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Volumn 308, Issue 11, 2015, Pages G955-G963

β-Nicotinamide adenine dinucleotide acts at prejunctional adenosine A1receptors to suppress inhibitory musculomotor neurotransmission in guinea pig colon and human jejunum

Author keywords

Enteric neuromuscular transmission; Intestinal motility; Purinergic receptors; Smooth muscle

Indexed keywords

2' DEOXY 6 N METHYLADENOSINE 3',5' BISPHOSPHATE; 4 (2 IODO 6 METHYLAMINO 9H PURIN 9 YL) 2 PHOSPHONOOXYBICYCLO[3.1.0]HEXANE 1 METHANOL; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR AGONIST; NICOTINAMIDE ADENINE DINUCLEOTIDE; PURINERGIC P2Y RECEPTOR ANTAGONIST; 2-CHLORO-N(6)CYCLOPENTYLADENOSINE; 2-IODO-N(6)-METHYL-(N)-METHANOCARBA-2'-DEOXYADENOSINE-3',5'-BISPHOSPHATE; ADENOSINE; ADENOSINE DIPHOSPHATE; DEOXYADENOSINE PHOSPHATE; LIGAND; N(6)-METHYL-2'-DEOXYADENOSINE 3',5'-DIPHOSPHATE;

EID: 84930910595     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00430.2014     Document Type: Article
Times cited : (12)

References (68)
  • 2
    • 0030845603 scopus 로고    scopus 로고
    • Non-adrenergic non-cholinergic (NANC) transmission to smooth muscle: 35 years on
    • Bennett MR. Non-adrenergic non-cholinergic (NANC) transmission to smooth muscle: 35 years on. Prog Neurobiol 52: 159–195, 1997.
    • (1997) Prog Neurobiol , vol.52 , pp. 159-195
    • Bennett, M.R.1
  • 3
    • 0015925399 scopus 로고
    • Intestinal motility increased by tetrodotoxin, lidocaine, and procaine
    • Biber B, Fara J. Intestinal motility increased by tetrodotoxin, lidocaine, and procaine. Experientia 29: 551–552, 1973.
    • (1973) Experientia , vol.29 , pp. 551-552
    • Biber, B.1    Fara, J.2
  • 4
    • 0001627970 scopus 로고
    • Inhibition of the smooth muscle on the taenia coli
    • Burnstock G, Campbell G, Bennett M, Holman ME. Inhibition of the smooth muscle on the taenia coli. Nature 200: 581–582, 1963.
    • (1963) Nature , vol.200 , pp. 581-582
    • Burnstock, G.1    Campbell, G.2    Bennett, M.3    Holman, M.E.4
  • 5
    • 0015393308 scopus 로고
    • Purinergic nerves
    • Burnstock G. Purinergic nerves. Pharmacol Rev 24: 509–581, 1972.
    • (1972) Pharmacol Rev , vol.24 , pp. 509-581
    • Burnstock, G.1
  • 6
    • 84869224240 scopus 로고    scopus 로고
    • Purinergic signaling in the gastrointestinal tract
    • Burnstock G. Purinergic signaling in the gastrointestinal tract. World J Gastrointest Pathophysiol 2: 31–34, 2011.
    • (2011) World J Gastrointest Pathophysiol , vol.2 , pp. 31-34
    • Burnstock, G.1
  • 7
    • 0021891160 scopus 로고
    • Mucosal responses evoked by stimulation of ganglion cell somas in the submucosal plexus of the guinea-pig ileum
    • Carey HV, Cooke HJ, Zafirova M. Mucosal responses evoked by stimulation of ganglion cell somas in the submucosal plexus of the guinea-pig ileum. J Physiol 364: 69–79, 1985.
    • (1985) J Physiol , vol.364 , pp. 69-79
    • Carey, H.V.1    Cooke, H.J.2    Zafirova, M.3
  • 8
    • 10044241601 scopus 로고    scopus 로고
    • Induction of novel agonist selectivity for the ADP-activated P2Y1 receptor versus the ADP-activated P2Y12 and P2Y13 receptors by conformational constraint of an ADP analog
    • Chhatriwala M, Ravi RG, Patel RI, Boyer JL, Jacobson KA, Harden TK. Induction of novel agonist selectivity for the ADP-activated P2Y1 receptor versus the ADP-activated P2Y12 and P2Y13 receptors by conformational constraint of an ADP analog. J Pharmacol Exp Ther 311: 1038–1043, 2004.
