Stromal cell-mediated glycolytic switch in CLL cells involves Notch-c-Myc signaling

Blood

Volumn 125, Issue 22, 2015, Pages 3432-3436

  Jitschin, Regina ^a   Braun, Martina ^a   Qorraj, Mirjeta ^a   Saul, Domenica ^a   Le Blanc, Katarina ^b   Zenz, Thorsten ^c,d   Mougiakakos, Dimitrios ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYCLIN B1; ENOLASE; ENOLASE 1; GLUCOSE TRANSPORTER 3; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCOLYTIC ENZYME; HEXOKINASE; HEXOKINASE 2; JAGGED1; LACTATE DEHYDROGENASE; LACTATE DEHYDROGENASE A; LACTIC ACID; MESSENGER RNA; MYC PROTEIN; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH3 RECEPTOR; NOTCH4 RECEPTOR; PYRUVATE DEHYDROGENASE KINASE; PYRUVATE DEHYDROGENASE KINASE 1; UNCLASSIFIED DRUG; MYC PROTEIN, HUMAN;

ARTICLE; BIOENERGY; BONE MARROW STROMA CELL; CELL CONTACT; CELL ENERGY; CELL FUNCTION; CELL SURVIVAL; CELL VIABILITY; CHRONIC LYMPHATIC LEUKEMIA; COLORIMETRY; ENERGY YIELD; GENE EXPRESSION; GENE SWITCHING; GENETIC TRANSCRIPTION; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLYCOLYSIS; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE PHOSPHORYLATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STROMA CELL; UPREGULATION; AEROBIC METABOLISM; BONE MARROW CELL; CELL CULTURE; CELL RESPIRATION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY;

AEROBIOSIS; BONE MARROW CELLS; CELL RESPIRATION; CELLS, CULTURED; GLYCOLYSIS; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; PROTO-ONCOGENE PROTEINS C-MYC; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; STROMAL CELLS;

EID: 84930966151     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-10-607036     Document Type: Article

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