Newly developed apolipoprotein A-I mimetic peptide promotes macrophage reverse cholesterol transport in vivo

International Journal of Cardiology

Volumn 192, Issue , 2015, Pages 82-88

  Shimizu, Tomohiko ^a   Tanigawa, Hiroyuki ^a   Miura, Shin Ichiro ^a   Kuwano, Takashi ^a   Takata, Kohei ^a   Suematsu, Yasunori ^a   Imaizumi, Satoshi ^a   Yahiro, Eiji ^a   Zhang, Bo ^a   Uehara, Yoshinari ^a   Saku, Keijiro ^a  

^a FUKUOKA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apolipoprotein A I mimetic peptides; ATP binding cassette transporter A1; Cholesterol efflux; High density lipoprotein; Reverse cholesterol transport

Indexed keywords

ABC TRANSPORTER A1; CHOLESTEROL ESTER TRANSFER PROTEIN; FUKUOKA APOLIPOPROTEIN A I MIMETIC PEPTIDE; PEPTIDOMIMETIC AGENT; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; UNCLASSIFIED DRUG; ABCA1 PROTEIN, MOUSE; APOLIPOPROTEIN A1; BIOMIMETIC MATERIAL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CATABOLISM; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MEGADOSE; EX VIVO STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; ISOTACHOPHORESIS; LIPID ANALYSIS; LIPOPROTEIN BLOOD LEVEL; LOW DRUG DOSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE CHOLESTEROL TRANSPORT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; ANIMAL; ATHEROSCLEROSIS; MACROPHAGE; METABOLISM; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; APOLIPOPROTEIN A-I; ATHEROSCLEROSIS; ATP BINDING CASSETTE TRANSPORTER 1; BIOLOGICAL TRANSPORT; BIOMIMETIC MATERIALS; CHOLESTEROL, HDL; MACROPHAGES; MICE; MICE, TRANSGENIC;

EID: 84930941165     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2015.05.012     Document Type: Article

References (31)

