Meta-analysis of BRAF mutation as a predictive biomarker of benefit from anti-EGFR monoclonal antibody therapy for RAS wild-type metastatic colorectal cancer

British Journal of Cancer

Volumn 112, Issue 12, 2015, Pages 1888-1894

  Rowland, A ^a   Dias, M M ^a,b   Wiese, M D ^b   Kichenadasse, G ^a   McKinnon, R A ^a   Karapetis, C S ^a   Sorich, M J ^a  

^a FLINDERS UNIVERSITY   (Australia)

^b UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

Author keywords

anti EGFR monoclonal antibodies; BRAF V600E mutation; metastatic colorectal cancer; predictive biomarkers

Indexed keywords

B RAF KINASE; CETUXIMAB; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; MONOCLONAL ANTIBODY; OXALIPLATIN; PANITUMUMAB; BRAF PROTEIN, HUMAN; EGFR PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR RECEPTOR;

ARTICLE; CANCER COMBINATION CHEMOTHERAPY; DISEASE MARKER; GENE MUTATION; HUMAN; META ANALYSIS; METASTATIC COLORECTAL CANCER; PREDICTIVE VALUE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SYSTEMATIC REVIEW; ANTAGONISTS AND INHIBITORS; COLORECTAL NEOPLASMS; ENZYMOLOGY; GENETICS; METASTASIS; MUTATION; PATHOLOGY;

ANTIBODIES, MONOCLONAL; COLORECTAL NEOPLASMS; HUMANS; MUTATION; NEOPLASM METASTASIS; PROTO-ONCOGENE PROTEINS B-RAF; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 84930872726     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2015.173     Document Type: Article

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