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 1038-1043
    • Chhatriwala, M.1    Ravi, R.G.2    Patel, R.I.3    Boyer, J.L.4    Jacobson, K.A.5    Harden, T.K.6
  • 9
    • 0026694246 scopus 로고
    • Suppression of nicotinic synaptic transmission by adenosine in myenteric ganglia of the guinea-pig gastric antrum
    • Christofi FL, Tack J, Wood JD. Suppression of nicotinic synaptic transmission by adenosine in myenteric ganglia of the guinea-pig gastric antrum. Eur J Pharmacol 216: 17–22, 1992.
    • (1992) Eur J Pharmacol , vol.216 , pp. 17-22
    • Christofi, F.L.1    Tack, J.2    Wood, J.D.3
  • 10
    • 0027301590 scopus 로고
    • Presynaptic inhibition by adenosine A1 receptors on guinea pig small intestinal myenteric neurons
    • Christofi FL, Wood JD. Presynaptic inhibition by adenosine A1 receptors on guinea pig small intestinal myenteric neurons. Gastroenterology 104: 1420–1429, 1993.
    • (1993) Gastroenterology , vol.104 , pp. 1420-1429
    • Christofi, F.L.1    Wood, J.D.2
  • 11
    • 0027999584 scopus 로고
    • Electrophysiological subtypes of inhibitory P1 purinoceptors on myenteric neurones of guinea-pig small bowel
    • Christofi FL, Wood JD. Electrophysiological subtypes of inhibitory P1 purinoceptors on myenteric neurones of guinea-pig small bowel. Br J Pharmacol 113: 703–710, 1994.
    • (1994) Br J Pharmacol , vol.113 , pp. 703-710
    • Christofi, F.L.1    Wood, J.D.2
  • 12
    • 48449083479 scopus 로고    scopus 로고
    • Purinergic receptors and gastrointestinal secretomotor function
    • Christofi FL. Purinergic receptors and gastrointestinal secretomotor function. Purinergic Signal 4: 213–236, 2008.
    • (2008) Purinergic Signal , vol.4 , pp. 213-236
    • Christofi, F.L.1
  • 13
    • 0035829177 scopus 로고    scopus 로고
    • Differential gene expression of adenosine A1, A2a, A2b, and A3 receptors in the human enteric nervous system
    • Christofi FL, Zhang H, Yu JG, Guzman J, Xue J, Kim M, Wang YZ, Cooke HJ. Differential gene expression of adenosine A1, A2a, A2b, and A3 receptors in the human enteric nervous system. J Comp Neurol 439: 46–64, 2001.
    • (2001) J Comp Neurol , vol.439 , pp. 46-64
    • Christofi, F.L.1    Zhang, H.2    Yu, J.G.3    Guzman, J.4    Xue, J.5    Kim, M.6    Wang, Y.Z.7    Cooke, H.J.8
  • 14
    • 79953811059 scopus 로고    scopus 로고
    • Relationship between interstitial cells of Cajal, fibroblast-like cells and inhibitory motor nerves in the internal anal sphincter
    • Cobine CA, Hennig GW, Kurahashi M, Sanders KM, Ward SM, Keef KD. Relationship between interstitial cells of Cajal, fibroblast-like cells and inhibitory motor nerves in the internal anal sphincter. Cell Tissue Res 344: 17–30, 2011.
    • (2011) Cell Tissue Res , vol.344 , pp. 17-30
    • Cobine, C.A.1    Hennig, G.W.2    Kurahashi, M.3    Sanders, K.M.4    Ward, S.M.5    Keef, K.D.6
  • 15
  • 16
    • 0025802771 scopus 로고
    • The nature of noncholinergic membrane potential responses to transmural stimulation in guinea pig ileum
    • Crist JR, He XD, Goyal RK. The nature of noncholinergic membrane potential responses to transmural stimulation in guinea pig ileum. Gastroenterology 100: 1006–1015, 1991.
