Design, synthesis and biological evaluation of paralleled Aza resveratrol-chalcone compounds as potential anti-inflammatory agents for the treatment of acute lung injury

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 15, 2015, Pages 2998-3004

  Chen, Wenbo ^a   Ge, Xiangting ^b   Xu, Fengli ^b   Zhang, Yali ^a   Liu, Zhiguo ^a   Pan, Jialing ^a   Song, Jiao ^a   Dai, Yuanrong ^b   Zhou, Jianmin ^a   Feng, Jianpeng ^a   Liang, Guang ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL AND YUYING CHILDREN S HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Acute lung injury; Anti inflammatory; Aza resveratrol; Chalcone; Parallel

Indexed keywords

ANTIINFLAMMATORY AGENT; CHALCONE DERIVATIVE; HETEROCYCLIC COMPOUND; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; RESVERATROL; TUMOR NECROSIS FACTOR ALPHA; STILBENE DERIVATIVE; TUMOR NECROSIS FACTOR;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMISTRY; DRUG EFFECTS; HUMAN; IMMUNOLOGY; LUNG; PATHOLOGY;

ACUTE LUNG INJURY; ANIMALS; ANTI-INFLAMMATORY AGENTS; AZA COMPOUNDS; CELL LINE; CHALCONES; HUMANS; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; LUNG; MACROPHAGES; MICE; STILBENES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84930923964     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.05.030     Document Type: Article

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