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Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 15, 2015, Pages 2923-2926

Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity

(7) Peters, Hannah L a Jochmans, Dirk b De Wilde, Adriaan H c Posthuma, Clara C c Snijder, Eric J c Neyts, Johan b Seley Radtke, Katherine L a

a UNIVERSITY OF MARYLAND BALTIMORE COUNTY (United States)

b REGA INSTITUTE FOR MEDICAL RESEARCH (Belgium)

c LEIDEN UNIVERSITY MEDICAL CENTER (Netherlands)

Author keywords

Acyclovir; Antiviral; Coronaviruses; Fleximers; MERS CoV; Nucleosides; SARS

Indexed keywords

ACICLOVIR; ANTIVIRUS AGENT; NUCLEOSIDE ANALOG; NUCLEOSIDE;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CORONAVIRUS INFECTION; CYTOTOXIC CONCENTRATION; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; EC50; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; NONHUMAN; SARS CORONAVIRUS; VERO CELL LINE; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; CHLOROCEBUS AETHIOPS; CORONAVIRIDAE; CORONAVIRUS INFECTIONS; DRUG EFFECTS; HUMAN; HUMAN CORONAVIRUS NL63; PHYSIOLOGY; VIRUS REPLICATION;

CORONAVIRUS; SARS CORONAVIRUS;

ACYCLOVIR; ANIMALS; ANTIVIRAL AGENTS; CERCOPITHECUS AETHIOPS; CORONAVIRUS; CORONAVIRUS INFECTIONS; CORONAVIRUS NL63, HUMAN; DRUG DESIGN; HUMANS; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; NUCLEOSIDES; SARS VIRUS; VERO CELLS; VIRUS REPLICATION;

EID: 84930924977 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2015.05.039 Document Type: Article

Times cited : (77)

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