    • (1991) Gastroenterology , vol.100 , pp. 1006-1015
    • Crist, J.R.1    He, X.D.2    Goyal, R.K.3
  • 17
    • 84859717451 scopus 로고    scopus 로고
    • Adenosine 5-diphosphate-ribose is a neural regulator in primate and murine large intestine along with β-NAD+
    • Durnin L, Hwang SJ, Ward SM, Sanders KM, Mutafova-Yambolieva VN. Adenosine 5-diphosphate-ribose is a neural regulator in primate and murine large intestine along with β-NAD+. J Physiol 590: 1921–1941, 2012.
    • (2012) J Physiol , vol.590 , pp. 1921-1941
    • Durnin, L.1    Hwang, S.J.2    Ward, S.M.3    Sanders, K.M.4    Mutafova-Yambolieva, V.N.5
  • 18
    • 84874022843 scopus 로고    scopus 로고
    • Differential release of β-NAD+ and ATP upon activation of enteric motor neurons in primate and murine colons
    • Durnin L, Sanders KM, Mutafova-Yambolieva VN. Differential release of β-NAD+ and ATP upon activation of enteric motor neurons in primate and murine colons. Neurogastroenterol Motil 25: 194–204, 2013.
    • (2013) Neurogastroenterol Motil , vol.25 , pp. 194-204
    • Durnin, L.1    Sanders, K.M.2    Mutafova-Yambolieva, V.N.3
  • 20
    • 33645817897 scopus 로고    scopus 로고
    • Neurogenic secretion mediated by the purinergic P2Y1 receptor in guineapig small intestine
    • Fang X, Hu HZ, Gao N, Liu S, Wang GD, Wang XY, Xia Y, Wood JD. Neurogenic secretion mediated by the purinergic P2Y1 receptor in guineapig small intestine. Eur J Pharmacol 536: 113–122, 2006.
    • (2006) Eur J Pharmacol , vol.536 , pp. 113-122
    • Fang, X.1    Hu, H.Z.2    Gao, N.3    Liu, S.4    Wang, G.D.5    Wang, X.Y.6    Xia, Y.7    Wood, J.D.8
  • 22
    • 33749431716 scopus 로고    scopus 로고
    • P2Y1 receptors mediate inhibitory purinergic neuromuscular transmission in the human colon
    • Gallego D, Hernandez P, Clave P, Jimenez M. P2Y1 receptors mediate inhibitory purinergic neuromuscular transmission in the human colon. Am J Physiol Gastrointest Liver Physiol 291: G584–G594, 2006.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.291 , pp. G584-G594
    • Gallego, D.1    Hernandez, P.2    Clave, P.3    Jimenez, M.4
  • 24
    • 84859727440 scopus 로고    scopus 로고
    • Purinergic neuromuscular transmission is absent in the colon of P2Y1 knocked out mice
    • Gallego D, Gil V, Martinez-Cutillas M, Mane N, Martin MT, Jimenez M. Purinergic neuromuscular transmission is absent in the colon of P2Y1 knocked out mice. J Physiol 590: 1943–1956, 2012.
    • (2012) J Physiol , vol.590 , pp. 1943-1956
    • Gallego, D.1    Gil, V.2    Martinez-Cutillas, M.3    Mane, N.4    Martin, M.T.5    Jimenez, M.6
  • 27
    • 33847070816 scopus 로고    scopus 로고
    • Stimulation of adenosine A1 and A2A receptors by AMP in the submucosal plexus of guinea pig small intestine
    • Gao N, Hu HZ, Liu S, Gao C, Xia Y, Wood JD. Stimulation of adenosine A1 and A2A receptors by AMP in the submucosal plexus of guinea pig small intestine. Am J Physiol Gastrointest Liver Physiol 292: G492–G500, 2007.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292 , pp. G492-G500
    • Gao, N.1    Hu, H.Z.2    Liu, S.3    Gao, C.4    Xia, Y.5    Wood, J.D.6
  • 29
    • 80053603869 scopus 로고    scopus 로고
    • Evidence for β-nicotinamide adenine dinucleotide as a purinergic, inhibitory neurotransmitter in doubt
    • Goyal RK. Evidence for β-nicotinamide adenine dinucleotide as a purinergic, inhibitory neurotransmitter in doubt. Gastroenterology 141: e27–e28, 2011.
