-
Recent trends in targeted anticancer prodrug and conjugate design
-
[70] Singh Y, Palombo M, Sinko PJ. Recent trends in targeted anticancer prodrug and conjugate design. Curr Med Chem 2008; 15: 1802-26.
-
(2008)
Curr Med Chem
, vol.15
, pp. 1802-1826
-
-
Singh, Y.1
Palombo, M.2
Sinko, P.J.3
-
71
-
-
84902665558
-
Pt(IV) prodrugs designed to bind non-covalently to human serum albumin for drug delivery
-
[71] Zheng YR, Suntharalingam K, Johnstone TC, et al. Pt(IV) prodrugs designed to bind non-covalently to human serum albumin for drug delivery. J Am Chem Soc 2014; 136: 8790-8.
-
(2014)
J am Chem Soc
, vol.136
, pp. 8790-8798
-
-
Zheng, Y.R.1
Suntharalingam, K.2
Johnstone, T.C.3
-
72
-
-
84859738027
-
Selective domain stabilization as a strategy to reduce human serum albumin-human granulocyte colony stimulating factor aggregation rate
-
[72] Cordes AA, Carpenter JF, Randolph TW. Selective domain stabilization as a strategy to reduce human serum albumin-human granulocyte colony stimulating factor aggregation rate. J Pharm Sci 2012; 101: 2009-16.
-
(2012)
J Pharm Sci
, vol.101
, pp. 2009-2016
-
-
Cordes, A.A.1
Carpenter, J.F.2
Randolph, T.W.3
-
73
-
-
0037027919
-
Albutropin: A growth hormone-albumin fusion with improved pharmacokinetics and pharmacodynamics in rats and monkeys
-
[73] Osborn BL, Sekut L, Corcoran M, et al. Albutropin: a growth hormone-albumin fusion with improved pharmacokinetics and pharmacodynamics in rats and monkeys. Eur J Pharmacol 2002; 456: 149-58.
-
(2002)
Eur J Pharmacol
, vol.456
, pp. 149-158
-
-
Osborn, B.L.1
Sekut, L.2
Corcoran, M.3
-
74
-
-
2342628432
-
Effect of albumin fusion on the biodistribution of interleukin-2
-
[74] Yao Z, Dai W, Perry J, et al. Effect of albumin fusion on the biodistribution of interleukin-2. Cancer Immunol Immunother 2004; 53: 404-10.
-
(2004)
Cancer Immunol Immunother
, vol.53
, pp. 404-410
-
-
Yao, Z.1
Dai, W.2
Perry, J.3
-
75
-
-
19944428668
-
Development of a long-acting insulin analog using albumin fusion technology
-
[75] Duttaroy A, Kanakaraj P, Osborn BL, et al. Development of a long-acting insulin analog using albumin fusion technology. Diabetes 2005; 54: 251-8.
-
(2005)
Diabetes
, vol.54
, pp. 251-258
-
-
Duttaroy, A.1
Kanakaraj, P.2
Osborn, B.L.3
|