1. P. Barter, A.M. Gotto, J.C. LaRosa, J. Maroni, M. Szarek, and S.M. Grundy HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events N. Engl. J. Med. 357 2007 1301 1310
2. D.J. Gordon, and B.M. Rifkind High-density lipoprotein - the clinical implications of recent studies N. Engl. J. Med. 321 1989 1311 1316
3. A.V. Khera, M. Cuchel, M. de la Llera-Moya, A. Rodrigues, M.F. Burke, and K. Jafri Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis N. Engl. J. Med. 364 2011 127 135
4. S.E. Nissen, J.C. Tardif, S.J. Nicholls, J.H. Revkin, C.L. Shear, and W.T. Duggan Effect of torcetrapib on the progression of coronary atherosclerosis N. Engl. J. Med. 356 2007 1304 1316
5. T.F. Luscher, S. Taddei, J.C. Kaski, J.W. Jukema, D. Kallend, and T. Munzel Vascular effects and safety of dalcetrapib in patients with or at risk of coronary heart disease: the dal-VESSEL randomized clinical trial Eur. Heart J. 33 2012 857 865
6. T. Teramoto, M. Shirakawa, M. Kikuchi, M. Nakagomi, S. Tamura, and H.K. Surks Efficacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib in Japanese patients with dyslipidemia Atherosclerosis 230 2013 52 60
7. G. Cao, T.P. Beyer, Y. Zhang, R.J. Schmidt, Y.Q. Chen, and S.L. Cockerham Evacetrapib is a novel, potent, and selective inhibitor of cholesteryl ester transfer protein that elevates HDL cholesterol without inducing aldosterone or increasing blood pressure J. Lipid Res. 52 2011 2169 2176
8. A. Iwata, S. Miura, B. Zhang, S. Imaizumi, Y. Uehara, and M. Shiomi Antiatherogenic effects of newly developed apolipoprotein A-I mimetic peptide/phospholipid complexes against aortic plaque burden in Watanabe-heritable hyperlipidemic rabbits Atherosclerosis 218 2011 300 307
9. S.E. Nissen, T. Tsunoda, E.M. Tuzcu, P. Schoenhagen, C.J. Cooper, and M. Yasin Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: a randomized controlled trial JAMA 290 2003 2292 2300
10. M. Navab, G.M. Anantharamaiah, S. Hama, D.W. Garber, M. Chaddha, and G. Hough Oral administration of an Apo A-I mimetic peptide synthesized from d-amino acids dramatically reduces atherosclerosis in mice independent of plasma cholesterol Circulation 105 2002 290 292
11. X. Li, K.Y. Chyu, J.R. Faria Neto, J. Yano, N. Nathwani, and C. Ferreira Differential effects of apolipoprotein A-I-mimetic peptide on evolving and established atherosclerosis in apolipoprotein E-null mice Circulation 110 2004 1701 1705
12. Y. Uehara, S. Ando, E. Yahiro, K. Oniki, M. Ayaori, and S. Abe FAMP, a novel apoA-I mimetic peptide, suppresses aortic plaque formation through promotion of biological HDL function in ApoE-deficient mice J. Am. Heart Assoc. 2 2013 e000048 10.1161/JAHA.113.000048
13. E. Carballo-Jane, Z. Chen, E. O'Neill, J. Wang, C. Burton, and C.H. Chang ApoA-I mimetic peptides promote pre-beta HDL formation in vivo causing remodeling of HDL and triglyceride accumulation at higher dose Bioorg. Med. Chem. 18 2010 8669 8678
14. S. Yona, S.E. Heinsbroek, L. Peiser, S. Gordon, M. Perretti, and R.J. Flower Impaired phagocytic mechanism in annexin 1 null macrophages Br. J. Pharmacol. 148 2006 469 477
15. S. Usui, Y. Hara, S. Hosaki, and M. Okazaki A new on-line dual enzymatic method for simultaneous quantification of cholesterol and triglycerides in lipoproteins by HPLC J. Lipid Res. 43 2002 805 814
16. M. Okazaki, S. Usui, M. Ishigami, N. Sakai, T. Nakamura, and Y. Matsuzawa Identification of unique lipoprotein subclasses for visceral obesity by component analysis of cholesterol profile in high-performance liquid chromatography Arterioscler. Thromb. Vasc. Biol. 25 2005 578 584
17. B. Zhang, T. Kaneshi, T. Ohta, and K. Saku Relation between insulin resistance and fast-migrating LDL subfraction as characterized by capillary isotachophoresis J. Lipid Res. 46 2005 2265 2277
18. B. Zhang, S. Miura, P. Fan, K. Kumagai, K. Takeuchi, and Y. Uehara ApoA-I/phosphatidylcholine discs remodels fast-migrating HDL into slow-migrating HDL as characterized by capillary isotachophoresis Atherosclerosis 188 2006 95 101
19. G. Schmitz, C. Mollers, and V. Richter Analytical capillary isotachophoresis of human serum lipoproteins Electrophoresis 18 1997 1807 1813
20. E. Favari, I. Zanotti, F. Zimetti, N. Ronda, F. Bernini, and G.H. Rothblat Probucol inhibits ABCA1-mediated cellular lipid efflux Arterioscler. Thromb. Vasc. Biol. 24 2004 2345 2350
21. G.H. Rothblat, M. de la Llera-Moya, E. Favari, P.G. Yancey, and G. Kellner-Weibel Cellular cholesterol flux studies: methodological considerations Atherosclerosis 163 2002 1 8
22. Y. Zhang, J.R. Da Silva, M. Reilly, J.T. Billheimer, G.H. Rothblat, and D.J. Rader Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo J. Clin. Invest. 115 2005 2870 2874
23. H. Tanigawa, J.T. Billheimer, J. Tohyama, Y. Zhang, G. Rothblat, and D.J. Rader Expression of cholesteryl ester transfer protein in mice promotes macrophage reverse cholesterol transport Circulation 116 2007 1267 1273
24. E.T. Alexander, G.L. Weibel, M.R. Joshi, C. Vedhachalam, M. de la Llera-Moya, and G.H. Rothblat Macrophage reverse cholesterol transport in mice expressing ApoA-I Milano Arterioscler. Thromb. Vasc. Biol. 29 2009 1496 1501
25. U.J. Tietge, C. Maugeais, W. Cain, D. Grass, J.M. Glick, and F.C. de Beer Overexpression of secretory phospholipase A(2) causes rapid catabolism and altered tissue uptake of high density lipoprotein cholesteryl ester and apolipoprotein A-I J. Biol. Chem. 275 2000 10077 10084
26. C. Maugeais, U.J. Tietge, U.C. Broedl, D. Marchadier, W. Cain, and M.G. McCoy Dose-dependent acceleration of high-density lipoprotein catabolism by endothelial lipase Circulation 108 2003 2121 2126
27. M. de la Llera-Moya, D. Drazul-Schrader, B.F. Asztalos, M. Cuchel, D.J. Rader, and G.H. Rothblat The ability to promote efflux via ABCA1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from macrophages Arterioscler. Thromb. Vasc. Biol. 30 2010 796 801
28. J.S. Troutt, W.E. Alborn, M.K. Mosior, J. Dai, A.T. Murphy, and T.P. Beyer An apolipoprotein A-I mimetic dose-dependently increases the formation of prebeta1 HDL in human plasma J. Lipid Res. 49 2008 581 587
29. Q. Xie, S.P. Zhao, and F. Li D-4F, an apolipoprotein A-I mimetic peptide, promotes cholesterol efflux from macrophages via ATP-binding cassette transporter A1 Tohoku J. Exp. Med. 220 2010 223 228
30. S. Yamamoto, H. Tanigawa, X. Li, Y. Komaru, J.T. Billheimer, and D.J. Rader Pharmacologic suppression of hepatic ATP-binding cassette transporter 1 activity in mice reduces high-density lipoprotein cholesterol levels but promotes reverse cholesterol transport Circulation 124 2011 1382 1390
31. F. Rinninger, N. Wang, R. Ramakrishnan, X.C. Jiang, and A.R. Tall Probucol enhances selective uptake of HDL-associated cholesteryl esters in vitro by a scavenger receptor B-I-dependent mechanism Arterioscler. Thromb. Vasc. Biol. 19 1999 1325 1332