    • (2011) Gastroenterology , vol.141
    • Goyal, R.K.1
  • 30
    • 70350523345 scopus 로고    scopus 로고
    • P2Y1 receptors mediate inhibitory neuromuscular transmission in the rat colon
    • Grasa L, Gil V, Gallego D, Martin MT, Jimenez M. P2Y1 receptors mediate inhibitory neuromuscular transmission in the rat colon. Br J Pharmacol 158: 1641–1652, 2009.
    • (2009) Br J Pharmacol , vol.158 , pp. 1641-1652
    • Grasa, L.1    Gil, V.2    Gallego, D.3    Martin, M.T.4    Jimenez, M.5
  • 31
    • 0038116602 scopus 로고    scopus 로고
    • Slow excitatory synaptic transmission mediated by P2Y1 receptors in the guinea-pig enteric nervous system
    • Hu HZ, Gao N, Zhu MX, Liu S, Ren J, Gao C, Xia Y, Wood JD. Slow excitatory synaptic transmission mediated by P2Y1 receptors in the guinea-pig enteric nervous system. J Physiol 550: 493–504, 2003.
    • (2003) J Physiol , vol.550 , pp. 493-504
    • Hu, H.Z.1    Gao, N.2    Zhu, M.X.3    Liu, S.4    Ren, J.5    Gao, C.6    Xia, Y.7    Wood, J.D.8
  • 32
    • 79251542230 scopus 로고    scopus 로고
    • Mutafova-Yambolieva VN. β-Nicotinamide adenine dinucleotide is an enteric inhibitory neurotransmitter in human and nonhuman primate colons
    • Hwang SJ, Durnin L, Dwyer L, Rhee PL, Ward SM, Koh SD, Sanders KM, Mutafova-Yambolieva VN. β-Nicotinamide adenine dinucleotide is an enteric inhibitory neurotransmitter in human and nonhuman primate colons. Gastroenterology 140: 608–617, 2011.
    • (2011) Gastroenterology , vol.140 , pp. 608-617
    • Hwang, S.J.1    Durnin, L.2    Dwyer, L.3    Rhee, P.L.4    Ward, S.M.5    Koh, S.D.6    Sanders, K.M.7
  • 33
    • 84859701311 scopus 로고    scopus 로고
    • P2Y1 purinoreceptors are fundamental to inhibitory motor control of murine colonic excitability and transit
    • Hwang SJ, Blair PJ, Durnin L, Mutafova-Yambolieva V, Sanders KM, Ward SM. P2Y1 purinoreceptors are fundamental to inhibitory motor control of murine colonic excitability and transit. J Physiol 590: 1957–1972, 2012.
    • (2012) J Physiol , vol.590 , pp. 1957-1972
    • Hwang, S.J.1    Blair, P.J.2    Durnin, L.3    Mutafova-Yambolieva, V.4    Sanders, K.M.5    Ward, S.M.6
  • 34
    • 0027198587 scopus 로고
    • Enteric inhibitory neural regulation of human colonic circular muscle: Role of nitric oxide
    • Keef KD, Du C, Ward SM, McGregor B, Sanders KM. Enteric inhibitory neural regulation of human colonic circular muscle: role of nitric oxide. Gastroenterology 105: 1009–1016, 1993.
    • (1993) Gastroenterology , vol.105 , pp. 1009-1016
    • Keef, K.D.1    Du, C.2    Ward, S.M.3    McGregor, B.4    Sanders, K.M.5
  • 35
  • 36
    • 79251577093 scopus 로고    scopus 로고
    • A functional role for the “fibroblast-like cells” in gastrointestinal smooth muscles
    • Kurahashi M, Zheng H, Dwyer L, Ward SM, Koh SD, Sanders KM. A functional role for the “fibroblast-like cells” in gastrointestinal smooth muscles. J Physiol 589: 697–710, 2011.
