메뉴 건너뛰기




Volumn 6, Issue 2, 2015, Pages 238-251

JAG: A computational tool to evaluate the role of gene-sets in complex traits

Author keywords

Biological pathway; Gene set analysis; Genetic association; GWAS; Pathway analysis

Indexed keywords

ANALYTICAL ERROR; ARTICLE; BIOINFORMATICS; CROHN DISEASE; DATA ANALYSIS; DATA ANALYSIS SOFTWARE; GENE FREQUENCY; GENE IDENTIFICATION; GENE LINKAGE DISEQUILIBRIUM; GENE MAPPING; GENE SET ANALYSIS; GENETIC ALGORITHM; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC DATABASE; GENOTYPE; HUMAN; INTERMETHOD COMPARISON; MULTIFACTORIAL INHERITANCE; PERFORMANCE MEASUREMENT SYSTEM; POWER ANALYSIS; PROCESS CONTROL; PROCESS DESIGN; QUALITY CONTROL; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEM ANALYSIS; VALIDATION PROCESS; WEB BROWSER;

EID: 84930944446     PISSN: None     EISSN: 20734425     Source Type: Journal    
DOI: 10.3390/genes6020238     Document Type: Article
Times cited : (9)

References (31)
  • 2
    • 84863980709 scopus 로고    scopus 로고
    • Genetic architectures of psychiatric disorders: The emerging picture and its implications
    • Sullivan, P.F.; Daly, M.J.; O’Donovan, M. Genetic architectures of psychiatric disorders: The emerging picture and its implications. Nat. Rev. Genet 2012, 13, 537-551.
    • (2012) Nat. Rev. Genet , vol.13 , pp. 537-551
    • Sullivan, P.F.1    Daly, M.J.2    O’donovan, M.3
  • 9
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • International Schizophrenia Consortium
    • International Schizophrenia Consortium; Purcell, S.M.; Wray, N.R.; Stone, J.L.; Visscher, P.M.; O’Donovan, M.C.; Sullivan, P.M.; Sklar, P. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 2009, 460, 748-752.
    • (2009) Nature , vol.460 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2    Stone, J.L.3    Visscher, P.M.4    O’donovan, M.C.5    Sullivan, P.M.6    Sklar, P.7
  • 10
    • 42649123990 scopus 로고    scopus 로고
    • Sizing up human height variation
    • Visscher, P.M. Sizing up human height variation. Nat. Genet 2008, 40, 489-490.
    • (2008) Nat. Genet , vol.40 , pp. 489-490
    • Visscher, P.M.1
  • 11
    • 53649098737 scopus 로고    scopus 로고
    • Pathway analysis of seven common diseases assessed by genome-wide association
    • Torkamani, A.; Topol, E.J.; Schork, N.J. Pathway analysis of seven common diseases assessed by genome-wide association. Genomics 2008, 92, 265-272.
    • (2008) Genomics , vol.92 , pp. 265-272
    • Torkamani, A.1    Topol, E.J.2    Schork, N.J.3
  • 15
    • 84861123691 scopus 로고    scopus 로고
    • Ten years of pathway analysis: Current approaches and outstanding challenges
    • Khatri, P.; Sirota, M.; Butte, A.J. Ten years of pathway analysis: current approaches and outstanding challenges. PLoS Comput. Biol. 2012, 8, e1002375.
    • (2012) Plos Comput. Biol , vol.8
    • Khatri, P.1    Sirota, M.2    Butte, A.J.3
  • 16
    • 79952467494 scopus 로고    scopus 로고
    • GATES: A rapid and powerful gene-based association test using extended Simes procedure
    • Li, M.X.; Gui, H.S.; Kwan, J.S.; Sham, P.C. GATES: A rapid and powerful gene-based association test using extended Simes procedure. Am. J. Hum. Genet 2011, 88, 283-293.
    • (2011) Am. J. Hum. Genet , vol.88 , pp. 283-293
    • Li, M.X.1    Gui, H.S.2    Kwan, J.S.3    Sham, P.C.4
  • 18
    • 36249029788 scopus 로고    scopus 로고
    • Pathway-based approaches for analysis of genomewide association studies
    • Wang, K.; Li, M.; Bucan, M. Pathway-based approaches for analysis of genomewide association studies. Am. J. Hum. Genet 2007, 81, 1278-1283.
    • (2007) Am. J. Hum. Genet , vol.81 , pp. 1278-1283
    • Wang, K.1    Li, M.2    Bucan, M.3
  • 19
    • 77953123145 scopus 로고    scopus 로고
    • Insights into colon cancer etiology via a regularized approach to gene set analysis of GWAS data