    • (2011) J Physiol , vol.589 , pp. 697-710
    • Kurahashi, M.1    Zheng, H.2    Dwyer, L.3    Ward, S.M.4    Koh, S.D.5    Sanders, K.M.6
  • 37
    • 84863112914 scopus 로고    scopus 로고
    • Platelet-derived growth factor receptor-α-positive cells in the tunica muscularis of human colon
    • Kurahashi M, Nakano Y, Hennig GW, Ward SM, Sanders KM. Platelet-derived growth factor receptor-α-positive cells in the tunica muscularis of human colon. J Cell Mol Med 16: 1397–1404, 2012.
    • (2012) J Cell Mol Med , vol.16 , pp. 1397-1404
    • Kurahashi, M.1    Nakano, Y.2    Hennig, G.W.3    Ward, S.M.4    Sanders, K.M.5
  • 39
    • 0035542643 scopus 로고    scopus 로고
    • Activation of presynaptic A1-receptors by endogenous adenosine inhibits acetylcholine release in the guinea-pig ileum
    • Lee JJ, Talubmook C, Parsons ME. Activation of presynaptic A1-receptors by endogenous adenosine inhibits acetylcholine release in the guinea-pig ileum. J Auton Pharmacol 21: 29–38, 2001.
    • (2001) J Auton Pharmacol , vol.21 , pp. 29-38
    • Lee, J.J.1    Talubmook, C.2    Parsons, M.E.3
  • 41
    • 0023113567 scopus 로고
    • Potent adenosine receptor antagonists that are selective for the A1 receptor subtype
    • Martinson EA, Johnson RA, Wells JN. Potent adenosine receptor antagonists that are selective for the A1 receptor subtype. Mol Pharmacol 31: 247–252, 1987.
    • (1987) Mol Pharmacol , vol.31 , pp. 247-252
    • Martinson, E.A.1    Johnson, R.A.2    Wells, J.N.3
  • 43
    • 84866672170 scopus 로고    scopus 로고
    • Neuronal and extraneuronal release of ATP and NAD+ in smooth muscle
    • Mutafova-Yambolieva VN. Neuronal and extraneuronal release of ATP and NAD+ in smooth muscle. IUBMB Life 64: 817–824, 2012.
    • (2012) IUBMB Life , vol.64 , pp. 817-824
    • Mutafova-Yambolieva, V.N.1
  • 44
    • 84907896279 scopus 로고    scopus 로고
    • The purinergic neurotransmitter revisited: A single substance or multiple players?
    • Mutafova-Yambolieva VN, Durnin L. The purinergic neurotransmitter revisited: a single substance or multiple players? Pharmacol Ther 144: 162–191, 2014.
    • (2014) Pharmacol Ther , vol.144 , pp. 162-191
    • Mutafova-Yambolieva, V.N.1    Durnin, L.2
  • 46
    • 0029064938 scopus 로고
    • A1-receptor-mediated effect of adenosine on the release of acetylcholine from the myenteric plexus: Role and localization of ecto-ATPase and 5′-nucleotidase
    • Nitahara K, Kittel A, Liang SD, Vizi ES. A1-receptor-mediated effect of adenosine on the release of acetylcholine from the myenteric plexus: role and localization of ecto-ATPase and 5′-nucleotidase. Neuroscience 67: 159–168, 1995.
    • (1995) Neuroscience , vol.67 , pp. 159-168
    • Nitahara, K.1    Kittel, A.2    Liang, S.D.3    Vizi, E.S.4
  • 47
    • 0023162312 scopus 로고
    • Purinergic inhibition in the small intestinal myenteric plexus of the guinea-pig
    • Palmer JM, Wood JD, Zafirov DH. Purinergic inhibition in the small intestinal myenteric plexus of the guinea-pig. J Physiol 387: 357–369, 1987.
    • (1987) J Physiol , vol.387 , pp. 357-369
    • Palmer, J.M.1    Wood, J.D.2    Zafirov, D.H.3
  • 48
    • 0033058757 scopus 로고    scopus 로고
    • Emerging roles of purinergic signaling in gastrointestinal epithelial secretion and hepatobiliary function
    • Roman RM, Fitz JG. Emerging roles of purinergic signaling in gastrointestinal epithelial secretion and hepatobiliary function. Gastroenterology 116: 964–979, 1999.
    • (1999) Gastroenterology , vol.116 , pp. 964-979
    • Roman, R.M.1    Fitz, J.G.2
  • 49
    • 0026493324 scopus 로고
    • Non-adrenergic, non-cholinergic inhibitory responses to nerve stimulation in rat colonic circular muscle
    • Serio R, Mule F, Postorino A. Non-adrenergic, non-cholinergic inhibitory responses to nerve stimulation in rat colonic circular muscle. Exp Physiol 77: 119–127, 1992.
    • (1992) Exp Physiol , vol.77 , pp. 119-127
    • Serio, R.1    Mule, F.2    Postorino, A.3
  • 50
    • 84873430133 scopus 로고    scopus 로고
    • Neurogastroenterology: Colonic motor neurotransmission—is β-NAD+ in control?
    • Smith K. Neurogastroenterology: colonic motor neurotransmission—is β-NAD+ in control? Nat Rev Gastroenterol Hepatol 10: 64, 2013.
    • (2013) Nat Rev Gastroenterol Hepatol , vol.10 , pp. 64
    • Smith, K.1
  • 51
    • 0027391138 scopus 로고
    • Nitric oxide mediates inhibitory nerve input in human and canine jejunum
    • Stark ME, Bauer AJ, Sarr MG, Szurszewski JH. Nitric oxide mediates inhibitory nerve input in human and canine jejunum. Gastroenterology 104: 398–409, 1993.
    • (1993) Gastroenterology , vol.104 , pp. 398-409
    • Stark, M.E.1    Bauer, A.J.2    Sarr, M.G.3    Szurszewski, J.H.4
  • 52
    • 0036097385 scopus 로고    scopus 로고
    • Effects of endomorphin-1 and -2 on μ-opioid receptors in myenteric neurons and in the peristaltic reflex in rat small intestine
    • Storr M, Hahn A, Gaffal E, Saur D, Allescher HD. Effects of endomorphin-1 and -2 on μ-opioid receptors in myenteric neurons and in the peristaltic reflex in rat small intestine. Clin Exp Pharmacol Physiol 29: 428–434, 2002.
    • (2002) Clin Exp Pharmacol Physiol , vol.29 , pp. 428-434
    • Storr, M.1    Hahn, A.2    Gaffal, E.3    Saur, D.4    Allescher, H.D.5
  • 54
    • 0016276850 scopus 로고
    • Action of tetrodotoxin on spontaneous electrical activity of some smooth muscle preparations
    • Tonini M, Lecchini S, Frigo G, Crema A. Action of tetrodotoxin on spontaneous electrical activity of some smooth muscle preparations. Eur J Pharmacol 29: 236–240, 1974.
    • (1974) Eur J Pharmacol , vol.29 , pp. 236-240
    • Tonini, M.1    Lecchini, S.2    Frigo, G.3    Crema, A.4
  • 55
    • 0027463184 scopus 로고
    • Adenosine receptor-blocking xanthines as inhibitors of phosphodiesterase isozymes
    • Ukena D, Schudt C, Sybrecht GW. Adenosine receptor-blocking xanthines as inhibitors of phosphodiesterase isozymes. Biochem Pharmacol 45: 847–851, 1993.
    • (1993) Biochem Pharmacol , vol.45 , pp. 847-851
    • Ukena, D.1    Schudt, C.2    Sybrecht, G.W.3
  • 58
  • 59
    • 84882553979 scopus 로고    scopus 로고
    • Cellular neurophysiology of enteric neurons
    • edited by Johnson LR, Kaunitz JD, Ghishan FK, Merchant JL, Said HM, Wood JD. San Diego: Elsevier
    • Wood JD. Cellular neurophysiology of enteric neurons. In: Physiology of the Gastrointestinal Tract, edited by Johnson LR, Kaunitz JD, Ghishan FK, Merchant JL, Said HM, Wood JD. San Diego: Elsevier, 2012.