    • Chen, L.S.; Hutter, C.M.; Potter, J.D.; Liu, Y.; Prentice, R.L.; Peters, U.; Hsu, L. Insights into colon cancer etiology via a regularized approach to gene set analysis of GWAS data. Am. J. Hum. Genet 2010, 86, 860-871.
    • (2010) Am. J. Hum. Genet , vol.86 , pp. 860-871
    • Chen, L.S.1    Hutter, C.M.2    Potter, J.D.3    Liu, Y.4    Prentice, R.L.5    Peters, U.6    Hsu, L.7
  • 20
    • 78549251736 scopus 로고    scopus 로고
    • Analysing biological pathways in genome-wide association studies
    • Wang, K.; Li, M.; Hakonarson, H. Analysing biological pathways in genome-wide association studies. Nat. Rev. Genet 2010, 11, 843-854.
    • (2010) Nat. Rev. Genet , vol.11 , pp. 843-854
    • Wang, K.1    Li, M.2    Hakonarson, H.3
  • 21
    • 80053478943 scopus 로고    scopus 로고
    • Comparisons of seven algorithms for pathway analysis using the WTCCC Crohn’s Disease dataset
    • Gui, H.; Li, M.; Sham, P.C.; Cherny, S.S. Comparisons of seven algorithms for pathway analysis using the WTCCC Crohn’s Disease dataset. BMC Res. Notes 2011, 4, doi:10.1186/1756-0500-4-386.
    • (2011) BMC Res. Notes , vol.4
    • Gui, H.1    Li, M.2    Sham, P.C.3    Cherny, S.S.4
  • 23
    • 34249663294 scopus 로고    scopus 로고
    • Analyzing gene expression data in terms of gene sets: Methodological issues
    • Goeman, J.J.; Buhlmann, P. Analyzing gene expression data in terms of gene sets: Methodological issues. Bioinformatics 2007, 23, 980-987.
    • (2007) Bioinformatics , vol.23 , pp. 980-987
    • Goeman, J.J.1    Buhlmann, P.2
  • 24
    • 75149134369 scopus 로고    scopus 로고
    • A new permutation strategy of pathway-based approach for genome-wide association study
    • Guo, Y.F.; Li, J.; Chen, Y.; Zhang, L.S.; Deng, H.W. A new permutation strategy of pathway-based approach for genome-wide association study. BMC Bioinform. 2009, 10, doi:10.1186/1471-2105-10-429.
    • (2009) BMC Bioinform , vol.10
    • Guo, Y.F.1    Li, J.2    Chen, Y.3    Zhang, L.S.4    Deng, H.W.5
  • 26
    • 82355190215 scopus 로고    scopus 로고
    • Evaluation of an approximation method for assessment of overall significance of multiple-dependent tests in a genomewide association study
    • Moskvina, V.; O’Dushlaine, C.; Purcell, S.; Craddock, N.; Holmans, P.; O’Donovan, M.C. Evaluation of an approximation method for assessment of overall significance of multiple-dependent tests in a genomewide association study. Genet Epidemiol. 2011, 35, 861-866.
    • (2011) Genet Epidemiol , vol.35 , pp. 861-866
    • Moskvina, V.1    O’dushlaine, C.2    Purcell, S.3    Craddock, N.4    Holmans, P.5    O’Donovan, M.C.6
  • 27
    • 84863304598 scopus 로고    scopus 로고
    • R Development Core Team, The R Foundation for Statistical Computing: Vienna, Austria
    • R Development Core Team. R: A Language and Environment for Statistical Computing; The R Foundation for Statistical Computing: Vienna, Austria, 2011.
    • (2011) R: A Language and Environment for Statistical Computing
  • 28
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • Price, A.L.; Patterson, N.J.; Plenge, R.M.; Weinblatt, M.E.; Shadick, N.A.; Reich, D. Principal components analysis corrects for stratification in genome-wide association studies. Nat. Genet 2006, 38, 904-909.
    • (2006) Nat. Genet , vol.38 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3    Weinblatt, M.E.4    Shadick, N.A.5    Reich, D.6
  • 30
    • 84862499271 scopus 로고    scopus 로고
    • Pathway analysis of genomic data: Concepts, methods, and prospects for future development
    • Ramanan, V.K.; Shen, L.; Moore, J.H.; Saykin, A.J. Pathway analysis of genomic data: Concepts, methods, and prospects for future development. Trends Genet 2012, 28, 323-332.
    • (2012) Trends Genet , vol.28 , pp. 323-332
    • Ramanan, V.K.1    Shen, L.2    Moore, J.H.3    Saykin, A.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.