    • (2012) In: Physiology of the Gastrointestinal Tract
    • Wood, J.D.1
  • 60
    • 0014823530 scopus 로고
    • Electrical activity from single neurons in Auerbach’s plexus
    • Wood JD. Electrical activity from single neurons in Auerbach’s plexus. Am J Physiol 219: 159–169, 1970.
    • (1970) Am J Physiol , vol.219 , pp. 159-169
    • Wood, J.D.1
  • 61
    • 0015589481 scopus 로고
    • Effects of atropine, tetrodotoxin and lidocaine on rebound excitation of guinea-pig small intestine
    • Wood JD, Marsh DR. Effects of atropine, tetrodotoxin and lidocaine on rebound excitation of guinea-pig small intestine. J Pharmacol Exp Ther 184: 590–598, 1973.
    • (1973) J Pharmacol Exp Ther , vol.184 , pp. 590-598
    • Wood, J.D.1    Marsh, D.R.2
  • 62
    • 0022458461 scopus 로고
    • Electrical and contractile behavior of large intestinal musculature of piebald mouse model for Hirschsprung’s disease
    • Wood JD, Brann LR, Vermillion DL. Electrical and contractile behavior of large intestinal musculature of piebald mouse model for Hirschsprung’s disease. Dig Dis Sci 31: 638–650, 1986.
    • (1986) Dig Dis Sci , vol.31 , pp. 638-650
    • Wood, J.D.1    Brann, L.R.2    Vermillion, D.L.3
  • 63
    • 33750510100 scopus 로고    scopus 로고
    • The enteric purinergic P2Y1 receptor
    • Wood JD. The enteric purinergic P2Y1 receptor. Curr Opin Pharmacol 6: 564–570, 2006.
    • (2006) Curr Opin Pharmacol , vol.6 , pp. 564-570
    • Wood, J.D.1
  • 65
    • 0033039742 scopus 로고    scopus 로고
    • ATP is a mediator of the fast inhibitory junction potential in human jejunal circular smooth muscle
    • Xue L, Farrugia G, Sarr MG, Szurszewski JH. ATP is a mediator of the fast inhibitory junction potential in human jejunal circular smooth muscle. Am J Physiol Gastrointest Liver Physiol 276: G1373–G1379, 1999.
    • (1999) Am J Physiol Gastrointest Liver Physiol , vol.276 , pp. G1373-G1379
    • Xue, L.1    Farrugia, G.2    Sarr, M.G.3    Szurszewski, J.H.4
  • 66
    • 0034025847 scopus 로고    scopus 로고
    • Actions of endomorphins on synaptic transmission of Aδ-fibers in spinal cord dorsal horn neurons
    • Yajiri Y, Huang LY. Actions of endomorphins on synaptic transmission of Aδ-fibers in spinal cord dorsal horn neurons. J Biomed Sci 7: 226–231, 2000.
    • (2000) J Biomed Sci , vol.7 , pp. 226-231
    • Yajiri, Y.1    Huang, L.Y.2
  • 67
    • 0030933655 scopus 로고    scopus 로고
    • A potent and selective endogenous agonist for the μ-opiate receptor
    • Zadina JE, Hackler L, Ge LJ, Kastin AJ. A potent and selective endogenous agonist for the μ-opiate receptor. Nature 386: 499–502, 1997.
    • (1997) Nature , vol.386 , pp. 499-502
    • Zadina, J.E.1    Hackler, L.2    Ge, L.J.3    Kastin, A.J.4
  • 68
    • 0028020202 scopus 로고
    • Effects of cyclopiazonic acid on contractility and ecto-ATPase activity in guinea-pig urinary bladder and vas deferens
    • Ziganshin AU, Hoyle CH, Ziganshina LE, Burnstock G. Effects of cyclopiazonic acid on contractility and ecto-ATPase activity in guinea-pig urinary bladder and vas deferens. Br J Pharmacol 113: 669–674, 1994.
    • (1994) Br J Pharmacol , vol.113 , pp. 669-674
    • Ziganshin, A.U.1    Hoyle, C.H.2    Ziganshina, L.E.3    Burnstock, G.4


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